92 studies found for:    Open Studies | "Pleural Diseases"
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21 Not yet recruiting Comparison of Intrapleural Urokinase and Video-Assisted Thorascopic Surgery in the Treatment of Parapneumonic Pleural Effusion in Children
Condition: Empyema, Pleural
Interventions: Drug: insertion of a chest drain with urokinase instillation;   Procedure: primary video-assisted thorascopic surgery
22 Not yet recruiting Necessity of Using Pleural Drainage Tubes After IMA Harvesting During Cardiac Surgery
Condition: Pleural Effusions Post Coronary Artery Bypass Graft
Intervention: Procedure: No Pleural Chest Tube
23 Recruiting Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions
Condition: Loculated or Non-draining Malignant Pleural Effusions
Intervention: Drug: Combination TISSUE PLASMINOGEN ACTIVATOR (TPA) AND DORNASE ALFA (DNASE)
24 Recruiting Genetic Sequencing-Informed Targeted Therapy in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer
Conditions: Malignant Pericardial Effusion;   Malignant Pleural Effusion;   Recurrent Non-small Cell Lung Cancer;   Stage IIIB Non-small Cell Lung Cancer;   Stage IV Non-small Cell Lung Cancer
Interventions: Other: cytology specimen collection procedure;   Procedure: therapeutic procedure;   Drug: targeted therapy;   Other: laboratory biomarker analysis
25 Recruiting Metformin Hydrochloride and Combination Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Conditions: Brenner Tumor;   Malignant Ascites;   Malignant Pleural Effusion;   Ovarian Clear Cell Cystadenocarcinoma;   Ovarian Endometrioid Adenocarcinoma;   Ovarian Mixed Epithelial Carcinoma;   Ovarian Serous Cystadenocarcinoma;   Ovarian Undifferentiated Adenocarcinoma;   Recurrent Fallopian Tube Cancer;   Recurrent Ovarian Epithelial Cancer;   Recurrent Ovarian Germ Cell Tumor;   Recurrent Primary Peritoneal Cavity Cancer;   Stage IIIA Fallopian Tube Cancer;   Stage IIIA Ovarian Epithelial Cancer;   Stage IIIA Ovarian Germ Cell Tumor;   Stage IIIA Primary Peritoneal Cavity Cancer;   Stage IIIB Fallopian Tube Cancer;   Stage IIIB Ovarian Epithelial Cancer;   Stage IIIB Ovarian Germ Cell Tumor;   Stage IIIB Primary Peritoneal Cavity Cancer;   Stage IIIC Fallopian Tube Cancer;   Stage IIIC Ovarian Epithelial Cancer;   Stage IIIC Ovarian Germ Cell Tumor;   Stage IIIC Primary Peritoneal Cavity Cancer;   Stage IV Fallopian Tube Cancer;   Stage IV Ovarian Epithelial Cancer;   Stage IV Ovarian Germ Cell Tumor;   Stage IV Primary Peritoneal Cavity Cancer
Interventions: Drug: paclitaxel;   Drug: carboplatin;   Drug: docetaxel;   Drug: metformin hydrochloride;   Drug: placebo;   Other: laboratory biomarker analysis
26 Recruiting Pigtail Catheter: a Less Invasive Option for Pleural Drainage of Recurrent Hepatic Hydrothorax
Condition: Pleural Effusion
Intervention: Device: Pigtail catheter
27 Recruiting Diagnostic Accuracy of Pleural Effusion Aspergillosis Biomarker Testing
Conditions: Invasive Aspergillosis;   Pleural Effusion;   Immunosuppression
Intervention:
28 Recruiting Biomarker Levels During Indwelling Pleural cAtheter Sample Testing
Condition: Malignant Pleural Effusions
Intervention:
29 Recruiting Mechanical Ventilation During Cardiac Surgery
Conditions: Respiratory Failure;   Pneumothorax;   Atelectasis;   Aspiration Pneumonia;   Bronchospasm
Interventions: Procedure: Non-ventilation during CPB;   Procedure: Ventilation with CPAP;   Procedure: Ventilation with 5 act/minute;   Device: CPAP;   Device: Ventilator: 5 act/minute
30 Recruiting Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy
Conditions: Lymphoma;   Malignant Mesothelioma;   Malignant Pericardial Effusion;   Malignant Pleural Effusion;   Non-small Cell Lung Cancer;   Small Cell Lung Cancer;   Soft Tissue Sarcoma;   Thymoma and Thymic Carcinoma
Interventions: Drug: doxepin hydrochloride;   Other: placebo;   Procedure: quality-of-life assessment;   Other: questionnaire administration;   Other: laboratory procedure
31 Recruiting Efficacy and Safety of Bevacizumab Versus Pulvis Talci in Malignant Pleural Effusion
Condition: Malignant Pleural Effusion
Interventions: Drug: Bevacizumab;   Drug: Pulvis talci
32 Recruiting Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer
Conditions: Non-small Cell Lung Cancer;   Malignant Pleural Effusion
Intervention: Drug: Bevacizumab
33 Recruiting Pleural and Pericardial Effusion Following Open Heart Surgery
Conditions: Heart Disease;   Pleural Effusion;   Pericardial Effusion
Intervention: Procedure: pleuracentesis
34 Recruiting Multicentre Study Comparing Indwelling Pleural Catheter With Talc Pleurodesis for Malignant Pleural Effusion Management
Condition: Pleural Effusion, Malignant
Interventions: Device: Indwelling Pleural Catheter;   Procedure: Talc Pleurodesis
35 Recruiting Tubeless Versus Standard Upper Pole Percutaneous Nephrolithotomy
Conditions: Pleural Effusion;   Pain
Interventions: Device: Double J stent  without nephrostomy;   Device: nephrostomy tube and double J stent
36 Recruiting VATS ( Video-Assisted Thoracoscopy) Compared to Reinsertion of a Thoracostomy Tube for Persistent Haemothorax
Conditions: Haemothorax;   Empyema
Interventions: Procedure: VATS ( Video-Assisted Thoracoscopy );   Procedure: Thoracostomy Tube reinsertion
37 Recruiting Intrapleural Administration of Bevacizumab Versus Endostar for Pleural Effusions in NSCLC
Condition: Non Small Cell Lung Cancer
Interventions: Drug: Bevacizumab;   Drug: recombinant human endostatin
38 Recruiting Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion
Conditions: Malignant Pleural Effusion;   Lung Cancer;   Mesothelioma;   Breast Cancer;   Ovarian Cancer
Intervention: Biological: AdV-tk + valacyclovir
39 Recruiting Randomized Study Comparing Pleural Drainage by Videothoracoscopy to Medical Drainage in Infectious Pleural Effusion
Condition: Infectious Pleural Effusion
Interventions: Device: Videothoracoscopy drainage;   Drug: Medical drainage
40 Not yet recruiting Using Ultrasound to Predict the Results of Draining Pleural Effusions
Condition: Pleural Effusion
Interventions: Other: Pleural Manometry;   Other: Thoracic ultrasonography;   Procedure: Pleural aspiration catheter OR chest drain (standard care);   Procedure: Talc slurry pleurodesis via chest drain (standard care)

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Indicates status has not been verified in more than two years