Now Available: Final Rule for FDAAA 801 and NIH Policy on Clinical Trial Reporting
113 studies found for:    Open Studies | "Nervous System Malformations"
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Rank Status Study
21 Not yet recruiting Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia
Conditions: Arnold-Chiari Malformation, Type 1;   Chiari Malformation Type I;   Type I Arnold-Chiari Malformation;   Syringomyelia
Interventions: Procedure: Posterior fossa decompression;   Procedure: Dural Augmentation
22 Recruiting Extended Criteria For Fetal Myelomeningocele Repair
Conditions: Obesity;   Myelomeningocele;   Pregnancy
Intervention: Procedure: Open Fetal Repair of Myelomeningocele
23 Recruiting Genetic Heterogeneity and Genotype-phenotype Correlation of Children and Adults With Tuberous Sclerosis Complex
Conditions: Sclerosis Tuberosa;   Tuberous Sclerosis Complex;   Cerebral Sclerosis;   Nervous System Disorders
Intervention:
24 Not yet recruiting Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)
Conditions: Tuberous Sclerosis;   Angiofibroma;   Hypomelanotic Macule;   Plaque
Interventions: Drug: NPC-12G gel;   Drug: Placebo gel
25 Not yet recruiting Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis;   Angiofibroma;   Hypomelanotic Macule;   Plaque
Intervention: Drug: NPC-12G gel
26 Recruiting The Safety, Tolerability and Efficacy of Dronabinol, for the Treatment of Nausea and Vomiting in Familial Dysautonomia
Conditions: Nausea;   Vomiting;   Familial Dysautonomia
Interventions: Drug: Dronabinol;   Other: Placebo
27 Not yet recruiting Atorvastatin Therapy in Cerebral Cavernous Malformation: A Proof of Concept Phase I/II Trial
Condition: Cerebral Cavernous Malformation
Interventions: Drug: Atorvastatin;   Other: Placebo
28 Recruiting Treatment of Cerebral Arteriovenous Malformations With SQUID™ Liquid Embolic Agent
Condition: Cerebral Arteriovenous Malformations
Intervention: Device: SQUID™
29 Not yet recruiting Ulipristal Acetate In Disease Charcot-Marie-Tooth Type of 1A
Condition: CMT1A
Interventions: Drug: EllaOne;   Drug: EllaOne placebo
30 Not yet recruiting Tools for Therapeutic Evaluation in Charcot-Marie-Tooth Disease Type 1A: Outcome Measures and Biomarkers
Condition: Charcot-Marie-Tooth Disease Type 1A
Interventions: Other: Clinical evaluation;   Other: electrophysiological record;   Other: Muscle MRI;   Other: blood samples analysis
31 Recruiting Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
Conditions: Spinal Cord Injuries;   Cerebral Palsy;   Spinal Dysraphism;   Brain Injuries;   Spina Bifida;   Traumatic Brain Injury
Intervention: Device: MHealth
32 Recruiting Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT)
Condition: Charcot-Marie-Tooth Disease Type 1A
Interventions: Drug: PXT3003 dose 1;   Drug: PXT3003 dose 2;   Drug: placebo
33 Recruiting Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease
Condition: Charcot Marie Tooth Disease
Interventions: Other: Placebo;   Drug: Mexiletine
34 Recruiting Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency
Condition: Growth Hormone Deficiency With Pituitary Anomalies
Interventions: Drug: Macimorelin;   Drug: Insulin
35 Recruiting Carbidopa for the Treatment of Excessive Blood Pressure Variability
Conditions: Dysautonomia, Familial;   Baroreflex Failure Syndrome
Interventions: Drug: Carbidopa Low Dose;   Other: Placebo;   Drug: Carbidopa High Dose
36 Recruiting A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex.
Conditions: Tuberous Sclerosis Complex;   Seizures
Interventions: Drug: GWP42003-P;   Drug: Placebo
37 Recruiting Efficacy of Acetaminophen in Posterior Fossa Surgery
Conditions: Arnold-Chiari Malformation;   Posterior Fossa Tumors
Interventions: Drug: IV acetaminophen;   Drug: normal saline
38 Recruiting Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases
Conditions: Spinal Muscular Atrophy;   Charcot-Marie-Tooth Disease;   Muscular Dystrophy;   Spinal Muscular Atrophy With Respiratory Distress 1;   Amyotrophic Lateral Sclerosis;   Motor Neuron Disease;   Neuromuscular Disease;   Peroneal Muscular Atrophy;   Fragile X Syndrome
Intervention: Other: sample collection
39 Recruiting A Peer E-mentoring Intervention to Improve Employment
Conditions: Cerebral Palsy;   Spina Bifida;   Juvenile Arthritis;   Spinal Cord Injury;   Muscular Dystrophy;   Physical Disability
Intervention: Behavioral: Empowering youth towards employment
40 Recruiting Fetal and Maternal Head Circumference During Pregnancy in Israeli Population
Conditions: Maternal-Fetal Relations;   Microcephaly
Intervention: Other: no intervention

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Indicates status has not been verified in more than two years