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79 studies found for:    "gene therapy" OR "gene transfer" OR "virus delivery" | retrovirus
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Rank Status Study
1 Completed Bone Marrow Cell Gene Transfer in Individuals With Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Genetic: Retrovirus Construct
2 Active, not recruiting Pilot and Feasibility Study of Hematopoietic Stem Cell Gene Transfer for the Wiskott-Aldrich Syndrome
Condition: Wiskott-Aldrich Syndrome
Intervention: Biological: Retrovirus-mediated gene transfer
3 Withdrawn Safety and Efficacy of Targeted Gene Transfer in Colorectal Cancer Metastatic to Liver
Condition: Colorectal Neoplasms
Intervention: Genetic: Mx-dnG1 Retroviral Vector
4 Unknown  Gene Therapy for Chronic Granulomatous Disease
Condition: Granulomatous Disease, Chronic
Intervention: Drug: retroviral SF71-gp91phox transduced CD34+ cells
5 Completed Peripheral Blood Stem Cells Obtained From Normal Volunteers for Studying Retroviral Vector Mediated Gene Transfer Into Primitive Hematopoietic Cells and Vector Mediated Transgene Expression in Mature Hematopoietic Lineages
Condition: Immunodeficiency
Intervention:
6 Completed Gene Therapy for X-linked Chronic Granulomatous Disease (CGD) in Children
Condition: Chronic Granulomatous Disease
Intervention: Genetic: retroviral SF71-gp91phox transduced CD34+ cells
7 Active, not recruiting ADA Gene Transfer Into Hematopoietic Stem/Progenitor Cells for the Treatment of ADA-SCID
Condition: Immunologic Deficiency Syndromes
Intervention: Genetic: Gene transduced CD34+ cells
8 Completed
Has Results
MND-ADA Transduction of CD34+ Cells From Children With ADA-SCID
Condition: Severe Combined Immunodeficiency
Intervention: Biological: ADA gene transfer
9 Active, not recruiting Gene Therapy for Chronic Granulomatous Disease in Korea
Condition: Chronic Granulomatous Disease
Intervention: Drug: VM106
10 Active, not recruiting Redirected MazF‐CD4 Autologous T Cells for HIV Gene Therapy
Condition: HIV
Intervention: Genetic: Autologous CD4+ T cells genetically modified with a retroviral vector expressing the MazF endoribonuclease gene (MazF‐T), given via intravenous infusion.
11 Recruiting Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector
Condition: Severe Combined Immunodeficiency
Intervention: Biological: Gene transfer
12 Completed Gene Therapy for Gaucher's and Fabry Disease Using Viruses and Blood-Forming Cells
Condition: Gaucher's Disease
Intervention: Genetic: human glucocerebrosidase cDNA
13 Terminated Gene Transfer for HIV Using Autologous T Cells
Condition: HIV-1 Infection
Intervention: Genetic: pHIV7-shI-TAR-CCR5RZ treated CD4 cells
14 Completed Antimetabolite Induction, High-Dose Alkylating Agent Consolidation and Retroviral Transduction of the MDR1 Gene Into Peripheral Blood Progenitor Cells Followed by Intensification Therapy With Sequential Paclitaxel and Doxorubicin for Stage 4 Breast Cancer
Conditions: Breast Neoplasms;   Neoplasm Metastasis
Intervention: Genetic: peripheral blood progenitor cells carrying MDR1
15 Completed Gene Modified Allogeneic Neuroblastoma Cells For Treatment of Relapsed/Refractory Neuroblastoma
Condition: Neuroblastoma
Intervention: Drug: Interleukin-2
16 Completed Gene Therapy for ADA-SCID
Condition: Severe Combined Immunodeficiency Syndrome
Intervention: Genetic: gene transduced PBL and/or gene transduced HSC
17 Active, not recruiting Gene Therapy for X-linked Severe Combined Immunodeficiency
Condition: X-linked Severe Combined Immunodeficiency
Intervention: Other: Gene transfer
18 Completed Follow-up of Breast Cancer and Multiple Myeloma Patients Previously Enrolled in NIH Gene Therapy Studies
Condition: Gene Transfer
Intervention:
19 Completed Gene Therapy for the Treatment of Fanconi's Anemia Type C
Conditions: Fanconi's Anemia;   Pancytopenia
Intervention: Drug: Transduced CD34+ Cells
20 Completed Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)
Condition: Severe Combined Immunodeficiency
Intervention: Drug: Gene-Transduced Autologous CD34+ Stem Cells

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Study has passed its completion date and status has not been verified in more than two years.