Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
91 studies found for:    Open Studies | "Hypercholesterolemia"
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Rank Status Study
21 Not yet recruiting Study of REGN1500 in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: REGN1500
22 Not yet recruiting Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: Alirocumab;   Drug: Placebo
23 Not yet recruiting Probiotic BIO-25 as a Supplement to Statins for the Treatment of Hypercholesterolemia
Condition: Hypercholesterolemia
Intervention: Other: Food supplement
24 Recruiting Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders
Condition: Severe Familial Hypercholesterolemia
Intervention: Biological: Evolocumab (AMG145)
25 Unknown  Addition of Ezetimibe (Ezetrol®) to Ongoing Therapy With Rosuvastatin (Crestor®) in HIV Positive Patients Not Reaching Cholesterol Targets
Conditions: Hypercholesterolemia;   HIV Infections
Interventions: Drug: Ezetimibe;   Drug: Rosuvastatin (standard care)
26 Unknown  Soy Food Intervention Trial
Condition: Familial Hypercholesterolemia
Interventions: Dietary Supplement: soy protein diet;   Dietary Supplement: rapeseed oil
27 Not yet recruiting A Clinical Trial for Evaluation of Adequate Dose and Safety of DW-3102 in Hypercholesterolemia Patients
Condition: Hypercholesterolemia
Intervention: Drug: DW-3102
28 Recruiting The Efficacy and Safety of a Combination Therapy of Rosuvastatin and Ezetimibe Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients
Condition: Hypercholesterolemia
Intervention: Drug: Rosuvastatin/Ezetimibe
29 Recruiting To Compare the Effect of Concomitant Administration of Probucol and Cilostazol With Probucol Single Treatment on the Atherosclerosis Related Markers (Including the Thickness of the Achilles Tendon) and Evaluate Safety (Based on Atorvastatin Treatment) in Severe Hypercholesterolemia Subject
Condition: Severe Hypercholesterolemia
Intervention: Drug: Atorvastatin, Probucol, Cilostazol
30 Recruiting Evaluation of ETC-1002 vs Placebo in Patients Receiving Ongoing Statin Therapy
Condition: Hypercholesterolemia
Interventions: Drug: ETC-1002;   Drug: Placebo
31 Recruiting Open Label Study of Long Term Safety Evaluation of Alirocumab
Condition: Hypercholesterolemia
Intervention: Drug: Alirocumab SAR236553 (REGN727)
32 Unknown  Effect of Rapeseed Oil and Sunflower Oil
Condition: Familial Hypercholesterolemia
Interventions: Dietary Supplement: rapeseed oil;   Dietary Supplement: sunflower oil
33 Unknown  Effect of Omega-3 Fatty Acid on Endothelial Function
Condition: Familial Hypercholesterolemia
Interventions: Drug: Omega-3;   Drug: placebo
34 Recruiting Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering Therapy
Condition: Familial Hypercholesterolemia - Homozygous
Intervention: Drug: lomitapide
35 Recruiting Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Conditions: Infection;   Hypertension;   Anesthesia;   Pain;   Reflux;   Nausea;   Edema;   Hyperlipidemia;   Hypotension;   Hypercholesterolemia;   Sedation;   Anxiolysis;   Benzodiazepine Withdrawal;   Bipolar Disorder;   Autistic Disorder;   Schizophrenia;   Influenza Treatment or Prophylaxis;   Acute Decompensated Heart Failure;   Stable Angina;   Life-threatening Fungal Infections;   Nosocomial Pneumonia;   Community Acquired Pneumonia;   Acute Bacterial Exacerbation of Chronic Bronchitis;   Complicated Skin and Skin Structure Infections;   Uncomplicated Skin and Skin Structure Infections;   Chronic Bacterial Prostatitis;   Complicated Urinary Tract Infections;   Acute Pyelonephritis;   Uncomplicated Urinary Tract Infections;   Inhalational Anthrax (Post-Exposure);   Infantile Hemangioma
Intervention: Drug: Ampicillin
36 Unknown  The Anti-Diabetic and Cholesterol-Lowering Effects of Cinnamon and Cassia Bark
Conditions: Type 2 Diabetes;   Hypercholesterolemia
Interventions: Dietary Supplement: Cinnamonforce;   Dietary Supplement: Placebo
37 Unknown  Tolerability and Lipid Lowering Effect of Weekly/Biweekly Crestor in Statin Intolerant Patients Treated With Zetia
Condition: Hypercholesterolemia
Interventions: Drug: Rosuvastatin;   Drug: Ezetimibe
38 Unknown  The Effects of Lowering Low-density Lipoprotein Cholesterol Levels to New Targets on Cardiovascular Complications in Peritoneal Dialysis Patients
Condition: Hypercholesterolemia
Intervention: Other: LDL-cholesterol
39 Recruiting Genetically Guided Statin Therapy
Conditions: Hypercholesterolemia;   HMG COA Reductase Inhibitor Adverse Reaction
Interventions: Genetic: Reporting for SLCO1B1*5 allele at randomization;   Genetic: Reporting for SLCO1B1*5 allele at the end;   Genetic: Genetic testing for SLCO1B1*5 allele
40 Not yet recruiting Patient and Provider Assessment of Lipid Management Registry
Conditions: Hyperlipidemia;   Hypercholesterolemia;   Cardiovascular Disease;   Diabetes;   Chronic Kidney Disease (CKD);   Hypertension;   Smoking;   Myocardial Infarction (MI);   Unstable Angina;   Angina;   Coronary Artery Disease (CAD);   Stroke;   Transient Ischemic Attack (TIA);   Carotid Stenosis;   Peripheral Arterial Disease;   Atherosclerosis;   Claudication
Intervention:

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Indicates status has not been verified in more than two years