23 studies found for:    Open Studies | "Shy-Drager Syndrome"
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Rank Status Study
1 Recruiting Oligomeric Alpha-synuclein in Multiple System Atrophy
Condition: Multiple System Atrophy (MSA)
Intervention:
2 Recruiting Cognitive and Behavioral Dysexecutive Syndrome in Multiple System Atrophy
Condition: Multiple System Atrophy
Interventions: Other: Clinical evaluation;   Other: neuropsychological battery test;   Other: MRI;   Other: Actigraphy
3 Recruiting Water and Sudafed in Autonomic Failure
Conditions: Shy-Drager Syndrome;   Multiple System Atrophy
Interventions: Drug: Pseudoephedrine + 480 ml water;   Drug: Pseudoephedrine + 50 ml water;   Other: Placebo + 480 ml water (optional);   Other: Placebo + 50 ml water (optional)
4 Recruiting Investigation of the Serotoninergic System in Multiple System Atrophy: a Positron Emission Tomography (PET) Study
Condition: Multiple System Atrophy
Interventions: Radiation: PET (Positron Emission Tomography) Study;   Other: Brain MRI (magnetic resonance imaging);   Drug: Fluoxétine / Placebo
5 Recruiting PROgressive Supranuclear Palsy CorTico-Basal Syndrome Multiple System Atrophy Longitudinal Study UK
Conditions: Progressive Supranuclear Palsy (PSP);   Corticobasal Degeneration;   Multiple System Atrophy (MSA)
Intervention:
6 Unknown  Fipamezole in Neurogenic Orthostatic Hypotension
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Parkinson's Disease;   Multiple System Atrophy
Interventions: Drug: Placebo;   Drug: Fipamezole
7 Recruiting Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA
Condition: Multiple System Atrophy
Interventions: Drug: L-Threo DOPS;   Drug: placebo
8 Recruiting Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure
Conditions: Autonomic Nervous System Disorders;   Pure Autonomic Failure;   Shy-Drager Syndrome;   Orthostatic Hypotension, Dysautonomic
Interventions: Drug: Angiotensin-(1-7);   Drug: Saline
9 Recruiting Biomarkers in Parkinsonian Syndromes
Conditions: Parkinsonian Syndromes;   Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Interventions: Other: CSF, blood and urine sampling;   Other: clinical measures of disease severity and progression
10 Not yet recruiting Unique Brainstem Biomarkers of Early Parkinson's Disease
Conditions: Parkinson's Disease;   Alzheimer's Disease;   Progressive Supranuclear Palsy;   Essential Tremor;   Multiple System Atrophy;   Drug Induced Parkinson's Disease;   Diffuse Lewy Body Disease;   Myasthenia Gravis
Interventions: Other: Electrical Brainstem Responses;   Other: Olfactory Tests;   Other: Visual Deprivation
11 Recruiting Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic
Conditions: Multiple System Atrophy;   Orthostatic Hypotension;   Supine Hypertension
Interventions: Drug: Trimethaphan;   Drug: Placebo
12 Recruiting Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease
Conditions: Parkinson Disease;   Multiple System Atrophy;   REM Sleep Behavior Disorder;   Pure Autonomic Failure;   Dementia With Lewy Bodies
Intervention:
13 Recruiting Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Syndromes
Conditions: Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy;   Vascular Parkinsonism
Intervention: Other: MRI exam of the brain
14 Recruiting Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure
Conditions: Orthostatic Hypotension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
Interventions: Other: Abdominal compression;   Other: Sham abdominal compression;   Drug: Placebo pill;   Drug: midodrine
15 Recruiting Local Heat Stress in Autonomic Failure Patients With Supine Hypertension
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
Interventions: Other: Passive heat stress;   Other: Control (non-heating)
16 Recruiting Magnetic Resonance Spectroscopy in Autonomic Failure
Conditions: Pure Autonomic Failure;   Multiple System Atrophy
Intervention: Procedure: Magnetic Resonance Spectroscopy Imaging
17 Recruiting Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: Losartan;   Drug: Captopril;   Drug: Placebo
18 Recruiting The Role of Endothelin in the Supine Hypertension of Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: BQ123;   Drug: Bq123;   Drug: Saline
19 Recruiting Norepinephrine Transporter Blockade, Autonomic Failure
Condition: Multiple System Atrophy (MSA)
Interventions: Drug: Atomexetine;   Drug: Placebo
20 Recruiting Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI)
Conditions: Parkinson's Disease (PD);   Parkinsonism;   Progressive Supranuclear Palsy (PSP);   Multiple System Atrophy (MSA)
Intervention:

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