383 studies found for:    Open Studies | "Sarcoma"
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1 Recruiting Dendritic Cell Vaccine With or Without Gemcitabine Pre-Treatment for Adults and Children With Sarcoma
Conditions: Sarcoma;   Soft Tissue Sarcoma;   Bone Sarcoma
Interventions: Biological: Dendritic Cells Vaccine;   Biological: Lysate of Tumor;   Drug: Gemcitabine;   Other: Imiquimod;   Procedure: Leukapheresis
2 Recruiting Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery
Conditions: Adult Fibrosarcoma;   Alveolar Soft Part Sarcoma;   Angiomatoid Fibrous Histiocytoma;   Atypical Fibroxanthoma;   Clear Cell Sarcoma of Soft Tissue;   Epithelioid Malignant Peripheral Nerve Sheath Tumor;   Epithelioid Sarcoma;   Extraskeletal Myxoid Chondrosarcoma;   Extraskeletal Osteosarcoma;   Fibrohistiocytic Neoplasm;   Glomus Tumor of the Skin;   Inflammatory Myofibroblastic Tumor;   Intimal Sarcoma;   Leiomyosarcoma;   Liposarcoma;   Low Grade Fibromyxoid Sarcoma;   Low Grade Myofibroblastic Sarcoma;   Malignant Cutaneous Granular Cell Tumor;   Malignant Peripheral Nerve Sheath Tumor;   Malignant Triton Tumor;   Mesenchymal Chondrosarcoma;   Myxofibrosarcoma;   Myxoid Chondrosarcoma;   Myxoinflammatory Fibroblastic Sarcoma;   Nerve Sheath Neoplasm;   PEComa;   Pericytic Neoplasm;   Plexiform Fibrohistiocytic Tumor;   Sclerosing Epithelioid Fibrosarcoma;   Stage IB Soft Tissue Sarcoma;   Stage IIB Soft Tissue Sarcoma;   Stage III Soft Tissue Sarcoma;   Stage IV Soft Tissue Sarcoma;   Synovial Sarcoma;   Undifferentiated (Embryonal) Sarcoma;   Undifferentiated High Grade Pleomorphic Sarcoma of Bone
Interventions: Drug: Doxorubicin Hydrochloride;   Drug: Ifosfamide;   Other: Laboratory Biomarker Analysis;   Drug: Pazopanib Hydrochloride;   Other: Pharmacological Study;   Radiation: Radiation Therapy;   Procedure: Therapeutic Conventional Surgery
3 Recruiting Trial of CMB305 and Atezolizumab in Patients With Sarcoma
Conditions: Sarcoma;   Myxoid/Round Cell Liposarcoma;   Synovial Sarcoma;   Metastatic Sarcoma;   Recurrent Adult Soft Tissue Sarcoma;   Locally Advanced Sarcoma;   Liposarcoma
Interventions: Biological: CMB305;   Biological: atezolizumab
4 Recruiting Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma
Conditions: Adult Alveolar Soft Part Sarcoma;   Adult Angiosarcoma;   Adult Desmoplastic Small Round Cell Tumor;   Adult Epithelioid Hemangioendothelioma;   Adult Epithelioid Sarcoma;   Adult Extraskeletal Myxoid Chondrosarcoma;   Adult Extraskeletal Osteosarcoma;   Adult Fibrosarcoma;   Adult Leiomyosarcoma;   Adult Liposarcoma;   Adult Malignant Mesenchymoma;   Adult Malignant Peripheral Nerve Sheath Tumor;   Adult Rhabdomyosarcoma;   Adult Synovial Sarcoma;   Adult Undifferentiated Pleomorphic Sarcoma;   Malignant Adult Hemangiopericytoma;   Recurrent Adult Soft Tissue Sarcoma;   Stage III Adult Soft Tissue Sarcoma;   Stage IV Adult Soft Tissue Sarcoma
Interventions: Drug: Gemcitabine Hydrochloride;   Other: Laboratory Biomarker Analysis;   Drug: Pazopanib Hydrochloride;   Other: Placebo
5 Recruiting Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma
Conditions: Sarcoma, Soft Tissue;   Soft Tissue Sarcoma;   Undifferentiated Pleomorphic Sarcoma;   Leiomyosarcoma;   Liposarcoma;   Synovial Sarcoma;   Myxofibrosarcoma;   Angiosarcoma;   Fibrosarcoma;   Malignant Peripheral Nerve Sheath Tumor;   Epithelioid Sarcoma
Interventions: Drug: Dexrazoxane;   Drug: Doxorubicin
6 Recruiting Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas
Conditions: Sarcoma, Bone;   Sarcoma, Soft Tissue;   Osteosarcoma;   Sarcoma, Ewing;   Rhabdomyosarcoma;   Non-rhabdomyosarcoma Soft-tissue Sarcoma
Intervention: Procedure: Diffusion Weighted Magnetic Resonance Imaging
7 Recruiting Pomalidomide for Kaposi Sarcoma in People With or Without HIV
Conditions: Kaposi Sarcoma;   Sarcoma, Kaposi
Intervention: Drug: Pomalidomide
8 Recruiting Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas
Conditions: Alveolar Soft Part Sarcoma;   Soft Tissue Sarcomas
Interventions: Drug: Axitinib;   Drug: Pembrolizumab;   Procedure: Blood Draw;   Procedure: Tumor Specimen Collection
9 Recruiting Phase II Multicentric Study of Digoxin Per os in Classic or Endemic Kaposi' s Sarcoma
Conditions: Kaposi' s Sarcoma;   Classic Kaposi' s Sarcoma;   Endemic Kaposi' s Sarcoma;   Lymph Angio Proliferations
Intervention: Drug: digoxin
10 Recruiting Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma
Conditions: High Grade Sarcoma;   Metastatic Leiomyosarcoma;   Metastatic Malignant Peripheral Nerve Sheath Tumor;   Metastatic Synovial Sarcoma;   Metastatic Undifferentiated Pleomorphic Sarcoma;   Myxofibrosarcoma;   Recurrent Leiomyosarcoma;   Recurrent Malignant Peripheral Nerve Sheath Tumor;   Recurrent Synovial Sarcoma;   Recurrent Undifferentiated Pleomorphic Sarcoma;   Uterine Corpus Leiomyosarcoma
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Pazopanib Hydrochloride;   Drug: Sapanisertib
11 Recruiting A Study of IMRT in Primary Bone and Soft Tissue Sarcoma
Conditions: Soft Tissue Sarcoma,;   Ewing Sarcoma;   Bone Sarcoma;   Chordoma
Intervention: Radiation: Intensity modulated radiotherapy (IMRT)
12 Recruiting Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
Conditions: Adult Rhabdomyosarcoma;   Childhood Desmoplastic Small Round Cell Tumor;   Chordoma;   Desmoid Tumor;   Metastatic Childhood Soft Tissue Sarcoma;   Nonmetastatic Childhood Soft Tissue Sarcoma;   Previously Treated Childhood Rhabdomyosarcoma;   Previously Untreated Childhood Rhabdomyosarcoma;   Recurrent Adult Soft Tissue Sarcoma;   Recurrent Childhood Rhabdomyosarcoma;   Recurrent Childhood Soft Tissue Sarcoma;   Stage I Adult Soft Tissue Sarcoma;   Stage II Adult Soft Tissue Sarcoma;   Stage III Adult Soft Tissue Sarcoma;   Stage IV Adult Soft Tissue Sarcoma
Interventions: Other: biologic sample preservation procedure;   Other: laboratory biomarker analysis
13 Recruiting Collecting and Storing Biological Samples From Patients With Ewing Sarcoma
Conditions: Askin Tumor;   Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Intervention: Other: laboratory biomarker analysis
14 Not yet recruiting DHEA in Synovial Sarcoma Patients
Conditions: Synovial Sarcoma;   Sarcoma, Synovial
Interventions: Drug: DHEA;   Other: FACT-67 validated survey
15 Recruiting Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI
Conditions: Bone Cancer;   Chondrosarcoma;   Ewing's Sarcoma;   Osteosarcoma;   Rhabdomyosarcoma;   Bone Necrosis;   Bone Sarcoma;   Osteomyelitis
Interventions: Drug: Feraheme;   Procedure: MR Scan
16 Recruiting Real-Time Contrast-Enhanced Ultrasonography and Shear Wave Elastography in Predicting Treatment Response in Patients With Soft Tissue Sarcoma
Conditions: Adult Soft Tissue Sarcoma;   Bone Sarcoma;   Retroperitoneal Sarcoma
Interventions: Procedure: Real-Time CEUS;   Procedure: SWE
17 Unknown  Bevacizumab and Radiation Therapy for Sarcomas
Conditions: Soft Tissue Sarcoma;   Fibrous Histiocytoma;   Liposarcoma;   Leiomyosarcoma;   Fibrosarcoma;   Synovial Sarcoma
Interventions: Drug: Bevacizumab;   Procedure: Radiation Therapy
18 Unknown  Study of Blood Samples From Patients With Ewing Sarcoma and Their Relatives
Condition: Sarcoma
Intervention: Other: genome-wide association study
19 Recruiting A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma
Conditions: Malignant Rhabdoid Tumors (MRT);   Rhabdoid Tumors of the Kidney (RTK);   Atypical Teratoid Rhabdoid Tumors (ATRT);   Selected Tumors With Rhabdoid Features;   Synovial Sarcoma;   INI1-negative Tumors;   Malignant Rhabdoid Tumor of Ovary;   Renal Medullary Carcinoma;   Epithelioid Sarcoma
Intervention: Drug: Tazemetostat
20 Recruiting Cabozantinib-s-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma
Conditions: Metastatic Ewing Sarcoma;   Metastatic Osteosarcoma;   Recurrent Ewing Sarcoma;   Recurrent Osteosarcoma;   Stage IVA Osteosarcoma;   Stage IVB Osteosarcoma
Interventions: Drug: Cabozantinib S-malate;   Other: Laboratory Biomarker Analysis

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