118 studies found for:    Open Studies | niaid
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Rank Status Study
21 Recruiting Evaluating the Safety and Tolerability of Etravirine in HIV-1 Infected Infants and Children
Condition: HIV Infections
Intervention: Drug: Etravirine (ETR)
22 Recruiting Impact of Vaccination on Th2 Immunity in Infancy
Condition: Food Hypersensitivity
Interventions: Procedure: Skin prick allergen test;   Procedure: Blood draw
23 Recruiting Evaluating the Safety and Immune Response to Three Different DNA HIV Vaccines Administered With a MVA-CMDR Boost Vaccine in Healthy, HIV-Uninfected Adults
Condition: HIV Infections
Interventions: Biological: DNA Nat-B env;   Biological: DNA CON-S env;   Biological: DNA Mosaic env;   Biological: MVA-CMDR;   Biological: Placebo for DNA Nat-B env;   Biological: Placebo for DNA CON-S env;   Biological: Placebo for DNA Mosaic env;   Biological: Placebo for MVA-CMDR
24 Recruiting Randomized MMF Withdrawal in Systemic Lupus Erythematosus (SLE)
Conditions: Systemic Lupus Erythematosus;   SLE
Interventions: Drug: Mycophenolate Mofetil;   Drug: Hydroxychloroquine or Chloroquine;   Drug: Prednisone
25 Not yet recruiting Evaluating the Safety and Pharmacokinetics of VRC01, a Potent Anti-HIV Neutralizing Monoclonal Antibody, in HIV-1-Exposed Infants
Condition: HIV Infections
Intervention: Biological: VRC01
26 Recruiting Safety and Pharmacokinetics of Raltegravir in HIV-1-Exposed Newborn Infants at High Risk of Acquiring HIV-1 Infection
Condition: HIV Infections
Intervention: Drug: Raltegravir
27 Not yet recruiting Pharmacokinetics of Two Intravaginal Rings (IVRs) Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048
Condition: HIV Infections
Interventions: Drug: MK-2048A IVR (Low Dose);   Drug: MK-2048A IVR (Original Dose)
28 Recruiting Evaluating the Safety of Immediate Versus Deferred Isoniazid Preventive Therapy Among HIV-Infected Pregnant Women
Conditions: HIV Infections;   Tuberculosis
Interventions: Drug: Isoniazid (INH);   Drug: Placebo for isoniazid (INH)
29 Recruiting Bone Marrow Transplantation and High Dose Post-Transplant Cyclophosphamide for Chimerism Induction and Renal Allograft Tolerance
Condition: Kidney Transplantation
Interventions: Biological: Antithymocyte globulin (ATG);   Drug: Fludarabine;   Drug: Low dose Pre-transplant cyclophosphamide;   Radiation: Total Body Irradiation;   Drug: Acetaminophen;   Drug: Diphenhydramine;   Drug: Methylprednisolone;   Biological: Bone Marrow;   Drug: MESNA;   Drug: Mycophenolate mofetil (MMF);   Drug: Prednisone;   Drug: Filgrastim;   Drug: High dose post-transplant cyclophosphamide
30 Not yet recruiting Safety and Pharmacokinetics of Intravaginal Rings Containing Vicriviroc (MK-4176) and/or MK-2048
Condition: HIV Infections
Interventions: Device: Vicriviroc (MK-4176) Intravaginal Ring (IVR);   Device: MK-2048 IVR;   Device: MK-2048A IVR;   Device: Placebo IVR
31 Recruiting Efavirenz (EFV) in HIV-Infected and HIV/Tuberculosis (TB) Coinfected Children
Conditions: HIV Infections;   Tuberculosis
Interventions: Drug: Efavirenz (EFV);   Drug: Rifampin-containing anti-TB therapy
32 Not yet recruiting Evaluating the Safety, Tolerability, and Effect of a Human Monoclonal Antibody (VRC01) on Markers of HIV Persistence in HIV-Infected Adults Receiving Antiretroviral Therapy (ART)
Condition: HIV Infections
Interventions: Biological: VRC01;   Biological: Placebo
33 Recruiting Evaluating Safety and Effectiveness of Low-Dose Methotrexate at Reducing Inflammation in HIV-Infected Adults Taking Antiretroviral Medications
Condition: HIV Infections
Interventions: Drug: Methotrexate (MTX);   Drug: Placebo;   Dietary Supplement: Folic acid
34 Recruiting Donor-Alloantigen-Reactive Regulatory T Cell (darTregs) in Liver Transplantation
Condition: Liver Transplantation
Interventions: Biological: Anti-Thymocyte Globulin - Rabbit;   Biological: darTreg Infusion;   Drug: Everolimus;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Drug: Prednisone;   Drug: Acetaminophen;   Drug: Diphenhydramine;   Drug: Anti-Infective Prophylaxis;   Procedure: Leukapheresis;   Procedure: Blood draws;   Procedure: Liver biopsies;   Procedure: Liver transplantation
35 Recruiting Safety of and Immune Response to Dolutegravir (GSK1349572) in HIV-1 Infected Infants, Children, and Adolescents
Condition: HIV Infections
Interventions: Drug: Dolutegravir (DTG) tablet formulation;   Drug: DTG oral pediatric granules taken as suspension or granules
36 Not yet recruiting Evaluating the Safety and Immune Response to Two HIV Vaccine Regimens in Healthy, HIV-Uninfected Adults in the United States and South Africa
Condition: HIV Infections
Interventions: Biological: DNA-HIV-PT123 vaccine;   Biological: NYVAC-HIV-PT1 vaccine;   Biological: NYVAC-HIV-PT4 vaccine;   Biological: AIDSVAX B/E vaccine;   Biological: Placebo for DNA/NYVAC/AIDSVAX
37 Recruiting Anti-TSLP (AMG 157) Plus Antigen-Specific Immunotherapy for Induction of Tolerance in Individuals With Cat Allergy
Condition: Cat Allergy
Interventions: Biological: AMG 157;   Biological: Cat Immunotherapy;   Biological: Cat Immunotherapy Placebo;   Biological: AMG 157 Placebo
38 Recruiting Evaluating the Safety, Tolerance, Drug Interactions, and Effective Dosing of a Raltegravir-Containing Antiretroviral Therapy (ART) Regimen in ART-Naive Children Infected With HIV and TB
Conditions: HIV Infections;   Tuberculosis
Intervention: Drug: Raltegravir
39 Recruiting Efficacy of Ustekinumab Followed by Abatacept for the Treatment of Psoriasis Vulgaris
Condition: Psoriasis
Interventions: Biological: Ustekinumab;   Biological: Abatacept;   Procedure: Placebo for Ustekinumab;   Drug: Placebo for Abatacept
40 Recruiting Comparison of Airway Remodeling Mediators Following Experimental Human Rhinovirus Infection in Subjects With Mild to Moderate Asthma and in Healthy, Non-asthmatic Control Subjects.
Condition: Asthma
Interventions: Biological: GMP-grade HRV-39;   Procedure: Bronchoalveolar Lavage;   Drug: Methacholine Inhalation Challenge;   Procedure: Nasal Lavage;   Procedure: Nasal Scrapings;   Procedure: Bronchial Brushings;   Procedure: Lung Mucosal Biopsy;   Procedure: Allergen Skin Prick Testing;   Procedure: Venipuncture;   Procedure: Bronchoscopy;   Procedure: Spirometry

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Indicates status has not been verified in more than two years