Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
102 studies found for:    Open Studies | "Laryngeal Diseases"
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Rank Status Study
21 Unknown  Induction Docetaxel/Cisplatin/5-fluorouracil (TPF) as Selector for Chemo Radiation Therapy (RT) Versus Partial Laryngectomy in Advanced Laryngeal Cancer
Condition: Larynx Cancer
Interventions: Procedure: laryngoscopy;   Drug: Taxotere (Docetaxel), Cisplatin, 5FU
22 Unknown  Establishment of an Artificial Larynx After Total Laryngectomy
Condition: Carcinomatous Disease
Intervention: Device: PROTIP MEDICAL ( Artificial larynx prosthesis)
23 Recruiting Neck Dissection Via a Robot-assisted Transaxillary Approach in Patients With Squamous Cell Carcinoma of the Epi-larynx
Condition: Carcinoma, Squamous Cell
Intervention: Procedure: Neck Dissection
24 Recruiting Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck
Conditions: Carcinoma, Squamous Cell of Head and Neck;   HPV Positive Oropharyngeal Squamous Cell Carcinoma;   Hypopharyngeal Cancer;   Early Invasive Cervical Squamous Cell Carcinoma;   Carcinoma of Larynx;   Cancer of Nasopharynx
Interventions: Drug: BKM120;   Drug: Cisplatin;   Radiation: Intensity-modulated radiotherapy (IMRT)
25 Recruiting Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design
Condition: Squamous Cell Carcinoma of the Oropharynx, Larynx, or Hypopharynx
Interventions: Drug: Cisplatin;   Radiation: IMRT;   Drug: Docetaxel;   Drug: Cetuximab
26 Recruiting Visualization of the Larynx With the Airtraq Laryngoscope and Image Transmission
Condition: Anaesthesia
Intervention: Device: Airtraq visualization
27 Unknown  Intralesional Bevacizumab for Treating AIDS-associated Kaposi´s Sarcoma of the Larynx, Pharynx and Oral Cavity
Condition: Kaposi´s Sarcoma
Intervention: Drug: Bevacizumab
28 Unknown  TPF Plus Radiotherapy and Cetuximab to Avoid Total Laryngectomy in Patients With Larynx Cancer
Condition: Head and Neck Cancer
Interventions: Drug: TPF, radiotherapy and cetuximab;   Procedure: H&N surgery
29 Recruiting A Study of Chemo +/- Low-dose Radiation as Induction Therapy in SCCHN
Conditions: Head and Neck Cancer;   Larynx
Interventions: Radiation: Low dose fractionated radiation - 80cGy with chemotherapy;   Drug: Docetaxel  and Carboplatin AUC 6
30 Recruiting Nicotine Levels With Response Rates to Radiation Alone or With Chemo In Head & Neck Cancer
Conditions: Larynx Cancer;   Lip Cancer;   Oral Cavity Cancer;   Pharyngeal Cancer;   Oropharyngeal Cancer
Intervention:
31 Unknown  Erlotinib, Celecoxib and Reirradiation for Recurrent Head and Neck Cancer
Conditions: Cancer of the Pharynx;   Cancer of the Larynx;   Cancer of the Neck;   Paranasal Sinus Neoplasms;   Cancer of the Head
Intervention: Drug: erlotinib + celecoxib
32 Unknown  Speech and Swallowing Characteristics of Patients After Laryngectomy and the Effect on Quality of Life
Condition: Cancer of the Larynx
Intervention:
33 Recruiting Value of Narrow Band Imaging (NBI) Endoscopy in the Early Diagnosis of Laryngeal Cancer and Precancerous Lesions
Conditions: Chronic Inflammation of Hypopharynx;   Hoarseness;   Macroscopic Laryngeal Lesions;   Histological Confirmation of Dysplasia;   Carcinoma in Situ;   Invasive Carcinoma of Larynx;   Invasive Carcinoma of Hypo Pharynx;   Recurrent Respiratory Papillomatosis
Intervention: Device: NBI endoscopy
34 Unknown  Study of Blood and Tissue Samples From Patients With Larynx Cancer, Pharynx Cancer, or Oral Cavity Cancer
Condition: Head and Neck Cancer
Intervention: Other: laboratory biomarker analysis
35 Recruiting A Study Comparing Adaptive Biological Imaging - Voxel Intensity - Based Radiotherapy (Adaptive Dose Escalation) Versus Standard Radiotherapy for Head and Neck Cancer
Condition: Primary Non-operated Squamous Cell Carcinoma of the Oral Cavity, Oropharynx, Hypopharynx and Larynx.
Interventions: Radiation: Adaptive dose-painting-by-numbers;   Radiation: standard intensity-modulated radiotherapy (IMRT)
36 Recruiting A Feasibility Study on Adaptive 18F-FDG-guided Radiotherapy for Recurrent and Second Primary Head and Neck Cancer in the Previously Irradiated Territory.
Conditions: Recurrent and Second Primary Squamous Cell Carcinoma of the Oral Cavity in the Previously Irradiated Territory in Case of Primary Unresectable Tumor.;   Recurrent and Second Primary Squamous Cell Carcinoma of the Oropharynx in the Previously Irradiated Territory in Case of Primary Unresectable Tumor.;   Recurrent and Second Primary Squamous Cell Carcinoma of the Hypopharynx in the Previously Irradiated Territory in Case of Primary Unresectable Tumor.;   Recurrent and Second Primary Squamous Cell Carcinoma of the Larynx in the Previously Irradiated Territory in Case of Primary Unresectable Tumor.
Intervention: Radiation: [18F]FDG-PET-voxel intensity-based IMRT
37 Recruiting Observational Study of Swallowing Function After Treatment of Advanced Laryngeal Cancer
Conditions: Squamous Cell Carcinoma;   Laryngeal Cancer
Intervention:
38 Recruiting Evaluation of Laryngeal Ultrasonography Performance in Predicting Major Post Extubation Laryngeal Edema in Intensive Care Patients
Conditions: Laryngeal Edema;   Acute Respiratory Failure Requiring Reintubation
Intervention:
39 Recruiting Efficacy and Safety of Alginos Oral Suspension to Treat Laryngopharyngeal Reflux
Condition: Laryngopharyngeal Reflux
Interventions: Drug: Sodium alginate;   Drug: Placebo
40 Recruiting Effect of Intravenous Lidocaine and Dexamethasone Combination on Postoperative Sore Throat, Cough and Hoarseness.
Condition: Postoperative Sore Throat, Cough, Hoarseness
Interventions: Drug: LD: Lidocaine and dexamethasone;   Drug: L:Lidocaine;   Drug: D: Dexamethasone;   Drug: N: Normal saline (placebo)

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