94 studies found for:    Open Studies | "Pleural Diseases"
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Rank Status Study
1 Recruiting Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin
Conditions: Malignant Pleural Disease;   Mesothelioma;   Metastases;   Lung Cancer;   Breast Cancer
Interventions: Genetic: iCasp9M28z T cell infusions;   Drug: cyclophosphamide
2 Recruiting Impact of Respiratory Physiotherapy in the Management of Infectious Pleural Effusion
Conditions: Pleural Diseases;   Infection
Intervention: Other: Chest physiotherapy
3 Recruiting Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative Study
Conditions: Pleural Effusion;   Pleural Diseases
Intervention: Device: cryobiopsy (Autoclavable cryoprobe 20416-032 (ERBE, Germany) Flexible FB-55CD-1 Olympus forceps
4 Recruiting Investigation Into the Automated Drainage of Recurrent Effusions From the Pleural Space in Thoracic Malignancy.
Condition: Pleural Effusion
Intervention: Device: The pleurapump system
5 Not yet recruiting Immunomagnetic Detection of Cancer Cells in Pleural Effusion in Lung Cancer Patients as Additional Staging and Prognostic Tool
Condition: Lung Cancer
Intervention: Device: Immunomagnetic Detection
6 Unknown  Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax
Condition: Traumatic Pneumothorax
Interventions: Device: Pigtail catheter insertion (Cook);   Device: chest tube (28-French)
7 Not yet recruiting Comparison of Intrapleural Urokinase and Video-Assisted Thorascopic Surgery in the Treatment of Parapneumonic Pleural Effusion in Children
Condition: Empyema, Pleural
Interventions: Drug: insertion of a chest drain with urokinase instillation;   Procedure: primary video-assisted thorascopic surgery
8 Unknown  Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax
Condition: Pneumothorax
Interventions: Procedure: Simple aspiration with minocycline pleurodesis;   Procedure: simple aspiration
9 Recruiting Pathophysiological Effects of Intrapleural Pressure Changes During Therapeutic Thoracentesis
Conditions: Pleural Effusion;   Exudative Pleuritis
Interventions: Procedure: Therapeutic thoracentesis;   Device: Pleural catheter;   Device: Pleural manometer
10 Recruiting Genetic Sequencing-Informed Targeted Therapy in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer
Conditions: Malignant Pericardial Effusion;   Malignant Pleural Effusion;   Recurrent Non-small Cell Lung Cancer;   Stage IIIB Non-small Cell Lung Cancer;   Stage IV Non-small Cell Lung Cancer
Interventions: Other: cytology specimen collection procedure;   Procedure: therapeutic procedure;   Drug: targeted therapy;   Other: laboratory biomarker analysis
11 Unknown  A Prospective, Randomized Controlled Trial for a Rapid Pleurodesis Protocol for the Management of Pleural Effusions
Condition: Malignant Pleural Effusions
Interventions: Other: Thoracoscopy and Pleurx;   Procedure: Thoracoscopy
12 Unknown  Angiogenic Cytokines and Fibrinolytic Activity in Parapneumonic Effusions
Condition: Pleural Effusion
Intervention: Device: pleural pigtail drainage
13 Unknown  Epidemiology and Outcome of Solitary Fibrous Tumors of the Pleura.
Condition: Solitary Fibrous Tumors of the Pleura
Intervention:
14 Recruiting Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy
Conditions: Pleural Effusion;   Pleurisy;   Empyema
Interventions: Drug: Cefazolin;   Other: saline
15 Recruiting The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection
Conditions: Pleural Effusion;   Pleural Effusion Malignant
Interventions: Drug: Naproxen;   Drug: Placebo
16 Unknown  Gene Expression Profiling of Breast Cancer Cells Predict the Response of Malignant Pleural Effusion
Conditions: Breast Neoplasms;   Neoplasm Metastasis;   Gene Expression Profiling;   Immunotherapy
Intervention: Biological: cytokine
17 Not yet recruiting Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions
Condition: Loculated or Non-draining Malignant Pleural Effusions
Intervention: Drug: Combination TISSUE PLASMINOGEN ACTIVATOR (TPA) AND DORNASE ALFA (DNASE)
18 Recruiting Management of Occult Pneumothoraces in Mechanically Ventilated Patients
Condition: Pneumothorax
Interventions: Procedure: chest drainage;   Other: close clinical observation
19 Not yet recruiting Interventional Treatment of Refractory Pneumothorax by Bronchoscope
Condition: Pneumothorax
Interventions: Other: Autologous blood;   Device: Bronchial plug
20 Recruiting Cisplatin for Malignant Pleural Effusion in Patients With Non-small-cell Lung Cancer
Condition: Pleural Effusion, Malignant
Intervention: Drug: cisplatin

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Indicates status has not been verified in more than two years