141 studies found for:    Open Studies | "Protozoan Infections"
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Rank Status Study
21 Recruiting Safety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea.
Condition: Malaria
Interventions: Biological: PfSPZ Vaccine;   Biological: PfSPZ Challenge (for CHMI);   Other: Normal Saline;   Biological: PfSPZ Challenge (for PfSPZ-CVac)
22 Recruiting Methylene Blue Against Falciparum Malaria in Burkina Faso
Condition: Malaria, Falciparum
Interventions: Drug: Methylene Blue;   Drug: Primaquine
23 Recruiting Controlled Human Malaria Infection Model for Evaluation of Transmission‐Blocking Interventions - Study 1
Condition: Malaria
Interventions: Drug: Sulfadoxine-pyrimethamine (low dose);   Drug: Piperaquine (low dose);   Drug: Sulfadoxine-pyrimethamine (high dose);   Drug: Piperaquine (high dose);   Biological: malaria challenge infection, P. falciparum 3D7;   Drug: Atovaquone-proguanil
24 Not yet recruiting Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria
Condition: Malaria, Vivax
Interventions: Drug: Tafenoquine;   Drug: Matched-Placebo for Tafenoquine;   Drug: Primaquine;   Drug: Matched-Placebo for Primaquine;   Drug: Dihydroartemisinin-piperaquine (DHA-PQP);   Drug: ACT plus PQ (Rescue medication);   Drug: PQ (End of study treatment)
25 Recruiting Child Follow-up Until 2 Years
Conditions: Malaria;   Pregnancy
Intervention:
26 Recruiting Prevention of Malaria in HIV-uninfected Pregnant Women and Infants
Condition: Malaria
Interventions: Drug: Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy;   Drug: Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy
27 Not yet recruiting Diagnostic Utility of Volatile Organic Compounds in Human Breath for Acute Clinical Malaria in Ethiopia
Condition: Malaria
Intervention:
28 Recruiting Prevention of Malaria With Dihydroartemisinine + Piperaquine for Forest Rangers
Condition: Malaria
Interventions: Drug: Arterakine (DHA/piperaquine);   Drug: Placebo
29 Not yet recruiting A Randomized Controlled Trial on Malaria Primaquine Treatment in Timika, Indonesia (TRIPI)
Condition: Uncomplicated Malaria
Interventions: Drug: PQ supervised;   Drug: PQ unsupervised
30 Recruiting PfSPZ Challenge in Non-immune Adults in Baltimore, USA
Condition: Plasmodium Falciparum Infection
Interventions: Biological: PfSPZ (NF54);   Biological: PfSPZ (7G8)
31 Recruiting PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States
Condition: Plasmodium Falciparum Infection
Interventions: Drug: Chloroquine;   Other: Placebo;   Biological: PfSPZ
32 Recruiting Assessing the Effect of Neglected Tropical Diseases on Plasmodium Falciparum Transmission in an Area of Co-endemicity
Condition: Malaria Transmission
Interventions: Other: Pre-treatment follow up;   Other: S. haematobium treatment;   Other: Post treatment follow up;   Other: Olfactometer experiment
33 Recruiting Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA)
Condition: Malaria
Intervention: Biological: Plasmodium falciparum sporozoite (PfSPZ)
34 Recruiting Effectiveness of Mass Drug Administration for Reducing Seasonal Malaria Transmission in Zanzibar
Conditions: Malaria;   Plasmodium Infections
Intervention: Drug: MDA with DHAp and SLD Primaquine
35 Recruiting Sequential Optimization of Dose and Schedule of PfSPZ Vaccine
Condition: Malaria
Interventions: Biological: PfSPZ Vaccine;   Biological: PfSPZ Challenge (NF54);   Biological: PfSPZ Challenge (7G8);   Other: Normal saline
36 Not yet recruiting Low Resource Diagnostics Development Cohort - VZNIGHT
Condition: Malaria
Intervention: Other: No Intervention / Not Applicable
37 Not yet recruiting Methylene Blue Against Vivax Malaria in Ethiopia
Condition: Vivax Malaria
Interventions: Drug: Artemeter-Lumefantrine and MB (combination therapy);   Drug: Artemeter-Lumefantrine (combination therapy);   Drug: Artemeter-Lumefantrine and Primaquine (combination therapy)
38 Recruiting Rosiglitazone Adjunctive Therapy for Severe Malaria in Children
Condition: Malaria
Interventions: Drug: Rosiglitazone;   Drug: Placebo
39 Recruiting Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living in Kenya
Condition: Malaria
Interventions: Biological: PfSPZ Vaccine;   Other: Normal Saline
40 Recruiting Optimizing Sysmex Technology as an Innovative Tool to Differentiate Between Malaria (PALUdism) and BACterial Infections in a Malaria Endemic Region
Condition: Tropical Infectious Diseases
Intervention: Other: None, treatment as actual best practice

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Study has passed its completion date and status has not been verified in more than two years.