122 studies found for:    Open Studies | niaid
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1 Recruiting Interferon Responses in Eczema Herpeticum
Conditions: Atopic Dermatitis;   Eczema Herpeticum;   Herpes Simplex Infections;   Eczema Vaccinatum
Intervention:
2 Not yet recruiting Safety and Immunogenicity of the Dengue Virus Vaccine TV005 (TetraVax-DV TV005) in Healthy Adults, Adolescents, and Children in Dhaka, Bangladesh
Condition: Dengue
Interventions: Biological: TV005 vaccine;   Biological: Placebo
3 Not yet recruiting Safety and Therapeutic Efficacy of the VRC01 Antibody in Patients Who Initiated Antiretroviral Therapy During Early Acute HIV Infection
Condition: HIV Infections
Interventions: Biological: VRC01;   Biological: Placebo for VRC01
4 Not yet recruiting Evaluating the Safety, Tolerability, and Immunogenicity of a Prime-Boost Regimen of HIV-1 Nef/Tat/Vif, Env pDNA Vaccine Delivered Intramuscularly With Electroporation and HIV-1 rVSV envC Vaccine in Healthy, HIV-Uninfected Adults
Condition: HIV Infections
Interventions: Biological: HIV-1 nef/tat/vif, env pDNA vaccine;   Biological: rVSV HIV envC vaccine;   Biological: Placebo
5 Not yet recruiting Evaluating the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-1-Infected and HIV-1-Uninfected Pregnant and Postpartum Women With Latent Tuberculosis Infection
Condition: Tuberculosis
Interventions: Drug: Rifapentine (RPT);   Drug: Isoniazid (INH);   Dietary Supplement: Pyridoxine (vitamin B6)
6 Not yet recruiting CLAD Phenotype Specific Risk Factors and Mechanisms.
Condition: Lung Transplant
Interventions: Procedure: Blood Draw;   Procedure: Bronchoscopy
7 Not yet recruiting Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis
Conditions: Healthy;   Rheumatoid Arthritis Prevention
Interventions: Drug: Hydroxychloroquine;   Drug: HCQ Placebo
8 Recruiting Safety and Immunogenicity of the RSV D46cpΔM2-2 Vaccine in RSV-Seropositive Children and RSV-Seronegative Infants and Children
Condition: Respiratory Syncytial Virus Infections
Interventions: Biological: D46cpΔM2-2 vaccine;   Biological: Placebo
9 Not yet recruiting Safety and Virologic Effect of a Human Monoclonal Antibody (VRC01) Administered Intravenously to Adults During Early Acute HIV Infection
Condition: HIV Infections
Interventions: Biological: VRC01;   Biological: Placebo for VRC01;   Drug: Antiretroviral therapy (ART) (regimen will vary within countries and by patient)
10 Not yet recruiting Evaluating the Safety, Tolerability, and Pharmacokinetics of Bedaquiline and Delamanid, Alone and in Combination, For Drug-Resistant Pulmonary Tuberculosis
Conditions: Tuberculosis;   HIV Infections
Interventions: Drug: Bedaquiline;   Drug: Delamanid;   Drug: Dolutegravir
11 Recruiting Comparing the Efficacy and Safety of High-Titer Versus Low-Titer Anti-Influenza Immune Plasma for the Treatment of Severe Influenza A
Condition: Influenza A Virus Infection
Interventions: Biological: High-titer anti-influenza plasma;   Biological: Low-titer (control) anti-influenza plasma
12 Not yet recruiting Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection
Condition: HIV Infections
Interventions: Biological: VRC01;   Biological: Placebo for VRC01
13 Recruiting Evaluating the Safety of and Immune Response to a Human Parainfluenza Virus Type 3 Ebola Virus Vaccine (HPIV3-EbovZ GP) in Healthy Adults
Condition: Hemorrhagic Fever, Ebola
Intervention: Biological: HPIV3-EbovZ GP Vaccine
14 Recruiting Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation
Conditions: Liver Transplant;   Liver Transplantation
Intervention: Procedure: Immunosuppression withdrawal
15 Recruiting Subcutaneous Immunotherapy for Mouse in Adults
Conditions: Asthma;   Perennial Allergic Rhinitis,
Intervention: Biological: Mouse Allergenic Extract
16 Not yet recruiting Integrase and Maraviroc Intensification for Neurocognitive Dysfunction (InMIND)
Condition: HIV Infections
Interventions: Drug: Placebo for maraviroc (MVC);   Drug: Placebo for dolutegravir (DTG);   Drug: Dolutegravir (DTG);   Drug: Maraviroc (MVC)
17 Recruiting Registry for Asthma Characterization and Recruitment 2
Condition: Asthma
Intervention:
18 Recruiting Mechanisms Underlying Asthma Exacerbations Prevented and Persistent With Immune-Based Therapy
Condition: Asthma
Intervention:
19 Recruiting Effects of Inhibiting Early Inflammation in Kidney Transplant Patients
Condition: Kidney Transplant
Interventions: Biological: Infliximab;   Drug: Methylprednisolone;   Drug: Mycophenolate Mofetil;   Drug: Tacrolimus;   Biological: Thymoglobulin;   Drug: Acetaminophen;   Drug: Loratadine;   Biological: Placebo for Infliximab;   Drug: Prednisone;   Drug: Diphenhydramine
20 Not yet recruiting Evaluating the Safety and Tolerability of Ruxolitinib in Antiretroviral-Treated HIV-Infected Adults
Condition: HIV Infections
Intervention: Drug: Ruxolitinib

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Indicates status has not been verified in more than two years