68 studies found for:    Open Studies | "Pleural Effusion"
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Rank Status Study
21 Not yet recruiting Recombinant Adenoviral Human p53 Gene in Treatment of Malignant Pleural Effusion
Condition: Malignant Pleural Effusion
Interventions: Drug: rAdp53;   Drug: Cisplatin;   Drug: rAdp53 plus cisplatin
22 Not yet recruiting Intrapleural Bevacizumab After Pleural Drainage in the Context of Breast Cancer
Conditions: Pleural Effusion, Malignant;   Breast Cancer
Intervention: Drug: Bevacizumab
23 Recruiting Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions
Condition: Loculated or Non-draining Malignant Pleural Effusions
Intervention: Drug: Combination TISSUE PLASMINOGEN ACTIVATOR (TPA) AND DORNASE ALFA (DNASE)
24 Unknown  A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis
Conditions: Malignant Pleural Effusions;   Recurrent Pleural Effusions;   Primary Spontaneous Pneumothorax;   Secondary Spontaneous Pneumothorax
Intervention: Procedure: Pleurodesis with either talc or iodopovidone
25 Recruiting Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer
Conditions: Non-small Cell Lung Cancer;   Malignant Pleural Effusion
Intervention: Drug: Bevacizumab
26 Recruiting Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy
Conditions: Pleural Effusion;   Pleurisy;   Empyema
Interventions: Drug: Cefazolin;   Other: saline
27 Recruiting Pathophysiological Effects of Intrapleural Pressure Changes During Therapeutic Thoracentesis
Conditions: Pleural Effusion;   Exudative Pleuritis
Interventions: Procedure: Therapeutic thoracentesis;   Device: Pleural catheter;   Device: Pleural manometer
28 Recruiting Pleural and Pericardial Effusion Following Open Heart Surgery
Conditions: Heart Disease;   Pleural Effusion;   Pericardial Effusion
Intervention: Procedure: pleuracentesis
29 Recruiting Tubeless Versus Standard Upper Pole Percutaneous Nephrolithotomy
Conditions: Pleural Effusion;   Pain
Interventions: Device: Double J stent  without nephrostomy;   Device: nephrostomy tube and double J stent
30 Recruiting A Feasibility and Safety Study of the Use of a Dedicated Ballooned Intercostal Drain
Condition: Pleural Effusion
Intervention: Device: Balloon-tipped intercostal drain
31 Recruiting Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative Study
Conditions: Pleural Effusion;   Pleural Diseases
Intervention: Device: cryobiopsy (Autoclavable cryoprobe 20416-032 (ERBE, Germany) Flexible FB-55CD-1 Olympus forceps
32 Unknown  Angiogenic Cytokines and Fibrinolytic Activity in Parapneumonic Effusions
Condition: Pleural Effusion
Intervention: Device: pleural pigtail drainage
33 Unknown  Detection of EGFR Mutation in Malignant Pleural Effusion of Lung Cancer Patients and Cancer Cell Lines Establishment
Condition: NSCLC
Intervention: Other: cancer cell lines establishment
34 Recruiting Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma
Condition: Lung Cancer
Intervention: Biological: GL-ONC1
35 Unknown  Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural Effusion
Condition: Metastatic Cancer
Interventions: Drug: ibuprofen;   Drug: morphine sulfate;   Procedure: management of therapy complications;   Procedure: pleurodesis
36 Recruiting Genetic Sequencing-Informed Targeted Therapy in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer
Conditions: Malignant Pericardial Effusion;   Malignant Pleural Effusion;   Recurrent Non-small Cell Lung Cancer;   Stage IIIB Non-small Cell Lung Cancer;   Stage IV Non-small Cell Lung Cancer
Interventions: Other: cytology specimen collection procedure;   Procedure: therapeutic procedure;   Drug: targeted therapy;   Other: laboratory biomarker analysis
37 Recruiting Metformin Hydrochloride and Combination Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Conditions: Brenner Tumor;   Malignant Ascites;   Malignant Pleural Effusion;   Ovarian Clear Cell Cystadenocarcinoma;   Ovarian Endometrioid Adenocarcinoma;   Ovarian Mixed Epithelial Carcinoma;   Ovarian Serous Cystadenocarcinoma;   Ovarian Undifferentiated Adenocarcinoma;   Recurrent Fallopian Tube Cancer;   Recurrent Ovarian Epithelial Cancer;   Recurrent Ovarian Germ Cell Tumor;   Recurrent Primary Peritoneal Cavity Cancer;   Stage IIIA Fallopian Tube Cancer;   Stage IIIA Ovarian Epithelial Cancer;   Stage IIIA Ovarian Germ Cell Tumor;   Stage IIIA Primary Peritoneal Cavity Cancer;   Stage IIIB Fallopian Tube Cancer;   Stage IIIB Ovarian Epithelial Cancer;   Stage IIIB Ovarian Germ Cell Tumor;   Stage IIIB Primary Peritoneal Cavity Cancer;   Stage IIIC Fallopian Tube Cancer;   Stage IIIC Ovarian Epithelial Cancer;   Stage IIIC Ovarian Germ Cell Tumor;   Stage IIIC Primary Peritoneal Cavity Cancer;   Stage IV Fallopian Tube Cancer;   Stage IV Ovarian Epithelial Cancer;   Stage IV Ovarian Germ Cell Tumor;   Stage IV Primary Peritoneal Cavity Cancer
Interventions: Drug: paclitaxel;   Drug: carboplatin;   Drug: docetaxel;   Drug: metformin hydrochloride;   Drug: placebo;   Other: laboratory biomarker analysis
38 Recruiting Biomarker Levels During Indwelling Pleural cAtheter Sample Testing
Condition: Malignant Pleural Effusions
Intervention:
39 Recruiting Yield of Cryoprobe vs Flexible Forceps Pleural Biopsy
Conditions: Pleural Effusion;   Pleurisy;   Tuberculosis;   Metastatic Malignancy
Interventions: Device: Cryoprobe pleural biopsy first;   Device: Flexible forceps biopsy first
40 Not yet recruiting Exploration of the Pleural Cavity Using a fleXible endoscoPe
Condition: Pleural Effusion
Interventions: Device: flexible video endoscope;   Device: video-rigid thoracoscope

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Indicates status has not been verified in more than two years