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21 studies found for:    Open Studies | "Hyperlipoproteinemia Type II"
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Rank Status Study
1 Not yet recruiting A Study of ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia
Interventions: Drug: ALN-PCSSC;   Drug: Standard of Care
2 Recruiting An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia
Condition: Hypercholesterolaemia
Interventions: Drug: alirocumab SAR236553 (REGN727);   Drug: statins;   Drug: ezetimibe;   Drug: cholestyramine;   Drug: fenofibrate;   Drug: omega-3 fatty acids;   Drug: nicotinic acid
3 Recruiting Developing and Implementing Familial Hypercholesterolemia Registry
Condition: Familial Hypercholesterolemia
Intervention: Other: Cascade
4 Recruiting Long Term Post Marketing Specified Drug Use Result Survey for Evolocumab in Japan
Conditions: Hypercholesterolemia;   Familial Hypercholesterolemia
Intervention: Other: No intervention
5 Recruiting Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)
Condition: Hypercholesteremia
Interventions: Drug: Gemcabene 300 mg;   Drug: Gemcabene 600 mg;   Drug: Gemcabene 900 mg
6 Recruiting The Spanish Familial Hypercholesterolaemia Cohort Study
Condition: Familial Hypercholesterolaemia
Intervention:
7 Recruiting A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Genetic: AAV directed hLDLR gene therapy
8 Recruiting Open Label Study to Evaluate Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Pediatric Subjects (10 to 17 Years of Age) With Heterozygous Familial Hypercholesterolemia (HeFH) or Homozygous Familial Hypercholesterolemia (HoFH).
Condition: Familial Hypercholesterolemia
Intervention: Biological: evolocumab (AMG 145)
9 Recruiting Trial Assessing Efficacy, Safety and Tolerability of PCSK9 Inhibition in Paediatric Subjects With Genetic LDL Disorders
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: Evolocumab;   Drug: Placebo
10 Recruiting Study of REGN1500 in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: REGN1500
11 Recruiting Russian Familial Hypercholesterolemia Registry
Condition: Familial Hypercholesterolemia
Intervention:
12 Recruiting French Observatory of Familial Hypercholesterolemia in Cardiology
Condition: Familial Hypercholesterolemia
Intervention:
13 Recruiting The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository
Condition: Homozygous Familial Hypercholesterolemia
Intervention:
14 Recruiting Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada
Conditions: Familial Hypercholesterolemia;   Lipid Disorder
Intervention:
15 Recruiting Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Subjects With Familial Hypercholesterolemia
Conditions: Hypertriglyceridemia;   Familial Hypercholesterolemia
Interventions: Drug: IONIS ANGPTL3-LRx;   Drug: Placebo (0.9%NaCl, water, riboflavin)
16 Recruiting MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR)
Condition: Familial Hypercholesterolemia - Heterozygous
Intervention:
17 Recruiting Atherosclerosis in Familial Hypercholesterolemia
Condition: Familial Hypercholesterolemia
Intervention: Other: CT coronary angiogram and carotid ultrasound
18 Not yet recruiting Effects of Lomitapide on Carotid and Aortic Atherosclerosis
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: Lomitapide
19 Not yet recruiting Lp(a) and Aortic Valve Calcification
Condition: Heterozygous Familial Hypercholesterolemia
Intervention:
20 Recruiting Familial Hypercholesterolemia Amongst Patients With Acute Coronary Syndrome
Conditions: Familial Hypercholesterolemia;   Cardiac Event;   Acute Coronary Syndrome
Intervention: Other: Registry

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Study has passed its completion date and status has not been verified in more than two years.