27 studies found for:    Open Studies | "Hyperlipoproteinemia Type II"
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Open Studies | "Hyperlipoproteinemia Type II" (27 records)
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Rank Status Study
1 Not yet recruiting Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering Therapy
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: Lomitapide
2 Not yet recruiting Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, Germany
Conditions: Type 1 Diabetes;   Familial Hypercholesterolemia
Intervention:
3 Not yet recruiting A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-833)
Conditions: Hypercholesterolemia;   Familial Hypercholesterolemia
Interventions: Drug: Ezetimibe;   Drug: Rosuvastatin
4 Recruiting Postprandial Response After Intake of Meals With Different Fatty Acid Composition
Conditions: Healthy;   Familial Hypercholesterolemia
Interventions: Dietary Supplement: SFA muffin;   Dietary Supplement: PUFA muffin
5 Not yet recruiting Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)
Condition: Hypercholesteremia
Interventions: Drug: Gemcabene 300 mg;   Drug: Gemcabene 600 mg;   Drug: Gemcabene 900 mg
6 Recruiting Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Subjects With Familial Hypercholesterolemia
Conditions: Hypertriglyceridemia;   Familial Hypercholesterolemia
Interventions: Drug: IONIS ANGPTL3-LRx;   Drug: Placebo (0.9%NaCl, water, riboflavin)
7 Recruiting The Spanish Familial Hypercholesterolaemia Cohort Study
Condition: Familial Hypercholesterolaemia
Intervention:
8 Recruiting A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Genetic: AAV directed hLDLR gene therapy
9 Not yet recruiting Open Label Study to Evaluate Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Pediatric Subjects (10 to 17 Years of Age) With Heterozygous Familial Hypercholesterolemia (HeFH) or Homozygous Familial Hypercholesterolemia (HoFH).
Condition: Familial Hypercholesterolemia
Intervention: Biological: evolocumab (AMG 145)
10 Recruiting Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C)
Conditions: Atherosclerotic Cardiovascular Disease;   Familial Hypercholesterolemia;   Diabetes
Intervention: Drug: ALN-PCSSC
11 Recruiting MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR)
Condition: Familial Hypercholesterolemia - Heterozygous
Intervention:
12 Recruiting Atherosclerosis in Familial Hypercholesterolemia
Condition: Familial Hypercholesterolemia
Intervention: Other: CT coronary angiogram and carotid ultrasound
13 Not yet recruiting Effects of Lomitapide on Carotid and Aortic Atherosclerosis
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: Lomitapide
14 Recruiting Trial Assessing Efficacy, Safety and Tolerability of PCSK9 Inhibition in Paediatric Subjects With Genetic LDL Disorders
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: Evolocumab;   Drug: Placebo
15 Recruiting Study of REGN1500 in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: REGN1500
16 Recruiting Russian Familial Hypercholesterolemia Registry
Condition: Familial Hypercholesterolemia
Intervention:
17 Recruiting French Observatory of Familial Hypercholesterolemia in Cardiology
Condition: Familial Hypercholesterolemia
Intervention:
18 Recruiting Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada
Conditions: Familial Hypercholesterolemia;   Lipid Disorder
Intervention:
19 Recruiting Study of Awareness and Detection of Familial Hypercholesterolemia
Condition: Hypercholesterolemia
Intervention:
20 Unknown  Gene Analysis and Treatment Optimization in Chinese Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Other: Gene analysis

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Indicates status has not been verified in more than two years