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375 studies found for:    Open Studies | "Myelodysplastic Syndromes"
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21 Recruiting A Safety and Pharmacology Study of Atezolizumab Administered Alone or in Combination With Azacitidine in Participants With Myelodysplastic Syndromes
Condition: Myelodysplastic Syndromes
Interventions: Drug: Atezolizumab;   Drug: Azacitidine
22 Recruiting Efficacy of Eltrombopag Plus Lenalidomide Combination Therapy in Patients With IPSS Low and Intermediate-risk Myelodysplastic Syndrome With Isolated del5q
Condition: Myelodysplastic Syndromes
Interventions: Drug: Eltrombopag/Revolade;   Other: Placebo;   Drug: Lenalidomide
23 Recruiting A Phase II Pilot Study to Assess the Presence of Molecular Factors Predictive for Hematologic Response in Myelodysplastic Syndrome Patients Receiving Deferasirox Therapy.
Condition: Myelodysplastic Syndrome
Interventions: Procedure: Bone marrow aspirate;   Drug: Deferasirox
24 Recruiting The National Myelodysplastic Syndromes (MDS) Study
Condition: Myelodysplastic Syndromes (MDS)
Intervention: Other: Therapeutic
25 Not yet recruiting Study to Separately Evaluate the Activity of Talacotuzumab (JNJ-56022473) or Daratumumab in Transfusion-Dependent Participants With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) Who Are Relapsed or Refractory to Erythropoiesis-Stimulating Agent (ESA) Treatment
Condition: Myelodysplastic Syndromes
Interventions: Drug: Talacotuzumab;   Drug: Daratumumab
26 Not yet recruiting A Study Evaluating Venetoclax in Combination With Azacitidine Compared With Azacitidine Alone in Participants With Higher-Risk Myelodysplastic Syndromes (MDS) After Hypomethylating Agent-Failure
Condition: Myelodysplastic Syndromes (MDS)
Interventions: Drug: venetoclax;   Drug: azacitidine
27 Recruiting A Study of Luspatercept (ACE-536) to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes
Condition: Myelodysplastic Syndromes
Interventions: Drug: Luspatercept;   Other: Placebo
28 Recruiting A Clinical Trial Evaluating the Efficacy of Ultra Low Dose of Decitabine in Myelodysplastic Syndromes (MDS)
Condition: Myelodysplastic Syndromes (MDS)
Intervention: Drug: decitabine
29 Recruiting CPI-613 in Treating Patients With Myelodysplastic Syndromes Who Failed Previous Therapy
Condition: Previously Treated Myelodysplastic Syndromes
Intervention: Drug: 6,8-bis(benzylthio)octanoic acid
30 Recruiting A Prospective, Multicentre European Registry for Newly Diagnosed Patients With Myelodysplastic Syndromes
Condition: Myelodysplastic Syndromes (MDS)
Intervention: Other: No interventions
31 Not yet recruiting Entinostat and Pembrolizumab in Treating Patients With Myelodysplastic Syndrome After DNMTi Therapy Failure
Condition: Previously Treated Myelodysplastic Syndrome
Interventions: Drug: Entinostat;   Other: Laboratory Biomarker Analysis;   Biological: Pembrolizumab
32 Recruiting Combination Study of Deferasirox and Erythropoietin in Patients With Low- and Int-1-risk Myelodysplastic Syndrome.
Conditions: Adult Patients With Low Risk Myelodysplastic Syndrome;   Adult Patients With Int 1-risk Myelodysplastic Syndrome
Interventions: Drug: Erythropoietin alpha;   Drug: Deferasirox
33 Recruiting A Study Evaluating Venetoclax in Combination With Azacitidine Compared With Azacitidine Alone in Participants With Previously Untreated Higher-Risk Myelodysplastic Syndromes (MDS)
Condition: Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS)
Interventions: Drug: Venetoclax;   Drug: Azacitidine
34 Recruiting The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Due to International Prognostic Scoring System (IPSS) Low Risk Myelodysplastic Syndrome (MDS)
Condition: Myelodysplastic Syndrome
Interventions: Drug: Oral Azacitidine;   Drug: Placebo
35 Recruiting Quality of Life and Symptoms in Patients With Newly Diagnosed Myelodysplastic Syndromes
Conditions: Adult;   Myelodysplastic Syndromes
Interventions: Other: questionnaire administration;   Other: fatigue assessment and management;   Other: observation;   Other: quality-of-life assessment
36 Recruiting Nivolumab and Ipilimumab With 5-azacitidine in Patients With Myelodysplastic Syndromes (MDS)
Conditions: Leukemia;   Myelodysplastic Syndrome
Interventions: Drug: Nivolumab;   Drug: Ipilimumab;   Drug: 5-azacitidine
37 Recruiting Efficacy and Safety of Ultra Small Dose Decitabine for the Lower Risk MDS Patients With Transfusion Dependent
Condition: Myelodysplastic Syndromes
Intervention: Drug: decitabine
38 Recruiting A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS)
Conditions: Myelodysplastic Syndromes;   Thrombocytopenia
Intervention: Drug: Eltrombopag
39 Recruiting CIK-Cells in Relapsing Patients With Acute Leukemia or Myelodysplastic Syndromes After SCT.
Conditions: Myelodysplastic Syndromes;   Acute Leukemia
Intervention: Drug: CIK-Cells
40 Not yet recruiting CB-839 + Azacitidine for Treatment of Myelodysplastic Syndrome (MDS)
Conditions: Myelodysplastic Syndrome;   Other Diseases of Blood and Blood-forming Organs
Interventions: Drug: CB-839;   Drug: Azacitidine

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Study has passed its completion date and status has not been verified in more than two years.