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374 studies found for:    Open Studies | "heart disease"OR"stroke"OR"cardiovascular disease" | United States | Phase 1, 2, 3, 0 | Industry
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Rank Status Study
21 Recruiting Efficacy and Safety Study of GM602 in Patients With Acute Middle Cerebral Artery Ischemic Stroke Within 18 Hours
Condition: Stroke
Interventions: Drug: GM602;   Drug: Placebo Comparator
22 Recruiting Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Stroke
Conditions: Acute Ischemic Stroke;   Thrombotic Disease
Interventions: Drug: DS-1040b;   Drug: placebo
23 Recruiting Safety and Efficacy of NA-1 in Subjects Undergoing Endovascular Thrombectomy for Stroke (ESCAPE-NA1)
Condition: Stroke, Acute
Interventions: Drug: NA-1, 2.6 mg/kg;   Drug: Placebo
24 Recruiting Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke
Condition: Acute Ischemic Stroke
Interventions: Drug: natalizumab;   Drug: Placebo
25 Recruiting HT-3951 vs. Placebo in Stroke Rehabilitation
Condition: Ischemic Stroke
Interventions: Drug: HT-3951;   Drug: Placebo
26 Recruiting A Study to Evaluate the Efficacy and Safety of TF0023 Spray on Subjects With Ischemic Strokes
Condition: Ischemic Stroke
Intervention: Drug: TF0023
27 Recruiting A Study to Evaluate the Effect of the Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Blocker, GSK2798745, on Pulmonary Gas Transfer and Respiration in Patients With Congestive Heart Failure
Condition: Heart Failure, Congestive
Interventions: Drug: GSK2798745;   Drug: Placebo
28 Recruiting Safety Evaluation of 3K3A-APC in Ischemic Stroke
Condition: Ischemic Stroke
Interventions: Biological: 3K3A-APC;   Drug: Placebo
29 Recruiting Ubiquinol as a Metabolic Resuscitator in Post-Cardiac Arrest
Condition: Cardiac Arrest
Interventions: Drug: Ubiquinol;   Dietary Supplement: Ensure
30 Recruiting Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)
Conditions: Stroke;   Secondary Prevention
Interventions: Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
31 Recruiting Apixaban Versus Warfarin for the Management of Post-operative Atrial Fibrillation
Conditions: Coronary Artery Bypass Grafting;   Postoperative Atrial Fibrilation;   Stroke;   Systemic Embolism;   Deep Venous Thrombosis
Interventions: Drug: Apixaban;   Drug: Warfarin
32 Recruiting A Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagonist (VKA) or Low Molecular Weight Heparin (LMWH) in Pediatric Subjects With Congenital or Acquired Heart Disease Requiring Anticoagulation
Condition: Thrombosis
Interventions: Drug: Apixaban;   Drug: Vitamin K Antagonist (VKA);   Drug: Low Molecular Weight Heparin (LMWH)
33 Not yet recruiting Inhaled Nitric Oxide After Out-of-Hospital Cardiac Arrest
Condition: Heart Arrest, Out-Of-Hospital
Interventions: Drug: Nitric Oxide;   Drug: Nitrogen
34 Recruiting Implant for Augmentation of Cerebral Blood Flow Trial, Effectiveness and Safety in a 24 Hour Window
Condition: Ischemic Stroke
Interventions: Device: The Ischemic Stroke System;   Device: Sham control
35 Recruiting Fontan Udenafil Exercise Longitudinal Assessment Trial
Condition: Single Ventricle Heart Disease
Interventions: Drug: Udenafil;   Drug: Placebo
36 Not yet recruiting A Extension Study of Udenafil in Adolescents
Condition: Functional Single Ventricle Heart Disease
Intervention: Drug: Udenafil
37 Recruiting Study to Assess the Safety, Tolerability and PK Response and Explore the PD Response Following 4 Weekly SC Injections of PB1046 in Subjects With Stable Heart Failure With Reduced Ejection Fraction (HFrEF)
Condition: Heart Failure
Interventions: Drug: PB1046 Injection;   Drug: Placebo Injection
38 Recruiting CardiAMP™ Heart Failure Trial
Condition: Heart Failure
Interventions: Biological: Autologous cell therapy;   Device: CardiAMP cell therapy;   Other: Sham
39 Recruiting A Trial Comparing Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Advanced Prostate Cancer and Cardiovascular Disease
Condition: Prostate Cancer
Interventions: Drug: Degarelix;   Drug: Leuprolide
40 Recruiting Caisson Transcatheter Mitral Valve Replacement (TMVR) System Early Feasibility Study
Condition: Mitral Valve Regurgitation
Intervention: Device: Caisson TMVR System

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Study has passed its completion date and status has not been verified in more than two years.