92 studies found for:    Open Studies | "Pleural Diseases"
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1 Not yet recruiting Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin
Conditions: Malignant Pleural Disease;   Mesothelioma;   Metastases;   Lung Cancer;   Breast Cancer
Interventions: Genetic: iCasp9M28z T cell infusions;   Drug: cyclophosphamide
2 Recruiting Impact of Respiratory Physiotherapy in the Management of Infectious Pleural Effusion
Conditions: Pleural Diseases;   Infection
Intervention: Other: Chest physiotherapy
3 Recruiting Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative Study
Conditions: Pleural Effusion;   Pleural Diseases
Intervention: Device: cryobiopsy (Autoclavable cryoprobe 20416-032 (ERBE, Germany) Flexible FB-55CD-1 Olympus forceps
4 Recruiting Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma
Condition: Malignant Pleural Mesothelioma
Intervention: Genetic: Adoptive Transfer of re-directed T cells
5 Recruiting Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma
Condition: Lung Cancer
Intervention: Biological: GL-ONC1
6 Recruiting A Feasibility and Safety Study of the Use of a Dedicated Ballooned Intercostal Drain
Condition: Pleural Effusion
Intervention: Device: Balloon-tipped intercostal drain
7 Unknown  Pathogenesis of Primary Spontaneous Pneumothorax
Condition: Pneumothorax
Intervention: Procedure: Thoracoscopic bullectomy
8 Recruiting Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer
Conditions: Non-small Cell Lung Cancer;   Malignant Pleural Effusion
Intervention: Drug: Bevacizumab
9 Recruiting Intrapleural Administration of Bevacizumab Versus Endostar for Pleural Effusions in NSCLC
Condition: Non Small Cell Lung Cancer
Interventions: Drug: Bevacizumab;   Drug: recombinant human endostatin
10 Recruiting Pathophysiological Effects of Intrapleural Pressure Changes During Therapeutic Thoracentesis
Conditions: Pleural Effusion;   Exudative Pleuritis
Interventions: Procedure: Therapeutic thoracentesis;   Device: Pleural catheter;   Device: Pleural manometer
11 Unknown  Evaluating the Diagnostic Validity of Inflammation-associated Markers for Tuberculous Pleurisy
Condition: To Investigate Diagnostic Aid of the Inflammation and Apoptosis-associated Markers and Apoptosis Pattern of PE Neutrophil for Tuberculous Pleurisy
Intervention:
12 Recruiting Randomized Study Comparing Pleural Drainage by Videothoracoscopy to Medical Drainage in Infectious Pleural Effusion
Condition: Infectious Pleural Effusion
Interventions: Device: Videothoracoscopy drainage;   Drug: Medical drainage
13 Recruiting NSAIDs Treatment in Children With Pleuropneumonia
Condition: Pleuro-pneumonia
Interventions: Drug: Ibuprofen;   Drug: Acetaminophen
14 Unknown  Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax
Condition: Pneumothorax
Interventions: Procedure: 1 apical pleurectomy;   Procedure: 2 pleural abrasion + minocycline pleurodesis
15 Recruiting VATS ( Video-Assisted Thoracoscopy) Compared to Reinsertion of a Thoracostomy Tube for Persistent Haemothorax
Conditions: Haemothorax;   Empyema
Interventions: Procedure: VATS ( Video-Assisted Thoracoscopy );   Procedure: Thoracostomy Tube reinsertion
16 Unknown  Respiratory Endoscopy: Diagnostic Yield, Technical Factors and Complications
Conditions: Lung Neoplasm;   Lung Diseases, Interstitial;   Respiratory Tract Infections;   Pleural Effusions
Intervention: Procedure: Respiratory endoscopy
17 Recruiting Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial)
Condition: Pleural Empyema
Interventions: Drug: tPA;   Drug: DNase;   Other: Placebo
18 Not yet recruiting Using Ultrasound to Predict the Results of Draining Pleural Effusions
Condition: Pleural Effusion
Interventions: Other: Pleural Manometry;   Other: Thoracic ultrasonography;   Procedure: Pleural aspiration catheter OR chest drain (standard care);   Procedure: Talc slurry pleurodesis via chest drain (standard care)
19 Recruiting Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced
Conditions: Urethritis;   Cervicitis;   Genital Mycoplasma Infection;   Chlamydia Trachomatis
Interventions: Drug: Azithromycin;   Drug: Doxycycline;   Drug: lymecycline
20 Recruiting Metformin Hydrochloride and Combination Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Conditions: Brenner Tumor;   Malignant Ascites;   Malignant Pleural Effusion;   Ovarian Clear Cell Cystadenocarcinoma;   Ovarian Endometrioid Adenocarcinoma;   Ovarian Mixed Epithelial Carcinoma;   Ovarian Serous Cystadenocarcinoma;   Ovarian Undifferentiated Adenocarcinoma;   Recurrent Fallopian Tube Cancer;   Recurrent Ovarian Epithelial Cancer;   Recurrent Ovarian Germ Cell Tumor;   Recurrent Primary Peritoneal Cavity Cancer;   Stage IIIA Fallopian Tube Cancer;   Stage IIIA Ovarian Epithelial Cancer;   Stage IIIA Ovarian Germ Cell Tumor;   Stage IIIA Primary Peritoneal Cavity Cancer;   Stage IIIB Fallopian Tube Cancer;   Stage IIIB Ovarian Epithelial Cancer;   Stage IIIB Ovarian Germ Cell Tumor;   Stage IIIB Primary Peritoneal Cavity Cancer;   Stage IIIC Fallopian Tube Cancer;   Stage IIIC Ovarian Epithelial Cancer;   Stage IIIC Ovarian Germ Cell Tumor;   Stage IIIC Primary Peritoneal Cavity Cancer;   Stage IV Fallopian Tube Cancer;   Stage IV Ovarian Epithelial Cancer;   Stage IV Ovarian Germ Cell Tumor;   Stage IV Primary Peritoneal Cavity Cancer
Interventions: Drug: paclitaxel;   Drug: carboplatin;   Drug: docetaxel;   Drug: metformin hydrochloride;   Drug: placebo;   Other: laboratory biomarker analysis

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Indicates status has not been verified in more than two years