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546 studies found for:    Open Studies | "Glioma"
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Rank Status Study
1 Recruiting A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Conditions: Pilomyxoid Astrocytoma;   Pilocytic Astrocytoma;   Glioma, Astrocytic;   Optic Nerve Glioma;   Pleomorphic Xanthoastrocytoma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Gliosarcoma;   Diffuse Intrinsic Pontine Glioma;   DIPG;   Low-grade Glioma;   Brainstem Glioma
Interventions: Drug: Mebendazole;   Drug: Vincristine;   Drug: Carboplatin;   Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
2 Recruiting Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma
Conditions: Oligodendroglioma;   Astrocytoma, Grade II;   Glioma, Astrocytic;   Glioma;   Malignant Glioma;   Oligoastrocytoma, Mixed
Interventions: Biological: GBM6-AD and poly-ICLC before and after surgery;   Biological: GBM6-AD and poly-ICLC after surgery only
3 Not yet recruiting A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)
Conditions: Glioma;   Malignant Glioma;   Astrocytoma, Grade II;   Oligodendroglioma;   Glioma, Astrocytic;   Oligoastrocytoma, Mixed
Interventions: Biological: IMA950;   Biological: poly-ICLC;   Biological: Varlilumab
4 Recruiting Proton Radiation Therapy for Gliomas
Conditions: Low Grade Glioma;   WHO Grade 3 Glioma With IDH1 Mutation;   WHO Grade 3 Glioma With 1p/19q Codeletion
Intervention: Radiation: Proton radiation
5 Recruiting Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22
Conditions: Glioblastoma Multiforme;   Fibrillary Astrocytoma of Brain;   Glioma of Brainstem;   Anaplastic Astrocytoma;   Pilomyxoid Astrocytoma;   Mixed Oligodendroglioma-Astrocytoma;   Brain Stem Glioma;   Diffuse Intrinsic Pontine Glioma
Intervention: Drug: SIACI of Erbitux and Bevacizumab
6 Recruiting A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
Conditions: Newly Diagnosed Pediatric Pontine Glioma.;   Newly Diagnosed Pediatric High Grade Glioma.;   Recurrent Pediatric High Grade Glioma.;   Recurrent Pediatric Low Grade Glioma.
Interventions: Biological: HLA-A2 restricted glioma antigen peptides vaccine;   Biological: Poly-ICLC
7 Recruiting Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Brainstem Glioma
8 Recruiting Dendritic Cell Vaccine For Malignant Glioma and Glioblastoma Multiforme in Adult and Pediatric Subjects
Conditions: Malignant Glioma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Biological: Dendritic Cell Vaccine;   Biological: Tumor Lysate;   Other: Imiquimod;   Procedure: Leukapheresis
9 Recruiting Rotating Frame Relaxation and Diffusion Weighted Imaging of Human Gliomas
Conditions: Low Grade Glioma;   Malignant Glioma
10 Recruiting Treatment With AZD4547 for Recurrent Malignant Glioma Expressing FGFR-TACC Gene Fusion"
Conditions: Recurrent IDHwt Gliomas With FGFR3-TACC3 Fusion;   Recurrent IDHwt Gliomas With FGFR1-TACC1 Fusion
Intervention: Drug: AZD4547
11 Recruiting PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Conditions: Pediatric Recurrent Progressive Low-grade Gliomas;   Pediatric Progressive Low-grade Gliomas
Intervention: Drug: Everolimus
12 Recruiting Imiquimod and Tumor Lysate Vaccine Immunotherapy in Adults With High Risk or Recurrent Grade II Gliomas
Conditions: High Risk WHO Grade II Glioma;   Recurrent/Post-Chemotherapy WHO Grade II Glioma
Interventions: Biological: Tumor Lysate Vaccine;   Drug: Imiquimod
13 Recruiting FDOPA-PET/MRI for the Pre-operative Evaluation of Gliomas
Conditions: Glioma;   Malignant Glioma
Interventions: Drug: 6-[F-18]-Fluoro-L-3,4,-dihydroxyphenylalanine;   Device: PET/MRI;   Procedure: Surgical resection (standard of care)
14 Recruiting D2C7 for Adult Patients With Recurrent Malignant Glioma
Conditions: Glioblastoma;   Glioma;   Malignant Glioma;   Brain Tumor, Recurrent
Intervention: Drug: D2C7-IT
15 Recruiting 5-ALA in Recurrent Glioma
Condition: Glioma
Intervention: Drug: 5-ala
16 Recruiting Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype
Conditions: Glioma;   Recurrent Malignant Glioma
Intervention: Drug: Pembrolizumab
17 Not yet recruiting A Phase II Study of NovoTTF-100A Alone and With Temozolomide in Patients With Low-Grade Gliomas
Condition: Glioma
Interventions: Device: NovoTTF-100A;   Drug: Temozolomide
18 Recruiting First in Patient Study for PF-06840003 in Malignant Gliomas
Conditions: Oligodendroglioma;   Astrocytoma;   Malignant Glioma
Intervention: Drug: PF-06840003
19 Recruiting Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas
Conditions: Adult Anaplastic Astrocytoma;   Adult Anaplastic Ependymoma;   Adult Anaplastic Oligodendroglioma;   Adult Brain Stem Glioma;   Adult Diffuse Astrocytoma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Adult Oligodendroglioma;   Adult Pilocytic Astrocytoma;   Adult Pineal Gland Astrocytoma;   Adult Subependymal Giant Cell Astrocytoma;   Recurrent Adult Brain Tumor
Interventions: Radiation: Hyperfractionated radiation therapy;   Radiation: Stereotactic radiosurgery;   Drug: Alisertib;   Procedure: Quality-of-life assessment
20 Recruiting Phase I Trial of Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas
Condition: Malignant Glioma
Interventions: Radiation: Hypofractionated Stereotactic Irradiation (HFSRT);   Drug: Pembrolizumab;   Drug: Bevacizumab

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