24 studies found for:    Open Studies | "Herpes Simplex"
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Rank Status Study
1 Not yet recruiting Herpes Simplex Reactivation in Adult Critical Care Patients
Conditions: Herpes Simplex I;   Herpes Simplex II
Intervention: Other: No intervention will be performed
2 Recruiting Identification of Herpes Simplex Virus (HSV) Shedding in the Female Genital Tract of Pregnant and Nonpregnant Women by GeneXpert PCR, Routine PCR, and Culture
Condition: Herpes Simplex Virus
Intervention: Device: Genexpert assay
3 Not yet recruiting A Safety and Dose-Determining Study of CMX001 In Infants With Neonatal Herpes Simplex Virus (HSV) Infection Involving the Central Nervous System (CNS Disease)
Condition: Herpes Simplex Virus
Interventions: Drug: Novel Antiviral Drug;   Drug: Placebo
4 Unknown  Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System
Condition: Herpes Simplex
Intervention: Drug: acyclovir
5 Recruiting Palatability Testing of a New Paediatric Formulation of Valacyclovir
Conditions: Varicella Zoster Virus Infection;   Herpes Simplex Virus Infection
Intervention: Drug: Valacyclovir
6 Unknown  Can Valacyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2?
Conditions: HIV Infections;   Herpes Simplex
Interventions: Drug: Valacyclovir;   Drug: Placebo
7 Recruiting Vaginal Antibody Safety Trial: Safety Study of Monoclonal Antibodies to Reduce the Vaginal Transmission of Herpes Simplex Virus (HSV) and Human Immunodeficiency Virus (HIV)
Conditions: HIV;   Herpes Simplex Infections
Interventions: Drug: MB66;   Drug: Placebo Film
8 Unknown  30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteers
Condition: Herpes Simplex
Interventions: Drug: valacyclovir hydrochloride;   Drug: placebo;   Drug: valacyclovir plus aspirin
9 Recruiting Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Conditions: Infection;   Hypertension;   Pain;   Reflux;   Edema;   Hyperlipidemia;   Hypotension;   Hypercholesterolemia;   Sedation;   Anxiolysis;   Benzodiazepine Withdrawal;   Bipolar Disorder;   Autistic Disorder;   Schizophrenia;   Influenza Treatment or Prophylaxis;   Acute Decompensated Heart Failure;   Stable Angina;   Life-threatening Fungal Infections;   Nosocomial Pneumonia;   Community Acquired Pneumonia;   Acute Bacterial Exacerbation of Chronic Bronchitis;   Complicated Skin and Skin Structure Infections;   Uncomplicated Skin and Skin Structure Infections;   Chronic Bacterial Prostatitis;   Complicated Urinary Tract Infections;   Acute Pyelonephritis;   Uncomplicated Urinary Tract Infections;   Inhalational Anthrax (Post-Exposure);   Infantile Hemangioma;   Withdrawal;   Inflammation;   Bacterial Septicemia;   Cytomegalovirus Retinitis;   Herpes Simplex Virus;   Adenovirus;   Brain Swelling;   Airway Swelling;   Adrenal Insufficiency;   Anxiety;   Nausea;   Vomiting;   Convulsions;   Muscle Spasms;   Seizures;   Epilepsy;   Bartonellosis;   Brucellosis;   Cholera;   Plague;   Psittacosis;   Q Fever;   Relapsing Fever;   Rocky Mountain Spotted Fever;   Trachoma;   Tularemia;   Typhus Fever;   Bronchospasm;   Cardiac Arrest;   Hypersensitivity Reaction;   Cyanide Poisoning;   Acute Bacterial Sinusitis;   Bacterial Meningitis;   Sepsis;   Gastroparesis;   Opioid Addiction;   Migraines;   Headaches
Intervention: Drug: The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
10 Recruiting Clinical Evaluation of the Sentosa SA HSV1/2 Qualitative PCR Test
Condition: Herpes Simplex
Intervention: Device: Vela Sentosa SA HSV1/2 Qualitative PCR Test
11 Unknown  Improving Blood Safety and HIV Testing in Brazil
Conditions: HIV;   Herpes Simplex 2;   Hepatitis C;   Hepatitis B;   Chagas Disease
Interventions: Behavioral: HIV Counseling and Testing;   Behavioral: Blood Donation
12 Recruiting Interferon Responses in Eczema Herpeticum
Conditions: Atopic Dermatitis;   Eczema Herpeticum;   Herpes Simplex Infections;   Eczema Vaccinatum
Intervention:
13 Recruiting Study to Evaluate Safety, Tolerability, and Pharmacokinetics of UB-621 in Healthy Volunteers
Condition: Herpes Simplex Virus Infection
Intervention: Drug: UB-621
14 Unknown  A Phase I Study of Recombinant hGM-CSF Herpes Simplex Virus to Treat Cancer
Conditions: Melanoma;   Liver Cancer;   Pancreatic Cancer;   Lung Cancer
Intervention: Biological: Recombinant hGM-CSF Herpes Simplex Virus Injection
15 Recruiting Comparative Safety and Efficacy of Two Antiviral Treatments in the Treatment of Recurrent Herpes Simplex Labialis
Condition: Herpes Labialis
Interventions: Drug: Acyclovir 5 percent (Perrigo);   Drug: Acyclovir 5 percent (Reference);   Drug: Placebo cream
16 Recruiting Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery
Conditions: Recurrent Childhood Anaplastic Astrocytoma;   Recurrent Childhood Anaplastic Oligoastrocytoma;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Giant Cell Glioblastoma;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Gliomatosis Cerebri;   Recurrent Childhood Gliosarcoma
Interventions: Biological: oncolytic HSV-1716;   Drug: dexamethasone;   Procedure: therapeutic conventional surgery;   Other: laboratory biomarker analysis
17 Recruiting HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors
Conditions: Rhabdomyosarcoma;   Osteosarcoma;   Ewing Sarcoma;   Soft Tissue Sarcoma;   Neuroblastoma;   Wilms Tumor;   Malignant Peripheral Nerve Sheath Tumor;   Clival Chordoma;   Non-CNS Solid Tumors
Intervention: Biological: HSV1716
18 Recruiting Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma.
Condition: Malignant Pleural Mesothelioma
Intervention: Biological: HSV1716 Intra-pleural delivery
19 Not yet recruiting Should We Use Oral Valacyclovir in Acute Herpetic Gingivostomatitis in Children?
Condition: Herpetic Gingivostomatitis
Interventions: Drug: Valacyclovir;   Drug: placebo
20 Not yet recruiting Study of a New Topical Natural Health Product for the Treatment of Herpes Labialis
Condition: Herpes Labialis
Interventions: Other: BOR15001L7;   Other: Placebo

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Indicates status has not been verified in more than two years