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145 studies found for:    Open Studies | "Protozoan Infections"
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Rank Status Study
21 Recruiting A Safety and Efficacy Study of R21 +/- ChAd63/MVA ME-TRAP
Condition: Malaria
Interventions: Biological: 10 µg R21/ 50 µg Matrix M1;   Biological: 50 µg R21/ 50 µg Matrix M1;   Biological: ChAd63 ME-TRAP;   Biological: MVA ME-TRAP;   Drug: Paracetamol;   Drug: Riamet;   Drug: Cyclizine;   Drug: Topical antihistamine
22 Recruiting Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers, Study 1
Condition: Malaria
Intervention: Drug: Primaquine, R-Primaquine, S-Primaquine, SR Primaquine
23 Recruiting Prevalence Survey of Plasmodium Falciparum Antimalarial Drug Resistance Markers
Condition: Plasmodium Falciparum
Intervention:
24 Not yet recruiting MMV390048 POC in Patients With P. Vivax and P. Falciparum Malaria
Condition: Malaria
Intervention: Drug: MMV390048
25 Recruiting RHOST-cRCT, Reactive Household-based Self-administered Treatment Against Residual Malaria Transmission
Condition: Malaria
Intervention: Biological: dihydroartemisinin-piperaquine
26 Not yet recruiting G6PD Assessment Before Primaquine for Radical Treatment of Vivax Malaria
Condition: Vivax Malaria
Interventions: Drug: Chloroquine;   Drug: Primaquine 0.25 mg/kg/day;   Drug: Primaquine 0.75 mg/kg weekly
27 Recruiting SJ733 Induced Blood Stage Malaria Challenge Study
Condition: Plasmodium Falciparum Malaria
Intervention: Drug: (+)-SJ000557733
28 Recruiting Safety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea.
Condition: Malaria
Interventions: Biological: PfSPZ Vaccine;   Biological: PfSPZ Challenge (for CHMI);   Other: Normal Saline;   Biological: PfSPZ Challenge (for PfSPZ-CVac)
29 Recruiting Controlled Human Malaria Infection Model for Evaluation of Transmission‐Blocking Interventions - Study 1
Condition: Malaria
Interventions: Drug: Sulfadoxine-pyrimethamine (low dose);   Drug: Piperaquine (low dose);   Drug: Sulfadoxine-pyrimethamine (high dose);   Drug: Piperaquine (high dose);   Biological: malaria challenge infection, P. falciparum 3D7;   Drug: Atovaquone-proguanil
30 Not yet recruiting Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria
Condition: Malaria, Vivax
Interventions: Drug: Tafenoquine;   Drug: Matched-Placebo for Tafenoquine;   Drug: Primaquine;   Drug: Matched-Placebo for Primaquine;   Drug: Dihydroartemisinin-piperaquine (DHA-PQP);   Drug: ACT plus PQ (Rescue medication);   Drug: PQ (End of study treatment)
31 Recruiting Child Follow-up Until 2 Years
Conditions: Malaria;   Pregnancy
Intervention:
32 Recruiting Prevention of Malaria in HIV-uninfected Pregnant Women and Infants
Condition: Malaria
Interventions: Drug: Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy;   Drug: Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy
33 Not yet recruiting A Randomized Controlled Trial on Malaria Primaquine Treatment in Timika, Indonesia (TRIPI)
Condition: Uncomplicated Malaria
Interventions: Drug: PQ supervised;   Drug: PQ unsupervised
34 Recruiting PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States
Condition: Plasmodium Falciparum Infection
Interventions: Drug: Chloroquine;   Biological: PfSPZ;   Other: Placebo
35 Recruiting Assessing the Effect of Neglected Tropical Diseases on Plasmodium Falciparum Transmission in an Area of Co-endemicity
Condition: Malaria Transmission
Interventions: Other: Pre-treatment follow up;   Other: S. haematobium treatment;   Other: Post treatment follow up;   Other: Olfactometer experiment
36 Recruiting Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA)
Condition: Malaria
Intervention: Biological: Plasmodium falciparum sporozoite (PfSPZ)
37 Recruiting Sequential Optimization of Dose and Schedule of PfSPZ Vaccine
Condition: Malaria
Interventions: Biological: PfSPZ Vaccine;   Biological: PfSPZ Challenge (NF54);   Biological: PfSPZ Challenge (7G8);   Other: Normal saline
38 Not yet recruiting Methylene Blue Against Vivax Malaria in Ethiopia
Condition: Vivax Malaria
Interventions: Drug: Artemeter-Lumefantrine and MB (combination therapy);   Drug: Artemeter-Lumefantrine (combination therapy);   Drug: Artemeter-Lumefantrine and Primaquine (combination therapy)
39 Recruiting Rosiglitazone Adjunctive Therapy for Severe Malaria in Children
Condition: Malaria
Interventions: Drug: Rosiglitazone;   Drug: Placebo
40 Recruiting Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living in Kenya
Condition: Malaria
Interventions: Biological: PfSPZ Vaccine;   Other: Normal Saline

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Study has passed its completion date and status has not been verified in more than two years.