Now Available: Final Rule for FDAAA 801 and NIH Policy on Clinical Trial Reporting
52 studies found for:    Open Studies | "Neurofibromatoses"
Show Display Options
Rank Status Study
21 Not yet recruiting AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas
Conditions: Neurofibromatosis 2;   Meningioma
Intervention: Drug: AZD2014
22 Recruiting Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma
Conditions: Neurofibromatosis Type 2;   Neuroma, Acoustic
Intervention: Drug: RAD001, everolimus
23 Recruiting Effect of Lamotrigine on Cognition in NF1
Condition: Neurofibromatosis Type 1
Interventions: Drug: Lamotrigine;   Drug: Placebo
24 Recruiting Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas
Conditions: Neurofibromatosis Type 2;   Progressive Vestibular Schwannomas
Intervention: Drug: Bevacizumab
25 Recruiting The Cognitive Variability in NF1 and TSC Monozygotic Twins
Conditions: Neurofibromatosis Type I;   Tuberous Sclerosis Complex
Intervention:
26 Recruiting Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas
Condition: Plexiform Neurofibromas
Intervention: Drug: Imatinib Mesylate
27 Recruiting PLX3397 in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN)
Conditions: Neurofibroma, Plexiform;   Precursor Cell Lymphoblastic Leukemia-Lymphoma;   Leukemia, Prolymphocytic, Acute;   Sarcoma
Intervention: Drug: PLX3397
28 Unknown  First Clinical Study of Erbium - Yttrium Aluminium Garnet (YAG) Laser Vaporization of Cutaneous Neurofibromas
Condition: Cutaneous Neurofibromas
Intervention: Procedure: Erbium-YAG laser vaporization
29 Not yet recruiting Resiliency Training for Patients With NF2 Via Videoconferencing With Skype
Condition: Neurofibromatosis 2
Interventions: Behavioral: Stress Management Group 1;   Behavioral: Stress Management Group 2
30 Available Compassionate Use Arm - ABI541 ABI for 10 NF2 Patients
Conditions: Neurofibromatosis Type 2;   Severe Profound Sensorineural Hearing Loss
Intervention: Device: Nucleus Profile ABI541 Auditory Brainstem Implant
31 Recruiting Feasibility and Clinically Application of Magnetic Resonance Fingerprinting
Conditions: Neurofibromatosis Type 1;   Brain Tumor;   Glioma
Interventions: Device: Magnetic Resonance Imaging;   Device: Magnetic Resonance Fingerprinting
32 Unknown  Concentration and Activity of Lapatinib in Vestibular Schwannomas
Conditions: Vestibular Schwannoma;   NF2;   Neurofibromatosis 2;   Acoustic Neuroma;   Auditory Tumor
Intervention: Drug: lapatinib
33 Recruiting Vaccine Therapy in Treating Patients With Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery
Conditions: Metastatic Malignant Peripheral Nerve Sheath Tumor;   Neurofibromatosis Type 1;   Recurrent Malignant Peripheral Nerve Sheath Tumor
Interventions: Procedure: Computed Tomography;   Other: Laboratory Biomarker Analysis;   Biological: Oncolytic Measles Virus Encoding Thyroidal Sodium Iodide Symporter;   Other: Quality-of-Life Assessment;   Procedure: Single Photon Emission Computed Tomography
34 Not yet recruiting Subtle Myocardial Deformation Abnormalities in Asymptomatic Nf-1 Patients
Condition: Neurofibromatosis Type 1
Intervention:
35 Recruiting Pomalidomide in Treating Younger Patients With Recurrent, Progressive or Refractory Central Nervous System Tumors
Conditions: Neurofibromatosis Type 1;   Recurrent Central Nervous System Neoplasm;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Visual Pathway Glioma;   Refractory Central Nervous System Neoplasm
Interventions: Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: Pomalidomide
36 Recruiting Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma
Conditions: Vestibular Schwannoma;   Meningioma;   Acoustic Neuroma;   Neurofibromatosis Type 2
Intervention: Drug: AR-42
37 Unknown  Effect of Implant Position on Magnetic Resonance Image Distortion
Condition: Neurofibromatosis Type 2
Intervention: Device: MR imaging
38 Recruiting Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas
Conditions: Neurofibromatosis Type 2;   Vestibular Schwannomas;   Meningiomas
Intervention: Drug: RAD001
39 Not yet recruiting A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 (NF1)
Conditions: NF1;   Congenital Pseudarthrosis of Tibia
Interventions: Device: INFUSE Bone Graft (BMP-2);   Procedure: Control Group
40 Recruiting Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations
Condition: Cancer
Interventions: Drug: Trametinib;   Drug: Dabrafenib

First Page    Show previous page of results Previous Page (1-20) Studies Shown (21-40) Next Page (41-52) Show next page of results    Last Page
Indicates status has not been verified in more than two years