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22 studies found for:    Open Studies | "alpha 1-Antitrypsin Deficiency"
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Rank Status Study
1 Recruiting Alpha-1 Antitrypsin Deficiency Adult Liver Study
Condition: Alpha-1 Antitrypsin Deficiency
Intervention: Procedure: Liver Biopsy
2 Not yet recruiting Microbioma in Sputa From COPD With Alpha-1 Antitrypsin Deficiency
Condition: Alpha-1 Antitrypsin Deficiency
Intervention: Other: collection of sputum
3 Recruiting A Study of ARC-AAT in Healthy Volunteer Subjects and Patients With Alpha-1 Antitrypsin Deficiency (AATD)
Condition: Alpha-1 Antitrypsin Deficiency
Interventions: Drug: ARC-AAT Injection;   Other: Placebo
4 Recruiting Epigenetic Regulation of Immunity in Alpha-1 Anti-trypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention:
5 Recruiting Safety and Pharmacokinetics of Alpha-1 MP in Patients With Alpha1-Antitrypsin Deficiency
Condition: Alpha1-Antitrypsin Deficiency
Intervention: Biological: Alpha-1 MP
6 Not yet recruiting Long-term Safety of Alpha1-Proteinase Inhibitor (Human) in Japanese Subjects With Alpha1 Antitrypsin Deficiency
Condition: Alpha1-Antitrypsin Deficiency
Intervention: Biological: Alpha-1 MP
7 Recruiting Liver Disease in Patients With alpha1-antitrypsin Deficiency
Condition: alpha1-antitrypsin Deficiency
Intervention: Other: No intervention
8 Recruiting Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency
Conditions: Alpha-1-antitrypsin Deficiency;   Liver Cirrhosis
Interventions: Drug: Drug-Carbamazepine (Tegretol XR);   Drug: Carbamazepine (Tegretol XR) Placebo
9 Not yet recruiting Safety, Tolerability and Effect of ARC-AAT Injection on Circulating and Intrahepatic Alpha-1 Antitrypsin Levels
Condition: Alpha-1 Antitrypsin Deficiency
Intervention: Drug: ARC-AAT Injection
10 Recruiting Ph 3/4 GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study
Condition: Alpha1-antitrypsin Deficiency
Intervention: Biological: GLASSIA
11 Recruiting Alpha-1 Foundation Research Registry
Condition: Alpha 1-Antitrypsin Deficiency
Intervention:
12 Recruiting Alpha-1 Coded Testing(ACT) Study
Condition: Alpha-1 Antitrypsin Deficiency
Intervention: Procedure: Alpha-1 Antitrypsin Genotype
13 Not yet recruiting Safety Study of Gene Transfer Vector to Treat Alpha1-antitrypsin (A1AT) Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Genetic: ADVM-043
14 Recruiting AL1TER™: Alpha-1 Therapy, Evaluation, and Research Patient Registry
Condition: Alpha-1 Anti-trypsin Deficiency
Intervention:
15 Recruiting Environment Effect on Six-Minute Walk Test Performance
Conditions: Chronic Obstructive Pulmonary Disease;   Alpha-1 Antitrypsin Deficiency
Interventions: Other: six-minute walk study indoors;   Other: six-minute walk study outdoors
16 Recruiting Polygen Defi-Alpha: Genetic Polymorphisms Study in Children With Alpha-1 Antitrypsin Deficiency, Included in the DEFI-ALPHA Cohort
Condition: Children With a Deficiency of Alpha-1 Antitrypsin
Intervention: Other: blood sampling
17 Recruiting Stage 1 Study of ARALAST NP and GLASSIA in A1PI
Conditions: Chronic Obstructive Pulmonary Disease;   Alpha1-antitrypsin Deficiency
Interventions: Biological: ARALAST NP 60 mg/kg;   Biological: ARALAST NP 120 mg/kg;   Biological: GLASSIA 60 mg/kg;   Biological: GLASSIA 120 mg/kg;   Biological: Human Albumin 2%
18 Recruiting Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD)
Condition: Pulmonary Emphysema in Alpha-1 PI Deficiency
Interventions: Biological: Alpha1-proteinase inhibitor (human), modified process (Alpha-1 MP);   Other: 0.9% Sodium Chloride for Injection, USP
19 Recruiting Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs
Conditions: Alpha-1 Antitrypsin Deficiency;   AAT Deficiency;   AATD;   Cystic Fibrosis (CF)
Interventions: Procedure: History and physical exam.;   Procedure: Blood draw.;   Procedure: Pulmonary function testing.;   Drug: Albuterol inhaler.
20 Recruiting Evaluating the Genetic Causes and Progression of Cholestatic Liver Diseases (LOGIC)
Conditions: Liver Diseases;   Alagille Syndrome;   Alpha 1-Antitrypsin Deficiency
Intervention:

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Study has passed its completion date and status has not been verified in more than two years.