Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
39 studies found for:    Open Studies | "Lacrimal Apparatus Diseases"
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Rank Status Study
1 Unknown  Pilot Study of a Homeopathic Therapy in Combination With Cyclosporin (Restasis) in the Treatment of Dry Eye Disease
Condition: Dry Eye Syndromes
Interventions: Drug: euphrasia based homeopathic therapy and cyclosporin;   Drug: cyclosporin solution
2 Not yet recruiting Evaluation of the Reproducibility Inter-observer of the Ultrasound Anomalies of the Salivary Glands in Sjogren's Disease
Condition: Sjogren's Disease
Intervention: Procedure: Ultrasound
3 Unknown  Rebamipide for the Treatment of Xerostomia in sjögren Syndrome
Condition: Improving Symptoms of Dry Mouth in Sjőgren's Syndrome
Intervention: Drug: Rebamipide
4 Recruiting Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis Sicca
Conditions: Keratoconjunctivitis Sicca;   Dry Eye Disease
Interventions: Drug: OTX-101 0.05%;   Drug: OTX-101 0.09%;   Drug: Vehicle
5 Recruiting Evaluation of Salivary Gland Dysfunction
Conditions: Sjogren's Syndrome;   Xerostomia
Intervention:
6 Recruiting Laser Therapy to Treat the Dry Mouth of Sjogren's Syndrome
Conditions: KERATOCONJUNCTIVITIS SICCA;   XEROSTOMIA;   SICCA SYNDROME;   PRIMARY SJOGREN SYNDROME
Interventions: Device: Laser 3R 790nm infrared Ga AIAs;   Device: Laser 3R 790 nm infrared  GaAIAs
7 Recruiting Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease
Conditions: Primary Sjogren Syndrome;   Secondary Sjogren Syndrome;   Aqueous Deficient Dry Eye Disease;   Evaporative Dry Eye Disease
Interventions: Drug: Restasis;   Drug: Refresh Endura
8 Not yet recruiting The Effect of Eyelid Surgery on Dry Eye - a Prospective Study
Conditions: Dry Eye Syndrome;   Ptosis;   Dermatochalasis
Intervention:
9 Recruiting Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2)
Condition: Chronic Graft-versus-host Disease
Interventions: Drug: R348 Ophthalmic Solution, 0.2%;   Drug: R348 Ophthalmic Solution, 0.5%;   Other: Placebo Ophthalmic Solution
10 Recruiting Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Primary Sjögren's Syndrome
Condition: Primary Sjögren's Syndrome
Interventions: Drug: CFZ533 active;   Drug: CFZ533 placebo
11 Unknown  A Placebo Controlled Double Masked Clinical Assessment Study of Essential Fatty Acid Supplement and Its Effect on Patients With Apparent Aqueous Deficient Dry Eye Syndrome
Condition: Dry Eye Syndrome
Intervention: Drug: Essential fatty acid supplement
12 Recruiting Salivary Biomarkers for Sjögren's Syndrome Detection
Condition: Sjögren's Syndrome
Intervention:
13 Recruiting Efficacy and Safety of Abatacept in Patients With Primary Sjögren's Syndrome
Condition: Sjögren's Syndrome
Intervention: Drug: Abatacept SC
14 Recruiting Evaluation of the Safety and Effectiveness of the Oculeve Intranasal Lacrimal Neurostimulator in Patients With Dry Eye
Condition: Dry Eye Syndromes
Intervention: Device: Oculeve Intranasal Lacrimal Neurostimulator
15 Recruiting Efficacy of Tocilizumab in Primary Sjögren's Syndrome.
Condition: Primary Sjögren's Syndrome (pSS)
Interventions: Drug: Tocilizumab;   Drug: Placebo
16 Recruiting Effects of Sustained Reading on the Ocular Surface
Conditions: Dry Eye Syndromes;   Sjogren's Syndrome
Intervention:
17 Unknown  Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye
Conditions: Dry Eye;   Sjogren's Syndrome;   Graft vs. Host Disease
Intervention: Drug: Thymosin Beta 4 eye drops vs. vehicle
18 Recruiting Pilot Study to Evaluate SYL1001 Safety and Effect in Patients With Ocular Pain
Conditions: Ocular Pain;   Dry Eye Syndrome
Interventions: Drug: SYL1001;   Drug: Placebo
19 Not yet recruiting A Phase 2a, Randomized, Placebo Controlled, Study to Evaluate the Safety and Efficacy of AMG 557/MEDI5872 in Primary Sjögren's Syndrome
Condition: Primary Sjögren's Syndrome
Interventions: Biological: AMG 557/MEDI5872;   Biological: Placebo
20 Recruiting Evaluation of the Efficacy and the Mechanism of Chinese Herbal Formula SS-1 for Sjögren's Syndrome
Condition: Sjögren's Syndrome
Interventions: Drug: SS-1;   Drug: Placebo

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Indicates status has not been verified in more than two years