90 studies found for:    Open Studies | "Osteosarcoma"
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Rank Status Study
21 Recruiting Investigation of [6R] 5,10-methylenetetrahydrofolate as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX.
Condition: Osteosarcoma
Interventions: Drug: Leucovorin;   Drug: [6R] 5,10-methylenetetrahydrofolate
22 Recruiting Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Osteosarcoma
Condition: Refractory or Relapsed Osteosarcoma
Intervention: Drug: Everolimus
23 Not yet recruiting A Clinical Trial on Efficacy and Safety for Lobaplatin and Gemcitabine in Combination With Docetaxel in the Second-line Treatments on Advanced Osteosarcoma
Condition: Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma
Interventions: Drug: Docetaxel+lobaplatin;   Drug: Gemcitabine+lobaplatin
24 Recruiting Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI
Conditions: Bone Cancer;   Chondrosarcoma;   Ewing's Sarcoma;   Osteosarcoma;   Rhabdomyosarcoma
Interventions: Drug: Feraheme;   Procedure: MR Scan
25 Recruiting To Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors
Conditions: Neuroblastoma;;   Rhabdomyosarcoma;;   Ewing's Sarcoma;;   Ewing's Tumor;;   Sarcoma, Ewing's;;   Sarcomas, Epitheliod;;   Sarcoma, Soft Tissue;;   Sarcoma, Spindle Cell;;   Melanoma;;   Malignant Melanoma;;   Clinical Oncology;;   Oncology, Medical;;   Pediatrics, Osteosarcoma;;   Osteogenic Sarcoma;;   Osteosarcoma Tumor;;   Sarcoma, Osteogenic;;   Tumors;;   Cancer;;   Neoplasia;;   Neoplasm;;   Histiocytoma;;   Fibrosarcoma;;   Dermatofibrosarcoma
Intervention: Drug: nab-paclitaxel
26 Recruiting Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?
Conditions: Osteosarcoma;   Spindle Cell Sarcoma of Bone
Interventions: Drug: Glucarpidase;   Drug: Methotrexate;   Drug: Folinic Acid
27 Recruiting Prospective Clinical Trial Evaluating Metronomic Chemotherapy in Patients With High-grade, Operable, Non-metastatic Osteosarcoma of the Extremity
Condition: High Grade Osteosarcoma
Intervention: Drug: continuous oral cyclophosphamide and methotrexate
28 Recruiting A Blanket Protocol to Study Oral Regorafenib in Patients With Refractory Liposarcoma, Osteogenic Sarcoma, and Ewing/Ewing-like Sarcomas
Conditions: Liposarcoma;   Osteogenic Sarcoma;   Ewing/Ewing-like Sarcoma
Interventions: Drug: Regorafenib;   Drug: Placebo
29 Recruiting Chemotherapy Resistance in Osteogenic Sarcoma and Other Solid Tumors
Condition: Osteosarcoma
Intervention: Biological: Tissue Procurement
30 Recruiting A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas
Conditions: Ewing Sarcomas;   Chondrosarcomas;   Osteosarcomas
Interventions: Drug: Regorafenib;   Drug: Placebo
31 Recruiting Phase I Dose Escalation of Monthly Intravenous Ra-223 Dichloride in Osteosarcoma
Condition: Sarcoma
Intervention: Drug: Ra-223 Dichloride
32 Recruiting Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma
Condition: Sarcoma
Intervention: Other: biologic sample preservation procedure
33 Recruiting Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcoma
Conditions: Neuroblastoma;   Ewings Sarcoma;   Osteogenic Sarcoma;   Rhabdomyosarcoma;   Synovial Sarcoma
Intervention: Biological: Autologous dendritic cell vaccine with adjuvant
34 Recruiting A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
Conditions: Sarcoma;   Osteosarcoma;   Rhabdomyosarcoma;   Neuroblastoma;   Melanoma
Interventions: Biological: Anti-GD2-CAR engineered T cells;   Drug: AP1903;   Drug: Cyclophosphamide
35 Recruiting Aerosol IL-2 for Pulmonary Metastases
Conditions: Sarcoma;   Solid Tumors;   Pulmonary Metastases;   Lung Metastases;   Osteosarcomas;   Ewing Sarcoma
Interventions: Drug: Aerosol IL-2;   Procedure: Symptom Assessment
36 Recruiting CC-486 (Oral Azacitidine) Bioequivalence Study in Patients With Solid Tumor or Hematologic Malignancies
Conditions: Hematological Neoplasms;   Non-Hodgkin's Lymphoma;   Hodgkin's Lymphoma;   Lymphoma;   Multiple Myeloma;   Acute Myeloid Leukemia;   Leukemia;   Myelodysplastic Syndromes;   Neoplasms;   Melanoma;   Breast Cancer;   Metastatic Breast Cancer;   Non-Small Cell Lung Cancer;   Small Cell Lung Cancer;   Renal Cell Carcinoma;   Glioblastoma Multiforme;   Osteosarcoma;   Sarcoma;   Thyroid Cancer;   Genitourinary
Interventions: Drug: CC-486;   Drug: Vidaza
37 Recruiting Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors
Conditions: Retinoblastoma;   Clear Cell Sarcoma;   Renal Cell Carcinoma;   Rhabdoid Tumor;   Wilms Tumor;   Hepatoblastoma;   Neuroblastoma;   Germ Cell Tumors;   Ewings Sarcoma;   Non-rhabdomyosarcoma Soft Tissue Sarcoma;   Osteosarcoma;   Rhabdomyosarcoma
Interventions: Drug: Simvastatin;   Drug: Cyclophosphamide;   Drug: Topotecan;   Drug: Myeloid growth factor
38 Recruiting Pretreatment Anti-Therapeutic Antibodies (PATA) in Patients Treated With hu14.18K322A Antibody
Conditions: Ewing Family of Tumors;   Melanoma;   Neuroblastoma;   Osteosarcoma
Intervention:
39 Not yet recruiting NAC to Prevent Cisplatin-induced Hearing Loss
Conditions: Neuroectodermal Tumors, Primitive;   Liver Neoplasms;   Neoplasms, Germ Cell and Embryonal;   Osteosarcoma;   Other Childhood Cancers Using Cisplatin-based Regimens
Intervention: Drug: N-Acetylcysteine
40 Recruiting Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy
Conditions: Osteosarcoma;   Ewing's Sarcoma;   Rhabdomyosarcoma;   Synovial Sarcoma;   Malignant Peripheral Nerve Sheath Sarcoma;   Malignant Fibrous Histiocytoma of the Bone;   Chondrosarcoma of the Bone
Interventions: Other: Endurance;   Other: Strengthening;   Other: Stretching;   Other: Home exercise program

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Indicates status has not been verified in more than two years