1003 studies found for:    Open Studies | "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Recruiting Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT
Conditions: Acute Myeloid Leukemia;   Acute Lymphoid Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Chronic Lymphocytic Leukemia;   Immune System Diseases
Interventions: Drug: Cyclophosphamide;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Procedure: Allogeneic hematopoietic stem cell transplantation
2 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
3 Not yet recruiting A Study of Vadastuximab Talirine Given Prior to or After Allogeneic Hematopoietic Stem Cell Transplant in AML Patients
Condition: Acute Myeloid Leukemia
Interventions: Drug: Fludarabine;   Drug: Melphalan;   Drug: Methotrexate;   Drug: Tacrolimus;   Drug: vadastuximab talirine
4 Not yet recruiting Ublituximab + TGR-1202 Compared to Obinutuzumab + Chlorambucil in Patients With Chronic Lymphocytic Leukemia
Condition: Chronic Lymphocytic Leukemia
Interventions: Biological: Obinutuzumab;   Biological: Ublituximab;   Drug: TGR-1202;   Drug: Chlorambucil
5 Not yet recruiting IRX-2 Regimen in Patients With Newly Diagnosed Stage III or IVA Squamous Cell Carcinoma of the Oral Cavity
Condition: Squamous Cell Carcinoma of the Oral Cavity
Interventions: Biological: IRX-2;   Drug: Cyclophosphamide;   Drug: Indomethacin;   Dietary Supplement: Zinc-containing multivitamin;   Drug: Omeprazole
6 Recruiting Temozolomide in Preventing Brain Metastases in Small Cell Lung Cancer
Conditions: Small Cell Lung Cancer;   Metastatic Carcinoma
Interventions: Drug: temozolomide;   Radiation: prophylaxis cranial radiotherapy
7 Recruiting Chemo Sensitization Before Hematopoietic Stem Cell Transplantation in Patients With Acute Leukemia in Complete Remission
Conditions: Acute Myeloid Leukemia;   Acute Lymphoid Leukemia
Interventions: Drug: Busulfan;   Drug: Cyclophosphamide;   Drug: CXCR4 Antagonist;   Procedure: Hematopoietic Stem Cell Transplantation
8 Not yet recruiting Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma
Condition: Neuroblastoma
Interventions: Drug: Thiotepa;   Drug: Cyclophosphamide;   Drug: Melphalan;   Drug: Etoposide;   Drug: Carboplatin;   Biological: Autologous Stem Cell Infusion;   Biological: Granulocyte colony stimulating factor
9 Not yet recruiting High-Dose Weekly Carfilzomib Plus Cyclophosphamide and Dexamethasone in the Treatment of Relapsed Multiple Myeloma
Condition: Multiple Myeloma
Interventions: Drug: Carfilzomib;   Drug: Cyclophosphamide;   Drug: Dexamethasone
10 Recruiting Safety and Efficacy of MPDL3280A in Combination With Either Obinutuzumab Plus Bendamustine or Obinutuzumab Plus CHOP in Patients With Follicular Lymphoma or Diffuse Large B-Cell Lymphoma
Condition: Lymphoma, Large B-Cell, Diffuse, Lymphoma, Follicular
Interventions: Drug: Bendamustine;   Drug: Cyclophosphamide;   Drug: Doxorubicin;   Drug: MPDL3280A;   Drug: Obinutuzumab;   Drug: Prednisone;   Drug: Vincristine
11 Not yet recruiting Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma
Condition: Pineoblastoma
Interventions: Drug: Temozolomide;   Drug: Irinotecan;   Drug: Dasatinib;   Drug: Rapamycin
12 Not yet recruiting Cisplatin and Etoposide or Temozolomide and Capecitabine in Treating Patients With Neuroendocrine Carcinoma of the Gastrointestinal Tract or Pancreas That Is Metastatic or Cannot Be Removed by Surgery
Conditions: Colorectal Large Cell Neuroendocrine Carcinoma;   Esophageal Large Cell Neuroendocrine Carcinoma;   Gallbladder Large Cell Neuroendocrine Carcinoma;   Gastric Large Cell Neuroendocrine Carcinoma;   Pancreatic Large Cell Neuroendocrine Carcinoma;   Small Intestinal Large Cell Neuroendocrine Carcinoma
Interventions: Drug: Capecitabine;   Drug: Cisplatin;   Drug: Etoposide;   Other: Laboratory Biomarker Analysis;   Drug: Temozolomide
13 Recruiting Safety and Efficacy Study of CNOP Chemotherapy in Diffuse Large B Cell Lymphoma
Condition: Diffuse Large B Cell Lymphoma
Interventions: Drug: Cyclophosphamide;   Drug: Vincristine;   Drug: Prednisone
14 Recruiting A Dose-Finding Study of Folotyn® (Pralatrexate Injection) Plus CHOP With Peripheral T-Cell Lymphoma (PTCL)
Condition: Peripheral T-Cell Lymphoma (PTCL)
Intervention: Drug: Pralatrexate Injection
15 Recruiting Study of Rituximab and Bendamustine With or Without Brentuximab Vedotin for CD30 Positive Diffuse Large B-cell Lymphoma
Conditions: Diffuse Large B-cell Lymphoma Refractory;   Follicular B-cell Non-Hodgkin's Lymphoma
Interventions: Drug: Brentuximab Vedotin;   Drug: Rituximab;   Drug: Bendamustine
16 Not yet recruiting Folate Receptor Alpha Peptide Vaccine With GM-CSF in Patients With Triple Negative Breast Cancer
Condition: Breast Cancer
Interventions: Biological: Low dose FRα vaccine;   Drug: Cyclophosphamide;   Biological: High dose FRα vaccine
17 Recruiting Treatment Study of Denintuzumab Mafodotin (SGN-CD19A) Plus RICE Versus RICE Alone for Diffuse Large B-Cell Lymphoma
Conditions: Lymphoma, B-cell;   Lymphoma, Large B-Cell, Diffuse;   Lymphoma, Follicular, Grade 3b;   Follicular Lymphoma, Grade 3b
Interventions: Drug: denintuzumab mafodotin;   Drug: rituximab;   Drug: ifosfamide;   Drug: carboplatin;   Drug: etoposide
18 Not yet recruiting Analysis of Oral Mucositis in Patient's Undergoing Melphalan Conditioning and Autologous Stem Cell Transplant
Conditions: Mucositis;   Multiple Myeloma;   Amyloidosis;   Oral Mucositis
Interventions: Other: Melphalan kinetic study;   Genetic: Oral bacterial study;   Genetic: Gene expression study
19 Not yet recruiting Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype
Condition: Lymphoma
Interventions: Drug: Lenalidomide;   Drug: Vorinostat;   Drug: Gemcitabine;   Drug: Busulfan;   Drug: Melphalan;   Drug: Rituximab;   Drug: Dexamethasone;   Drug: Caphosol;   Drug: Glutamine;   Drug: Pyridoxine;   Drug: Enoxaparin;   Procedure: Stem Cell Transplant;   Drug: Palifermin
20 Recruiting Study of MLN9708 Plus Oral Dexamethasone or Plus Oral Cyclophosphamide and Dexamethasone or Plus Bendamustine and Dexamethasone or Plus Oral Thalidomide and Dexamethasone Followed by Maintenance With MLN9708 in Newly Diagnosed Elderly Multiple Myeloma Patients
Condition: Multiple Myeloma
Interventions: Drug: MLN9708;   Drug: Dexamethasone;   Drug: Cyclophosphamide;   Drug: Bendamustine;   Drug: Thalidomide

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Indicates status has not been verified in more than two years