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27 studies found for:    Open Studies | "Type 1 Diabetes" | NIDDK
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Rank Status Study
1 Recruiting Immune Effects of Oral Insulin in Relatives at Risk for Type 1 Diabetes Mellitus (TN20)
Condition: Type 1 Diabetes
Interventions: Drug: 67.5 mg oral insulin crystals daily;   Drug: 500mg oral insulin crystals every other week
2 Recruiting CTLA4-Ig (Abatacept)for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At -Risk for Type 1
Conditions: Abnormal Glucose Tolerance;   Type 1 Diabetes
Interventions: Drug: CTLA4-Ig (Abatacept);   Drug: Placebo
3 Recruiting Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk"
Conditions: Autoantibody Positive;   Non-diabetic Relatives at Risk for Type 1 Diabetes;   High Risk;   Impaired Glucose Tolerance
Intervention: Drug: Teplizumab
4 Recruiting Pathway to Prevention Study
Condition: Diabetes Mellitus, Type 1
Intervention:
5 Recruiting Reducing Distress And Improving Glycemic Control In Adults With Type 1 Diabetes
Condition: Type 1 Diabetes Mellitus
Interventions: Behavioral: 'KnowIt';   Behavioral: 'OnTrack'
6 Recruiting New Onset Type 1 Diabetes: Role of Exenatide
Condition: Type 1 Diabetes
Interventions: Drug: Exenatide;   Drug: Rapid and long acting insulin;   Drug: long acting insulin + rapid acting + 1.25 mcg Exenatide
7 Recruiting Insulin-Glucose-Glucagon Network: Defining a Type 1 Diabetes Progression Index
Condition: Diabetes Mellitus, Type 1
Interventions: Procedure: Metabolic Challenge Admission;   Other: CGM home test
8 Recruiting iOmit: Reducing Intentional Insulin Misuse in Type 1 Diabetes
Conditions: Type 1 Diabetes Mellitus;   Eating Disorders
Interventions: Behavioral: Therapy with Mobile App Enhancement;   Device: Recovery Record (RR) Mobile app
9 Recruiting Effect of Canagliflozin in T1DM (Type 1 Diabetes Melitus) After Interruption of Continuous Subcutaneous Insulin Infusion
Condition: Type 1 Diabetes
Interventions: Drug: canagliflozin;   Other: basal interruption without canagliflozin
10 Recruiting Tissue-Specific Metabolic Reprogramming in Diabetic Complications
Condition: Type 1 Diabetes Mellitus
Interventions: Procedure: Euglycemic clamp (normal blood sugar clamp) for 4 hours;   Procedure: hyperglycemic clamp (elevated blood sugar to 300) for 4 hours
11 Recruiting EMERALD: Effects of Metformin on Cardiovascular Function in Adolescents With Type 1 Diabetes
Condition: Type 1 Diabetes
Interventions: Drug: Metformin;   Drug: Placebo
12 Recruiting Feasibility of a Decision Support System to Reduce Glucose Variability in Subject With T1DM
Condition: Type 1 Diabetes Mellitus
Intervention: Device: Decision Support System
13 Recruiting USS Virginia Closed-Loop Versus SAP Therapy for Hypoglycemia Reduction in T1D
Condition: Type 1 Diabetes Mellitus
Interventions: Device: DiAs with USS Virginia;   Device: Sensor-Augmented Pump Therapy (placebo)
14 Recruiting Investigation Into the Effects Upon Brain Response to Change in Cirucating Glose Levels in Diabetes Mellitus
Conditions: Type 1 Diabetes;   Hypoglycemia
Intervention:
15 Recruiting MMPPC: A Probabilistic Closed-loop Artificial Pancreas to Handle Unannounced Meals and Exercise
Condition: Type 1 Diabetes
Interventions: Device: Inpatient use of the MMPPC/DiAs system;   Device: Outpatient use of the MMPPC/DiAs system
16 Recruiting Urinary Vitamin C Loss in Diabetic Subjects
Conditions: Diabetes Type 1;   Diabetes Type 2;   Healthy Volunteers
Intervention:
17 Not yet recruiting Strengths-Based Behavioral mHealth App for Parents of Adolescents With Type 1 Diabetes-Pilot Study
Condition: Diabetes Mellitus, Type 1
Intervention: Behavioral: T1Doing Well
18 Recruiting Natural History of Autoimmune Diabetes and Its Complications
Conditions: Type 1 Diabetes;   Type 2 Diabetes;   Immunologically Mediated Type 1 Diabetes;   Anti Beta-Cell Autoantibodies;   Autoimmunity
Intervention:
19 Recruiting Physical Activity and Glycemic Control in Adolescents
Condition: Type 1 Diabetes
Interventions: Behavioral: Reinforcement for meeting targeted physical activity goals;   Other: Standard of Care
20 Recruiting A Reinforcement Approach to Improve Diabetes Management
Condition: Type 1 Diabetes
Interventions: Behavioral: Reinforcement for BG testing;   Other: Standard of care

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Study has passed its completion date and status has not been verified in more than two years.