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22 studies found for:    Open Studies | "Rhabdoid Tumor"
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Rank Status Study
1 Recruiting Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors
Conditions: Malignant Rhabdoid Tumor;   Atypical Teratoid Rhabdoid Tumor
Interventions: Drug: alisertib;   Drug: methotrexate;   Drug: cisplatin;   Drug: carboplatin;   Drug: cyclophosphamide;   Drug: etoposide;   Drug: topotecan;   Drug: vincristine;   Procedure: Surgical resection;   Radiation: Radiation therapy
2 Recruiting A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma
Conditions: Malignant Rhabdoid Tumors (MRT);   Rhabdoid Tumors of the Kidney (RTK);   Atypical Teratoid Rhabdoid Tumors (ATRT);   Selected Tumors With Rhabdoid Features;   Synovial Sarcoma;   INI1-negative Tumors;   Malignant Rhabdoid Tumor of Ovary;   Renal Medullary Carcinoma;   Epithelioid Sarcoma
Intervention: Drug: Tazemetostat
3 Recruiting Tazemetostat Rollover Study (TRuST): An Open-Label Rollover Study
Conditions: Diffuse Large B-cell Lymphoma;   Follicular Lymphoma;   Malignant Rhabdoid Tumors (MRT);   Rhabdoid Tumors of the Kidney (RTK);   Atypical Teratoid Rhabdoid Tumors (ATRT);   Synovial Sarcoma;   Epitheliod Sarcoma;   Mesothelioma;   Advanced Solid Tumors
Intervention: Drug: Tazemetostat
4 Recruiting A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma
Conditions: Rhabdoid Tumors;   INI1-negative Tumors;   Synovial Sarcoma;   Malignant Rhabdoid Tumor of Ovary
Intervention: Drug: Tazemetostat
5 Not yet recruiting Phase II Pediatric Study With Dabrafenib in HGG Patients
Conditions: Anaplastic Astrocytoma;   Glioblastoma;   Giant Cell Glioblastoma;   Gliosarcoma;   Anaplastic Oligodendroglioma;   Anaplastic Oligoastrocytoma;   Anaplastic Ependymoma;   Choroid Plexus Carcinoma;   Anaplastic Ganglioglioma;   Pineal Parenchymal Tumor;   Pineoblastoma;   Medulloblastoma;   PNET;   Rhabdoid Tumor;   Perineurioma;   MPNST;   Malignant Meningloma;   Anaplastic Hemangiopericytoma
Intervention: Drug: dabrafenib
6 Recruiting Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors
Conditions: Retinoblastoma;   Clear Cell Sarcoma;   Renal Cell Carcinoma;   Rhabdoid Tumor;   Wilms Tumor;   Hepatoblastoma;   Neuroblastoma;   Germ Cell Tumors;   Ewings Sarcoma;   Non-rhabdomyosarcoma Soft Tissue Sarcoma;   Osteosarcoma;   Rhabdomyosarcoma
Interventions: Drug: Simvastatin;   Drug: Cyclophosphamide;   Drug: Topotecan;   Drug: Myeloid growth factor
7 Recruiting A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas
Conditions: Ewing Sarcoma;   Gastrointestinal Tumor;   Germ Cell Tumor;   Hepatic Tumor;   Lymphoma;   Wilms Tumor;   Rhabdoid Tumor;   Clear Cell Carcinoma;   Renal Cell Carcinoma;   Melanoma;   Neuroblastoma;   Rhabdomyosarcoma;   Non-rhabdomyosarcoma
Interventions: Drug: alemtuzumab;   Drug: fludarabine;   Drug: sirolimus;   Drug: Busulfan;   Drug: melphalan;   Biological: stem cells
8 Recruiting Study of Kidney Tumors in Younger Patients
Conditions: Clear Cell Sarcoma of the Kidney;   Congenital Mesoblastic Nephroma;   Diffuse Hyperplastic Perilobar Nephroblastomatosis;   Rhabdoid Tumor of the Kidney;   Stage I Renal Cell Cancer;   Stage I Wilms Tumor;   Stage II Renal Cell Cancer;   Stage II Wilms Tumor;   Stage III Renal Cell Cancer;   Stage III Wilms Tumor;   Stage IV Renal Cell Cancer;   Stage IV Wilms Tumor;   Stage V Wilms Tumor
Interventions: Other: laboratory biomarker analysis;   Other: cytology specimen collection procedure
9 Recruiting Molecular-Guided Therapy for Childhood Cancer
Conditions: Neuroblastoma;   Medulloblastoma;   Glioma;   Ependymoma;   Choroid Plexus Neoplasms;   Craniopharyngioma;   Dysembryoplastic Neuroepithelial Tumor;   Meningioma;   Primitive Neuroectodermal Tumors (PNETs);   Germ Cell Tumors;   Rhabdomyosarcoma;   Non-rhabdomyosarcoma;   Ewings Sarcoma;   Osteosarcoma;   Wilms Tumor;   Renal Cell Carcinoma;   Malignant Rhabdoid Tumor;   Clear Cell Sarcoma;   Liver Tumors
Intervention: Device: Guided Therapy
10 Recruiting Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors
Conditions: Diffuse Intrinsic Pontine Glioma;   Brain Tumor, Recurrent;   Solid Tumor, Recurrent;   Neuroblastoma, Recurrent, Refractory;   Ewing Sarcoma, Recurrent, Refractory;   Rhabdomyosarcoma, Recurrent, Refractory;   Osteosarcoma, Recurrent, Refractory;   Rhabdoid Tumor, Recurrent, Refractory
Intervention: Drug: Abemaciclib
11 Recruiting Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
Conditions: Ewing's Family Tumors;   Renal Tumors;   Hepatoblastoma;   Rhabdomyosarcoma;   Soft Tissue Sarcoma;   Primary Malignant Brain Neoplasms;   Retinoblastoma;   Medulloblastoma;   Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET);   Atypical Teratoid/Rhabdoid Tumor (AT/RT);   CNS Tumors;   Germ Cell Tumors
Interventions: Drug: Ifosfamide;   Drug: Etoposide;   Drug: Mesna;   Biological: G-CSF;   Drug: Busulfan;   Drug: Melphalan;   Drug: Thiotepa;   Biological: Autologous stem cell infusion;   Radiation: Radiation;   Drug: Carboplatin;   Drug: Paclitaxel;   Procedure: Leukapheresis
12 Recruiting Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors
Conditions: Recurrent Childhood Medulloblastoma;   Recurrent Childhood Ependymoma;   Childhood Atypical Teratoid/Rhabdoid Tumor;   Embryonal Tumor With Abundant Neuropil and True Rosettes;   Metastatic Malignant Neoplasm to the Leptomeninges
Interventions: Drug: Intra thecal methotrexate;   Drug: topotecan;   Drug: cyclophosphamide
13 Recruiting Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Recurrent or Refractory Brain Tumors
Conditions: Childhood Astrocytoma;   Childhood Atypical Teratoid/Rhabdoid Tumor;   Diffuse Intrinsic Pontine Glioma;   Glioma;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Neoplasm;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Medulloblastoma;   Recurrent Primitive Neuroectodermal Tumor;   Refractory Brain Neoplasm
Interventions: Other: Laboratory Biomarker Analysis;   Biological: Sargramostim;   Biological: Wild-type Reovirus
14 Recruiting Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors
Conditions: Adult Central Nervous System Germ Cell Tumor;   Adult Ependymoblastoma;   Adult Medulloblastoma;   Adult Pineoblastoma;   Adult Supratentorial Primitive Neuroectodermal Tumor;   Childhood Atypical Teratoid/Rhabdoid Tumor;   Childhood Central Nervous System Germ Cell Tumor;   Childhood Ependymoblastoma;   Medulloepithelioma;   Ototoxicity;   Recurrent Adult Brain Neoplasm;   Recurrent Childhood Central Nervous System Embryonal Neoplasm;   Recurrent Childhood Malignant Germ Cell Tumor;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Pineoblastoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions: Drug: Carboplatin;   Drug: Mannitol;   Drug: Melphalan;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Drug: Sodium Thiosulfate
15 Recruiting Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor;   Childhood Central Nervous System Germ Cell Tumor;   Childhood Choroid Plexus Tumor;   Childhood Craniopharyngioma;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Oligodendroglioma;   Childhood Supratentorial Ependymoma;   Newly Diagnosed Childhood Ependymoma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma
Intervention: Other: cytology specimen collection procedure
16 Recruiting Study of Stored Tumor Samples in Young Patients With Brain Tumors
Condition: Brain and Central Nervous System Tumors
Intervention:
17 Recruiting Collecting and Storing Tissue From Young Patients With Cancer
Condition: Cancer
Interventions: Genetic: DNA analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: biologic sample preservation procedure;   Other: flow cytometry;   Other: laboratory biomarker analysis
18 Recruiting HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors
Condition: Supratentorial Neoplasms, Malignant
Intervention: Biological: G207
19 Unknown  Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom
Conditions: Bladder Cancer;   Brain and Central Nervous System Tumors;   Esophageal Cancer;   Intraocular Melanoma;   Kidney Cancer;   Lymphoma;   Melanoma (Skin);   Pancreatic Cancer;   Transitional Cell Cancer of the Renal Pelvis and Ureter
Interventions: Genetic: DNA analysis;   Genetic: polymorphism analysis;   Other: laboratory biomarker analysis;   Other: questionnaire administration
20 Recruiting Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: Induction Chemotherapy;   Drug: Low-Risk Therapy;   Drug: High-Risk Therapy;   Drug: Intermediate-Risk Therapy

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