207 studies found for:    Open Studies | "Rectal Neoplasms"
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21 Recruiting Phase III Study Comparing, Efficacy and Safety of a Boost (CXB or EBRT) in Combination With Neoadjuvant Chemoradiotherapy for Early Rectal Adenocarcinoma
Condition: Rectal Neoplasms
Interventions: Radiation: 3D conformal EBRT;   Device: Contact X-ray brachytherapy 50 kV;   Drug: Capecitabine
22 Recruiting Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer
Conditions: Rectal Neoplasms;   Adenocarcinoma;   Carcinoma
Interventions: Drug: Capecitabine;   Drug: Metformin;   Radiation: Radiotherapy;   Drug: Placebo
23 Not yet recruiting Timing of Rectal Cancer Resection After Preoperative Chemoradiotherapy
Condition: Rectal Neoplasms
Intervention: Other: Extended Timing
24 Not yet recruiting Prediction of Response to Neoadjuvant Therapy in Rectal Cancer
Condition: Rectal Neoplasms
Intervention: Device: PET-CT Scan
25 Recruiting Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer
Conditions: Rectal Neoplasms;   Rectal Cancer Stage II;   Rectal Cancer Stage III
Interventions: Drug: Induction Chemotherapy arm A;   Radiation: Radiation arm A;   Radiation: Radiation arm B;   Drug: Chemotherapy arm B;   Procedure: Surgery
26 Recruiting Neoadjuvant Chemotherapy Alone Versus Preoperative Chemoradiation for Locally Advanced Rectal Cancer Patients
Condition: Rectal Neoplasms
Interventions: Drug: Oxaliplatin;   Drug: capecitabine;   Radiation: Radiation
27 Recruiting Functional Outcome of Organ Preservation After Neo-adjuvant Chemo Radiation for Rectal Cancer
Condition: Rectal Neoplasms
Interventions: Other: Questionnaires for the evaluation of Quality of Life;   Other: Manometry
28 Recruiting Predicting RadIotherapy ReSponse of Rectal Cancer With MRI and PET
Condition: Rectal Neoplasms
Interventions: Other: Early MRI and PET/CT - 2 weeks after commencing chemo/RT;   Other: Late MRI and PET/CT 6 weeks post chemo/RT
29 Recruiting Selinexor Combined With Standard Chemoradiation as Neoadjuvant Treatment in Locally Advanced Rectal Cancer
Condition: Rectal Neoplasms
Interventions: Radiation: standard dose pelvic radiation therapy;   Drug: standard dose capecitabine;   Drug: dose-escalated selinexor treatment
30 Recruiting Gene Expression and FDG PET/MRI in Evaluating Treatment Response in Patients With Locally Advanced Rectal Cancer Undergoing Chemotherapy and Radiation Therapy Before Surgery
Condition: Rectal Neoplasms
Interventions: Radiation: fludeoxyglucose F 18;   Device: positron emission tomography;   Device: magnetic resonance imaging;   Other: laboratory biomarker analysis
31 Not yet recruiting Use of One Kind of Controllable Tube Ileostomy in the Low Rectal Cancer
Conditions: Rectal Neoplasms;   Low Anterior Resection
Interventions: Device: Low anterior resection;   Device: tube ileostomy;   Device: loop ileostomy;   Device: accept reversal operation;   Device: remove the tube ileostomy
32 Recruiting Genetic Profile on Predicting Sensibility of Preoperative Chemoradiotherapy on Locally Advanced Rectal Carcinoma
Condition: Rectal Neoplasms
Intervention: Radiation: preoperative concurrent chemoradiation
33 Recruiting Functional MRI of Hypoxia-mediated Rectal Cancer Aggressiveness
Conditions: Rectal Diseases;   Rectal Neoplasms;   Gastrointestinal Diseases;   Gastrointestinal Neoplasms
Intervention: Procedure: new functional magnetic resonance imaging (MRI) protocols
34 Recruiting Maintenance Chemotherapy After Neoadjuvant Chemoradiation Therapy for Distal Rectal Cancer
Condition: Rectal Neoplasms
Interventions: Drug: 5FU/Leucovorin;   Radiation: external beam photon radiation
35 Recruiting Effective Study of Preoperative Short-course Radiotherapy for the Advanced Resectable Rectal Cancer
Condition: Rectal Neoplasms
Intervention: Radiation: preoperative short-course radiotherapy
36 Recruiting Adjuvant Treatment of Concurrent RT and CAPOX or Capecitabine Alone for Stage II and III Rectal Cancer
Condition: Rectal Neoplasms
Intervention:
37 Unknown  XELOX+Bevacizumab Followed by Capecitabine+Bevacizumab+Radiotherapy as Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma
Conditions: Rectal Neoplasms;   Locally Advanced Rectal Adenocarcinoma
Intervention: Drug: bevacizumab
38 Unknown  Anterior Perineal Plane for Ultra Low Anterior Resection of the Rectum
Conditions: Rectal Neoplasms;   Colitis, Ischemic;   Colitis, Ulcerative
Interventions: Procedure: Standard abdominal approach for rectal excision;   Procedure: APPEAR Procedure;   Procedure: Proctectomy
39 Recruiting Endoscopic Posterior Mesorectal Resection in T1 Rectal Cancer
Condition: Rectal Neoplasms
Intervention: Procedure: endoscopic posterior mesorectal resection
40 Unknown  Mesorectal Excision (ME) Versus ME With Lateral Node Dissection for Stage II, III Lower Rectal Cancer (JCOG0212)
Condition: Rectal Neoplasms
Interventions: Procedure: Mesorectal excision with lateral lymph node dissection;   Procedure: Mesorectal excision without lateral lymph node excision

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Indicates status has not been verified in more than two years