Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
39 studies found for:    Open Studies | "Lacrimal Apparatus Diseases"
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Rank Status Study
1 Unknown  Pilot Study of a Homeopathic Therapy in Combination With Cyclosporin (Restasis) in the Treatment of Dry Eye Disease
Condition: Dry Eye Syndromes
Interventions: Drug: euphrasia based homeopathic therapy and cyclosporin;   Drug: cyclosporin solution
2 Not yet recruiting Pilot Study to Clinical Evaluate Device Prototypes in Dry Eye Patients
Condition: Dry Eye Syndrome
Intervention: Device: Lacrima medical Prototypes
3 Recruiting The Pathogenesis and Natural History of Sjogren s Syndrome
Conditions: Pathogenesis;   Sjogren's Syndrome;   Salivary Gland
Intervention:
4 Not yet recruiting A Phase 2a, Randomized, Placebo Controlled, Study to Evaluate the Safety and Efficacy of AMG 557/MEDI5872 in Primary Sjögren's Syndrome
Condition: Primary Sjögren's Syndrome
Interventions: Biological: AMG 557/MEDI5872;   Biological: Placebo
5 Unknown  Rebamipide for the Treatment of Xerostomia in sjögren Syndrome
Condition: Improving Symptoms of Dry Mouth in Sjőgren's Syndrome
Intervention: Drug: Rebamipide
6 Recruiting Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2)
Condition: Chronic Graft-versus-host Disease
Interventions: Drug: R348 Ophthalmic Solution, 0.2%;   Drug: R348 Ophthalmic Solution, 0.5%;   Other: Placebo Ophthalmic Solution
7 Not yet recruiting Aerobic Exercise in Primary Sjögren's Syndrome
Condition: Sjogren's Syndrome
Intervention: Other: aerobic exercise
8 Unknown  Treatment of Dry Eye With Supplements
Condition: Dry Eye Syndromes
Intervention: Dietary Supplement: Vitamac® Tag and Nacht capsules
9 Recruiting Efficacy and Safety of T2762 and Vismed® in Dry Eye Syndrome
Condition: Dry Eye Syndrome
Interventions: Device: T2762;   Device: Vismed®
10 Unknown  Allogeneic Mesenchymal Stem Cells Transplantation for Primary Sjögren's Syndrome (pSS)
Conditions: Sjogren's Syndrome;   Mesenchymal Stem Cells
Intervention: Biological: Allogeneic Mesenchymal Stem Cells (AlloMSC)
11 Recruiting Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis Sicca
Conditions: Keratoconjunctivitis Sicca;   Dry Eye Disease
Interventions: Drug: OTX-101 0.05%;   Drug: OTX-101 0.09%;   Drug: Vehicle
12 Unknown  A Placebo Controlled Double Masked Clinical Assessment Study of Essential Fatty Acid Supplement and Its Effect on Patients With Apparent Aqueous Deficient Dry Eye Syndrome
Condition: Dry Eye Syndrome
Intervention: Drug: Essential fatty acid supplement
13 Unknown  Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye
Conditions: Dry Eye;   Sjogren's Syndrome;   Graft vs. Host Disease
Intervention: Drug: Thymosin Beta 4 eye drops vs. vehicle
14 Unknown  Oral Nutrition Impact on Tear Film
Condition: Dry Eye Syndrome
Intervention: Dietary Supplement: Omega 3, Vitamins A, D3 and E
15 Recruiting Pilot Study to Evaluate SYL1001 Safety and Effect in Patients With Ocular Pain
Conditions: Ocular Pain;   Dry Eye Syndrome
Interventions: Drug: SYL1001;   Drug: Placebo
16 Recruiting Effects of Sustained Reading on the Ocular Surface
Conditions: Dry Eye Syndromes;   Sjogren's Syndrome
Intervention:
17 Recruiting Effects of Conventional Dry Eye Treatments on the Ocular Surface Response to Low Humidity Environment in Patients With Keratoconjunctivitis Sicca
Conditions: Keratoconjunctivitis Sicca;   Dry Eye Syndrome
Intervention: Drug: dexamethasone, artificial tears
18 Recruiting A Study of Flt3-Ligand Levels in Sjögrens Syndrome
Condition: Sjogrens Syndrome
Intervention:
19 Recruiting Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease
Conditions: Primary Sjogren Syndrome;   Secondary Sjogren Syndrome;   Aqueous Deficient Dry Eye Disease;   Evaporative Dry Eye Disease
Interventions: Drug: Restasis;   Drug: Refresh Endura
20 Recruiting Evaluation of Salivary Gland Dysfunction
Conditions: Sjogren's Syndrome;   Xerostomia
Intervention:

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Indicates status has not been verified in more than two years