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103 studies found for:    Open Studies | niaid
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Rank Status Study
21 Recruiting Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection Among Men and Transgender Persons Who Have Sex With Men
Condition: HIV Infections
Interventions: Biological: VRC01;   Biological: Placebo for VRC01
22 Recruiting Treg Therapy in Subclinical Inflammation in Kidney Transplantation
Conditions: Kidney Transplant;   Adult Living Donor Kidney Transplant Recipients;   Renal Transplant;   Living Kidney Donor
Interventions: Biological: Polyclonal Regulatory T Cells;   Biological: Donor-Alloantigen-Reactive Regulatory T Cells;   Drug: Everolimus;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Drug: Mycophenolic acid;   Drug: Acetaminophen;   Drug: Diphenhydramine;   Procedure: Biopsy, Kidney;   Procedure: Blood Draw;   Procedure: Leukapheresis;   Procedure: IS regimen conversion
23 Recruiting Cockroach Nasal Allergen Challenge Pilot
Conditions: Asthma;   Cockroach Hypersensitivity
Intervention: Biological: Glycerinated German Cockroach Allergenic Extract
24 Recruiting Safety and Immunogenicity of the Dengue Virus Vaccine TV005 (TetraVax-DV TV005) in Healthy Adults, Adolescents, and Children in Dhaka, Bangladesh
Condition: Dengue
Interventions: Biological: TV005 vaccine;   Biological: Placebo
25 Recruiting Safety and Therapeutic Efficacy of the VRC01 Antibody in Patients Who Initiated Antiretroviral Therapy During Early Acute HIV Infection
Condition: HIV Infections
Interventions: Biological: VRC01;   Biological: Placebo for VRC01
26 Not yet recruiting Evaluating the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-1-Infected and HIV-1-Uninfected Pregnant and Postpartum Women With Latent Tuberculosis Infection
Condition: Tuberculosis
Interventions: Drug: Rifapentine (RPT);   Drug: Isoniazid (INH);   Dietary Supplement: Pyridoxine (vitamin B6)
27 Recruiting CLAD Phenotype Specific Risk Factors and Mechanisms.
Condition: Lung Transplant
Interventions: Procedure: Blood Draw;   Procedure: Bronchoscopy
28 Recruiting Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis
Conditions: Healthy Participants;   Rheumatoid Arthritis (RA) Prevention
Interventions: Drug: Hydroxychloroquine;   Drug: HCQ Placebo
29 Recruiting Safety and Immunogenicity of the RSV D46cpΔM2-2 Vaccine in RSV-Seropositive Children and RSV-Seronegative Infants and Children
Condition: Respiratory Syncytial Virus Infections
Interventions: Biological: D46cpΔM2-2 vaccine;   Biological: Placebo
30 Recruiting Safety and Virologic Effect of a Human Monoclonal Antibody (VRC01) Administered Intravenously to Adults During Early Acute HIV Infection
Condition: HIV Infections
Interventions: Biological: VRC01;   Biological: Placebo for VRC01;   Drug: Antiretroviral therapy (ART) (regimen will vary within countries and by patient)
31 Recruiting Evaluating the Safety, Tolerability, and Pharmacokinetics of Bedaquiline and Delamanid, Alone and in Combination, For Drug-Resistant Pulmonary Tuberculosis
Conditions: Tuberculosis;   HIV Infections
Interventions: Drug: Bedaquiline;   Drug: Delamanid;   Drug: Dolutegravir
32 Recruiting Comparing the Efficacy and Safety of High-Titer Versus Low-Titer Anti-Influenza Immune Plasma for the Treatment of Severe Influenza A
Condition: Influenza A Virus Infection
Interventions: Biological: High-titer anti-influenza plasma;   Biological: Low-titer (control) anti-influenza plasma
33 Recruiting Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection in Women
Condition: HIV Infections
Interventions: Biological: VRC01;   Biological: Placebo for VRC01
34 Recruiting Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation
Conditions: Liver Transplant;   Liver Transplantation
Intervention: Procedure: Immunosuppression withdrawal
35 Recruiting Integrase and Maraviroc Intensification for Neurocognitive Dysfunction (InMIND)
Condition: HIV Infections
Interventions: Drug: Placebo for maraviroc (MVC);   Drug: Placebo for dolutegravir (DTG);   Drug: Dolutegravir (DTG);   Drug: Maraviroc (MVC)
36 Recruiting Registry for Asthma Characterization and Recruitment 2
Condition: Asthma
Intervention:
37 Recruiting Mechanisms Underlying Asthma Exacerbations Prevented and Persistent With Immune-Based Therapy
Condition: Asthma
Intervention:
38 Recruiting Effects of Inhibiting Early Inflammation in Kidney Transplant Patients
Condition: Kidney Transplant
Interventions: Biological: Infliximab;   Drug: Methylprednisolone;   Drug: Mycophenolate Mofetil;   Drug: Tacrolimus;   Biological: Thymoglobulin;   Drug: Acetaminophen;   Drug: Loratadine;   Biological: Placebo for Infliximab;   Drug: Prednisone;   Drug: Diphenhydramine
39 Recruiting Evaluating the Safety and Tolerability of Ruxolitinib in Antiretroviral-Treated HIV-Infected Adults
Condition: HIV Infections
Intervention: Drug: Ruxolitinib
40 Recruiting Donor Alloantigen Reactive Tregs (darTregs) for Calcineurin Inhibitor (CNI) Reduction
Conditions: Liver Transplant Recipient;   Living Donor (of the Respective Liver Transplant Recipient)
Interventions: Biological: darTregs;   Drug: Acetaminophen;   Drug: Diphenhydramine;   Drug: Immunosuppression (IS) Withdrawal;   Procedure: Study Mandated Procedures

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Study has passed its completion date and status has not been verified in more than two years.