Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
42 studies found for:    Open Studies | "intraocular melanoma"
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Rank Status Study
21 Recruiting Influence of Oral Treatment With Citicoline for the Prevention of Radiation Optic Neuropathy in Patients Treated for Uveal Melanomas With Proton Beam Therapy
Condition: Uveal Melanoma
Interventions: Dietary Supplement: CITICOLINE;   Dietary Supplement: PLACEBO
22 Recruiting Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer
Conditions: Brain and Central Nervous System Tumors;   Intraocular Melanoma;   Lung Cancer;   Melanoma (Skin);   Metastatic Cancer;   Neuroblastoma;   Ovarian Cancer;   Retinoblastoma;   Sarcoma;   Small Intestine Cancer
Interventions: Genetic: DNA analysis;   Other: immunologic technique;   Other: pharmacological study;   Radiation: iodine I 131 monoclonal antibody 3F8;   Radiation: 131I-3F8
23 Unknown  A Phase II Study of Sunitinib Versus Dacarbazine in the Treatment of Patients With Metastatic Uveal Melanoma
Condition: Metastatic Uveal Melanoma
Interventions: Drug: Dacarbazine;   Drug: Sunitinib
24 Recruiting SIR-Spheres® 90Y Microspheres Treatment of Uveal Melanoma Metastasized to Liver
Condition: Stage IV Uveal Melanoma
Intervention: Device: Sir-Spheres®
25 Unknown  Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom
Conditions: Bladder Cancer;   Brain and Central Nervous System Tumors;   Esophageal Cancer;   Intraocular Melanoma;   Kidney Cancer;   Lymphoma;   Melanoma (Skin);   Pancreatic Cancer;   Transitional Cell Cancer of the Renal Pelvis and Ureter
Interventions: Genetic: DNA analysis;   Genetic: polymorphism analysis;   Other: laboratory biomarker analysis;   Other: questionnaire administration
26 Unknown  Treatment Of Radiation Retinopathy Trial
Condition: Uveal Melanoma
Interventions: Drug: ranibizumab;   Drug: triamcinolone acetonide;   Other: sham
27 Recruiting CDX-1401 and Poly-ICLC Vaccine Therapy With or Without CDX-301in Treating Patients With Stage IIB-IV Melanoma
Conditions: Carcinoma of Unknown Primary Origin;   Iris Melanoma;   Medium/Large Size Posterior Uveal Melanoma;   Mucosal Melanoma;   Ocular Melanoma With Extraocular Extension;   Small Size Posterior Uveal Melanoma;   Stage IIB Skin Melanoma;   Stage IIB Uveal Melanoma;   Stage IIC Skin Melanoma;   Stage IIIA Skin Melanoma;   Stage IIIA Uveal Melanoma;   Stage IIIB Skin Melanoma;   Stage IIIB Uveal Melanoma;   Stage IIIC Skin Melanoma;   Stage IIIC Uveal Melanoma;   Stage IV Skin Melanoma;   Stage IV Uveal Melanoma
Interventions: Biological: recombinant flt3 ligand;   Biological: DEC-205/NY-ESO-1 Fusion Protein CDX-1401;   Biological: Neoantigen-based Melanoma-Poly-ICLC Vaccine;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study
28 Recruiting Trial of AEB071 in Combination With BYL719 in Patients With Melanoma
Condition: Uveal Melanoma
Interventions: Drug: AEB071;   Drug: BYL719
29 Recruiting INCB024360 and Vaccine Therapy in Treating Patients With Stage III-IV Melanoma
Conditions: Mucosal Melanoma;   Recurrent Melanoma;   Recurrent Uveal Melanoma;   Stage IIIA Skin Melanoma;   Stage IIIA Uveal Melanoma;   Stage IIIB Skin Melanoma;   Stage IIIB Uveal Melanoma;   Stage IIIC Skin Melanoma;   Stage IIIC Uveal Melanoma;   Stage IV Skin Melanoma;   Stage IV Uveal Melanoma
Interventions: Drug: IDO1 Inhibitor INCB024360;   Biological: MELITAC 12.1 Peptide Vaccine;   Other: Laboratory Biomarker Analysis
30 Recruiting Study Of Surgical Radiation Shielding With Vitrectomy And Silicone Oil Tamponade For The Protection Of Radiation Induced Ocular Injury
Condition: Choroidal Melanoma
Intervention: Other: 1000CsK Silicon Oil Tamponade
31 Recruiting Vorinostat in Treating Patients With Metastatic Melanoma of the Eye
Conditions: Ocular Melanoma With Extraocular Extension;   Recurrent Uveal Melanoma
Interventions: Drug: Vorinostat;   Other: Laboratory Biomarker Analysis
32 Unknown  Combined PET/CT Imaging for the Early Detection of Ocular Melanoma Metastasis Compared to CT Scanning Alone
Conditions: Ocular Melanoma;   Choroidal Melanoma;   Uveal Melanoma
Intervention:
33 Recruiting Clinical and Histopathologic Characteristics of BAP1 Mutations
Conditions: Malignant Pleural Mesothelioma (MPM);   Choroidal Nevus;   Primary Uveal Melanoma (UM);   Metastatic Uveal Melanoma (UM);   Renal Cell Carcinoma;   Cholangiocarcinoma
Intervention: Other: tumor specimens
34 Unknown  Cytogenetic Study of Ocular Melanoma
Condition: Choroidal Melanoma
Intervention:
35 Recruiting Ipilimumab for Uveal Melanoma
Condition: Melanoma
Intervention: Drug: Ipilimumab
36 Recruiting Vascular Response to Brachytherapy Using Functional OCT
Condition: Uveal Melanoma
Intervention:
37 Recruiting Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Ocular Melanoma
Conditions: Metastatic Ocular Melanoma;   Metastatic Uveal Melanoma
Interventions: Drug: Aldesleukin;   Drug: Cyclophosphamide;   Drug: Fludarabine;   Biological: Young TIL
38 Recruiting Ph 1 Trial of ADI-PEG 20 Plus Cisplatin in Patients With Metastatic Melanoma
Condition: Cutaneous Melanoma, Uveal Melanoma, Ovarian Carcinoma or Other Advanced Solid Tumors
Intervention: Drug: ADI-PEG 20
39 Unknown  Optical Coherence Tomography of Retinal Abnormalities Associated With Choroidal Nevus, Choroidal Melanoma and Choroidal Melanoma Treated With Iodine-125 Brachytherapy
Condition: Ocular Melanoma
Intervention:
40 Unknown  Melanoma Inhibitory Activity (MIA): A Serological Marker for Metastatic Uveal Melanoma
Conditions: Melanoma;   Radiotherapy;   Metastatic Disease
Intervention: Procedure: Treatment of metastatic disease

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