Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
43 studies found for:    Open Studies | "beta-Thalassemia"
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Rank Status Study
21 Not yet recruiting Efficacy and Safety of Efficacy and Safety of Continued Iron Chelation Therapy In Poly-transfused Thalassemia Patients With Low Serum Ferritin (< 500 ng/ml)
Conditions: Beta-thalassemia;   Serum Ferritin;   Iron Chelation Therapy
Intervention: Drug: desferal, ferriprox, blood transfusion
22 Unknown  GDF 15 in Sickle Cell Disease and Hereditary Spherocytosis
Conditions: Patients With Thalassemia Intermedia,;   Congenital Dyserythropoietic Anemia Type I
Intervention:
23 Recruiting A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
Conditions: Hematologic Malignancies;   Certain:;   Inherited Disorders of Metabolism;   Inherited Abnormalities of Erythrocyte Differentiation or Function;   Inherited Abnormalities of Platelets;   Disorders of the Immune System;   Histiocytic Disorders;   X-linked Adrenoleukodystrophy;   Primary Immunodeficiency Diseases;   Bone Marrow Failure;   Beta-thalassemia
Intervention: Drug: A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)
24 Unknown  Stem Cell Transplant in Sickle Cell Disease and Thalassemia
Conditions: Sickle Cell Disease;   Beta Thalassemia
Interventions: Drug: Busulfan;   Drug: Fludarabine;   Drug: Alemtuzumab;   Procedure: Allogeneic stem cell transplant
25 Recruiting CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant
Conditions: Leukemia;   Lymphoma;   Bone Marrow Failure;   Immunodeficiencies;   Histiocytosis;   Sickle Cell Disease;   Beta Thalassemia;   Inborn Errors of Metabolism
Interventions: Drug: Full Intensity with TBI;   Drug: Full Intensity;   Drug: Reduced Intensity;   Drug: Reduced Intensity (Fanconi)
26 Recruiting Decision Aid for Therapeutic Options In Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Anemia;   Hemoglobin SS;   Hemoglobin SC;   Hemoglobin Beta Thalassemia
Interventions: Other: Decision Aid;   Other: Standard Practice
27 Recruiting Detection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic Counter
Conditions: Thalassemia;   Iron Deficiency
Intervention: Procedure: Observation of results from laboratory tests
28 Not yet recruiting A Case Control Study to Evaluate the Cognitive and Brain Function of β-thalassemia Patients.
Conditions: Thalassemia;   Brain Function (Measured by ERP Level)
Intervention:
29 Recruiting Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure
Conditions: Sickle Cell Disease;   Thalassemia;   Stem Cell Transplantation;   Graft vs Host Disease
Interventions: Drug: Alemtuzumab;   Drug: Sirolimus;   Drug: Cyclophosphamide;   Drug: Pentostatin;   Drug: Radiotherapy
30 Unknown  The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response Study
Condition: Thalassemia Major
Interventions: Drug: Vitamin D3;   Drug: Placebo
31 Recruiting High-Tc Susceptometer to Monitor Transfusional Iron Overload
Conditions: Transfusional Iron Overload;   Thalassemia Major;   Sickle Cell Disease;   Myelodysplastic Syndromes;   Aplastic Anemia
Intervention: Device: Hepatic biomagnetic susceptibility measurement
32 Recruiting Study of Efficacy and Safety of INC424 in Regularly Transfused Patients With Thalassemia.
Condition: Thalassemia Major
Intervention: Drug: INC424 (ruxolitinib)
33 Recruiting Endocrine and Nutritional Assessment in B Thalassemia Major
Condition: Thalassemia
Intervention: Other: Nutritional recommendations
34 Recruiting Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia
Condition: Thalassemia Major With Severe Transfusional Iron Overload
Intervention: Drug: Deferasirox and deferiprone
35 Recruiting Demographic, Clinical, Laboratory and Genetical Characteristics of Patients With Beta Thalassemia Intermedia
Condition: Thalassemia
Intervention: Genetic: Laboratory analysis.
36 Unknown  Interferon and Ribavirin Treatment in Patients With Hemoglobinopathies
Condition: Hemoglobinopathies
Intervention: Drug: PEG-IFN alpha2a or PEG-IFN alpha2b and Ribavirin
37 Recruiting Utility of Fibroscan in Estimating Hepatic Iron Concentration
Condition: Hereditary Anemias
Intervention: Procedure: Fibroscan
38 Not yet recruiting Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients
Condition: Chronic Iron Overload
Interventions: Drug: Deferiprone;   Drug: Deferasirox
39 Recruiting Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Drug: panobinostat
40 Recruiting CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant
Conditions: Chronic Myeloid Leukemia (CML);   Acute Myelogenous Leukemia (AML);;   Myelodysplastic Syndrome (MDS);;   Juvenile Myelomonocytic Leukemia (JMML);;   Acute Lymphoblastic Leukemia (ALL);;   Lymphoma (Hodgkin's and Non-Hodgkin's)
Interventions: Device: CliniMACS CD34+ Reagent System;   Drug: Thiotepa;   Drug: Cyclophosphamide;   Drug: Alemtuzumab;   Drug: Tacrolimus;   Drug: Melphalan;   Drug: Busulfan;   Drug: Fludarabine

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Indicates status has not been verified in more than two years