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1047 studies found for:    Open Studies | "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Not yet recruiting The Efficacy and Safety of R-EPOCH and R-CHOP Regimen for Patients With AIDS Associated CD20+ Diffuse Large B Lymphoma
Condition: To Evaluate the Efficacy and Safety of R-EPOCH and R-CHOP Regimen for Patients With AIDS Associated CD20+ Diffuse Large B Lymphoma
Interventions: Drug: R-EPOCH;   Drug: R-CHOP
2 Recruiting Disulfiram in Recurrent Glioblastoma
Conditions: Glioma;   Glioblastoma
Interventions: Drug: Disulfiram;   Dietary Supplement: Copper;   Drug: Alkylating Agents
3 Recruiting PTCy and Ruxolitinib GVHD Prophylaxis in Myelofibrosis
Conditions: Primary Myelofibrosis;   Myeloproliferative Disorders
Interventions: Procedure: Allogeneic hematopoietic stem cell transplantation;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Cyclophosphamide;   Drug: Ruxolitinib
4 Recruiting GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia
Conditions: Leukemia, Acute Lymphoblastic;   Acute Myeloid Leukemia;   Mixed-Lineage Acute Leukemias
Interventions: Procedure: Allogeneic stem cell transplantation;   Drug: Fludarabine monophosphate;   Drug: Busulfan;   Drug: Bendamustine
5 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
6 Recruiting Denintuzumab Mafodotin (SGN-CD19A) Combined With RCHOP or RCHP Versus RCHOP Alone in Diffuse Large B-Cell Lymphoma or Follicular Lymphoma
Conditions: Diffuse, Large B-Cell, Lymphoma;   Follicular Lymphoma, Grade 3b;   Transformed Lymphoma / DLBCL
Interventions: Drug: denintuzumab mafodotin;   Drug: rituximab;   Drug: cyclophosphamide;   Drug: doxorubicin;   Drug: vincristine;   Drug: prednisone
7 Recruiting Trial of GVHD Prophylasxis With PTCy or Thymoglobulin in Unrelated SCT
Conditions: Leukemia, Chronic Myeloid;   Myelodysplastic Syndromes;   Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Interventions: Procedure: Unrelated allogeneic stem cell transplantation;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Drug: Cyclophosphamide;   Drug: Thymoglobulin
8 Not yet recruiting A Study Assessing BGB-290 With Radiation and/or Temozolomide (TMZ) in Subjects With Newly Diagnosed or Recurrent Glioblastoma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: BGB-290;   Drug: TMZ;   Radiation: Radiation
9 Not yet recruiting Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastoma
Conditions: Glioblastoma;   Gliosarcoma
Interventions: Radiation: Dose-Escalated Radiation Therapy;   Procedure: Spectroscopic Magnetic Resonance Imaging;   Drug: Temozolomide
10 Not yet recruiting Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery
Conditions: Metastatic Leiomyosarcoma;   Metastatic Liposarcoma
Interventions: Drug: Avelumab;   Other: Laboratory Biomarker Analysis;   Drug: Trabectedin
11 Not yet recruiting Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression
Conditions: Glioma;   Glioblastoma;   Glioblastoma Multiforme;   GBM;   Brain Cancer
Intervention: Drug: VAL-083 (Dianhydrogalactitol)
12 Not yet recruiting A Phase I Clinical Study for Evaluating the Safety and Efficacy of MASCT-I in Patients With Advanced Solid Tumors
Conditions: Advanced Cancer;   Bladder Cancer;   Soft Tissue Sarcoma
Interventions: Biological: MASCT-I;   Drug: Ifosfamide
13 Not yet recruiting Study of Laser Interstitial Thermal Therapy (LITT) in Recurrent Glioblastoma
Conditions: Malignant Neoplasms of Eye Brain and Other Parts of Central Nervous System;   Glioblastoma;   Anaplastic Astrocytoma
Interventions: Procedure: Laser Interstitial Thermal Therapy;   Drug: Lomustine;   Behavioral: Quality of Life Questionnaires;   Device: The NeuroBlate System
14 Recruiting Geriatric Assessmen of Elderly "Unsuited" Patients Receiving Trabectedin in First Line Treatment For Advanced Soft Tissue Sarcomas (STS)
Conditions: Advanced Soft-tissue Sarcoma;   Metastatic Soft-tissue Sarcoma
Intervention: Other: No Intervention
15 Recruiting Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)
Condition: Glioblastoma
Interventions: Drug: Pembrolizumab;   Biological: HSPPC-96;   Drug: Temozolomide;   Other: Placebo;   Radiation: radiation treatment
16 Not yet recruiting Phase II/III Trial of CCRT With or Without JP001 for Newly Diagnosed GBM
Condition: Glioblastoma
Interventions: Radiation: CCRT;   Drug: Temozolomide;   Drug: Siroquine
17 Not yet recruiting Trial On Trabectedin In The Treatment Of Advanced Uterine And Ovarian Carcinosarcoma (CS)_MITO 26
Conditions: Carcinosarcoma, Ovarian;   Carcinosarcomas Uterine
Intervention: Drug: Trabectedin
18 Not yet recruiting PVSRIPO With/Without Lomustine
Condition: Malignant Glioma
Interventions: Biological: PVSRIPO;   Drug: Lomustine
19 Recruiting INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Condition: Glioblastoma
Interventions: Drug: Temozolomide;   Drug: Neratinib;   Drug: CC-115;   Drug: Abemaciclib
20 Not yet recruiting Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas
Condition: High Grade Glioma
Interventions: Procedure: LITT;   Radiation: Radiation therapy;   Drug: Temozolomide

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Study has passed its completion date and status has not been verified in more than two years.