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103 studies found for:    Open Studies | "Osteosarcoma"
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Rank Status Study
21 Recruiting Investigation of [6R] 5,10-methylenetetrahydrofolate as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX.
Condition: Osteosarcoma
Interventions: Drug: Leucovorin;   Drug: [6R] 5,10-methylenetetrahydrofolate
22 Recruiting Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma
Condition: Recurrent Osteosarcoma
Interventions: Drug: Glembatumumab Vedotin;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study
23 Recruiting Humanized Monoclonal Antibody 3F8 (Hu3F8) With Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in the Treatment of Recurrent Osteosarcoma
Condition: Recurrent Osteosarcoma
Interventions: Biological: humanized anti-GD2 antibody;   Drug: GM-CSF
24 Unknown  Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Osteosarcoma
Condition: Refractory or Relapsed Osteosarcoma
Intervention: Drug: Everolimus
25 Recruiting Chemotherapy Resistance in Osteogenic Sarcoma and Other Solid Tumors
Condition: Osteosarcoma
Intervention: Biological: Tissue Procurement
26 Recruiting A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas
Conditions: Ewing Sarcomas;   Chondrosarcomas;   Osteosarcomas;   Chondroma
Interventions: Drug: Regorafenib;   Drug: Placebo
27 Unknown  A Clinical Trial on Efficacy and Safety for Lobaplatin and Gemcitabine in Combination With Docetaxel in the Second-line Treatments on Advanced Osteosarcoma
Condition: Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma
Interventions: Drug: Docetaxel+lobaplatin;   Drug: Gemcitabine+lobaplatin
28 Recruiting To Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors
Conditions: Neuroblastoma;;   Rhabdomyosarcoma;;   Ewing's Sarcoma;;   Ewing's Tumor;;   Sarcoma, Ewing's;;   Sarcomas, Epitheliod;;   Sarcoma, Soft Tissue;;   Sarcoma, Spindle Cell;;   Melanoma;;   Malignant Melanoma;;   Clinical Oncology;;   Oncology, Medical;;   Pediatrics, Osteosarcoma;;   Osteogenic Sarcoma;;   Osteosarcoma Tumor;;   Sarcoma, Osteogenic;;   Tumors;;   Cancer;;   Neoplasia;;   Neoplasm;;   Histiocytoma;;   Fibrosarcoma;;   Dermatofibrosarcoma
Intervention: Drug: nab-paclitaxel
29 Recruiting Prospective Clinical Trial Evaluating Metronomic Chemotherapy in Patients With High-grade, Operable, Non-metastatic Osteosarcoma of the Extremity
Condition: High Grade Osteosarcoma
Intervention: Drug: continuous oral cyclophosphamide and methotrexate
30 Recruiting SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Refractory Liposarcoma, Osteogenic Sarcoma, and Ewing Sarcomas
Conditions: Liposarcoma;   Osteogenic Sarcoma;   Ewing/Ewing-like Sarcoma
Interventions: Drug: Regorafenib;   Drug: Placebo
31 Recruiting Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies
Conditions: Tumors;   Solid Malignant Tumors;   Osteosarcoma;   Differentiated Thyroid Cancer (DTC)
Interventions: Drug: Lenvatinib;   Drug: Ifosfamide;   Drug: Etoposide
32 Recruiting A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
Conditions: Sarcoma;   Osteosarcoma;   Neuroblastoma;   Melanoma
Interventions: Biological: Anti-GD2-CAR engineered T cells;   Drug: AP1903;   Drug: Cyclophosphamide
33 Recruiting Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors
Conditions: Ewing Sarcoma;   Neuroblastoma;   Rhabdomyosarcoma;   Osteosarcoma;   CNS Tumors
Interventions: Procedure: Allogeneic HCT;   Drug: Donor NK Cell Infusion
34 Recruiting Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies
Conditions: Hematological Neoplasms;   Non-Hodgkin's Lymphoma;   Hodgkin's Lymphoma;   Lymphoma;   Multiple Myeloma;   Acute Myeloid Leukemia;   Leukemia;   Myelodysplastic Syndromes;   Neoplasms;   Melanoma;   Breast Cancer;   Metastatic Breast Cancer;   Non-Small Cell Lung Cancer;   Small Cell Lung Cancer;   Renal Cell Carcinoma;   Glioblastoma Multiforme;   Osteosarcoma;   Sarcoma;   Thyroid Cancer;   Genitourinary
Interventions: Drug: CC-486;   Drug: Vidaza
35 Recruiting Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma
Condition: Sarcoma
Intervention: Other: biologic sample preservation procedure
36 Recruiting Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma
Conditions: Osteosarcoma;   Ewing Sarcoma;   Rhabdomyosarcoma;   Soft Tissue Sarcoma
Interventions: Drug: nab-Paclitaxel;   Drug: Gemcitabine
37 Not yet recruiting Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer
Conditions: Cancer;   Toxicity Due to Chemotherapy;   Sarcoma;   Osteosarcoma;   Lymphoma;   Ewing Sarcoma
Intervention: Drug: Triptorelin (GnRHa) + Chemotherapy
38 Recruiting Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors
Conditions: Glioma;   Rhabdomyosarcoma;   Osteosarcoma;   Medulloblastoma;   Neuroectodermal Tumor;   Ependymoma;   Ewing's Sarcoma;   Wilms Tumor
Interventions: Biological: Erlotinib;   Drug: Temozolomide
39 Not yet recruiting HIFU Hyperthermia With Liposomal Doxorubicin (DOXIL) for Relapsed or Refractory Pediatric and Young Adult Solid Tumors
Conditions: Rhabdomyosarcoma;   Neuroblastoma;   Sarcoma;   Sarcoma, Ewing;   Osteosarcoma
Interventions: Drug: Doxorubicin HCl liposomal injection;   Device: Philips Sonalleve MR-HIFU Hyperthermia
40 Recruiting TCRαβ+/CD19+ Depleted Haploidentical HSCT + Zoledronate
Conditions: Acute Myeloid Leukemia;   Acute Lymphoblastic Leukemia;   Hodgkin Lymphoma;   Non-Hodgkin Lymphoma;   Myelodysplastic Syndrome;   Myeloproliferative Syndrome;   Rhabdomyosarcoma;   Ewing Sarcoma;   Primitive Neuroectodermal Tumor;   Osteosarcoma;   Neuroblastoma
Interventions: Procedure: TCRαβ+/CD19+ depleted Haploidentical HSCT;   Drug: Zoledronate

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