382 studies found for:    Open Studies | "Sarcoma"
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Participant Details
Rank Status Study
1 Recruiting Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcoma
Conditions: Neuroblastoma;   Ewings Sarcoma;   Osteogenic Sarcoma;   Rhabdomyosarcoma;   Synovial Sarcoma
Intervention: Biological: Autologous dendritic cell vaccine with adjuvant
2 Recruiting Bevacizumab, Chemotherapy and Valproic Acid in Advanced Sarcomas
Conditions: Sarcoma;   Soft Tissue Sarcoma;   Locally Advanced Sarcoma;   Unresectable Sarcoma;   Metastatic Sarcoma
Intervention: Drug: Bevacizumab, Gemcitabine, docetaxel and valproic acid
3 Recruiting Dendritic Cell Vaccine With or Without Gemcitabine Pre-Treatment for Adults and Children With Sarcoma
Conditions: Sarcoma;   Soft Tissue Sarcoma;   Bone Sarcoma
Interventions: Biological: Dendritic Cells Vaccine;   Biological: Lysate of Tumor;   Drug: Gemcitabine;   Other: Imiquimod;   Procedure: Leukapheresis
4 Recruiting Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery
Conditions: Adult Fibrosarcoma;   Alveolar Soft Part Sarcoma;   Angiomatoid Fibrous Histiocytoma;   Atypical Fibroxanthoma;   Clear Cell Sarcoma of Soft Tissue;   Epithelioid Malignant Peripheral Nerve Sheath Tumor;   Epithelioid Sarcoma;   Extraskeletal Myxoid Chondrosarcoma;   Extraskeletal Osteosarcoma;   Fibrohistiocytic Neoplasm;   Glomus Tumor of the Skin;   Inflammatory Myofibroblastic Tumor;   Intimal Sarcoma;   Leiomyosarcoma;   Liposarcoma;   Low Grade Fibromyxoid Sarcoma;   Low Grade Myofibroblastic Sarcoma;   Malignant Cutaneous Granular Cell Tumor;   Malignant Peripheral Nerve Sheath Tumor;   Malignant Triton Tumor;   Mesenchymal Chondrosarcoma;   Myxofibrosarcoma;   Myxoid Chondrosarcoma;   Myxoinflammatory Fibroblastic Sarcoma;   Nerve Sheath Neoplasm;   PEComa;   Pericytic Neoplasm;   Plexiform Fibrohistiocytic Tumor;   Sclerosing Epithelioid Fibrosarcoma;   Stage IB Soft Tissue Sarcoma;   Stage IIB Soft Tissue Sarcoma;   Stage III Soft Tissue Sarcoma;   Stage IV Soft Tissue Sarcoma;   Synovial Sarcoma;   Undifferentiated (Embryonal) Sarcoma;   Undifferentiated High Grade Pleomorphic Sarcoma of Bone
Interventions: Drug: Doxorubicin Hydrochloride;   Drug: Ifosfamide;   Other: Laboratory Biomarker Analysis;   Drug: Pazopanib Hydrochloride;   Other: Pharmacological Study;   Radiation: Radiation Therapy;   Procedure: Therapeutic Conventional Surgery
5 Recruiting Trial of CMB305 and Atezolizumab in Patients With Sarcoma
Conditions: Sarcoma;   Myxoid/Round Cell Liposarcoma;   Synovial Sarcoma;   Metastatic Sarcoma;   Recurrent Adult Soft Tissue Sarcoma;   Locally Advanced Sarcoma;   Liposarcoma
Interventions: Biological: CMB305;   Biological: atezolizumab
6 Recruiting Eurosarc Trial of Linsitinib in Advanced Ewing Sarcoma
Conditions: Relapsed Ewing Sarcoma;   Refractory Ewing Sarcoma
Intervention: Drug: Linsitinib
7 Recruiting Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma
Conditions: Adult Alveolar Soft Part Sarcoma;   Adult Angiosarcoma;   Adult Desmoplastic Small Round Cell Tumor;   Adult Epithelioid Hemangioendothelioma;   Adult Epithelioid Sarcoma;   Adult Extraskeletal Myxoid Chondrosarcoma;   Adult Extraskeletal Osteosarcoma;   Adult Fibrosarcoma;   Adult Leiomyosarcoma;   Adult Liposarcoma;   Adult Malignant Mesenchymoma;   Adult Malignant Peripheral Nerve Sheath Tumor;   Adult Rhabdomyosarcoma;   Adult Synovial Sarcoma;   Adult Undifferentiated Pleomorphic Sarcoma;   Malignant Adult Hemangiopericytoma;   Recurrent Adult Soft Tissue Sarcoma;   Stage III Adult Soft Tissue Sarcoma;   Stage IV Adult Soft Tissue Sarcoma
Interventions: Drug: Gemcitabine Hydrochloride;   Other: Laboratory Biomarker Analysis;   Drug: Pazopanib Hydrochloride;   Other: Placebo
8 Recruiting NY-ESO-1-specific T Cells in Treating Patients With Advanced NY-ESO-1-Expressing Sarcomas Receiving Palliative Radiation Therapy
Conditions: Mast Cell Sarcoma;   Ovarian Sarcoma;   Recurrent Adult Soft Tissue Sarcoma;   Recurrent Uterine Sarcoma;   Stage III Adult Soft Tissue Sarcoma;   Stage IIIA Uterine Sarcoma;   Stage IIIB Uterine Sarcoma;   Stage IIIC Uterine Sarcoma;   Stage IV Adult Soft Tissue Sarcoma;   Stage IVA Uterine Sarcoma;   Stage IVB Uterine Sarcoma
Interventions: Biological: Autologous NY-ESO-1-specific CD8-positive T Lymphocytes;   Radiation: palliative radiation therapy;   Other: laboratory biomarker analysis
9 Recruiting Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas
Conditions: Childhood Alveolar Soft-part Sarcoma;   Childhood Angiosarcoma;   Childhood Desmoplastic Small Round Cell Tumor;   Childhood Epithelioid Sarcoma;   Childhood Fibrosarcoma;   Childhood Leiomyosarcoma;   Childhood Liposarcoma;   Childhood Malignant Mesenchymoma;   Childhood Neurofibrosarcoma;   Childhood Synovial Sarcoma;   Chordoma;   Desmoid Tumor;   Metastatic Childhood Soft Tissue Sarcoma;   Nonmetastatic Childhood Soft Tissue Sarcoma;   Recurrent Childhood Soft Tissue Sarcoma
Intervention: Other: laboratory biomarker analysis
10 Not yet recruiting Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma
Conditions: Sarcoma, Soft Tissue;   Soft Tissue Sarcoma;   Undifferentiated Pleomorphic Sarcoma;   Leiomyosarcoma;   Liposarcoma;   Synovial Sarcoma;   Myxofibrosarcoma;   Angiosarcoma;   Fibrosarcoma;   Malignant Peripheral Nerve Sheath Tumor;   Epithelioid Sarcoma
Interventions: Drug: Dexrazoxane;   Drug: Doxorubicin
11 Recruiting Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas
Conditions: Sarcoma, Bone;   Sarcoma, Soft Tissue;   Osteosarcoma;   Sarcoma, Ewing;   Rhabdomyosarcoma;   Non-rhabdomyosarcoma Soft-tissue Sarcoma
Intervention: Procedure: Diffusion Weighted Magnetic Resonance Imaging
12 Recruiting Pomalidomide for Kaposi Sarcoma in People With or Without HIV
Conditions: Kaposi Sarcoma;   Sarcoma, Kaposi
Intervention: Drug: Pomalidomide
13 Recruiting Phase II Multicentric Study of Digoxin Per os in Classic or Endemic Kaposi' s Sarcoma
Conditions: Kaposi' s Sarcoma;   Classic Kaposi' s Sarcoma;   Endemic Kaposi' s Sarcoma;   Lymph Angio Proliferations
Intervention: Drug: digoxin
14 Not yet recruiting Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma
Conditions: High Grade Sarcoma;   Metastatic Leiomyosarcoma;   Metastatic Malignant Peripheral Nerve Sheath Tumor;   Metastatic Synovial Sarcoma;   Metastatic Undifferentiated Pleomorphic Sarcoma;   Myxofibrosarcoma;   Recurrent Leiomyosarcoma;   Recurrent Malignant Peripheral Nerve Sheath Tumor;   Recurrent Synovial Sarcoma;   Recurrent Undifferentiated Pleomorphic Sarcoma;   Uterine Corpus Leiomyosarcoma
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Pazopanib Hydrochloride;   Drug: TORC1/2 Inhibitor INK128
15 Recruiting Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
Conditions: Adult Supratentorial Primitive Neuroectodermal Tumor (PNET);   Childhood Supratentorial Primitive Neuroectodermal Tumor;   Ewing Sarcoma of Bone;   Extraosseous Ewing Sarcoma;   Extraosseous Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Peripheral Primitive Neuroectodermal Tumor of the Kidney;   Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions: Drug: vincristine sulfate;   Drug: doxorubicin hydrochloride;   Drug: cyclophosphamide;   Drug: ifosfamide;   Drug: etoposide;   Drug: topotecan hydrochloride;   Other: laboratory biomarker analysis
16 Not yet recruiting A Study of IMRT in Primary Bone and Soft Tissue Sarcoma
Conditions: Soft Tissue Sarcoma,;   Ewing Sarcoma;   Bone Sarcoma;   Chordoma
Intervention: Radiation: Intensity modulated radiotherapy (IMRT)
17 Recruiting NY-ESO-1 Specific T Cells After Cyclophosphamide in Treating Patients With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Conditions: Adult Synovial Sarcoma;   Myxoid/Round Cell Liposarcoma;   Recurrent Adult Soft Tissue Sarcoma;   Stage III Adult Soft Tissue Sarcoma;   Stage IV Adult Soft Tissue Sarcoma
Interventions: Biological: Autologous NY-ESO-1-specific CD8-positive T Lymphocytes;   Drug: Cyclophosphamide;   Other: Laboratory Biomarker Analysis
18 Recruiting Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic or Unresectable Sarcoma
Conditions: Recurrent Adult Soft Tissue Sarcoma;   Stage III Adult Soft Tissue Sarcoma;   Stage III Bone Sarcoma;   Stage IV Adult Soft Tissue Sarcoma;   Stage IVA Bone Sarcoma;   Stage IVB Bone Sarcoma
Interventions: Biological: Ipilimumab;   Other: Laboratory Biomarker Analysis;   Biological: Nivolumab;   Other: Quality-of-Life Assessment
19 Recruiting Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors
Conditions: Desmoplastic Small Round Cell Tumor;   Ewing Sarcoma of Bone or Soft Tissue;   Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Interventions: Drug: vincristine;   Drug: doxorubicin;   Drug: cyclophosphamide;   Drug: ifosfamide;   Drug: etoposide;   Drug: temozolomide;   Drug: temsirolimus;   Drug: bevacizumab;   Drug: sorafenib;   Procedure: surgery;   Radiation: radiation
20 Recruiting Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
Conditions: Adult Rhabdomyosarcoma;   Childhood Desmoplastic Small Round Cell Tumor;   Chordoma;   Desmoid Tumor;   Metastatic Childhood Soft Tissue Sarcoma;   Nonmetastatic Childhood Soft Tissue Sarcoma;   Previously Treated Childhood Rhabdomyosarcoma;   Previously Untreated Childhood Rhabdomyosarcoma;   Recurrent Adult Soft Tissue Sarcoma;   Recurrent Childhood Rhabdomyosarcoma;   Recurrent Childhood Soft Tissue Sarcoma;   Stage I Adult Soft Tissue Sarcoma;   Stage II Adult Soft Tissue Sarcoma;   Stage III Adult Soft Tissue Sarcoma;   Stage IV Adult Soft Tissue Sarcoma
Interventions: Other: biologic sample preservation procedure;   Other: laboratory biomarker analysis

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Indicates status has not been verified in more than two years