Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
41 studies found for:    Open Studies | "Neurofibromatoses"
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Rank Status Study
21 Recruiting MEK Inhibitor PD-0325901 Trial in Adolescents and Adults With NF1
Condition: Neurofibromatosis Type 1 and Growing or Symptomatic, Inoperable PN
Intervention: Drug: PD-0325901
22 Unknown  Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas
Conditions: Neurofibromatosis Type 1;   Precancerous Condition
Interventions: Drug: methotrexate;   Drug: vinblastine sulfate
23 Recruiting Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma
Conditions: Neurofibromatosis Type 2;   Neuroma, Acoustic
Intervention: Drug: RAD001, everolimus
24 Recruiting Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas
Conditions: Neurofibromatosis Type 2;   Progressive Vestibular Schwannomas
Intervention: Drug: Bevacizumab
25 Unknown  Medical Treatment of "High-Risk" Neurofibromas
Condition: Neurofibromatosis 1
Interventions: Drug: Peg-Interferon alpha-2b;   Drug: Celecoxib (Celebrex);   Drug: Temozolomide (temodar);   Drug: Vincristine Sulfate (Oncovin)
26 Recruiting Photodynamic Therapy (PDT) for Benign Dermal Neurofibromas (NF1)
Condition: Neurofibromatoses
Interventions: Drug: Levulan (5-aminolevulinic acid) uptake.;   Drug: Levulan (5-aminolevulinic acid) photodynamic therapy.
27 Recruiting Concentration and Activity of Lapatinib in Vestibular Schwannomas
Conditions: Vestibular Schwannoma;   NF2;   Neurofibromatosis 2;   Acoustic Neuroma;   Auditory Tumor
Intervention: Drug: lapatinib
28 Recruiting Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Conditions: Childhood Cerebellar Astrocytoma;   Childhood Cerebral Astrocytoma;   Childhood Mixed Glioma;   Childhood Pilocytic Astrocytoma;   Neurofibromatosis Type 1;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Oligodendroglioma;   Recurrent Childhood Pilocytic Astrocytoma;   Recurrent Childhood Visual Pathway Glioma
Interventions: Drug: Selumetinib;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study
29 Recruiting Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas
Conditions: Neurofibromatosis Type 2;   Vestibular Schwannomas;   Meningiomas
Intervention: Drug: RAD001 10mg p.o. daily
30 Recruiting Effect of Implant Position on Magnetic Resonance Image Distortion
Condition: Neurofibromatosis Type 2
Intervention: Device: MR imaging
31 Not yet recruiting Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma
Conditions: Vestibular Schwannoma;   Meningioma;   Acoustic Neuroma;   Neurofibromatosis Type 2
Intervention: Drug: AR-42
32 Recruiting Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas
Condition: Plexiform Neurofibromas
Intervention: Drug: Imatinib Mesylate
33 Recruiting Study to Investigate the Efficacy and Safety of GL2702 GLARS-NF1tablet and Harnal-D - Tablet in BPH Patients With LUTS
Condition: Benign Prostatic Hyperplasia
Interventions: Drug: Tamsulosin HCL 0.4mg;   Drug: Tamsulosin HCL 0.2mg
34 Recruiting Auditory Brainstem Implantation in Young Children
Conditions: Developmental Cochlear Nerve Deficiency;   Acquired Cochlear Nerve Deficiency;   Cochlear Aplasia;   Post-meningitis Cochlear Ossification;   Cochlear Malformation
Intervention: Device: Auditory Brainstem Implantation in Children
35 Recruiting Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors
Conditions: Malignant Peripheral Nerve Sheath Tumors;   MPNST;   Sarcoma
Interventions: Drug: everolimus;   Drug: bevacizumab
36 Recruiting The Use of a Distress Thermometer in a Pediatric Research Setting: An Exploratory Pilot Study
Conditions: Cancer;   HIV Infections
Intervention:
37 Recruiting Diagnosis of Pheochromocytoma
Condition: Pheochromocytoma
Intervention:
38 Unknown  First Clinical Study of Erbium - Yttrium Aluminium Garnet (YAG) Laser Vaporization of Cutaneous Neurofibromas
Condition: Cutaneous Neurofibromas
Intervention: Procedure: Erbium-YAG laser vaporization
39 Not yet recruiting Study of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery
Condition: Neuroendocrine Tumors
Interventions: Drug: Sunitinib;   Drug: Everolimus;   Procedure: Surgery
40 Recruiting Proton Radiation Therapy for Spinal Tumors
Conditions: Nerve Sheath Tumors;   Neurofibroma
Interventions: Radiation: Proton Radiation for MPNST;   Radiation: Proton Radiation  for neurofibromas

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Indicates status has not been verified in more than two years