1278 studies found for:    Open Studies | "Neuroectodermal Tumors"
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Rank Status Study
1 Recruiting Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor
Conditions: Medulloblastoma;   Neuroectodermal Tumor
Interventions: Biological: TTRNA-xALT;   Biological: TTRNA-DCs
2 Recruiting Phase I Trial of Afatinib in Pediatric Tumours
Conditions: Neuroectodermal Tumors;   Rhabdomyosarcoma
Intervention: Drug: afatinib
3 Recruiting Collecting and Storing Biological Samples From Patients With Ewing Sarcoma
Conditions: Askin Tumor;   Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Intervention: Other: laboratory biomarker analysis
4 Recruiting Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma
Conditions: Metastatic Ewing Sarcoma;   Metastatic Malignant Neoplasm in the Bone;   Metastatic Malignant Neoplasm in the Bone Marrow;   Metastatic Malignant Neoplasm in the Lung;   Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone;   Peripheral Primitive Neuroectodermal Tumor of Soft Tissues
Interventions: Drug: Cyclophosphamide;   Drug: Doxorubicin Hydrochloride;   Drug: Etoposide;   Radiation: External Beam Radiation Therapy;   Biological: Ganitumab;   Drug: Ifosfamide;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Radiation: Stereotactic Radiosurgery;   Procedure: Therapeutic Surgical Procedure;   Drug: Vincristine Sulfate
5 Recruiting Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors
Conditions: Adult Central Nervous System Germ Cell Tumor;   Adult Ependymoblastoma;   Adult Medulloblastoma;   Adult Pineoblastoma;   Adult Supratentorial Primitive Neuroectodermal Tumor;   Childhood Atypical Teratoid/Rhabdoid Tumor;   Childhood Central Nervous System Germ Cell Tumor;   Childhood Ependymoblastoma;   Medulloepithelioma;   Ototoxicity;   Recurrent Adult Brain Neoplasm;   Recurrent Childhood Central Nervous System Embryonal Neoplasm;   Recurrent Childhood Malignant Germ Cell Tumor;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Pineoblastoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions: Drug: Carboplatin;   Drug: Mannitol;   Drug: Melphalan;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Drug: Sodium Thiosulfate
6 Recruiting Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)
Conditions: Lymphoma;   Childhood Lymphoma;   Solid Tumor;   Childhood Solid Tumor;   Neuroblastoma;   Ewing Sarcoma;   Hodgkin Lymphoma;   Non-Hodgkin Lymphoma;   Rhabdomyosarcoma;   Soft Tissue Sarcoma;   Medulloblastoma;   Germ Cell Tumor;   Wilms Tumor;   Brain Neoplasms;   Medulloblastoma, Childhood;   Neuroectodermal Tumors, Primitive
Interventions: Drug: Genistein;   Drug: Placebo
7 Recruiting TCRαβ+/CD19+ Depleted Haploidentical HSCT + Zoledronate
Conditions: Acute Myeloid Leukemia;   Acute Lymphoblastic Leukemia;   Hodgkin Lymphoma;   Non-Hodgkin Lymphoma;   Myelodysplastic Syndrome;   Myeloproliferative Syndrome;   Rhabdomyosarcoma;   Ewing Sarcoma;   Primitive Neuroectodermal Tumor;   Osteosarcoma;   Neuroblastoma
Interventions: Procedure: TCRαβ+/CD19+ depleted Haploidentical HSCT;   Drug: Zoledronate
8 Recruiting Molecular-Guided Therapy for Childhood Cancer
Conditions: Neuroblastoma;   Medulloblastoma;   Glioma;   Ependymoma;   Choroid Plexus Neoplasms;   Craniopharyngioma;   Dysembryoplastic Neuroepithelial Tumor;   Meningioma;   Primitive Neuroectodermal Tumors (PNETs);   Germ Cell Tumors;   Rhabdomyosarcoma;   Non-rhabdomyosarcoma;   Ewings Sarcoma;   Osteosarcoma;   Wilms Tumor;   Renal Cell Carcinoma;   Malignant Rhabdoid Tumor;   Clear Cell Sarcoma;   Liver Tumors
Intervention: Device: Guided Therapy
9 Recruiting Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer
Conditions: Childhood Choroid Plexus Tumor;   Childhood Medulloblastoma;   Childhood Pineoblastoma;   Childhood Soft Tissue Sarcoma;   Childhood Supratentorial Primitive Neuroectodermal Tumor;   Neuroblastoma;   Osteosarcoma;   Retinoblastoma;   Wilms Tumor and Other Childhood Kidney Tumors;   Recurrent/Refractory Childhood Hodgkin Lymphoma;   Unspecified Childhood Solid Tumor, Protocol Specific
Intervention: Biological: filgrastim
10 Recruiting WEE1 Inhibitor MK-1775 and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
Conditions: Childhood Solid Neoplasm;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Neuroblastoma
Interventions: Drug: Irinotecan Hydrochloride;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: WEE1 Inhibitor AZD1775
11 Recruiting Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors
Conditions: Glioma;   Rhabdomyosarcoma;   Osteosarcoma;   Medulloblastoma;   Neuroectodermal Tumor;   Ependymoma;   Ewing's Sarcoma;   Wilms Tumor
Interventions: Biological: Erlotinib;   Drug: Temozolomide
12 Recruiting Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects
Conditions: Brain Cancer;   Brain Neoplasm;   Glioma;   Glioblastoma;   Gliosarcoma;   Malignant Brain Tumor;   Neoplasm, Neuroepithelial;   Neuroectodermal Tumors;   Neoplasm by Histologic Type;   Neoplasm, Nerve Tissue;   Nervous System Diseases
Interventions: Biological: DNX-2401;   Biological: pembrolizumab
13 Unknown  Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients
Conditions: Glioblastoma;   Nervous System Neoplasms;   Central Nervous System Neoplasms;   Astrocytoma;   Glioma;   Neoplasms, Neuroepithelial;   Neuroectodermal Tumors;   Neoplasms by Histologic Type;   Neoplasms, Nerve Tissue
Intervention:
14 Unknown  Establishment of a Brain and Spinal Tumor Tissue Bank
Conditions: Glioblastoma Multiforme;   Glioma;   Neuroectodermal Tumors
Intervention:
15 Recruiting NAC to Prevent Cisplatin-induced Hearing Loss
Conditions: Neuroectodermal Tumors, Primitive;   Liver Neoplasms;   Neoplasms, Germ Cell and Embryonal;   Osteosarcoma;   Other Childhood Cancers Using Cisplatin-based Regimens
Intervention: Drug: N-Acetylcysteine
16 Recruiting Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumors
Conditions: Glioma;   Neuroectodermal Tumors, Primitive;   Wilms Tumor;   Rhabdomyosarcoma;   Sarcoma, Ewing;   Osteosarcoma;   Retinoblastoma
Interventions: Drug: Metronomic Cyclophosphamide;   Drug: Thalidomide
17 Unknown  High Risk Primitive Neuroectodermal (PNET) Brain Tumors in Childhood
Conditions: Medulloblastoma;   Brain Tumors;   Neuroectodermal Tumors, Primitive
Intervention: Drug: Etoposide, carboplatin, melphalan, cisplatin, thiotepa
18 Recruiting Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Recurrent or Refractory Brain Tumors
Conditions: Childhood Astrocytoma;   Childhood Atypical Teratoid/Rhabdoid Tumor;   Diffuse Intrinsic Pontine Glioma;   Glioma;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Neoplasm;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Medulloblastoma;   Recurrent Primitive Neuroectodermal Tumor;   Refractory Brain Neoplasm
Interventions: Other: Laboratory Biomarker Analysis;   Biological: Sargramostim;   Biological: Wild-type Reovirus
19 Recruiting Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas
Conditions: Childhood Solid Neoplasm;   Metastatic Melanoma;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Hodgkin Lymphoma;   Recurrent Melanoma;   Recurrent Neuroblastoma;   Recurrent Non-Hodgkin Lymphoma;   Recurrent Osteosarcoma;   Recurrent Rhabdomyosarcoma;   Refractory Hodgkin Lymphoma;   Refractory Non-Hodgkin Lymphoma;   Stage IIIA Skin Melanoma;   Stage IIIB Skin Melanoma;   Stage IIIC Skin Melanoma;   Stage IV Skin Melanoma
Interventions: Biological: Ipilimumab;   Other: Laboratory Biomarker Analysis;   Biological: Nivolumab;   Other: Pharmacological Study
20 Recruiting Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies
Conditions: Adult Solid Neoplasm;   Childhood Solid Neoplasm;   Recurrent Adult Acute Lymphoblastic Leukemia;   Recurrent Childhood Acute Lymphoblastic Leukemia;   Recurrent Childhood Central Nervous System Neoplasm;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Refractory Central Nervous System Neoplasm
Interventions: Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: Talazoparib;   Drug: Temozolomide

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