Now Available: Final Rule for FDAAA 801 and NIH Policy on Clinical Trial Reporting
476 studies found for:    Open Studies | Exclude Unknown | "neurological disorders"OR"brain tumors"OR"attention-deficit/hyperactivity disorder"OR"epilepsy"OR"chronic pain"OR"spincal cord injury"OR"stroke" | United States | Phase 1, 2, 3, 0 | Industry
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Rank Status Study
1 Recruiting Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors
Conditions: Glioblastoma Multiforme;   Glioma;   Gliosarcoma;   Malignant Brain Tumor
Interventions: Drug: Indoximod;   Drug: Temozolomide;   Drug: Bevacizumab;   Radiation: Stereotactic Radiation
2 Recruiting Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS)
Condition: Stroke
Interventions: Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin (Acetylsalicylic acid, BAY1019036);   Other: Rivaroxaban-Placebo;   Other: Aspirin-Placebo
3 Recruiting Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke
Condition: Chronic Ischemic Stroke
Interventions: Biological: SB623 Implant (2.5M);   Biological: SB623 Implant (5.0M);   Procedure: Sham surgery
4 Recruiting Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Stroke
Conditions: Acute Ischemic Stroke;   Thrombotic Disease
Interventions: Drug: DS-1040b;   Drug: placebo
5 Recruiting Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects
Conditions: Brain Cancer;   Brain Neoplasm;   Glioma;   Glioblastoma;   Gliosarcoma;   Malignant Brain Tumor;   Neoplasm, Neuroepithelial;   Neuroectodermal Tumors;   Neoplasm by Histologic Type;   Neoplasm, Nerve Tissue;   Nervous System Diseases
Interventions: Biological: DNX-2401;   Biological: pembrolizumab
6 Recruiting A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications
Condition: Epilepsy
Interventions: Drug: Lacosamide Tablet;   Drug: Lasosamide Oral Solution;   Other: Placebo Tablet;   Other: Placebo Oral Solution
7 Recruiting A Study to Investigate the Safety of the Drugs Topiramate and Levetiracetam in Treating Children Recently Diagnosed With Epilepsy
Condition: Epilepsy
Interventions: Drug: Topiramate;   Drug: Levetiracetam
8 Recruiting A Study to Investigate the Safety and Efficacy of Lacosamide Added to the Patients Current Therapy in Patients Aged 1 Month to Less Than 18 Years Old With Epilepsy Syndromes Associated With Generalized Seizures.
Condition: Epilepsy
Intervention: Drug: Lacosamide
9 Recruiting PF-06372865 in Subjects With Photosensitive Epilepsy
Condition: Reflex Epilepsy, Photosensitive
Interventions: Drug: PF-06372865;   Drug: Placebo;   Drug: Lorazepam
10 Recruiting Safety Evaluation of 3K3A-APC in Ischemic Stroke
Condition: Ischemic Stroke
Interventions: Biological: 3K3A-APC;   Drug: Placebo
11 Recruiting A Multicenter, Open-Label Proof-of-Concept Trial of Ganaxolone in Children With PCDH19 Female Pediatric Epilepsy and Other Rare Genetic Epilepsies
Condition: Epilepsy
Intervention: Drug: Ganaxolone
12 Recruiting HT-3951 vs. Placebo in Stroke Rehabilitation
Condition: Ischemic Stroke
Interventions: Drug: HT-3951;   Drug: Placebo
13 Recruiting A Study to Evaluate the Efficacy and Safety of TF0023 Spray on Subjects With Ischemic Strokes
Condition: Ischemic Stroke
Intervention: Drug: TF0023
14 Recruiting Efficacy and Safety Study of GM602 in Patients With Acute Middle Cerebral Artery Ischemic Stroke Within 18 Hours
Condition: Stroke
Interventions: Drug: GM602;   Drug: Placebo Comparator
15 Recruiting Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke
Condition: Acute Ischemic Stroke
Interventions: Drug: natalizumab;   Drug: Placebo
16 Recruiting Study to Evaluate the Safety and Efficacy of USL261 (Intranasal Midazolam) in Patients With Seizure Clusters
Condition: Epilepsy
Interventions: Drug: USL261;   Drug: Placebo
17 Recruiting Study of Nivolumab Compared to Temozolomide, Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
Condition: Brain Cancer
Interventions: Drug: Nivolumab;   Drug: Temozolomide;   Radiation: Radiotherapy
18 Recruiting Efficacy and Safety of Lacosamide as Adjunctive Therapy in Subjects ≥1 Month to <4 Years With Partial-onset Seizures
Condition: Epilepsy With Partial-onset Seizures
Interventions: Drug: Lacosamide;   Other: Placebo
19 Recruiting Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer).
Condition: Brain Neoplasms
Interventions: Drug: Nivolumab;   Drug: Temozolomide;   Radiation: Radiotherapy;   Other: Nivolumab Placebo
20 Recruiting Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)
Conditions: Stroke;   Secondary Prevention
Interventions: Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate

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