91 studies found for:    Open Studies | "Lacrimal Apparatus Diseases"
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1 Not yet recruiting Innovative Imaging of the Conjunctiva, Cornea, and Ocular Adnexa : Study of a Handheld in Vivo Confocal Microscope and of a Fluorescent in Vivo Confocal Microscope
Conditions: Corneal Disease;   Blepharitis;   Lacrimal Apparatus Diseases;   Microscopy, Confocal
Interventions: Device: Handheld IVCM Vivascope 3000 (Caliber/Mavig) anesthesic eyedrop : oxybuprocaïne Thea 1,6 mg/0,4 ml;   Device: Multifluorescence IVCM vivascope 1500 ML (Caliber/Mavig);   Procedure: microangiography
2 Unknown  Pilot Study of a Homeopathic Therapy in Combination With Cyclosporin (Restasis) in the Treatment of Dry Eye Disease
Condition: Dry Eye Syndromes
Interventions: Drug: euphrasia based homeopathic therapy and cyclosporin;   Drug: cyclosporin solution
3 Not yet recruiting Clinical Evaluation of Systane® Balance in Dry Eye Subjects
Condition: Dry Eye
Intervention: Other: Propylene Glycol 0.6% eye drops
4 Recruiting Tolerability, Safety and Efficacy of Lubricin (150 µg/ml) Eye Drops Versus Sodium Hyaluronate (HA) 0.18% Eye Drops in Patients With Moderate Dry Eye (DE)
Condition: Dry Eye Syndrome
Interventions: Device: Lubricin;   Device: Sodium Hyaluronate
5 Recruiting A Phase III Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome
Condition: Dry Eye With Sjögren's Syndrome
Interventions: Drug: KCT-0809 ophthalmic solution;   Drug: Placebo
6 Recruiting An Extension Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome
Condition: Dry Eye With Sjögren's Syndrome
Intervention: Drug: KCT-0809 ophthalmic solution
7 Recruiting A Long-term Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome
Condition: Dry Eye With Sjögren's Syndrome
Intervention: Drug: KCT-0809 ophthalmic solution
8 Not yet recruiting Study of Pharmacodynamic Effects of VAY736 in Patients With Primary Sjögren's Syndrome
Condition: Primary Sjögren's Syndrome
Interventions: Drug: VAY736 lower dose;   Drug: VAY736 higher dose
9 Recruiting A Phase II Study With Low-dose Recombinant Human IL-2 for the Treatment of Primary Sjögren's Syndrome
Condition: Primary Sjögren's Syndrome
Interventions: Drug: hrIL-2 active;   Drug: hrIL-2 placebo
10 Not yet recruiting Dose-finding Study to Assess the Safety and Effect of SYL1001 in Patients With Ocular Pain
Conditions: Ocular Pain;   Dry Eye Syndrome
Interventions: Drug: SYL1001;   Drug: Placebo
11 Recruiting A Study to Compare a New Eye Drop Formulation With Systane® Gel Drops and Genteal® Lubricant Gel Drops for Moderate to Severe Dry Eye Relief
Condition: Dry Eye Syndromes
Interventions: Drug: Carboxymethylcellulose Sodium Based Eye Drops;   Drug: Systane® Gel Drops;   Drug: Genteal® Lubricant Gel Drops
12 Recruiting Pregnancy and Medically Assisted Conception in Rare Diseases
Conditions: Rheumatoid Arthritis;   Spondyloarthritis;   Psoriatic Arthritis;   Systemic Lupus Erythematosus;   Antiphospholipid Syndrome;   Sjogren Syndrome;   Scleroderma;   Myositis;   Vasculitis;   Mastocytosis;   Various Autoimmune and/or Systemic and/or Rare Diseases
Intervention:
13 Recruiting Clinical Evaluation Following Use of SYSTANE® ULTRA in the Management of Dry Eye
Condition: Dry Eye Syndrome
Intervention: Drug: SYSTANE® ULTRA Lubricant Eye Drops
14 Recruiting Safety, Efficacy, Tolerability and Pharmacokinetics of AGN-223575 Ophthalmic Suspension in Patients With Dry Eye Disease
Condition: Dry Eye Syndromes
Interventions: Drug: AGN-223575 ophthalmic solution;   Drug: AGN-223575 vehicle ophthalmic solution
15 Not yet recruiting Three Dimension Tomography of Eye Structures by White Light Imaging Device
Conditions: Healthy Subjects;   Moderate to Severe Keratoconjunctivitis Sicca (KCS);   Dry Eye Syndrome (DES)
Intervention: Device: None invasive imaging of the tear film (AdOM)
16 Recruiting Dry Eye Treatment With Artificial Tears
Condition: Dry Eye
Interventions: Other: Hypromellose 0.15%;   Other: Hypromellose 0.4%;   Other: Carboxymethylcellulose;   Other: Liposomal Spray
17 Not yet recruiting Safety, Tolerability and Systemic Pharmacokinetics of AGN-232411 in Healthy Participants and Participants With Dry Eye
Conditions: Healthy Volunteers;   Dry Eye Syndromes
Interventions: Drug: AGN-232411;   Drug: AGN-232411 Vehicle
18 Recruiting Tear Osmolarity Clinical Utility in Dry Eye Disease
Condition: Dry Eye
Interventions: Other: Tear supplement;   Other: Tear supplement 2;   Dietary Supplement: Omega 3 nutrition supplement;   Device: Eye bag;   Other: Saline
19 Recruiting A Study of Topical NS2 Cream to Treat Ichthyosis in Sjögren-Larsson Syndrome (SLS)
Condition: Sjögren-Larsson Syndrome
Interventions: Drug: Active topical NS2 1% dermatologic cream;   Drug: Vehicle placebo 0.0% NS2 dermatologic cream
20 Not yet recruiting Multicenter Trial Evaluating Quality of Tears Produced by Nasal Neurostimulation
Condition: Dry Eye Syndromes
Intervention: Device: Oculeve Intranasal Lacrimal Neurostimulator

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Indicates status has not been verified in more than two years