108 studies found for:    Open Studies | "gene therapy"
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Rank Status Study
21 Recruiting Safety and Efficacy of Subjects With Critical Limb Ischemia
Condition: Critical Limb Ischemia
Intervention: Genetic: HGF Plasmid (AMG0001)
22 Not yet recruiting P53 Gene Combined With Radio- and Chemo-therapy in Treatment of Unresectable Locally Advanced Head and Neck Cancer
Condition: Advanced Head and Neck Cancer
Interventions: Drug: rAd-p53;   Radiation: radiation;   Drug: Cisplatin
23 Recruiting MVX-ONCO-1 in Patients With Solid Tumor
Conditions: Solid Tumor;   Cancer
Intervention: Other: Treatment
24 Recruiting Retroviral Vector Mediated Globin Gene Transfer to Correct Sickle Cell Anemia or Thalassemia
Conditions: Sickle Cell Anemia;   Thalassemia
Intervention: Genetic: Gene Therapy
25 Recruiting Gene Therapy Follow-up Protocol for People Previously Enrolled in NCI Experimental Transplantation and Immunology Branch Studies
Conditions: Lyphoma, B-Cell;   Leukemia, B-cell;   Multiple Myeloma;   Hematologic Malignancies
Intervention:
26 Recruiting Gene Therapy for Blindness Caused by Choroideremia
Condition: Choroideremia
Intervention: Drug: rAAV2.REP1
27 Recruiting Gene Therapy for B-Cell Non-Hodgkin Lymphoma Using CD19 CAR Gene Transduced T Lymphocytes
Condition: Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: Drug: Cyclophosphamide or Bendamustine;   Genetic: Dose Level -1;   Genetic: Dose Level 1;   Genetic: Dose Level 2;   Genetic: Dose Level 3
28 Recruiting Gene Therapy for Transfusion Dependent Beta-thalassemia
Condition: Beta-Thalassemia
Intervention: Genetic: Autologous hematopoietic stem cells genetically modified with GLOBE lentiviral vector encoding for the human beta-globin gene
29 Recruiting Gene Therapy and Radioactive Iodine in Treating Patients With Locally Recurrent Prostate Cancer That Did Not Respond to External-Beam Radiation Therapy
Condition: Prostate Cancer
Interventions: Biological: Ad5-CMV-NIS;   Drug: liothyronine sodium;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: laboratory biomarker analysis;   Radiation: iodine I 131
30 Recruiting AADC Gene Therapy for Parkinson's Disease
Condition: Parkinson Disease
Interventions: Genetic: Cohort1;   Genetic: Cohort2
31 Recruiting AADC Gene Therapy for Parkinson's Disease
Condition: Parkinson's Disease
Intervention: Genetic: AAV2-hAADC
32 Recruiting A Phase I Study of Systemic Gene Therapy With SGT-94 in Patients With Solid Tumors
Condition: Neoplasm
Intervention: Genetic: SGT-94
33 Recruiting Stem Cell Gene Therapy for Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Genetic: βAS3-FB vector transduced BM CD34+ cells
34 Recruiting Gene Therapy After Frontline Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin Lymphoma
Conditions: AIDS-related Diffuse Large Cell Lymphoma;   AIDS-related Diffuse Mixed Cell Lymphoma;   AIDS-related Diffuse Small Cleaved Cell Lymphoma;   AIDS-related Immunoblastic Large Cell Lymphoma;   AIDS-related Lymphoblastic Lymphoma;   AIDS-related Small Noncleaved Cell Lymphoma;   HIV Infection
Interventions: Drug: busulfan;   Biological: lentivirus vector rHIV7-shI-TAR-CCR5RZ-transduced hematopoietic progenitor cells;   Other: pharmacological study;   Other: laboratory biomarker analysis
35 Unknown  A Phase I Gene Therapy Study of FP253/Fludarabine for Prostate Cancer
Condition: Prostate Cancer
Intervention: Biological: Gene Directed Enzyme Prodrug Therapy, FP253/Fludarabine
36 Recruiting Intracerebral Gene Therapy for Children With Early Onset Forms of Metachromatic Leukodystrophy
Condition: Metachromatic Leukodystrophy
Intervention: Genetic: intracerebral administration of AAVrh.10cuARSA
37 Unknown  Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit Melanoma
Conditions: Malignant Melanoma;   Neoplasm Metastasis
Intervention: Genetic: investigational drug INGN 241
38 Not yet recruiting Safety and Efficacy Study of Gene Therapy Drug (Neovasculgen) to Treat Secondary Raynaud's Phenomenon
Condition: Secondary Raynaud's Phenomenon
Intervention: Drug: Neovasculgen
39 Not yet recruiting Phase 3 Gene Therapy for Painful Diabetic Neuropathy
Conditions: Painful Diabetic Neuropathy;   Diabetic Neuropathy, Painful
Interventions: Biological: VM202;   Biological: placebo
40 Recruiting A Study Evaluating the Safety and Efficacy of the LentiGlobin® BB305 Drug Product in Beta-Thalassemia Major Subjects
Condition: Beta-thalassemia Major
Intervention: Genetic: LentiGlobin® BB305 Drug Product

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Indicates status has not been verified in more than two years