498 studies found for:    Open Studies | "Glioma"
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1 Recruiting A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Conditions: Pilomyxoid Astrocytoma;   Pilocytic Astrocytoma;   Glioma, Astrocytic;   Optic Nerve Glioma;   Pleomorphic Xanthoastrocytoma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Gliosarcoma;   Diffuse Intrinsic Pontine Glioma;   DIPG;   Low-grade Glioma;   Brainstem Glioma
Interventions: Drug: Mebendazole;   Drug: Vincristine;   Drug: Carboplatin;   Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
2 Recruiting Proton Radiation Therapy for Gliomas
Conditions: Low Grade Glioma;   WHO Grade 3 Glioma With IDH1 Mutation;   WHO Grade 3 Glioma With 1p/19q Codeletion
Intervention: Radiation: Proton radiation
3 Recruiting A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
Conditions: Newly Diagnosed Pediatric Pontine Glioma.;   Newly Diagnosed Pediatric High Grade Glioma.;   Recurrent Pediatric High Grade Glioma.;   Recurrent Pediatric Low Grade Glioma.
Interventions: Biological: HLA-A2 restricted glioma antigen peptides vaccine;   Biological: Poly-ICLC
4 Recruiting AZD6244 in Children With Low-Grade Gliomas
Conditions: Optic Glioma;   Pilocytic Astrocytoma;   Low Grade Glioma;   Fibriullary Astrocytoma
Intervention: Drug: AZD6244
5 Recruiting Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Brainstem Glioma
Intervention:
6 Recruiting Dendritic Cell Vaccine For Malignant Glioma and Glioblastoma Multiforme in Adult and Pediatric Subjects
Conditions: Malignant Glioma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Biological: Dendritic Cell Vaccine;   Biological: Tumor Lysate;   Other: Imiquimod;   Procedure: Leukapheresis
7 Recruiting Rotating Frame Relaxation and Diffusion Weighted Imaging of Human Gliomas
Conditions: Low Grade Glioma;   Malignant Glioma
Intervention:
8 Recruiting Phase I/II Trial Of Super-Selective Intraarterial Infusion Of Erbitux and Bevacizumab For Treatment Of Relapsed/Refractory Intracranial Glioma In Patients Under 22 Years Of Age
Conditions: Glioblastoma Multiforme;   Fibrillary Astrocytoma of Brain;   Glioma of Brainstem;   Anaplastic Astrocytoma;   Pilomyxoid Astrocytoma;   Mixed Oligodendroglioma-Astrocytoma;   Brain Stem Glioma;   Diffuse Intrinsic Pontine Glioma;   High Grade Glioma
Intervention: Drug: SIACI of Erbitux (200 m/m2) and Bevacizumab(15 mg/kg)
9 Recruiting Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
Conditions: Diffuse Intrinsic Pontine Glioma;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Drug: Lenalidomide;   Radiation: XRT, 54-59.4 Gy
10 Recruiting PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Conditions: Pediatric Recurrent Progressive Low-grade Gliomas;   Pediatric Progressive Low-grade Gliomas
Intervention: Drug: Everolimus
11 Recruiting Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Conditions: Glioma;   Neurofibromatosis Type 1;   Recurrent Childhood Pilocytic Astrocytoma;   Recurrent Childhood Visual Pathway Glioma
Interventions: Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: Selumetinib
12 Recruiting Imiquimod and Tumor Lysate Vaccine Immunotherapy in Adults With High Risk or Recurrent Grade II Gliomas
Conditions: High Risk WHO Grade II Glioma;   Recurrent/Post-Chemotherapy WHO Grade II Glioma
Interventions: Biological: Tumor Lysate Vaccine;   Drug: Imiquimod
13 Not yet recruiting Administration of Ribociclib Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)
Conditions: High Grade Glioma;   Diffuse Intrinsic Pontine Glioma;   Bithalamic High Grade Glioma
Intervention: Drug: Ribociclib
14 Recruiting FDOPA-PET/MRI for the Pre-operative Evaluation of Gliomas
Conditions: Glioma;   Malignant Glioma
Interventions: Drug: 6-[F-18]-Fluoro-L-3,4,-dihydroxyphenylalanine;   Device: PET/MRI;   Procedure: Surgical resection (standard of care)
15 Recruiting D2C7 for Adult Patients With Recurrent Malignant Glioma
Conditions: Glioblastoma;   Glioma;   Malignant Glioma;   Brain Tumor, Recurrent
Intervention: Drug: D2C7-IT
16 Recruiting 5-ALA in Recurrent Glioma
Condition: Glioma
Intervention: Drug: 5-ala
17 Recruiting Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype
Conditions: Glioma;   Recurrent Malignant Glioma
Intervention: Drug: Pembrolizumab
18 Not yet recruiting A Phase II Study of NovoTTF-100A Alone and With Temozolomide in Patients With Low-Grade Gliomas
Condition: Glioma
Interventions: Device: NovoTTF-100A;   Drug: Temozolomide
19 Recruiting 18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapy
Conditions: Adult Anaplastic (Malignant) Meningioma;   Adult Anaplastic Astrocytoma;   Adult Anaplastic Ependymoma;   Adult Brain Stem Glioma;   Adult Choroid Plexus Neoplasm;   Adult Ependymoblastoma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Medulloblastoma;   Adult Mixed Glioma;   Adult Papillary Meningioma;   Adult Pineal Gland Astrocytoma;   Adult Pineoblastoma;   Adult Primary Melanocytic Lesion of Meninges;   Adult Supratentorial Primitive Neuroectodermal Tumor
Interventions: Drug: Fluorine F 18 Fluorodopa;   Procedure: Positron Emission Tomography;   Procedure: Computed Tomography;   Procedure: Perfusion Magnetic Resonance Imaging;   Procedure: Diffusion Weighted Imaging;   Radiation: Intensity-Modulated Radiation Therapy;   Drug: Temozolomide;   Other: Quality-of-Life Assessment
20 Recruiting Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas
Conditions: Adult Anaplastic Astrocytoma;   Adult Anaplastic Ependymoma;   Adult Anaplastic Oligodendroglioma;   Adult Brain Stem Glioma;   Adult Diffuse Astrocytoma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Adult Oligodendroglioma;   Adult Pilocytic Astrocytoma;   Adult Pineal Gland Astrocytoma;   Adult Subependymal Giant Cell Astrocytoma;   Recurrent Adult Brain Tumor
Interventions: Radiation: Hyperfractionated radiation therapy;   Radiation: Stereotactic radiosurgery;   Drug: Alisertib;   Procedure: Quality-of-life assessment

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