60 studies found for:    Open Studies | "Oropharyngeal Neoplasms"
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1 Unknown  Cetuximab & Concomitant-Boost Accelerated RT in Patients With Locally Advanced Oropharynx Squamous Cell Carcinoma.
Condition: Oropharyngeal Neoplasms
Intervention: Drug: Cetuximab
2 Recruiting De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study
Conditions: Carcinoma, Squamous Cell;   Head and Neck Neoplasms;   Oropharyngeal Neoplasms
Interventions: Radiation: Intensity Modulated Radiotherapy (IMRT);   Drug: Cisplatin (or alternative);   Procedure: Assessment for surgical evaluation
3 Recruiting Post Operative Adjuvant Therapy De-intensification Trial for Human Papillomavirus-related, p16+ Oropharynx Cancer
Condition: Oropharyngeal Neoplasms
Interventions: Radiation: Intensity-modulated radiation therapy (IMRT);   Drug: Cisplatin
4 Recruiting A Post-Market Clinical Trial for Access and Visualization of the Oropharynx and Hypopharynx During Transoral Procedures
Conditions: OSA;   Oral Disease;   Oropharyngeal Neoplasms;   Hypopharyngeal Neoplasms
Intervention:
5 Not yet recruiting Paclitaxel, Cisplatin and BYL719 for HPV-Associated Oropharyngeal Squamous Cell Carcinoma
Conditions: Carcinoma, Squamous;   Squamous Cell Carcinoma;   Oropharyngeal Neoplasms;   Oropharyngeal Cancer
Interventions: Drug: cisplatin;   Drug: paclitaxel;   Drug: BYL719
6 Unknown  Analgesia of Fibula Free Flap Donor Site by Peri-Neuronal Catheter in Oro-Pharyngeal Carcinoma Surgery
Condition: Oropharyngeal Neoplasms
Intervention: Device: Peri-Neuronal Catheter
7 Recruiting Interest of Narrow Band Imaging in Detection of Upper Aerodigestive Cancers
Conditions: Squamous Cell Carcinoma of Oropharynx;   Squamous Cell Carcinoma of Hypopharynx;   Squamous Cell Carcinoma of Larynx
Intervention: Procedure: WL and NBI
8 Recruiting Effectiveness of Adjuvant Radiotherapy in Small Oropharyngeal Squamous Cell Cancer and Single Lymph Node Metastasis.
Conditions: Oropharyngeal Cancer;   Oral Cancer;   Lymph Node Metastasis
Intervention: Radiation: Radiation therapy
9 Recruiting Photon/Proton Radiation Therapy for Oropharyngeal Cancers
Condition: Oropharyngeal Cancers
Intervention:
10 Recruiting A Feasibility Study on Adaptive 18F-FDG-guided Radiotherapy for Recurrent and Second Primary Head and Neck Cancer in the Previously Irradiated Territory.
Conditions: Recurrent and Second Primary Squamous Cell Carcinoma of the Oral Cavity in the Previously Irradiated Territory in Case of Primary Unresectable Tumor.;   Recurrent and Second Primary Squamous Cell Carcinoma of the Oropharynx in the Previously Irradiated Territory in Case of Primary Unresectable Tumor.;   Recurrent and Second Primary Squamous Cell Carcinoma of the Hypopharynx in the Previously Irradiated Territory in Case of Primary Unresectable Tumor.;   Recurrent and Second Primary Squamous Cell Carcinoma of the Larynx in the Previously Irradiated Territory in Case of Primary Unresectable Tumor.
Intervention: Radiation: [18F]FDG-PET-voxel intensity-based IMRT
11 Recruiting Reduced-Dose Intensity-Modulated Radiation Therapy With or Without Cisplatin in Treating Patients With Advanced Oropharyngeal Cancer
Conditions: Stage III Oropharyngeal Squamous Cell Carcinoma;   Stage IVA Oropharyngeal Squamous Cell Carcinoma;   Stage IVB Oropharyngeal Squamous Cell Carcinoma;   Stage IVC Oropharyngeal Squamous Cell Carcinoma;   Tongue Carcinoma
Interventions: Radiation: Intensity-Modulated Radiation Therapy;   Drug: Cisplatin;   Other: Quality-of-Life Assessment;   Other: Laboratory Biomarker Analysis
12 Recruiting Phase I Study of IMRT and Molecular-Image Guided Adaptive Radiation Therapy for Advanced HNSCC
Conditions: Salivary Gland Squamous Cell Carcinoma;   Stage II Salivary Gland Cancer;   Stage II Squamous Cell Carcinoma of the Hypopharynx;   Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage II Squamous Cell Carcinoma of the Oropharynx;   Stage II Verrucous Carcinoma of the Oral Cavity;   Stage III Salivary Gland Cancer;   Stage III Squamous Cell Carcinoma of the Hypopharynx;   Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage III Squamous Cell Carcinoma of the Oropharynx;   Stage III Verrucous Carcinoma of the Oral Cavity;   Stage IV Salivary Gland Cancer;   Stage IV Squamous Cell Carcinoma of the Hypopharynx;   Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity;   Stage IV Squamous Cell Carcinoma of the Oropharynx;   Stage IV Verrucous Carcinoma of the Oral Cavity
Interventions: Radiation: intensity-modulated radiation therapy;   Drug: cisplatin;   Radiation: image-guided adaptive radiation therapy;   Other: 3'-deoxy-3'-[18F]fluorothymidine;   Procedure: positron emission tomography/computed tomography;   Radiation: fludeoxyglucose F 18
13 Recruiting A Phase II Study In Patients With Advanced Head And Neck Cancer Of Standard Chemoradiation And Add-On Cetuximab
Conditions: Oropharyngeal Cancer;   Hypopharyngeal Cancer;   Laryngeal Cancer
Intervention: Drug: Cetuximab
14 Recruiting A Phase II Randomized Trial for Early-stage Squamous Cell Carcinoma of the Oropharynx: Radiotherapy vs Trans-oral Robotic Surgery (ORATOR)
Condition: Early-Stage Squamous Cell Carcinoma of the Oropharynx
Interventions: Radiation: Radiotherapy;   Procedure: Transoral Robotic Surgery + Neck Dissection
15 Recruiting HPV Serum DNA Levels Predicting Outcome in p16+ Squamous Cell Head and Neck Cancer
Condition: Subjects With p16+/HPV+ Squamous Cell Carcinomas of the Oropharynx.
Intervention: Other: Obtaining Human tissue
16 Recruiting Induction Chemotherapy With TP+5-FU or TP+Cetuximab Followed by Radioimmuptherapy for Locally Advanced or Not Resectable SCCHNN
Conditions: Squamous Cell Carcinoma of the Hypopharynx Stage III;   Squamous Cell Carcinoma of the Hypopharynx Stage IV;   Squamous Cell Carcinoma of the Larynx Stage III;   Squamous Cell Carcinoma of the Larynx Stage IV;   Squamous Cell Carcinoma of the Oropharynx Stage III;   Squamous Cell Carcinoma of the Oropharynx Stage IV;   Squamous Cell Carcinoma of the Oral Cavity Stage III;   Squamous Cell Carcinoma of the Oral Cavity Stage IV
Interventions: Drug: Docetaxel;   Drug: Cisplatin;   Drug: 5-fluorouracil;   Biological: Cetuximab Induction;   Biological: Cetuximab Radioimmunotherapy;   Radiation: Boost irradiation
17 Recruiting Reduced-intensity Therapy for Oropharyngeal Cancer in Non-smoking HPV-16 Positive Patients
Conditions: Squamous Cell Carcinoma of the Oropharynx;   HPV
Intervention: Radiation: Cetuximab
18 Recruiting Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer
Conditions: Human Papilloma Virus Infection;   Stage III Squamous Cell Carcinoma of the Oropharynx;   Stage IVA Squamous Cell Carcinoma of the Oropharynx;   Stage IVB Squamous Cell Carcinoma of the Oropharynx
Interventions: Drug: paclitaxel albumin-stabilized nanoparticle formulation;   Drug: carboplatin;   Radiation: radiation therapy;   Drug: paclitaxel;   Drug: fluorouracil;   Drug: hydroxyurea;   Drug: cisplatin;   Other: laboratory biomarker analysis;   Procedure: quality-of-life assessment
19 Not yet recruiting Post-operative Adjuvant Treatment for HPV-positive Tumours (PATHOS)
Condition: Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer
Interventions: Drug: Cisplatin;   Radiation: Postoperative radiotherapy
20 Recruiting T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated Cancers
Conditions: Vaginal Cancer;   Cervical Cancer;   Anal Cancer;   Penile Cancer;   Oropharyngeal Cancer
Interventions: Drug: Fludarabine;   Drug: Cyclophosphamide;   Biological: E6 TCR;   Drug: Aldesleukin

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