87 studies found for:    Open Studies | "Lacrimal Apparatus Diseases"
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Rank Status Study
1 Not yet recruiting Innovative Imaging of the Conjunctiva, Cornea, and Ocular Adnexa : Study of a Handheld in Vivo Confocal Microscope and of a Fluorescent in Vivo Confocal Microscope
Conditions: Corneal Disease;   Blepharitis;   Lacrimal Apparatus Diseases;   Microscopy, Confocal
Interventions: Device: Handheld IVCM Vivascope 3000 (Caliber/Mavig) anesthesic eyedrop : oxybuprocaïne Thea 1,6 mg/0,4 ml;   Device: Multifluorescence IVCM vivascope 1500 ML (Caliber/Mavig);   Procedure: microangiography
2 Unknown  Pilot Study of a Homeopathic Therapy in Combination With Cyclosporin (Restasis) in the Treatment of Dry Eye Disease
Condition: Dry Eye Syndromes
Interventions: Drug: euphrasia based homeopathic therapy and cyclosporin;   Drug: cyclosporin solution
3 Recruiting Phase 2 Study With Cis-UCA Ophthalmic Solutions in Subjects With Dry Eye
Condition: Dry Eye Syndrome
Interventions: Drug: cis-UCA ophthalmic solution 1.0%;   Drug: cis-UCA ophthalmic solution 2.5%;   Drug: Placebo ophthalmic solution
4 Recruiting DNase Treatment for Dry Eyes
Condition: Dry Eye
Interventions: Drug: DNase;   Drug: Vehicle
5 Recruiting Effects of Conventional Dry Eye Treatments on the Ocular Surface Response to Low Humidity Environment in Patients With Keratoconjunctivitis Sicca
Conditions: Keratoconjunctivitis Sicca;   Dry Eye Syndrome
Intervention: Drug: dexamethasone, artificial tears
6 Not yet recruiting Estrogen and the Outer Eye in Women During Fertility Treatment
Condition: Dry Eye Syndromes
Intervention:
7 Not yet recruiting Safety, Tolerability and Systemic Pharmacokinetics of AGN-232411 in Healthy Participants and Participants With Dry Eye
Conditions: Healthy Volunteers;   Dry Eye Syndromes
Interventions: Drug: AGN-232411;   Drug: AGN-232411 Vehicle
8 Recruiting The Research Registry for Neonatal Lupus
Conditions: Neonatal Lupus;   Systemic Lupus Erythematosus;   Sjogren's Syndrome;   Congenital Heart Block
Intervention: Other: No intervention; observational
9 Unknown  Efficacy of FreshKote and Systane for the Treatment of Dry Eye and Improvement of Osmolarity
Condition: Dry Eye
Interventions: Drug: FreshKote;   Drug: Systane
10 Unknown  Comparison of Efficacy, Safety and Anti-Inflammatory Effect Between Topical 0.05%Cyclosporine A Emulsion and REFRESH® in Patients With Moderate to Severe Dry Eyes
Condition: Dry Eye
Intervention: Drug: 0.05% cyclosporin eye drop
11 Recruiting Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2)
Condition: Chronic Graft-versus-host Disease
Interventions: Drug: R348 Ophthalmic Solution, 0.2%;   Drug: R348 Ophthalmic Solution, 0.5%;   Other: Placebo Ophthalmic Solution
12 Not yet recruiting A Phase 2a, Randomized, Placebo Controlled, Study to Evaluate the Safety and Efficacy of AMG 557/MEDI5872 in Primary Sjögren's Syndrome
Condition: Primary Sjögren's Syndrome
Interventions: Biological: AMG 557/MEDI5872;   Biological: Placebo
13 Recruiting Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic Treatments
Conditions: Rheumatoid Arthritis;   Osteoarthritis;   Systemic Lupus Erythematosus;   Sjogren's Syndrome;   Scleroderma;   Spondylitis;   Gout;   Spinal Disease;   Chondrocalcinosis
Intervention:
14 Recruiting Agricultural Health Study Follow-up
Conditions: Rheumatoid Arthritis;   Lupus Erythematosus, Systemic;   Sjogren's Syndrome
Intervention:
15 Not yet recruiting Changes in Tear Osmolarity Over Time With Sustained Use of TheraTears
Condition: Dry Eye Syndrome
Intervention: Other: TheraTears lubricating drops
16 Not yet recruiting the Effect of HCG Treatment as a Cardiovascular Disease Morbidity Factor in Sjogren Syndrome Patients
Condition: Primary Sjogren Syndrome With Multisystem Involvement
Intervention: Other: Retrospective study
17 Not yet recruiting Three Dimension Tomography of Eye Structures by White Light Imaging Device
Conditions: Healthy Subjects;   Moderate to Severe Keratoconjunctivitis Sicca (KCS);   Dry Eye Syndrome (DES)
Intervention: Device: None invasive imaging of the tear film (AdOM)
18 Recruiting Effects of Sustained Reading on the Ocular Surface
Conditions: Dry Eye Syndromes;   Sjogren's Syndrome
Intervention:
19 Not yet recruiting Tear Osmolarity Clinical Utility in Dry Eye Disease
Condition: Dry Eye
Interventions: Other: Tear supplement;   Other: Tear supplement 2;   Dietary Supplement: Omega 3 nutrition supplement;   Device: Eye bag;   Other: Saline
20 Recruiting A Study to Evaluate Efficacy and Safety of Lifitegrast in Subjects With Dry Eye
Condition: Dry Eye Disease
Interventions: Drug: Lifitegrast;   Drug: Placebo

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Indicates status has not been verified in more than two years