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125 studies found for:    Open Studies | "gene therapy"
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Rank Status Study
21 Not yet recruiting Safety Study of Gene Transfer Vector to Treat alpha1-antitrypsin Deficiency
Condition: alpha1-antitrypsin Deficiency
Intervention: Genetic: AAVrh.10halpha1AT
22 Recruiting Gene Therapy for Wiskott-Aldrich Syndrome (WAS)
Condition: Wiskott-Aldrich Syndrome
Intervention: Genetic: Autologous CD34 positive cells transduced with a lentiviral vector containing human WAS gene
23 Unknown  Gene Therapy With GX-12 in Combination With HAART for the HIV-1 Infected Patients
Condition: HIV Infections
Interventions: Genetic: GX-12;   Drug: HAART
24 Recruiting WT1 TCR Gene Therapy for Leukaemia: A Phase I/II Safety and Toxicity Study
Conditions: Acute Myeloid Leukaemia;   Chronic Myeloid Leukaemia
Intervention: Genetic: WT1 TCR-transduced T cells
25 Recruiting Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)
Condition: X-linked Severe Combined Immunodeficiency
Intervention: Genetic: Single infusion of autologous CD34+ cells transduced with the self-inactivating (SIN) gammaretroviral vector pSRS11.EFS.IL2RG.pre
26 Unknown  p53 Gene Therapy for Head and Neck Malignant Tumors in Advanced Stage
Condition: Neoplasms
Interventions: Drug: chemotherapy plus p53;   Drug: chemotherapy;   Radiation: radiotherapy
27 Recruiting Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products
Conditions: Severe Combined Immunodeficiency;   Malignancy, Hematologic;   Neuroblastoma;   Neoplasm;   Mucopolysaccharidosis I
Intervention: Procedure: Venipuncture
28 Recruiting Phase 1 Trial of Interleukin 12 Gene Therapy for Locally Recurrent Prostate Cancer
Condition: Prostate Cancer
Intervention: Biological: Ad5-yCD/mutTKSR39rep-hIL12
29 Recruiting Clinical Characterization on PDE6A-related Retinitis Pigmentosa in Preparation to a Gene Therapy Trial
Condition: Retinitis Pigmentosa
Intervention:
30 Recruiting Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy
Condition: Leber's Hereditary Optic Neuropathy
Interventions: Drug: injection of scAAV2-P1ND4v2 5.00x10e9 vg (Low),;   Drug: injection of scAAV2-P1ND4v2 2.46X10e10 vg (Med);   Drug: injection of scAAV2-P1ND4v2 1.0X10e11vg (High)
31 Not yet recruiting Trial of Stereotactic Body Radiation and Gene Therapy Before Nivolumab for Metastatic Non-Small Cell Lung Carcinoma
Conditions: Lung Squamous Cell Carcinoma Stage IV;   Nonsquamous Nonsmall Cell Neoplasm of Lung
Interventions: Biological: ADV/HSV-tk;   Drug: Valacyclovir;   Radiation: SBRT;   Drug: nivolumab
32 Recruiting Gene Therapy for WAS Follow-up
Condition: Wiskott-Aldrich Syndrome
Intervention: Genetic: Autologous CD34+ cells transduced with WASP lentiviral vector
33 Recruiting Gene Therapy After Frontline Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin Lymphoma
Conditions: AIDS-related Non-Hodgkin Lymphoma;   AIDS-related Plasmablastic Lymphoma;   AIDS-related Primary Effusion Lymphoma;   HIV Infection
Interventions: Drug: busulfan;   Biological: lentivirus vector rHIV7-shI-TAR-CCR5RZ-transduced hematopoietic progenitor cells;   Other: pharmacological study;   Other: laboratory biomarker analysis
34 Recruiting Intracerebral Gene Therapy for Children With Early Onset Forms of Metachromatic Leukodystrophy
Condition: Metachromatic Leukodystrophy
Intervention: Genetic: intracerebral administration of AAVrh.10cuARSA
35 Recruiting Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis
Condition: Gene Transfer
Intervention: Biological: RS1 AAV Vector
36 Recruiting Batten CLN6 Gene Therapy
Conditions: Batten Disease;   CLN6
Intervention: Drug: scAVV9.CB.CLN6
37 Recruiting Clinical Trial Phase I for Theragene in Combination With Chemotherapy for the Locally Advanced Pancreatic Cancer
Condition: Pancreatic Cancer
Intervention: Biological: Theragene®,Ad5-yCD/mutTKSR39rep-ADP
38 Not yet recruiting P53 Gene Combined With Radio- and Chemo-therapy in Treatment of Unresectable Locally Advanced Head and Neck Cancer
Condition: Advanced Head and Neck Cancer
Interventions: Drug: rAd-p53;   Radiation: radiation;   Drug: Cisplatin
39 Recruiting Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants
Condition: Severe Combined Immunodeficiency Disease, X-linked
Interventions: Genetic: CL20-4i-EF/a-hyc-OPT;   Drug: Busulfan
40 Recruiting Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies
Condition: Vaccine
Intervention:

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Indicates status has not been verified in more than two years