24 studies found for:    Open Studies | "Herpes Simplex"
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Rank Status Study
1 Not yet recruiting Herpes Simplex Reactivation in Adult Critical Care Patients
Conditions: Herpes Simplex I;   Herpes Simplex II
Intervention: Other: No intervention will be performed
2 Recruiting The Flocked Swab and the Traditional Fiber Swab for the Diagnosis of the Herpes Simplex Epithelial Keratitis
Condition: Herpes Simplex Keratitis
Intervention: Procedure: Corneal sampling
3 Recruiting Identification of Herpes Simplex Virus (HSV) Shedding in the Female Genital Tract of Pregnant and Nonpregnant Women by GeneXpert PCR, Routine PCR, and Culture
Condition: Herpes Simplex Virus
Intervention: Device: Genexpert assay
4 Not yet recruiting A Safety and Dose-Determining Study of CMX001 In Infants With Neonatal Herpes Simplex Virus (HSV) Infection Involving the Central Nervous System (CNS Disease)
Condition: Herpes Simplex Virus
Interventions: Drug: Novel Antiviral Drug;   Drug: Placebo
5 Unknown  Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System
Condition: Herpes Simplex
Intervention: Drug: acyclovir
6 Unknown  Can Valacyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2?
Conditions: HIV Infections;   Herpes Simplex
Interventions: Drug: Valacyclovir;   Drug: Placebo
7 Unknown  30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteers
Condition: Herpes Simplex
Interventions: Drug: valacyclovir hydrochloride;   Drug: placebo;   Drug: valacyclovir plus aspirin
8 Recruiting Evaluation of the HSV 1 & 2 Assay in Specimens From Symptomatic Subjects
Condition: Herpes Simplex Infections
9 Not yet recruiting Antiviral Prophylaxis in a Burn Population
Condition: Herpes Simplex
Intervention: Drug: Acyclovir
10 Unknown  Improving Blood Safety and HIV Testing in Brazil
Conditions: HIV;   Herpes Simplex 2;   Hepatitis C;   Hepatitis B;   Chagas Disease
Interventions: Behavioral: HIV Counseling and Testing;   Behavioral: Blood Donation
11 Recruiting Interferon Responses in Eczema Herpeticum
Conditions: Atopic Dermatitis;   Eczema Herpeticum;   Herpes Simplex Infections;   Eczema Vaccinatum
12 Not yet recruiting Study to Evaluate Safety, Tolerability, and Pharmacokinetics of UB-621 in Healthy Volunteers
Condition: Herpes Simplex Virus Infection
Intervention: Drug: UB-621
13 Not yet recruiting Evaluating New Formulation of Therapeutic HSV-2 Vaccine
Condition: Genital Herpes Simplex Type 2
Interventions: Biological: Matrix-M2;   Biological: GEN-003;   Drug: Placebo
14 Unknown  A Phase I Study of Recombinant hGM-CSF Herpes Simplex Virus to Treat Cancer
Conditions: Melanoma;   Liver Cancer;   Pancreatic Cancer;   Lung Cancer
Intervention: Biological: Recombinant hGM-CSF Herpes Simplex Virus Injection
15 Recruiting A Double-Blind, Randomized, Placebo-Controlled Study of Topical VDO for the Treatment of Herpes Simplex Labialis
Condition: Herpes Labialis
Interventions: Drug: VDO gel;   Drug: placebo
16 Recruiting Comparative Safety and Efficacy of Two Antiviral Treatments in the Treatment of Recurrent Herpes Simplex Labialis
Condition: Herpes Labialis
Interventions: Drug: Acyclovir 5 percent (Perrigo);   Drug: Acyclovir 5 percent (Reference);   Drug: Placebo cream
17 Recruiting Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery
Conditions: Recurrent Childhood Anaplastic Astrocytoma;   Recurrent Childhood Anaplastic Oligoastrocytoma;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Giant Cell Glioblastoma;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Gliomatosis Cerebri;   Recurrent Childhood Gliosarcoma
Interventions: Biological: oncolytic HSV-1716;   Drug: dexamethasone;   Procedure: therapeutic conventional surgery;   Other: laboratory biomarker analysis
18 Recruiting HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors
Conditions: Rhabdomyosarcoma;   Osteosarcoma;   Ewing Sarcoma;   Soft Tissue Sarcoma;   Neuroblastoma;   Wilms Tumor;   Malignant Peripheral Nerve Sheath Tumor;   Clival Chordoma;   Non-CNS Solid Tumors
Intervention: Biological: HSV1716
19 Recruiting Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma.
Condition: Malignant Pleural Mesothelioma
Intervention: Biological: HSV1716 Intra-pleural delivery
20 Recruiting Safety, Tolerability and Therapeutic Efficacy of Topical ZEP-3 Ointment (1.0%) for the Treatment of Cold Sores
Condition: Herpes Labialis
Interventions: Drug: ZEP-3 ointment 1.0%;   Drug: Acyclovir cream 5%

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Indicates status has not been verified in more than two years