1008 studies found for:    Open Studies | "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Recruiting Trial of GVHD Prophylasxis With PTCy or Thymoglobulin in Unrelated SCT
Conditions: Leukemia, Chronic Myeloid;   Myelodysplastic Syndromes;   Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Interventions: Procedure: Unrelated allogeneic stem cell transplantation;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Drug: Cyclophosphamide;   Drug: Thymoglobulin
2 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
3 Recruiting Radiation Therapy and Combination Chemotherapy for Medulloblastoma
Condition: Medulloblastoma
Interventions: Drug: Temozolomide;   Radiation: Craniospinal Radiation
4 Recruiting Percutaneous Hepatic Perfusion vs Best Alternative Care in Patients With Hepatic-dominant Ocular Melanoma
Condition: Melanoma, Ocular
Interventions: Procedure: Melphalan;   Procedure: TACE;   Drug: Dacarbazine;   Drug: Ipilimumab;   Drug: Pembrolizumab
5 Not yet recruiting Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease
Condition: Sickle Cell Disease
Interventions: Drug: Alemtuzumab;   Drug: Cyclophosphamide;   Drug: Mycophenolate mofetil;   Drug: Sirolimus;   Drug: Fludarabine;   Radiation: Total body irradiation;   Procedure: Hematopoietic stem cell transplant
6 Not yet recruiting A Study of Olaratumab Alone and in Combination With Standard Chemotherapies in Children With Cancer
Condition: Neoplasm Metastasis
Interventions: Drug: Olaratumab;   Drug: Doxorubicin;   Drug: Vincristine;   Drug: Irinotecan;   Drug: Ifosfamide
7 Recruiting Trial Comparing Trabectedin to the Best Supportive Care in Patients With Sarcoma
Condition: Soft Tissue Sarcoma
Interventions: Drug: Trabectedin;   Drug: Dexamethasone
8 Recruiting Nimotuzumab in Combination With Radio-chemotherapy for the Treatment of Brainstem Tumor in Children
Condition: Childhood Brain Stem Neoplasm
Interventions: Drug: Nimotuzumab;   Drug: Temozolomide
9 Not yet recruiting Study of Ibrutinib in Combination With Rituximab-CHOP in Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma
Condition: Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma
Interventions: Drug: Ibrutinib;   Drug: Rituximab;   Drug: Cyclophosphamide;   Drug: Doxorubicin;   Drug: vincristine;   Drug: Prednisolone
10 Recruiting ALL SCTped FORUM - Pharmacogenomic Study (add-on Study)
Condition: Acute Lymphoblastic Leukemia
Interventions: Genetic: Pharmacogenomics;   Other: Busulfan plasma level measurements
11 Recruiting Autologous Hematopoietic Stem Cell Transplantation as Adjuvant Treatment for Triple Negative Breast Cancer Patients
Conditions: Triple-Negative Invasive Breast Carcinoma;   Recurrence
Interventions: Drug: Carmustine;   Drug: Cyclophosphamide;   Drug: Carboplatin;   Procedure: Autologous Hematopoietic Stem Cell Transplantation
12 Not yet recruiting Pharmacokinetic Study of Propylene Glycol-Free Melphalan HCl for Myeloablative Conditioning in Multiple Myeloma Patients Undergoing Autologous Transplantation
Condition: Multiple Myeloma
Intervention: Drug: Melphalan HCl for injection (propylene glycol free)
13 Not yet recruiting Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer).
Condition: Brain Neoplasms
Interventions: Drug: Nivolumab;   Drug: Temozolomide;   Radiation: Radiotherapy;   Other: Nivolumab Placebo
14 Recruiting Phase II Trial GA101 Inbrutinib B CLL
Condition: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: Drug: GA101;   Drug: Ibrutinib;   Drug: Cyclophosphamide;   Drug: Fludarabine
15 Recruiting Study of Capecitabine and Cyclophosphamide Administered as a Single Pill in Patients With Advanced Breast Cancer
Condition: Breast Cancer Metastatic
Intervention: Drug: Fixed-dose combination of capecitabine and cyclophosphamide SAR439281
16 Recruiting Trial of Hypofractionated Intensity Modulated Radiation Therapy With Temozolomide and Granulocyte-macrophage Colony-stimulating Factor for Patients With Newly Diagnosed Glioblastoma Multiforme
Condition: Glioblastoma Multiforme
Interventions: Radiation: Hypofractionated IMRT;   Biological: Granulocyte-macrophage Colony-stimulating Factor;   Drug: Temozolomide
17 Not yet recruiting Phase II Autologous Cytomegalovirus (CMV)-Specific Cytotoxic T Cells for Glioblastoma (GBM) Patients
Conditions: Glioblastoma;   Gliosarcoma
Interventions: Drug: Temozolomide;   Biological: T Cell Infusion;   Procedure: Surgery;   Behavioral: Phone Calls
18 Not yet recruiting Allo HSCT Using RIC for Hematological Diseases
Conditions: Acute Myelogenous Leukemia;   Acute Lymphocytic Leukemia;   Chronic Myelogenous Leukemia;   Plasma Cell Leukemia;   Myelodysplastic Syndromes;   Chronic Lymphocytic Leukemia;   Small Lymphocytic Lymphoma;   B-Cell Lymphoma;   Follicular Lymphoma;   Lymphoplasmacytic Lymphoma;   Mantle-Cell Lymphoma;   Prolymphocytic Leukemia;   Lymphoblastic Lymphoma;   Burkitt's Lymphoma;   Non-Hodgkin's Lymphoma;   Multiple Myeloma;   Myeloproliferative Syndromes;   Hematological Diseases
Interventions: Drug: Allopurinol;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: ATG;   Radiation: TBI;   Drug: Tacrolimus;   Drug: MMF;   Biological: Peripheral Blood Stem Cells;   Biological: Related or Unrelated Bone Marrow Cells
19 Recruiting Modified MRCUKALLⅫ/ECOGE2993 Regimen for ALL
Condition: Leukaemia,Lymphoblastic
Interventions: Drug: Vincristine;   Drug: Daunorubicin;   Drug: Pegaspargase;   Drug: Prednisone;   Drug: Intrathecal Methotrexate;   Drug: Cyclophosphamide;   Drug: Cytarabine;   Drug: 6-Mercaptopurine;   Drug: Methotrexate;   Drug: Etoposide;   Drug: dexamethasone;   Drug: thioguanine;   Drug: intrathecal cytarabine
20 Recruiting URMC Related Haplo-identical Donor BMT
Conditions: Hematological Disease;   Immune Deficiencies;   Solid Tumors;   Myelofibrosis;   Multiple Myeloma;   Lymphoma
Interventions: Radiation: Total Body Irradiation 1200 cGy;   Drug: Fludarabine;   Drug: Pre-Stem Cell Infusion Cyclophosphamide;   Drug: Pre-Stem Cell Infusion Mesna;   Drug: Busulfan;   Drug: Melphalan;   Procedure: Stem Cell Infusion;   Drug: Post-Stem Cell Infusion Cyclophosphamide;   Drug: Post-Stem Cell Infusion Mesna

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Indicates status has not been verified in more than two years