| 1 |
NCT03561285 |
Recruiting
New |
Antiphospholipid Antibodies & Osteopontin as Risk Factors for Cerebrovascular Stroke in Young Adults |
|
- Diagnostic Test: antiphospholipid Abs
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
|
500 |
All |
18 Years to 49 Years (Adult) |
NCT03561285 |
17200187 |
|
July 1, 2018 |
May 1, 2019 |
May 1, 2020 |
June 19, 2018 |
June 19, 2018 |
|
- Assiut University Hospital
Assiut, Egypt
|
|
| 2 |
NCT03512028 |
Recruiting |
Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults |
|
- Behavioral: RLIC
- Behavioral: Sham conditioning
- Behavioral: Muscle strength training
- (and 2 more...)
|
Interventional
|
Phase 1 |
- Washington University School of Medicine
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- One-repetition maximum of wrist extensors
- Driving simulator score
- Balance score
|
40 |
All |
18 Years to 40 Years (Adult) |
NCT03512028 |
NIHR01HD085930-Aim1
R01HD085930 |
|
November 8, 2017 |
December 31, 2018 |
July 31, 2019 |
April 30, 2018 |
June 19, 2018 |
|
- Washington University School of Medicine
Saint Louis, Missouri, United States
|
|
| 3 |
NCT03000166 |
Recruiting |
Step-Up Intervention for Self-Management of Fatigue in Young Adults Receiving Chemotherapy |
- Young Adult, Cancer, Physical Activity
|
- Behavioral: Step-Up Intervention
|
Interventional
|
Not Applicable |
- University of Wisconsin, Milwaukee
- Froedtert Hospital
- Children's Hospital and Health System Foundation, Wisconsin
- Medical College of Wisconsin
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Self-efficacy for physical activity
- Self-regulation of physical activity
- Physical activity
- Fatigue severity
|
75 |
All |
18 Years to 39 Years (Adult) |
NCT03000166 |
P20NR015339-PP3
P20NR015339 |
|
January 31, 2017 |
August 2018 |
August 2018 |
December 21, 2016 |
May 3, 2018 |
|
- Froedtert Hospital
Milwaukee, Wisconsin, United States - Children's Hospital of Wisconsin
Milwaukee, Wisconsin, United States
|
|
| 4 |
NCT03559413 |
Recruiting
New |
Patient-individualized Peptide Vaccination Based on Tumor-specific Mutations in Children and Young Adults With Primary/Relapsed ALL |
- Primary/Relapsed Acute Lymphoblastic Leukemia (ALL) of Childhood, Adolescents and Young Adults
|
- Biological: Individual peptide vaccination with adjuvant GM-CSF and Imiquimod
|
Interventional
|
Phase 1
Phase 2 |
- University Children’s Hospital Tuebingen
- German Cancer Research Center
- German Cancer Consortium (DKTK)
- (and 2 more...)
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Primary endpoint is "success of treatment" defined as a patient showing a vaccination-induced T-cell response without unacceptable toxicity and acute GvHD of Grade III or higher or extensive chronic GvHD until day 120 (after 10 vaccinations).
- To evaluate CD4+ and/or CD8+ T-cell responses over the vaccination period.
- To evaluate changes in minimal residual disease (MRD) during and after treatment.
- (and 2 more...)
|
30 |
All |
1 Year to 30 Years (Child, Adult) |
NCT03559413 |
IVAC-ALL-1
2015-005281-29 |
|
June 2016 |
December 2019 |
June 2020 |
June 18, 2018 |
June 18, 2018 |
|
- University Medical Center for Children and Adolescents Heidelberg
Heidelberg, Baden-Württemberg, Germany - University Children's Hospital Tübingen
Tübingen, Baden-Württemberg, Germany - University Children's Hospital Munich, Center for Pediatric Hematology and Oncology
München, Bayern, Germany - (and 2 more...)
|
|
| 5 |
NCT03002727 |
Recruiting |
Role of CD133 & Microsatellite Status in Evaluation of Rectosigmoid Cancer Young Adults Received Neoadjuvant Treatment |
- Colorectal Cancer Genetics
- Young Adult
|
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Differential expression of CD133 based on microsatellite status and correlation with clinicopathological features.
- Assess the microsatellite status of young adult with rectosigmoid cancer
- The effect of radiotherapy on the count of CD 133 +ve cells
- (and 2 more...)
|
30 |
All |
18 Years to 40 Years (Adult) |
NCT03002727 |
2016/06/17-002 |
|
December 2016 |
December 2018 |
January 2019 |
December 26, 2016 |
May 8, 2018 |
|
- Ereny Samwel Poles
Assiut, Egypt
|
|
| 6 |
NCT03016728 |
Recruiting |
Physical Activity for Adolescent and Young Adult Cancer Survivors |
- Adolescent and Young Adult Cancer Survivors
|
- Behavioral: Physical Activity
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Recruitment Rates
- Retention Rates
- Adherence Rates
- (and 17 more...)
|
30 |
All |
15 Years to 44 Years (Child, Adult) |
NCT03016728 |
Ottawa |
|
September 11, 2017 |
March 2018 |
June 2018 |
January 11, 2017 |
October 9, 2017 |
|
- University of Ottawa
Ottawa, Ontario, Canada
|
|
| 7 |
NCT02916472 |
Recruiting |
CyberCycling to Reduce Therapeutic Side Effects and Improve Quality of Life in AYA Cancers |
- Adolescent and Young Adult Cancers
|
- Behavioral: CyberCycling
- Behavioral: Stretching
- Behavioral: Resistance Bands
|
Interventional
|
Not Applicable |
- Case Comprehensive Cancer Center
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Proportion of Patient Adherence as recorded by attendance log
- Median change of peak pulmonary oxygen uptake (VO2Peak)
- Median Tolerance of Exercise Intensity as measured by the Preference for and Tolerance of Exercise Intensity Questionnaire (PRETIE-Q) score
- (and 7 more...)
|
20 |
All |
15 Years to 30 Years (Child, Adult) |
NCT02916472 |
CASE4Z16 |
|
August 24, 2016 |
February 2019 |
August 2019 |
September 27, 2016 |
January 31, 2018 |
|
- University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center
Cleveland, Ohio, United States
|
|
| 8 |
NCT03094520 |
Recruiting |
Cognitive Embodiment Activation by tDCS |
|
- Device: tDCS
- Device: sham-tDCS
|
Interventional
|
Not Applicable |
- Charite University, Berlin, Germany
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- response time in semantic decision task
- performance in attentional load task
- performance in motor task
- (and 3 more...)
|
24 |
All |
18 Years to 30 Years (Adult) |
NCT03094520 |
GEST |
GEST |
May 2016 |
July 2018 |
October 2018 |
March 29, 2017 |
March 30, 2017 |
|
|
|
| 9 |
NCT02989038 |
Recruiting |
Reactions to Reduced Nicotine Cigarettes in Young Adult Low-Frequency Smokers |
|
- Other: Very Low Nicotine Content Cigarettes
- Other: Intermediate Nicotine Content Cigarettes
- Other: Normal Nicotine Content Cigarettes
|
Interventional
|
Not Applicable |
- Duke University
- National Institute on Drug Abuse (NIDA)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Basic Science
|
- Subjective reactions to fixed doses of tobacco smoke
- Cigarette choice
- Mood and Affect
- (and 3 more...)
|
90 |
All |
18 Years to 25 Years (Adult) |
NCT02989038 |
Pro00075882
R01DA042532 |
NicRed |
January 2017 |
April 2019 |
April 2019 |
December 12, 2016 |
June 19, 2018 |
|
- Duke University Medical Center
Durham, North Carolina, United States
|
|
| 10 |
NCT02596503 |
Recruiting |
A Study of Eribulin in Combination With Oral Irinotecan for Adolescent and Young Adult Patients With Relapsed or Refractory Solid Tumors |
- Relapsed Solid Tumors
- Refractory Solid Tumors
|
- Drug: Eribulin
- Drug: Irinotecan
- Other: Cefixime
|
Interventional
|
Phase 1 |
- University of Colorado, Denver
- University of Kentucky
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The recommended Phase II dose of eribulin when used in combination with oral irinotecan
- The number of patients with adverse events (according to CTCAE V.4) in patients receiving the combination of eribulin and irinotecan
- The best overall response based on RECIST 1.1 criteria
- (and 3 more...)
|
21 |
All |
13 Years to 30 Years (Child, Adult) |
NCT02596503 |
15-0659 |
|
October 2015 |
October 2018 |
September 2020 |
November 4, 2015 |
January 17, 2018 |
|
- Children's Hospital Colorado
Aurora, Colorado, United States - University of Kentucky
Lexington, Kentucky, United States - University of Texas, Southwestern Medical Center
Dallas, Texas, United States
|
|
| 11 |
NCT02736981 |
Recruiting |
Low Intensity Weight Loss for Young Adults |
|
- Behavioral: Behavioral Weight Loss (BWL)
- Behavioral: BWL + Autonomous Motivation
- Behavioral: BWL + Extrinsic Motivation
|
Interventional
|
Not Applicable |
- Virginia Commonwealth University
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Weight Loss
- Percent Weight Loss
- Change in Body Mass Index
- (and 5 more...)
|
381 |
All |
18 Years to 25 Years (Adult) |
NCT02736981 |
HM20002772
R01DK103668 |
REACH |
January 2016 |
February 2019 |
September 2019 |
April 13, 2016 |
May 2, 2018 |
|
- Virginia Commonwealth University, School of Medicine
Richmond, Virginia, United States
|
|
| 12 |
NCT01667952 |
Recruiting |
Prospective Ascertainment for Late Effects Among Survivors of Cancer, Tumor, or a Related Illness |
- Pediatric or Young Adult Cancer Survivors
|
- Genetic: Family History Questionnaire (FHQ)
- Genetic: Salvia sample
- Other: Blood sample
|
Observational
|
|
- Memorial Sloan Kettering Cancer Center
|
Other |
- Observational Model: Family-Based
- Time Perspective: Prospective
|
- establish a registry of DNA
|
2000 |
All |
Child, Adult, Older Adult |
NCT01667952 |
12-143 |
|
August 2012 |
August 2022 |
August 2022 |
August 17, 2012 |
December 21, 2017 |
|
- Memorial Sloan Kettering Cancer Center
New York, New York, United States
|
|
| 13 |
NCT03363711 |
Recruiting |
AYA STEPS RCT: AYA Self-Management Via Texting, Education & Plans for Survivors |
- Adolescent and Young Adult (AYA) Cancer Survivors
|
|
Observational
|
|
- Abramson Cancer Center of the University of Pennsylvania
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Number of Completed mobile data and questionnaires
|
25 |
All |
15 Years to 29 Years (Child, Adult) |
NCT03363711 |
UPCC 26916 |
|
March 1, 2017 |
March 1, 2019 |
March 1, 2019 |
December 6, 2017 |
December 6, 2017 |
|
- Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
|
|
| 14 |
NCT03446170 |
Recruiting |
Effect of Cigarette Pack Warnings and Packaging Among Young Adult Smokers |
|
- Behavioral: Graphic cigarette warning labels, plain packaging
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Cigarette purchase appeal
- Motivation to quit smoking
- Cigarette smoking behavior
- (and 2 more...)
|
400 |
All |
18 Years to 30 Years (Adult) |
NCT03446170 |
2014-1031 |
|
September 1, 2014 |
August 31, 2020 |
August 31, 2020 |
February 26, 2018 |
February 26, 2018 |
|
- Georgetown University
Washington, District of Columbia, United States
|
|
| 15 |
NCT02723552 |
Not yet recruiting |
Trial of Exercise to Prevent HypeRtension in Young Adults |
- Hypertension
- Premature Birth
|
- Behavioral: Aerobic Exercise
|
Interventional
|
Not Applicable |
- University of Oxford
- Wellcome Trust
- Oxford Brookes University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- 16 Week Blood Pressure
- 52 Week Blood Pressure
- Peak VO2
- (and 13 more...)
|
200 |
All |
18 Years to 35 Years (Adult) |
NCT02723552 |
TEPHRA Version 1 16/SC/0016 |
TEPHRA |
March 2016 |
May 2018 |
December 2019 |
March 30, 2016 |
March 30, 2016 |
|
- Cardiovascular Clinical Research Facility, Dept of Cardiovascular Medicine, University of Oxford
Oxford, Oxfordshire, United Kingdom
|
|
| 16 |
NCT03158051 |
Recruiting |
Young Adult Hypertension Self-Management Clinical Trial |
- Hypertension
- Blood Pressure
- Lifestyle Risk Reduction
|
- Behavioral: Home Blood Pressure Monitoring
- Behavioral: Telephone Health Coaching
|
Interventional
|
Not Applicable |
- University of Wisconsin, Madison
- National Heart, Lung, and Blood Institute (NHLBI)
- Aurora Health Care
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- 24-hour Systolic Ambulatory Blood Pressure (mmHg)
- 24-hour Diastolic Ambulatory Blood Pressure (mmHg)
- Change in Standing Weight (kg)
- (and 8 more...)
|
310 |
All |
18 Years to 39 Years (Adult) |
NCT03158051 |
2017-0372 |
MyHEART |
October 2, 2017 |
December 31, 2021 |
April 30, 2022 |
May 17, 2017 |
November 22, 2017 |
|
- University of Wisconsin School of Medicine & Public Health
Madison, Wisconsin, United States - Aurora Health Care
Milwaukee, Wisconsin, United States
|
|
| 17 |
NCT01884922 |
Recruiting |
Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young Adults |
- Refractory Low-grade Gliomas
- Recurrent Low-grade Gliomas
|
- Drug: Nilotinib
- Drug: Vinblastine
|
Interventional
|
Phase 1 |
- Gustave Roussy, Cancer Campus, Grand Paris
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Safety Assessment - Dose-Limiting Toxicity (DLT)
|
50 |
All |
6 Months to 20 Years (Child, Adult) |
NCT01884922 |
2012-003005-10 Phase I
2012/1883
022 |
VINILO |
May 2013 |
May 2017 |
May 2019 |
June 24, 2013 |
January 26, 2017 |
|
- Medical University of Vienna
Vienna, Austria - Rigshospitalet
Copenhagen, Denmark - Gustave Roussy
Villejuif, Val de Marne, France - (and 6 more...)
|
|
| 18 |
NCT01887522 |
Recruiting |
Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults |
- Refractory Low-grade Gliomas
- Recurrent Low-grade Gliomas
|
- Drug: Vinblastine + Nilotinib
- Drug: Vinblastine
|
Interventional
|
Phase 2 |
- Gustave Roussy, Cancer Campus, Grand Paris
- Innovative Therapies For Children with Cancer Consortium
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Progression Free Survival (PFS)
|
120 |
All |
6 Months to 20 Years (Child, Adult) |
NCT01887522 |
2012-003005-10 Phase II
2012/1883
022 |
VINILO |
June 2016 |
December 2018 |
December 2020 |
June 27, 2013 |
January 26, 2017 |
|
- Medical University of Vienna
Vienna, Austria - Rigshospitalet
Copenhagen, Denmark - Gustave Roussy
Villejuif, Val de Marne, France - (and 6 more...)
|
|
| 19 |
NCT03535714 |
Recruiting
New |
Maudsley Model of Anorexia Nervosa Treatment for Adolescents and Young Adults (MANTR-a) |
|
- Behavioral: MANTR-a treatment
|
Interventional
|
Not Applicable |
- Medical University of Vienna
- Pharmig - Gemeinsame Gesundheitsziele aus dem Rahmen-Pharmavertrag
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Increase of BMI
- Improvement of eating disorder symptomatology based on professional's rating
- Improvement of eating disorder symptomatology based on patient's self-rating
- (and 15 more...)
|
100 |
Female |
14 Years to 21 Years (Child, Adult) |
NCT03535714 |
FA765A0306 |
|
April 25, 2018 |
January 31, 2021 |
January 31, 2021 |
May 24, 2018 |
June 15, 2018 |
|
- Medical University of Vienna, Dep. of Child and Adolescent Psychiatry
Vienna, Austria
|
|
| 20 |
NCT02813135 |
Recruiting |
European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors |
- Children, Adolescents and Young Adults With Refractory or Recurrent Malignancies
|
- Drug: Ribociclib
- Drug: Topotecan
- Drug: Temozolomide
- (and 11 more...)
|
Interventional
|
Phase 1
Phase 2 |
- Gustave Roussy, Cancer Campus, Grand Paris
- National Cancer Institute, France
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Objective tumor response
- Time to progression
|
397 |
All |
up to 18 Years (Child, Adult) |
NCT02813135 |
2016-000133-40
2016/2396 |
ESMART |
August 3, 2016 |
January 2022 |
January 2022 |
June 24, 2016 |
June 14, 2018 |
|
- Gustave Roussy
Villejuif, Val De Marne, France - University Children's Hospitalermany
Heidelberg, Germany - Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Italy - (and 3 more...)
|
|
| 21 |
NCT02841735 |
Recruiting |
Young Adult Naturalistic Alcohol Study (YANAS) Using Smartphone Technology in a Simulated Laboratory Environment |
- Alcohol Use
- Alcohol Drinking
- Drinking Behavior
|
- Device: Smartphone breathalyzer device/app use
- Device: BAC estimator app use
- Device: Text messaging procedure
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Quantity of alcohol consumption
|
129 |
All |
21 Years to 25 Years (Adult) |
NCT02841735 |
IRB201500990
ID00004419 |
|
July 2016 |
December 2018 |
December 2018 |
July 22, 2016 |
December 22, 2017 |
|
- Department of Health Education and Behavior
Gainesville, Florida, United States
|
|
| 22 |
NCT01421095 |
Recruiting |
Ovarian Reserve Testing in Female Young Adult Cancer Survivors |
|
|
Interventional
|
Not Applicable |
- University of California, San Diego
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Return of menses
- Blood levels of FSH
- Blood levels of estradiol
- (and 2 more...)
|
34 |
Female |
18 Years to 35 Years (Adult) |
NCT01421095 |
ORT study |
|
January 2011 |
December 2020 |
December 2020 |
August 22, 2011 |
May 3, 2017 |
|
- UCSD Moores Cancer Center
San Diego, California, United States
|
|
| 23 |
NCT03462888 |
Recruiting |
Clinico-biological Study/Characterization of Rhabdomyosarcoma in Adolescents and Young Adults, 15-25-year-old Patients |
|
|
Observational
|
|
- Centre Oscar Lambret
- Centre Leon Berard
- Société Française de lutte contre les Cancers et les leucémies de l’Enfant et l’adolescent
- (and 2 more...)
|
Other |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Progression-free survival
- Clinical parameters of RMS in AYA
- Biological parameters of RMS in AYA
- (and 2 more...)
|
150 |
All |
15 Years to 25 Years (Child, Adult) |
NCT03462888 |
RMS-AJA-1701 |
RMS-AJA-1701 |
February 23, 2018 |
September 2018 |
September 2018 |
March 13, 2018 |
April 4, 2018 |
|
- Centre Oscar Lambret
Lille, France - CHU de Nancy
Nancy, France - Centre de Lacassagne à
Nice, France - Institut Claudius Regaud
Toulouse, France
|
|
| 24 |
NCT02222077 |
Recruiting |
Central Blood Pressure in Adolescents and Young Adults |
|
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
- Correlation coefficients (r) between 24h ambulatory central blood pressure and indices of target-organ damage
|
150 |
All |
12 Years to 25 Years (Child, Adult) |
NCT02222077 |
Central BP-TOD |
|
July 2014 |
February 2018 |
February 2018 |
August 21, 2014 |
September 14, 2017 |
|
- Hypertension Center, 3rd University Department of Medicine, Sotiria Hospital
Athens, Attica, Greece
|
|
| 25 |
NCT03476070 |
Not yet recruiting |
Adolescent and Young Adult Cancer Patients: Cognitive Toxicity on Survivorship (ACTS) |
- Breast Cancer
- Lymphoma
- Germ Cell Tumor
- Cognitive Impairment
|
|
Observational
|
|
- National University, Singapore
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Prevalence of cognitive impairment in AYA cancer patients
- Prevalence of impairment in each individual Cantab ® cognitive domain
- Prevalence of self-reported cognitive impairment
- (and 7 more...)
|
236 |
All |
15 Years to 39 Years (Child, Adult) |
NCT03476070 |
CIRB Ref. No: 2017/3139 |
|
April 1, 2018 |
April 1, 2021 |
June 1, 2021 |
March 23, 2018 |
March 27, 2018 |
|
|
|
| 26 |
NCT03176576 |
Recruiting |
Patient Navigation in the Adolescent and Young Adult (AYA) Cancer Population |
|
- Behavioral: Patient Navigator (PN)
- Other: Baseline Questionnaire
- Other: Follow-up Questionnaire
- Other: Patient Navigator Satisfaction Survey
|
Interventional
|
Not Applicable |
- H. Lee Moffitt Cancer Center and Research Institute
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Rate of Satisfaction with Patient Navigator
- Rate of Improved Questionnaire Scores
|
60 |
All |
18 Years to 39 Years (Adult) |
NCT03176576 |
MCC-18420 |
|
May 31, 2017 |
June 2019 |
June 2020 |
June 5, 2017 |
May 1, 2018 |
|
- H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, United States
|
|
| 27 |
NCT03242200 |
Recruiting |
Assessing the Acceptability of the Use of a Mobile Health App Among Young Adult Female Survivors of Childhood Cancer |
- Childhood Cancer Survivor
|
|
Interventional
|
Not Applicable |
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Villanova University
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Feasibility of mHealth app as measured by tracking all activities conducted on the app
- Adherence
- Self-Efficacy
- (and 2 more...)
|
30 |
Female |
18 Years to 30 Years (Adult) |
NCT03242200 |
J1734 |
|
September 1, 2017 |
September 2019 |
September 2019 |
August 8, 2017 |
October 9, 2017 |
|
- Johns Hopkins Hospital
Baltimore, Maryland, United States
|
|
| 28 |
NCT03332537 |
Recruiting |
Precision Pain Self-Management in Young Adults With Irritable Bowel Syndrome |
|
- Behavioral: Personalized IBS Pain SM
|
Interventional
|
Not Applicable |
- University of Connecticut
- National Institute of Nursing Research (NINR)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Supportive Care
|
- Change in pain sensitivity
- Change in gut microbiome
- Genetic variations (Pain-susceptibility SNPs genotyping)
|
80 |
All |
18 Years to 29 Years (Adult) |
NCT03332537 |
H16-152
1P20NR016605-01 |
IBS-SM |
October 1, 2016 |
August 30, 2018 |
August 30, 2018 |
November 6, 2017 |
June 13, 2018 |
|
- UConn Health Center
Farmington, Connecticut, United States - University of Connecticut
Storrs, Connecticut, United States
|
|
| 29 |
NCT02974582 |
Recruiting |
Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult Smokers |
|
- Behavioral: exposure to smoking advertising with coupon
- Behavioral: exposure to smoking advertising
- Behavioral: exposure to non health related images
- Behavioral: exposure to smoking advertising no coupon
|
Interventional
|
Not Applicable |
- National Institute on Minority Health and Health Disparities (NIMHD)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- To collect pilot data to examine the variability in beliefs, effective responses, and arousal to cigarette direct mail marketing materials between young adult smokers of high and low socioeconomic status.
- To conduct a randomized comparative trial to examine the effect of cigarette direct mail materials on beliefs, affective responses, arousal, and smoking behavior, and their variation by SES among young adult smokers.
- To select cigarette direct mail marketing materials that are perceived to be similar in their persuasiveness for Part 2 of the study.
|
530 |
All |
18 Years to 29 Years (Adult) |
NCT02974582 |
170015
17-MD-0015 |
|
November 22, 2016 |
October 6, 2019 |
October 6, 2021 |
November 28, 2016 |
March 29, 2018 |
|
- National Institutes of Health Clinical Center
Bethesda, Maryland, United States
|
|
| 30 |
NCT03149757 |
Recruiting |
Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial |
|
- Behavioral: YouTHrive
- Behavioral: Information-only Control
|
Interventional
|
Phase 2 |
- University of Minnesota - Clinical and Translational Science Institute
- University of North Carolina
- University of Michigan
- (and 6 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Change in Viral Load Among Youth Living with HIV
- Change in Viral Load Among Substance-using Youth Living with HIV
|
300 |
All |
15 Years to 24 Years (Child, Adult) |
NCT03149757 |
1U19HD089881 (SubProject 8781)
1U19HD089881 |
|
May 16, 2017 |
April 2020 |
April 2020 |
May 11, 2017 |
April 6, 2018 |
|
- University of South Florida
Tampa, Florida, United States - Emory University
Atlanta, Georgia, United States - Cook County Hospital and Health Systems CORE Center
Chicago, Illinois, United States - (and 3 more...)
|
|
| 31 |
NCT02815813 |
Recruiting |
Lifestyle Intervention for Young Adults With Serious Mental Illness |
- Schizophrenia
- Schizoaffective Disorder
- Bipolar Disorder
- (and 3 more...)
|
- Behavioral: PeerFIT
- Behavioral: BEAT
|
Interventional
|
Not Applicable |
- Dartmouth-Hitchcock Medical Center
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in weight
- Change in 6-minute walk test
- Change in weight loss self-efficacy assessed using the Weight Efficacy Lifestyle (WEL) questionnaire
- (and 3 more...)
|
144 |
All |
18 Years to 35 Years (Adult) |
NCT02815813 |
STUDY00029586
R01MH110965 |
|
March 1, 2017 |
March 2020 |
June 2020 |
June 28, 2016 |
March 13, 2018 |
|
- Vinfen
Cambridge, Massachusetts, United States - The Mental Health Center of Greater New Hampshire
Manchester, New Hampshire, United States
|
|
| 32 |
NCT03148080 |
Recruiting |
Work Ability in Young Adult Survivors |
|
- Other: Data Collection Only:
|
Observational
|
|
- Wake Forest University Health Sciences
- National Cancer Institute (NCI)
|
Other / NIH |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
- Work Ability Index
- Work Limitations Questionnaire
- PROMIS Applied Cognition - Abilities
- (and 10 more...)
|
200 |
All |
25 Years to 34 Years (Adult) |
NCT03148080 |
IRB00034074
5R21CA191989-02
REBAWF10217 |
WAYS |
April 2, 2018 |
September 1, 2019 |
September 1, 2019 |
May 10, 2017 |
June 14, 2018 |
|
- Wake Forest School of Medicine
Winston-Salem, North Carolina, United States
|
|
| 33 |
NCT03024164 |
Recruiting |
Stroke Registration of Young Adults in China |
|
- Other: Treatment following current guidelines
|
Observational
|
|
- Yi Yang
- Jiujiang No.1 People's Hospital
- Dezhou People's Hospital
- (and 20 more...)
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Stroke recurrence
- Post-stroke disability
- Cardiovascular death
- (and 2 more...)
|
3000 |
All |
18 Years to 45 Years (Adult) |
NCT03024164 |
REACH |
REACH |
November 26, 2017 |
December 31, 2019 |
December 31, 2019 |
January 18, 2017 |
December 5, 2017 |
|
- First Hospital of Jilin University
Changchun, Jilin, China
|
|
| 34 |
NCT03315208 |
Recruiting |
Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders |
- Substance Use Disorders
- Depression
- Anxiety
- (and 3 more...)
|
- Behavioral: Unified Protocol (UP)
- Other: Treatment as Usual (TAU)
|
Interventional
|
Not Applicable |
- Massachusetts General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Acceptability of adding UP group intervention to TAU
- Feasibility of adding UP group intervention to TAU
- Anxiety symptoms
- (and 6 more...)
|
50 |
All |
18 Years to 26 Years (Adult) |
NCT03315208 |
2017P001274 |
ARMS UP |
November 22, 2017 |
October 31, 2018 |
October 31, 2018 |
October 20, 2017 |
November 27, 2017 |
|
- Massachusetts General Hospital Addiction Recovery Management Service
Boston, Massachusetts, United States
|
|
| 35 |
NCT02995551 |
Recruiting |
Danish Rct on Exercise Versus Arthroscopic Meniscal Surgery for Young Adults |
|
- Procedure: Arthroscopic meniscal repair or resection
- Behavioral: Exercise and education
|
Interventional
|
Not Applicable |
- University of Southern Denmark
- Aarhus University Hospital
- Copenhagen University Hospital, Hvidovre
- (and 12 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- the Knee Injury and Osteoarthritis Outcome Score (KOOS4)
- The five KOOS subscales
- Western Ontario Meniscal Evaluation Tool (WOMET)
- (and 5 more...)
|
140 |
All |
18 Years to 40 Years (Adult) |
NCT02995551 |
S-20160151
DFF - 6110-00045 |
DREAM |
January 2017 |
December 2020 |
December 2020 |
December 16, 2016 |
June 7, 2018 |
|
- Department of Orthopedic Surgery, Aalborg University Hospital
Aalborg, Denmark - Department of Sports Traumatology, Aarhus University Hospital
Aarhus, Denmark - Department of Orthopedic Surgery, Copenhagen University Hospital, Amager-Hvidovre
Copenhagen, Denmark - (and 4 more...)
|
|
| 36 |
NCT02790892 |
Recruiting |
Creative Arts Diabetes Initiative for Youth/Young Adults Transitioning to Adult Care |
- Coping Behavior
- Emotional Distress
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
|
- Behavioral: Art therapy - pre and post test measures
|
Interventional
|
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Decrease diabetes related distress
- Increase social support
- Increase emotional
|
20 |
All |
15 Years to 24 Years (Child, Adult) |
NCT02790892 |
HS19577 (H2016:119) |
CADI |
April 2016 |
December 2018 |
December 2018 |
June 6, 2016 |
May 3, 2018 |
|
- University of Manitoba
Winnipeg, Manitoba, Canada
|
|
| 37 |
NCT02028455 |
Recruiting |
A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD19 for Relapsed/Refractory CD19+ Leukemia |
|
- Biological: Patient Derived CD19 specific CAR T cells also expressing an EGFRt
|
Interventional
|
Phase 1
Phase 2 |
- Seattle Children's Hospital
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Number of Participants With Adverse Events
- Number of participants with an MRD negative complete remission after T cells infusion
- Number of Participants who have a Releasable Cell Product Generated
- (and 3 more...)
|
80 |
All |
1 Year to 26 Years (Child, Adult) |
NCT02028455 |
PLAT-02 |
|
January 2014 |
January 2020 |
January 2032 |
January 7, 2014 |
April 10, 2018 |
|
- Children's Hospital Los Angeles
Los Angeles, California, United States - Children's Hospital Oakland
Oakland, California, United States - Seattle Children's Hospital
Seattle, Washington, United States
|
|
| 38 |
NCT03313492 |
Not yet recruiting |
Modifying Young Adult Skin Cancer Risk and Protective Behaviors |
- Melanoma and Other Malignant Neoplasms of Skin
|
- Behavioral: UV4.me2
- Behavioral: UV4.me
- Behavioral: E-Pamphlet
|
Interventional
|
Not Applicable |
- Fox Chase Cancer Center
- Rutgers University - Cancer Institute of New Jersey
- University of Pennsylvania
- (and 2 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Reach: eligibility by recruitment source.
- Efficacy: Sun protection behaviors
- Efficacy: UV exposure behaviors
- (and 5 more...)
|
1540 |
All |
18 Years to 25 Years (Adult) |
NCT03313492 |
R01CA204271 |
UV4me2 |
June 2018 |
September 2020 |
December 2021 |
October 18, 2017 |
October 18, 2017 |
|
|
|
| 39 |
NCT03089541 |
Recruiting |
Electronic Cigarette Use in Young Adult Men and Women |
- Cigarette Smoking
- Tobacco Use
|
|
Interventional
|
Not Applicable |
- Yale University
- APT Foundation, Inc.
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Withdrawal scores
- Satisfaction with electronic cigarettes
- Frequency of electronic cigarette use
|
30 |
All |
18 Years to 29 Years (Adult) |
NCT03089541 |
1612018726 |
|
May 24, 2017 |
December 1, 2018 |
January 1, 2019 |
March 24, 2017 |
February 21, 2018 |
|
- Yale University
New Haven, Connecticut, United States
|
|
| 40 |
NCT02816502 |
Recruiting |
Hippocampal Plasticity of Young Adults With Childhood Adversity |
|
- Behavioral: Stress Management Skill Building Program A
- Behavioral: Stress Management Skill Building Program B
|
Interventional
|
Not Applicable |
- Mclean Hospital
- Massachusetts General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- Changes in hippocampal subfield gray matter density measured with high resolution structural MRI at 3T
- Changes in stress level measured by the Perceived Stress Scale (PSS)
- Changes in severity of depression symptom measured by Beck Depression Inventory (BDI)
- Changes in severity of anxiety symptom measured by State-Trait Anxiety Inventory (STAI)
|
60 |
All |
21 Years to 35 Years (Adult) |
NCT02816502 |
2016P000335 |
|
June 15, 2017 |
March 2021 |
December 2021 |
June 28, 2016 |
August 30, 2017 |
|
- McLean Hospital
Belmont, Massachusetts, United States
|
|
| 41 |
NCT03446105 |
Recruiting |
Promoting Quality of Life Among Young Adult Cancer Survivors |
|
- Behavioral: App-based behavioral intervention
- Behavioral: Attention control group
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Change in Adult Trait Hope Scale Score
- Change in 36-Item Short Form Health Survey (SF-36) Score
- Change in Functional Assessment of Cancer Therapy - General (FACT-G) Score
|
80 |
All |
18 Years to 39 Years (Adult) |
NCT03446105 |
IRB00086979 |
|
February 9, 2017 |
July 2018 |
July 2018 |
February 26, 2018 |
February 26, 2018 |
|
- Emory University Winship Cancer Institute
Atlanta, Georgia, United States - Markey Cancer Center
Lexington, Kentucky, United States
|
|
| 42 |
NCT02756494 |
Not yet recruiting |
Ischemic Stroke in Chinese Young Adults |
|
- Biological: Ischemic Stroke
|
Observational
|
|
- Beijing Chao Yang Hospital
|
Other |
- Observational Model: Case Control
- Time Perspective: Cross-Sectional
|
- the incidence of Ischemic Stroke in Chinese Young Adults
|
200 |
All |
18 Years to 45 Years (Adult) |
NCT02756494 |
Ischemic201603 |
|
April 2016 |
April 2018 |
December 2018 |
April 29, 2016 |
April 29, 2016 |
|
|
|
| 43 |
NCT03521401 |
Recruiting |
Effects of Exercise on Young Adult Women With ACEs: an Integrative Pilot Study |
|
|
Interventional
|
Not Applicable |
- Oklahoma State University
- National Institute of General Medical Sciences (NIGMS)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- C-reactive protein
- Brain-Derived Neurotrophic Factor
- Skeletal muscle size
- (and 11 more...)
|
45 |
Female |
18 Years to 29 Years (Adult) |
NCT03521401 |
ED17157
P20GM109097 |
|
May 1, 2018 |
March 31, 2019 |
March 31, 2019 |
May 10, 2018 |
May 10, 2018 |
|
- 192 Colvin Recreation Center
Stillwater, Oklahoma, United States
|
|
| 44 |
NCT03245723 |
Recruiting |
Cardiac Function and Metabolism in Young Adults Born Premature (PET-MRI) |
|
- Procedure: Pulmonary Function Testing
- Procedure: Electrocardiogram
- Procedure: Positron Emission Tomography
- Procedure: Magnetic Resonance Imaging
|
Observational
|
|
- University of Wisconsin, Madison
- National Institutes of Health (NIH)
|
Other / NIH |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
- Cardiac Substrate Utilization
- Global Oxidative Stress
- Fludeoxyglucose Uptake
|
40 |
All |
18 Years to 35 Years (Adult) |
NCT03245723 |
2017-0238
UL1TR000427 |
PET-MRI |
September 20, 2017 |
August 2020 |
August 2020 |
August 10, 2017 |
May 10, 2018 |
|
- UW Madison
Madison, Wisconsin, United States
|
|
| 45 |
NCT02450877 |
Recruiting |
A Study of Safety, Efficacy and Pharmacodynamics of Azacitidine in Children and Young Adults With Acute Myeloid Leukemia. |
|
- Drug: Azacitidine
- Other: Control Arm
|
Interventional
|
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Adverse Events (AEs)
- Dose-limiting toxicities (DLTs)
- Progression-free rate at Day 84 post randomization
- (and 16 more...)
|
80 |
All |
3 Months to 21 Years (Child, Adult) |
NCT02450877 |
AZA-AML-004 |
|
August 12, 2015 |
November 2, 2018 |
October 28, 2019 |
May 21, 2015 |
April 2, 2018 |
|
- Rigshospitalet
Copenhagen, Denmark - Charite Berlin
Berlin, Germany - Universitatsklinikum Essen
Essen, Germany - (and 5 more...)
|
|
| 46 |
NCT03423212 |
Recruiting |
Just Do You Program for Young Adults With Serious Mental IIlness |
- Depression
- Bipolar Disorder
- Psychosis
- Anxiety Disorders
|
- Behavioral: Just Do You
- Behavioral: Active Control
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- Adherence to PROS program
- Adherence to medication
- Just Do You group attendance
- Client Engagement in Child Protective Services Scale
|
195 |
All |
18 Years to 28 Years (Adult) |
NCT03423212 |
R34MH111861-01 |
|
January 31, 2018 |
October 31, 2019 |
October 31, 2019 |
February 6, 2018 |
March 29, 2018 |
|
- Mt Eden Personalized Recovery Oriented Services
New York, New York, United States
|
|
| 47 |
NCT03328286 |
Recruiting |
Improving Integration of Mentally Burdened Young Adults in the Labour Market |
|
- Behavioral: Weekly group meeting w/psychotherapist
|
Interventional
|
Not Applicable |
- Zurich University of Applied Sciences
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in Work Ability
- Change in Self-esteem
|
60 |
All |
16 Years to 25 Years (Child, Adult) |
NCT03328286 |
2017-00936 |
inklusiv |
August 15, 2017 |
July 31, 2019 |
July 31, 2019 |
November 1, 2017 |
November 6, 2017 |
|
- Toni Areal
Zürich, Switzerland
|
|
| 48 |
NCT03279055 |
Not yet recruiting |
Web-based Insomnia Treatment for Adolescent and Young Adult Cancer Survivors |
|
|
Interventional
|
Phase 3 |
- Dana-Farber Cancer Institute
- Alex's Lemonade Stand Foundation
|
Other / Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Insomnia symptoms
- Sleep efficiency
- Quality of life
- Daytime sleepiness
|
25 |
All |
14 Years to 25 Years (Child, Adult) |
NCT03279055 |
17-276 |
|
September 30, 2017 |
September 30, 2019 |
September 30, 2020 |
September 12, 2017 |
September 12, 2017 |
|
- Dana-Farber Cancer Institute
Boston, Massachusetts, United States
|
|
| 49 |
NCT02937051 |
Recruiting |
Effects of Cigar Flavors on Measures of Abuse Liability Among Young Adults |
|
- Other: Tobacco product administration and assessment
|
Interventional
|
Not Applicable |
- Virginia Commonwealth University
- National Institute on Drug Abuse (NIDA)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Participant)
- Primary Purpose: Basic Science
|
- Change in saliva nicotine concentration
- Change in breakpoint from two behavioral choice tasks (Cigarette Purchase Task, Multiple Choice Procedure)
- Change in Addiction Research Center Inventory subjective abuse liability
- (and 7 more...)
|
25 |
All |
18 Years to 21 Years (Adult) |
NCT02937051 |
HM20007848
R03DA043005 |
|
October 2016 |
June 2018 |
August 2018 |
October 18, 2016 |
July 24, 2017 |
|
- VCU Behavioral Health Research Laboratory
Richmond, Virginia, United States
|
|
| 50 |
NCT02842801 |
Recruiting |
Hip Manipulation in Young Adults With Groin, Lateral Hip or Buttock Pain |
|
|
Interventional
|
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Global Rating of Change (GROC) Scale
|
75 |
All |
18 Years to 40 Years (Adult) |
NCT02842801 |
18174 |
|
August 2015 |
August 2017 |
August 2017 |
July 25, 2016 |
July 25, 2016 |
|
- Texas Woman's University
Dallas, Texas, United States
|
|
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