1185 studies found for:    Open Studies | "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Recruiting Denintuzumab Mafodotin (SGN-CD19A) Combined With RCHOP or RCHP Versus RCHOP Alone in Diffuse Large B-Cell Lymphoma or Follicular Lymphoma
Conditions: Diffuse, Large B-Cell, Lymphoma;   Follicular Lymphoma, Grade 3b;   Transformed Lymphoma / DLBCL
Interventions: Drug: denintuzumab mafodotin;   Drug: rituximab;   Drug: cyclophosphamide;   Drug: doxorubicin;   Drug: vincristine;   Drug: prednisone
2 Recruiting PTCy and Ruxolitinib GVHD Prophylaxis in Myelofibrosis
Conditions: Primary Myelofibrosis;   Myeloproliferative Disorders
Interventions: Procedure: Allogeneic hematopoietic stem cell transplantation;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Cyclophosphamide;   Drug: Ruxolitinib
3 Recruiting GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia
Conditions: Leukemia, Acute Lymphoblastic;   Acute Myeloid Leukemia;   Mixed-Lineage Acute Leukemias
Interventions: Procedure: Allogeneic stem cell transplantation;   Drug: Fludarabine monophosphate;   Drug: Busulfan;   Drug: Bendamustine
4 Recruiting Trial of GVHD Prophylasxis With PTCy or Thymoglobulin in Unrelated SCT
Conditions: Leukemia, Chronic Myeloid;   Myelodysplastic Syndromes;   Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Interventions: Procedure: Unrelated allogeneic stem cell transplantation;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Drug: Cyclophosphamide;   Drug: Thymoglobulin
5 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
6 Not yet recruiting Disulfiram in Recurrent Glioblastoma
Conditions: Glioma;   Glioblastoma
Interventions: Drug: Disulfiram;   Dietary Supplement: Copper;   Drug: Alkylating Agents
7 Recruiting Chidamide Combined With Cyclophosphamide、Prednisone、Thalidomide in Treatment of Fragile Patients With Relapse/Refratory Peripheral T Cell Lymphoma
Condition: Relapse/Refratory Peripheral T Cell Lymphoma
Intervention: Drug: C-CPT
8 Recruiting Trial of Adjuvant Chemotherapy in Breast Cancer Patients With Pathological Partial Response to Neoadjuvant Chemotherapy
Conditions: Invasive Ductal Breast Cancer;   Tubular Breast Cancer;   Mucinous Breast Cancer;   Inflammatory Breast Cancer
Interventions: Drug: Paclitaxel;   Drug: Cisplatin;   Drug: Epirubicin;   Drug: Cyclophosphamide;   Drug: 5-fluoruracil
9 Not yet recruiting Hyper-CVAD Regimen in Sequential Combination With Blinatumomab as Frontline Therapy for Adults With B-Cell Lineage Acute Lymphocytic Leukemia
Conditions: Leukemia;   Acute Lymphoblastic Leukemia
Interventions: Drug: Cyclophosphamide;   Drug: MESNA;   Drug: Dexamethasone;   Drug: Ofatumumab;   Drug: Methotrexate;   Drug: Doxorubicin;   Drug: Vincristine;   Drug: Cytarabine;   Drug: Rituximab;   Drug: Pegfilgrastim;   Drug: G-CSF;   Drug: Leucovorin;   Drug: Blinatumomab;   Drug: 6-Mercaptopurine;   Drug: Prednisone;   Behavioral: Phone Calls
10 Recruiting Anti-GPC3 CAR T for Recurrent or Refractory Lung Squamous Cell Carcinoma
Condition: Lung Squamous Cell Carcinoma
Interventions: Genetic: CAR-GPC3 T Cells;   Drug: Fludarabine;   Drug: Cyclophosphamide
11 Not yet recruiting Cyclophosphamide Versus Anti-thymocyte Globulin for GVHD Prophylaxis After RIC Allo-SCT
Condition: Graft vs Host Disease
Interventions: Drug: Cyclophosphamide;   Drug: Anti-Thymocyte Globulin;   Drug: Conditioning regimen
12 Not yet recruiting ACTolog in Patients With Solid Cancers
Conditions: Cancer;   Solid Tumor
Interventions: Drug: Fludarabine;   Drug: Cyclophosphamide;   Biological: IMA101 T-cell product;   Biological: Recombinant human interleukin-2
13 Not yet recruiting Study Of Ruxolitinib (INCB018424) With Preoperative Chemotherapy For Triple Negative Inflammatory Breast Cancer
Condition: Inflammatory Breast Cancer (IBC).
Interventions: Drug: Ruxolitinib;   Drug: Paclitaxel;   Drug: Doxorubicin;   Drug: Cyclophosphamide
14 Not yet recruiting A Phase II Study of Using Panitumumab/Carboplatin/Paclitaxel (PaCT) Followed by Anthracycline-Containing Regimen (AC) for New Triple-Negative Inflammatory Breast Cancer (TN-IBC)
Condition: Malignant Neoplasm of Breast
Interventions: Procedure: Breast Core Biopsy;   Drug: Paclitaxel;   Drug: Carboplatin;   Drug: Panitumumab;   Drug: Doxorubicin;   Drug: Cyclophosphamide;   Procedure: Mammogram;   Procedure: Ultrasound;   Other: Follow Up
15 Recruiting HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors
Conditions: Medulloblastoma;   Central Nervous System Embryonal Tumors
Interventions: Drug: Induction;   Drug: Single Cycle Intensive Chemotherapy;   Drug: Tandem 3 Cycle Intensive Chemotherapy
16 Not yet recruiting Safety and Efficacy Study of GL-0817 (With Cyclophosphamide) for the Prevention of Recurrence of Squamous Cell Carcinoma of the Oral Cavity
Condition: Squamous Cell Carcinoma of the Oral Cavity
Interventions: Drug: GL-0817;   Drug: Hiltonol;   Drug: Sargramostim;   Drug: cyclophosphamide;   Drug: Placebo
17 Recruiting Cinobufacini Tablets Combined With Chemotherapeutic Protocol in Treatment of Diffuse Large B Cell Lymphoma
Condition: Diffuse, Large B-Cell, Lymphoma
Interventions: Drug: vindesine;   Drug: cyclophosphamide;   Drug: pirarubicin;   Drug: prednisone tablets;   Drug: Cinobufacini Tablets
18 Not yet recruiting Phase 1 Two Part Dose Escalation Trial of RRx-001 + Radiation + Temozolomide and RRx-001 + Temozolomide Post-RT In Newly Diagnosed Glioblastoma and Anaplastic Gliomas
Conditions: Glioblastoma;   Oligodendroglioma;   Anaplastic Oligodendroglioma
Interventions: Drug: RRx-001 dose escalation with TMZ + RT;   Radiation: Radiation;   Drug: Fixed dose Temozolomide (75 mg/m2);   Drug: Fixed RRx-001 weekly;   Drug: Staged TMZ and RRx-001 escalation in maintenance stage;   Drug: TMZ Maintenance
19 Recruiting Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated (RB SFCE 2009)
Condition: Retinoblastoma
Interventions: Other: Observation;   Drug: Etoposide;   Drug: Vincristine;   Radiation: Orbital irradiation;   Drug: Carboplatin;   Drug: Cyclophosphamide;   Drug: Thiotepa;   Procedure: Cytapheresis;   Procedure: Peripheral bood stem cell transplantation
20 Not yet recruiting Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors
Conditions: NY-ESO-1 Expressing Solid Tumors in HLA-A2 Positive Patients;   Synovial Sarcoma;   Melanoma;   Esophageal Cancer;   Ovarian Cancer;   Lung Cancer;   Bladder Cancer;   Liver Cancer
Interventions: Drug: Cyclophosphamide;   Biological: TBI-1301

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Indicates status has not been verified in more than two years