1010 studies found for:    Open Studies | "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Recruiting Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT
Conditions: Acute Myeloid Leukemia;   Acute Lymphoid Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Chronic Lymphocytic Leukemia;   Immune System Diseases
Interventions: Drug: Cyclophosphamide;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Procedure: Allogeneic hematopoietic stem cell transplantation
2 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
3 Not yet recruiting CEOP/IVE/GDP Compared With CEOP as the First-line Therapy for Newly Diagnosed Adult Patients With PTCL
Conditions: Peripheral T-Cell Lymphoma;   Angioimmunoblastic T Cell Lymphoma;   ALK-negative Anaplastic Large Cell Lymphoma;   Enteropathy Associated T Cell Lymphoma;   Subcutaneous Panniculitis Like T Cell Lymphoma;   Acute Adult T-Cell Leukemia/Lymphoma
Interventions: Drug: CEOP/IVE/GDP chemotherapy regimen;   Drug: CEOP chemotherapy regimen for 8 cycles
4 Recruiting The Research of Standard Diagnosis and Treatment for HSPN in Children
Condition: Henoch-Schoenlein Purpura Nephritis
Interventions: Drug: Prednisone;   Drug: Cyclophosphamide(CTX);   Drug: Mycophenolate mofetil(MMF);   Drug: Leflunomide(LEF);   Drug: Angiotensin-converting enzyme inhibitor(ACEI);   Drug: Methylprednisolone
5 Recruiting High-dose Chemotherapy and ASCT or Consolidating Conventional Chemotherapy in Primary CNS Lymphoma
Condition: Diffuse Large B-cell-lymphoma
Interventions: Drug: Arm A (Fortecortin®-ETOPOPHOS®-IFO-cell®-CARBO-cell®);   Drug: Arm B (TEPADINA®-CARMUBRIS®-Busilvex®)
6 Recruiting Metformin in Combination With Standard Induction Therapy for Large B-cell Lymphoma (DLBCL)
Condition: Diffuse Large B-Cell Lymphoma
Interventions: Drug: Metformin;   Drug: Rituximab;   Drug: Cyclophosphamide;   Drug: Doxorubicin;   Drug: Vincristine;   Drug: Prednisone;   Drug: pegfilgrastim
7 Not yet recruiting Trial of Immune Reconstitution With Activated T-Cells Following Lymphodepleting Chemotherapy in Patients With Chronic Lymphocytic Leukemia (CLL)
Conditions: Leukemia;   Chronic Lymphocytic Leukemia
Interventions: Drug: Rituximab;   Drug: Cyclophosphamide;   Drug: Fludarabine monophosphate;   Drug: Bendamustine;   Biological: Activated T-Cell Infusion;   Drug: Lenalidomide;   Behavioral: Phone Calls
8 Not yet recruiting Radiation Therapy With Temozolomide and Pembrolizumab in Treating Patients With Newly Diagnosed Glioblastoma
Condition: Adult Glioblastoma
Interventions: Other: Laboratory Biomarker Analysis;   Biological: Pembrolizumab;   Radiation: Radiation Therapy;   Drug: Temozolomide
9 Not yet recruiting A Phase I/II Study of Lenalidomide and Obinutuzumab With CHOP for Diffuse Large B Cell Lymphoma
Condition: Lymphoma
Interventions: Drug: Lenalidomide;   Drug: Obinutuzumab;   Drug: Cyclophosphamide;   Drug: Doxorubicin;   Drug: Vincristine;   Drug: Prednisone
10 Not yet recruiting Safety and Efficacy of an Immunoablative Nonmyeloablative Conditioning Protocol for Autologous Bone Marrow Transplantation (BMT) in Patients With Multiple Sclerosis (MS)
Condition: Multiple Sclerosis
Interventions: Procedure: Autologous bone marrow transplantation;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Alemtuzumab
11 Not yet recruiting CD19+ CAR T Cells for Lymphoid Malignancies
Conditions: Leukemia;   Lymphoma
Interventions: Drug: Fludarabine monophosphate;   Drug: Cyclophosphamide;   Procedure: T Cell Infusion
12 Not yet recruiting Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis
Conditions: Acute Myeloid Leukemia in Remission;   Primary Myelofibrosis;   Primary Myelofibrosis, Prefibrotic Stage;   Secondary Acute Myeloid Leukemia;   Secondary Myelofibrosis
Interventions: Procedure: Allogeneic Bone Marrow Transplantation;   Procedure: Allogeneic Hematopoietic Stem Cell Transplantation;   Drug: Fludarabine Phosphate;   Other: Laboratory Biomarker Analysis;   Drug: Melphalan;   Procedure: Peripheral Blood Stem Cell Transplantation;   Other: Pharmacological Study;   Drug: Ruxolitinib Phosphate;   Drug: Sirolimus;   Drug: Tacrolimus
13 Recruiting A Pharmacokinetics/Dynamics Ib Study of F-627 in Women With Breast Cancer Receiving Myelotoxic Chemotherapy
Condition: Neutropenia
Interventions: Biological: F-627;   Drug: TAC regimen
14 Recruiting A Phase II, Dose-finding Study of F-627 in Patients With Breast Cancer Receiving Myelotoxic Chemotherapy.
Condition: Neutropenia
Interventions: Biological: F-627;   Biological: Filgrastim;   Drug: Epirubicin and Cyclophosphamide
15 Recruiting Supra-early Post-Surgery Chemotherapy in the Treatment on GBM Patients
Condition: Glioblastoma
Interventions: Drug: supra-early TEMODAL® chemotherapy;   Drug: standard TEMODAL® chemotherapy;   Radiation: Radiotherapy 60Gy
16 Not yet recruiting Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma
Conditions: Acute Lymphoblastic Leukemia;   Lymphoma, Non-Hodgkin's;   Leukemia, T-Cell;   Leukemia, B-Cell
Interventions: Drug: Dexamethasone;   Drug: Panobinostat;   Drug: Liposomal vincristine;   Drug: Mitoxantrone;   Drug: Peg-asparaginase;   Drug: Bortezomib;   Drug: Intrathecal Triples;   Drug: High-dose methotrexate;   Drug: 6-Mercaptopurine;   Drug: High-dose cytarabine;   Drug: Nelarabine;   Drug: Cyclophosphamide;   Drug: Etoposide;   Drug: Clofarabine
17 Recruiting Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma
Conditions: Solid Tumor;   Osteosarcoma
Intervention: Drug: Sirolimus combined with CP, MT and ZA
18 Recruiting SAR650984 Combined to CyBorD in Newly Diagnosed Multiple Myeloma (MM) Non Eligible for Transplant
Condition: Haematological Malignancy
Interventions: Drug: SAR650984;   Drug: bortezomib;   Drug: cyclophosphamide;   Drug: dexamethasone
19 Recruiting Carfilzomib in Combination With Cyclophosphamide and Etoposide for Children
Conditions: Relapsed Solid Tumors;   Refractory Solid Tumors;   Leukemias
Interventions: Drug: Carfilzomib;   Drug: Cyclophosphamide;   Drug: Etoposide
20 Not yet recruiting Romidepsin Maintenance After Allogeneic Stem Cell Transplantation
Conditions: Cutaneous T-cell Lymphoma;   T-Prolymphocytic Leukemia;   T-Large Granulocytic Leukemia;   T-Lymphoblastic Leukemia/Lymphoma;   Peripheral T-Cell Lymphoma
Interventions: Drug: Romidepsin;   Drug: Busulfan;   Drug: Fludarabine;   Procedure: Stem Cell Transplant

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Indicates status has not been verified in more than two years