89 studies found for:    Open Studies | "Salivary Gland Diseases"
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Rank Status Study
21 Recruiting Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adults
Condition: Sialorrhea
Intervention: Drug: MYOBLOC
22 Recruiting UCB Proof of Concept Study in Patients With Primary Sjogren's Syndrome
Condition: Primary Sjogren's Syndrome
Interventions: Drug: UCB5857;   Drug: Placebo
23 Recruiting Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer
Condition: Radiation-Induced Xerostomia
Interventions: Other: Standard Oral Hygiene;   Other: Standard Oral Hygiene + True Acupuncture;   Other: Standard Oral Hygiene + Sham Acupuncture
24 Recruiting Study of LOXO-101 in Subjects With NTRK Fusion Positive Solid Tumors (NAVIGATE)
Conditions: Carcinoma, Non-Small-Cell Lung;   Thyroid Neoplasms;   Sarcoma;   Colorectal Neoplasms;   Salivary Gland Neoplasms;   Biliary Tract Neoplasms;   Brain Neoplasm, Primary;   Carcinoma, Ductal, Breast;   Melanoma;   Solid Tumors;   Glioblastoma;   Bile Duct Neoplasms;   Astrocytoma;   Head and Neck Squamous Cell Carcinoma;   Pontine Glioma
Intervention: Drug: LOXO-101
25 Recruiting Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK1/2/3, ROS1, or ALK Gene Rearrangements (Fusions)
Conditions: Breast Cancer;   Cholangiocarcinoma;   Colorectal Cancer;   Head and Neck Neoplasms;   Lymphoma, Large-Cell, Anaplastic;   Melanoma;   Neuroendocrine Tumors;   Non-Small Cell Lung Cancer;   Ovarian Cancer;   Pancreatic Cancer;   Papillary Thyroid Cancer;   Primary Brain Tumors;   Renal Cell Carcinoma;   Sarcomas;   Salivary Gland Cancers;   Adult Solid Tumor
Intervention: Drug: Entrectinib
26 Recruiting Pembrolizumab and Vorinostat in Treating Patients With Recurrent Squamous Cell Head and Neck Cancer or Salivary Gland Cancer That Is Metastatic and/or Cannot Be Removed by Surgery
Conditions: Head and Neck Squamous Cell Carcinoma;   Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma;   Recurrent Nasopharynx Carcinoma;   Recurrent Salivary Gland Carcinoma;   Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary;   Stage III Major Salivary Gland Carcinoma;   Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma;   Stage III Nasopharyngeal Carcinoma;   Stage IV Nasopharyngeal Carcinoma;   Stage IVA Major Salivary Gland Carcinoma;   Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma;   Stage IVB Major Salivary Gland Carcinoma;   Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma;   Stage IVC Major Salivary Gland Carcinoma;   Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma
Interventions: Other: Laboratory Biomarker Analysis;   Biological: Pembrolizumab;   Drug: Vorinostat
27 Recruiting Post-parotidectomy Facial Paresis: Intraoperative and Postoperative Factors
Conditions: Parotid Neoplasms;   Facial Paralysis
Intervention: Behavioral: Facial exercises
28 Recruiting A Phase III Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome
Condition: Dry Eye With Sjögren's Syndrome
Interventions: Drug: KCT-0809 ophthalmic solution;   Drug: Placebo
29 Recruiting An Extension Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome
Condition: Dry Eye With Sjögren's Syndrome
Intervention: Drug: KCT-0809 ophthalmic solution
30 Recruiting A Long-term Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome
Condition: Dry Eye With Sjögren's Syndrome
Intervention: Drug: KCT-0809 ophthalmic solution
31 Recruiting Acupuncture-Like Transcutaneous Electrical Nerve Stimulation in Treating Radiation-Induced Xerostomia in Patients With Head and Neck Cancer
Conditions: Head and Neck Carcinoma;   Xerostomia
Interventions: Other: Quality-of-Life Assessment;   Procedure: Transcutaneous Acupoint Electrical Stimulation
32 Recruiting A Phase II Study With Low-dose Recombinant Human IL-2 for the Treatment of Primary Sjögren's Syndrome
Condition: Primary Sjögren's Syndrome
Interventions: Drug: hrIL-2 active;   Drug: hrIL-2 placebo
33 Recruiting Pregnancy and Medically Assisted Conception in Rare Diseases
Conditions: Rheumatoid Arthritis;   Spondyloarthritis;   Psoriatic Arthritis;   Systemic Lupus Erythematosus;   Antiphospholipid Syndrome;   Sjogren Syndrome;   Scleroderma;   Myositis;   Vasculitis;   Mastocytosis;   Various Autoimmune and/or Systemic and/or Rare Diseases
Intervention:
34 Recruiting Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction
Conditions: Squamous Cell Head and Neck Cancer;   Radiation Induced Xerostomia;   Salivary Hypofunction
Intervention: Biological: AAV2hAQP1
35 Recruiting Sjögren's Biomarker Study
Conditions: Healthy;   Sjögren's Syndrome
Intervention:
36 Not yet recruiting Investigating the Role of Mucin and Mucin Glycosylating Enzymes in Nasopharyngeal Carcinoma and Salivary Gland Cancer and Their Correlation With Clinical Prognosis
Conditions: Salivary Gland Cancer;   Nasopharyngeal Carcinoma
Intervention:
37 Not yet recruiting Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson's Disease
Conditions: Sialorrhea;   Parkinson's Disease
Interventions: Drug: Glycopyrrolate;   Drug: Placebo
38 Not yet recruiting the Effect of HCG Treatment as a Cardiovascular Disease Morbidity Factor in Sjogren Syndrome Patients
Condition: Primary Sjogren Syndrome With Multisystem Involvement
Intervention: Other: Retrospective study
39 Recruiting Effect of Childhood Radioiodine Therapy on Salivary Function
Conditions: Xerostomia;   Hyperthyroidism;   Thyroid Cancer
Intervention: Other: Radioiodine
40 Not yet recruiting Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome
Condition: Sjogren's Syndrome
Interventions: Drug: Cyclosporin A;   Drug: Prednisone;   Drug: Placebo;   Drug: Calcium carbonate D

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Indicates status has not been verified in more than two years