| 1 |
NCT03500354 |
Not yet recruiting
New |
Nutritional Drink in Gastroparesis |
|
- Dietary Supplement: Nutrient drink
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Tolerability will be measured by the Palatability Questionnaire at 2 days
- Tolerability will be measured by the Palatability Questionnaire at 7 days
- Tolerability will be measured by the Palatability Questionnaire at 4 weeks
- (and 5 more...)
|
20 |
All |
16 Years and older (Child, Adult, Senior) |
NCT03500354 |
IRB00157677 |
|
June 2018 |
May 2019 |
August 2019 |
April 17, 2018 |
April 17, 2018 |
|
- Johns Hopkins University
Baltimore, Maryland, United States
|
| 2 |
NCT02130622 |
Recruiting |
Study of Promethazine for Treatment of Diabetic Gastroparesis |
|
- Drug: Promethazine
- Drug: Sugar pill
|
Interventional |
Phase 2 |
- Dartmouth-Hitchcock Medical Center
- American College of Gastroenterology
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in patient-reported symptoms as measured by the Gastroparesis Cardinal Symptom Index score (GCSI, 14) from week 0 to week 4.
- Occurrence of adverse events
- Use of rescue medication
- The impact on work activity as measured by the Work Productivity and Activity Impairment Questionnaire. (WPAI).
|
24 |
All |
18 Years to 65 Years (Adult) |
NCT02130622 |
D14076 |
|
July 2014 |
December 2020 |
|
May 5, 2014 |
May 12, 2017 |
|
- Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States
|
| 3 |
NCT03356067 |
Recruiting |
Endoscopic Pyloromyotomy for Refractory Gastroparesis |
|
- Procedure: Gastric endoscopic peroral pyloromyotomy
- Procedure: Esophago-gastro-duodenoscopy
|
Interventional |
Not Applicable |
- Institute for Clinical and Experimental Medicine
- Universitätsklinikum Hamburg-Eppendorf
- Katholieke Universiteit Leuven
- (and 12 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Main outcome is the proportion of patients with treatment success after the procedure.
- Proportion of patients with treatment success in the active arm after 3 months
- Proportion of patients with treatment success in the active arm after 12 months
- (and 13 more...)
|
86 |
All |
18 Years and older (Adult, Senior) |
NCT03356067 |
IClinicalEM2 |
GREG |
December 1, 2017 |
June 1, 2021 |
November 1, 2024 |
November 29, 2017 |
April 2, 2018 |
|
- University of Chicago
Chicago, Illinois, United States - Department of Hepatogastroenterology at Cliniques universitaires St-Luc, Brussels, Belgium
Brussels, Belgium - Translational Research in GastroIntestinal Disorders, Leuven, Belgium
Leuven, Belgium - (and 11 more...)
|
| 4 |
NCT00568373 |
Recruiting |
Gastric Pacemaker Implantation for Gastroparesis |
|
- Device: Enterra Gastric Pacemaker
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Decreased nausea and vomiting.
|
200 |
All |
Child, Adult, Senior |
NCT00568373 |
0705-32 |
HUD |
June 2007 |
December 2020 |
December 2020 |
December 6, 2007 |
March 30, 2018 |
|
- Indiana University
Indianapolis, Indiana, United States - Riley Hospital for Children
Indianapolis, Indiana, United States
|
| 5 |
NCT02164591 |
Recruiting |
Escalating Temporary Gastric Electrical Stimulation (GES) for Severe Gastroparesis |
|
|
Observational |
|
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Improvement in the symptoms of gastroparesis by t-GES in patients with severe gastroparesis.
- Clinical response to t-GES placement as measured by questionnaires
- Develop a prospective registry in patients undergoing escalating t-GES
- determine the feasibility and patient tolerability of endoscopic placement of t-GES
|
200 |
All |
18 Years to 90 Years (Adult, Senior) |
NCT02164591 |
Temp GES |
TempGES |
February 2013 |
December 2020 |
December 2020 |
June 16, 2014 |
October 13, 2017 |
|
- Indiana University Hosptial
Indianapolis, Indiana, United States
|
| 6 |
NCT02970968 |
Recruiting |
Study to Assess the Efficacy of VLY-686 in Relieving Symptoms of Gastroparesis |
|
- Drug: VLY-686 (Tradipitant)
- Other: Placebo
|
Interventional |
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Change in gastroparesis associated symptoms as assessed by patient reported diary
|
150 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT02970968 |
VP-VLY-686-2301 |
|
November 2016 |
October 2017 |
November 2017 |
November 22, 2016 |
August 23, 2017 |
|
- Vanda Investigational Site
Dothan, Alabama, United States - Vanda Investigational Site
Huntsville, Alabama, United States - Vanda Investigational Site
Tucson, Arizona, United States - (and 25 more...)
|
| 7 |
NCT01625923 |
Recruiting |
A Pilot Study on the Efficacy and Safety of Olanzapine in Gastroparesis |
|
|
Interventional |
Not Applicable |
- University of Michigan
- Massachusetts General Hospital
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Number of subjects with adverse events
- Number of subjects with symptomatic improvement
- Number of subjects with improved gastric motility
- Number of subjects with altered ghrelin levels
|
20 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT01625923 |
ACG-SP-002-2012 |
|
January 2013 |
December 2018 |
December 2018 |
June 22, 2012 |
July 2, 2017 |
|
- Massachusetts General Hospital
Boston, Massachusetts, United States - University of Michigan
Ann Arbor, Michigan, United States
|
| 8 |
NCT02927886 |
Not yet recruiting |
Per-oral Endoscopy Pyloromyotomy (G-POEM) in the Treatment of Refractory Diabetic Gastroparesis : Prospective Evaluation of Efficacy |
|
- Procedure: Per-oral endoscopy pyloromyotomy
- Procedure: Intrapyloric injection of Botulinum toxin
|
Interventional |
Phase 3 |
- Assistance Publique Hopitaux De Marseille
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Gastroparesis Cardinal Symptom Index score calculation
|
40 |
All |
18 Years and older (Adult, Senior) |
NCT02927886 |
2016-17
2016-A01365-46 |
G-POEM |
November 2016 |
September 2019 |
March 2020 |
October 7, 2016 |
October 18, 2016 |
|
- Gastro-entérologie, Hôpital Nord ,Assistance Publique Hôpitaux de Marseille
Marseille, France
|
| 9 |
NCT03342157 |
Recruiting |
Docusate/Senna for the Treatment of Diabetic Gastroparesis |
|
|
Interventional |
Phase 2 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Modified Gastroparesis Cardinal Symptom Index-Daily Diary (mGCSI-DD)
- Frequency of use of breakthrough medication
- Frequency of bowel movements
|
60 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT03342157 |
17.120 |
|
April 2, 2018 |
January 25, 2019 |
January 25, 2019 |
November 14, 2017 |
April 4, 2018 |
|
- Aurora Health Care
Milwaukee, Wisconsin, United States
|
| 10 |
NCT03123809 |
Recruiting |
Gastric Electrical Stimulation (GES) and Pyloroplasty for the Treatment of Gastroparesis |
- Diabetic and Idiopathic Gastroparesis
|
- Device: Gastric Electrical Stimulation (GES) system
|
Interventional |
Not Applicable |
- Texas Tech University Health Sciences Center, El Paso
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Changes of total gastroparesis symptom scores (TSS)
- Percentage of changes of gastric emptying retention of the radiolabeled meal (%) at 2-4 hrs
- Total Symptom Score (TSS) with severity and frequency of gastroparesis symptoms in each etiological subgroup of patients
- Associations between changes in gastric emptying and TSS
|
50 |
All |
18 Years to 65 Years (Adult) |
NCT03123809 |
E16156 |
GES+PP |
January 10, 2017 |
May 15, 2020 |
December 15, 2020 |
April 21, 2017 |
April 21, 2017 |
|
- Texas Tech University Health Sciences Center
El Paso, Texas, United States
|
| 11 |
NCT03036891 |
Not yet recruiting |
Naloxegol for Opioid-Related Gastroparesis |
|
- Drug: Naloxegol 25 MG Oral Tablet [Movantik]
- Drug: Placebo Oral Tablet
|
Interventional |
Phase 2 |
- Temple University
- AstraZeneca
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Gastric Emptying (GE t-1/2)
- Daily Symptom Improvement using the GCSI-DD (Gastroparesis Cardinal Symptom Index-Daily Diary)
- Symptom Improvement using PAGI-SYM
- (and 3 more...)
|
24 |
All |
18 Years to 84 Years (Adult, Senior) |
NCT03036891 |
24102 |
|
March 1, 2017 |
March 1, 2019 |
March 1, 2020 |
January 30, 2017 |
January 31, 2017 |
|
|
| 12 |
NCT03281577 |
Recruiting |
Effect of TAK-954 on Gastrointestinal and Colonic Transit in Diabetic or Idiopathic Gastroparesis Participants |
- Diabetic Gastroparesis
- Idiopathic Gastroparesis
|
- Drug: TAK-954
- Drug: Placebo
|
Interventional |
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Half time (T1/2) of Gastric Emptying of Solids
- Colonic Geometric Center at 4, 24, and 48 Hours
- Colonic Filling at 6 Hours (Measure of Small Bowel Transit Time)
- (and 9 more...)
|
48 |
All |
18 Years to 65 Years (Adult) |
NCT03281577 |
TAK-954-2003 |
|
January 2, 2018 |
December 21, 2018 |
December 21, 2018 |
September 13, 2017 |
January 9, 2018 |
|
- Mayo Clinic
Rochester, Minnesota, United States
|
| 13 |
NCT01557296 |
Recruiting |
Evaluation of Diagnostic Methods and Dietary Treatment of Diabetic Gastroparesis |
|
- Dietary Supplement: dietary treatment: food of small particle size
- Radiation: Validate X-ray diagnostic method.
- Other: Can the motility be improved
- Biological: postprandial plasma glucose
|
Interventional |
Phase 2 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Metabolic Control - HbA1c
- gastrointestinal symptoms - Questionnaire: Patient Assessment of upper Gastrointestinal Disorders Symptoms, Gastrointestinal Symptom Rating Scale
|
50 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT01557296 |
#EMS-5115# |
|
September 2007 |
May 2018 |
May 2018 |
March 19, 2012 |
February 21, 2018 |
|
- Goteborg Universitet, Sahlgrenska Academy, Sahlgrenska University Hospital
Goteborg, Sweden
|
| 14 |
NCT02732821 |
Recruiting |
G-POEM for Treatment of Refractory Gastroparesis |
- Diabetic Gastroparesis
- Idiopathic Gastroparesis
- Gastroparesis Postoperative
|
- Procedure: Gastric Per Oral Endoscopic Myotomy
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Efficacy of the G-POEM
- Patient symptom improvement
- Delayed gastric emptying using a Gastric emptying study
- Quality of life
|
80 |
All |
18 Years to 100 Years (Adult, Senior) |
NCT02732821 |
IRB00066924 |
|
May 2015 |
December 2018 |
December 2018 |
April 11, 2016 |
January 5, 2018 |
|
- Johns Hopkins Hospital
Baltimore, Maryland, United States
|
| 15 |
NCT02494687 |
Available |
Domperidone Expanded Access Program for Oncology Patients With Gastroparesis Who Have Failed Standard Therapy |
- Oncology Patients With Gastroparesis
|
|
Expanded Access |
|
- Eastern Regional Medical Center
|
Other |
|
|
|
All |
18 Years and older (Adult, Senior) |
NCT02494687 |
EP2014022 |
|
|
|
|
July 10, 2015 |
July 6, 2017 |
|
- Eastern Regional Medical Center, Inc.
Philadelphia, Pennsylvania, United States
|
| 16 |
NCT03120325 |
Recruiting |
Vagal Nerve Stimulation for Gastroparesis |
|
- Device: Vagal Nerve Stimulation
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Effect of Vagal Nerve Stimulation on gastroparesis symptoms as measures by the Gastroparesis Cardinal Symptom Index (GCSI) questionnaire.
- Effect of Vagal Nerve Stimulation on the gastric emptying spirulina breath test emptying time
|
45 |
All |
21 Years to 65 Years (Adult) |
NCT03120325 |
39839 |
VNS |
March 1, 2017 |
March 1, 2018 |
July 1, 2018 |
April 19, 2017 |
February 8, 2018 |
|
- Stanford University Medical Center
Palo Alto, California, United States
|
| 17 |
NCT03285308 |
Recruiting |
A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis |
- Gastroparesis
- Diabetes Mellitus
|
- Drug: Relamorelin
- Drug: Placebo
|
Interventional |
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Percentage of patients meeting the diabetic gastroparesis symptom responder criterion in each of the last 6 of the 12 weeks of treatment
- Percentage of patients meeting the vomiting symptom responder criterion in each of the last 6 of the 12 weeks of treatment
- Percentage of Patients Meeting the Nausea Responder Criterion
- (and 4 more...)
|
600 |
All |
18 Years and older (Adult, Senior) |
NCT03285308 |
RLM-MD-01
2017-002136-16 |
|
September 29, 2017 |
July 5, 2020 |
July 5, 2020 |
September 18, 2017 |
March 27, 2018 |
|
- Digestive Health Specialist of the South East
Dothan, Alabama, United States - Del Sol Research Management, LLC
Chandler, Arizona, United States - Phoenix Clinical LLC.
Phoenix, Arizona, United States - (and 175 more...)
|
| 18 |
NCT03426345 |
Recruiting |
Study to Evaluate the Safety and Efficacy of Relamorelin in Patients With Diabetic Gastroparesis Study 02 |
- Gastroparesis
- Diabetes Mellitus
|
- Drug: Relamorelin
- Drug: Placebo
|
Interventional |
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Percentage of patients meeting the diabetic gastroparesis symptom responder criterion in each of the last 6 of the 12 weeks of treatment
- Percentage of patients meeting the vomiting symptom responder criterion in each of the last 6 of the 12 weeks of treatment
- Percentage of Patients Meeting the Nausea Responder Criterion
- (and 4 more...)
|
600 |
All |
18 Years and older (Adult, Senior) |
NCT03426345 |
RLM-MD-02
2017-002177-20 |
|
February 16, 2018 |
June 8, 2021 |
June 8, 2021 |
February 8, 2018 |
March 16, 2018 |
|
- North Alabama Research Center, LLC
Athens, Alabama, United States - Alabama Medical Group, PC
Mobile, Alabama, United States - Preferred Research Partners, Inc.
Little Rock, Arkansas, United States - (and 34 more...)
|
| 19 |
NCT02031081 |
Recruiting |
Prucalopride Versus Placebo in Gastroparesis |
- Gastroparesis
- Diabetes Mellitus
|
- Drug: Prucalopride
- Drug: Placebo
|
Interventional |
Phase 2
Phase 3 |
- University of Calgary
- Janssen Inc.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change In Cumulative Meal-related Symptoms
- Gastric Emptying Rate
|
30 |
All |
18 Years to 64 Years (Adult) |
NCT02031081 |
PruGP |
|
March 2014 |
June 2018 |
December 2018 |
January 9, 2014 |
November 17, 2017 |
|
- University of Calgary
Calgary, Alberta, Canada
|
| 20 |
NCT03126513 |
Recruiting |
Gastric Per Oral Endoscopic Myotomy (G-POEM) in Refractory Gastroparesis |
- Gastroparesis Postoperative
- Gastroparesis Due to Diabetes Mellitus
- Idiopathic Gastric Stasis
|
|
Interventional |
Not Applicable |
- Coordinación de Investigación en Salud, Mexico
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Efficacy of G-POEM in gastroparesis in percentage of scintigraphic improvement at 4hrs
- Efficacy of G-POEM in gastroparesis in percentage of improvement in GCSI questionnaire of symptoms
- security of G-POEM in gastroparesis
|
50 |
All |
18 Years to 90 Years (Adult, Senior) |
NCT03126513 |
R-2017-3601-45 |
G-POEM |
April 1, 2017 |
May 1, 2018 |
October 1, 2018 |
April 24, 2017 |
April 24, 2017 |
|
- Centro Medico Nacional Siglo XXI Hospital de Especialidades
Mexico, Mexico city, Mexico
|
| 21 |
NCT02452489 |
Recruiting |
Different Acupoints Compatibility Difference of the Effect of Treatment of the Diabetic Gastroparesis |
|
|
Interventional |
Phase 1 |
- Changchun University of Chinese Medicine
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
- Hengyang Traditional Chinese Medicine Hospital
- (and 3 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Gastroparesis Symptoms Rating Scale(GCSI)
- FBG(fasting blood-glucose)
- PPG(postprandial blood sugar)
- (and 5 more...)
|
99 |
All |
18 Years to 65 Years (Adult) |
NCT02452489 |
ChangchunUCM02 |
|
January 2015 |
December 2017 |
August 2018 |
May 22, 2015 |
May 22, 2015 |
|
- The Affiliated Hospital To Changchun University of Chinese Medicine
Changchun, Jilin, China
|
| 22 |
NCT02227927 |
Available |
Treatment Use of Domperidone for Gastroparesis |
- Gastroesophageal Reflux Disease
- GERD
- Gastroparesis
|
|
Expanded Access |
|
|
Other |
|
|
|
All |
18 Years and older (Adult, Senior) |
NCT02227927 |
CCF-Domperidone |
|
|
|
|
August 28, 2014 |
November 21, 2017 |
|
- Cleveland Clinic
Cleveland, Ohio, United States
|
| 23 |
NCT02838797 |
Recruiting |
RQ-00000010 for Gastroparesis and Constipation in Parkinson's Disease |
- Parkinson's Disease
- Gastroparesis
- Constipation
|
- Drug: RQ-00000010
- Drug: Placebo
|
Interventional |
Phase 1 |
- Virginia Commonwealth University
- Michael J. Fox Foundation for Parkinson's Research
- RaQualia Pharma Inc.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Number of Participants With Abnormal Laboratory Values and/or Adverse Events That Are Related to Treatment
- Gastric emptying
- Area Under the Curve [AUC] for RQ-00000010 after single and multiple doses
- Peak Plasma Concentration (Cmax) for RQ-00000010 after single and multiple doses
|
75 |
All |
18 Years and older (Adult, Senior) |
NCT02838797 |
HM20001657 |
RQ-10 |
June 2016 |
March 2019 |
March 2019 |
July 20, 2016 |
April 3, 2018 |
|
- VCU NOW Center
Henrico, Virginia, United States
|
| 24 |
NCT02635399 |
Recruiting |
Impact of Additional DJ (Duodenojejunostomy)-Pexy on Reduction in Delayed Gastric Emptying Following Pylorus-preserving Pancreaticoduodenectomy: A Prospective, Randomized Controlled Trial |
|
- Procedure: PPPD (pylorus-preserving pancreaticoduodenectomy)
- Procedure: PPPD (pylorus-preserving pancreaticoduodenectomy) with DJ-pexy
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Occurence of clinically relevant DGE
- Risk factors influencing DGE
|
78 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT02635399 |
4-2015-0969 |
|
January 2016 |
December 2017 |
December 2017 |
December 18, 2015 |
November 15, 2016 |
|
- Severance Hospital
Seoul, Korea, Republic of
|
| 25 |
NCT03376399 |
Recruiting |
Potential Benefits of Sleeve Gastrectomy Surgery on Diabetic Gastroparesis Symptoms |
- Weight Loss
- Diabetic Gastroparesis
- Bariatric Surgery Candidate
- (and 2 more...)
|
- Other: Gastroparesis Cardinal Symptom Index Questionnaire
|
Observational |
|
- Baylor Research Institute
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Examine gastroparesis symptoms
|
30 |
All |
18 Years and older (Adult, Senior) |
NCT03376399 |
IRB 017-370 |
|
October 25, 2017 |
December 31, 2019 |
December 31, 2019 |
December 18, 2017 |
December 26, 2017 |
|
- Baylor Weight Loss Surgery Center
Dallas, Texas, United States
|
| 26 |
NCT03438305 |
Not yet recruiting |
Role of Gastric Ultrasound in Preoperative Assessment of Gastric Volume in Diabetic Patients. |
|
- Other: sonar assessment of gastric volume in Diabetic patients
- Other: sonar assessment of gastric volume in Non Diabetic patients
|
Observational |
|
|
Other |
- Observational Model: Other
- Time Perspective: Prospective
|
- assessment of residual gastric volume in longstanding diabetic patients
- correlation between preoperative gastric US findings and fasting hours in both groups
|
48 |
All |
40 Years to 60 Years (Adult) |
NCT03438305 |
N-74-2017 |
|
March 1, 2018 |
June 1, 2018 |
June 1, 2018 |
February 19, 2018 |
February 19, 2018 |
|
|
| 27 |
NCT03259841 |
Not yet recruiting |
Ultrasound Assessment of Gastric Contents in Fasted Patient Undergoing Cholecystectomy |
|
- Other: Ultrasound assessment of gastric contet
|
Observational |
|
- SMG-SNU Boramae Medical Center
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Incidence of full stomach
- Cross sectional area of the stomach
- Volume of stomach
- Type of gastric contents
|
240 |
All |
20 Years and older (Adult, Senior) |
NCT03259841 |
2017-8-4 |
|
September 14, 2017 |
September 14, 2018 |
October 14, 2019 |
August 24, 2017 |
August 24, 2017 |
|
- Seoul Metropolitan Government Seoul National University Boramae Medical Center
Seoul, Korea, Republic of
|
| 28 |
NCT02165059 |
Recruiting |
GI Neuromuscular Pathology Prospective Registry |
|
|
Observational |
|
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- Clinical data at 4 time periods for study patents will be measured
- Positive Clinical Outcome to surgical implantation of GES measured by GCSI
- Neuromuscular pathology results of the gastric body and proximal jejunum wil be compared between the following groups
- Correlation of Pathology Results and Questionnaire
|
200 |
All |
6 Months to 90 Years (Child, Adult, Senior) |
NCT02165059 |
GI Neuromuscular Pathology |
|
December 2013 |
December 2020 |
December 2020 |
June 17, 2014 |
October 13, 2017 |
|
- Indiana University Hosptial
Indianapolis, Indiana, United States
|
| 29 |
NCT00777439 |
Recruiting |
Domperidone for Refractory Gastrointestinal Disorders |
|
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Improvement of symptoms for patients with gastrointestinal disorders who have failed or suffered adverse effects from standard medical treatment.
|
75 |
All |
18 Years and older (Adult, Senior) |
NCT00777439 |
GLA102024 |
|
October 2008 |
January 2017 |
January 2018 |
October 22, 2008 |
August 18, 2016 |
|
- Division of Gastroenterology, Hepatology and Nutrition, UPMC Presbyterian Digesive Disorders Center, 3rd Floor, 200 Lothrop Street
Pittsburgh, Pennsylvania, United States
|
| 30 |
NCT03294616 |
Recruiting |
Transcutaneous Electroacupuncture for Gastric Complications of Scleroderma |
|
- Device: transcutaneous electroacupuncture
|
Interventional |
Not Applicable |
- Johns Hopkins University
- Transtimulation Research, Inc
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Crossover Assignment
- Masking: Triple (Participant, Care Provider, Outcomes Assessor)
- Primary Purpose: Treatment
|
- effect of TEA on symptoms in Systemic Sclerosis (SSc) patients
- effects of TEA on gastric motility
- effects of TEA on autonomic function
- effects of TEA on GI hormones and inflammatory cytokine
|
20 |
All |
18 Years and older (Adult, Senior) |
NCT03294616 |
IRB00089514 |
|
February 6, 2017 |
August 31, 2018 |
November 1, 2018 |
September 27, 2017 |
November 6, 2017 |
|
- Johns Hopkins Bayview Medical Center
Baltimore, Maryland, United States
|
| 31 |
NCT02567175 |
Available |
Domperidone Expanded Access Protocol for Patients With Gastrointestinal Disorders |
- Refractory Gastroesophageal Reflux Disease With Upper Gastrointestinal (GI) Symptoms, Gastroparesis, and Chronic Constipation
|
|
Expanded Access |
|
- Kristin Fiorino
- Children's Hospital of Philadelphia
|
Other |
|
|
|
All |
12 Years and older (Child, Adult, Senior) |
NCT02567175 |
14-010908 |
|
|
|
|
October 2, 2015 |
November 6, 2017 |
|
- The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
|
| 32 |
NCT02954302 |
Recruiting |
Proximal Roux-en-y Gastrojejunal Anastomosis on Delayed Gastric Emptying After Pylorus-resecting Pancreaticoduodenectomy |
- Pancreatic Cancer
- Bile Duct Cancer
- Duodenal Cancer
|
- Procedure: PrPD with proximal Roux-en-y gastrojejunal anastomosis
- Procedure: conventional PrPD
|
Interventional |
Not Applicable |
- The First Affiliated Hospital of Xiamen University
- LanZhou University
- Eastern Hepatobiliary Surgery Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Delayed gastric emptying,rate
- Morbidity,rate
- Mortality,rate
- (and 6 more...)
|
140 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02954302 |
FAHXMU-2016-04 |
|
September 2016 |
November 2018 |
December 2018 |
November 3, 2016 |
November 3, 2016 |
|
- First affiliated Hospital of Xiamen University
Xiamen, Fujian, China
|
| 33 |
NCT03011151 |
Recruiting |
Protease Activated Receptor-2 and Gastrointestinal Dysfunction in Critical Illness |
- Gastroparesis
- Gastrointestinal Disorder, Functional
- Critical Illness
|
|
Observational |
|
- Boston Children’s Hospital
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- PAR2 agonist activity- serum zonulin
- PAR2 agonist activity- fecal protease activity
- Gastric motility by the acetaminophen absorption test- AUC
- (and 3 more...)
|
80 |
All |
2 Years to 30 Years (Child, Adult) |
NCT03011151 |
IRB-P00024070 |
|
June 19, 2017 |
December 2018 |
December 2018 |
January 5, 2017 |
June 20, 2017 |
|
- Boston Children's Hospital
Boston, Massachusetts, United States
|
| 34 |
NCT03089632 |
Recruiting |
The Effect of Gluten-free Diet in Type 1 Diabetics With Dyspepsia Symptoms |
- Diabetes Mellitus, Type 1
- Gastroparesis
- Dyspepsia
- Gluten Sensitivity
|
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Changes in upper gastrointestinal symptoms assessed by the Leeds short-form questionnaire (SF-LDQ)
- Changes in upper gastrointestinal symptoms assessed by the Gastroparesis Cardinal Symptoms Index (GCSI)
- Changes in gastric emptying determined by gastric scintigraphy.
- (and 2 more...)
|
30 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT03089632 |
DM1 and GFD_01 |
|
December 15, 2017 |
June 1, 2018 |
June 30, 2018 |
March 24, 2017 |
December 20, 2017 |
|
- McMaster Health Sciences Centre
Hamilton, Ontario, Canada
|
| 35 |
NCT03150615 |
Recruiting |
Enteral Nutrition After Pancreaticoduodenectomy |
- Cancer of Pancreas
- Cancer of Duodenum
- Ampulla of Vater Cancer
- Cholangiocarcinoma
|
- Other: Early enteral nutrition
- Other: Saline
- Device: nasojejunal tube insertion
- Other: Oral intake
|
Interventional |
Not Applicable |
- Nanjing Medical University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Incident rate of delayed gastric emptying
- Postoperative hospital stay length
- Overall morbidity rate
- (and 7 more...)
|
120 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT03150615 |
NMU-JSPH-PC-Nutrition |
|
September 2016 |
December 2017 |
December 2017 |
May 12, 2017 |
August 1, 2017 |
|
- The first affiliated hospital of Nanjing Medical University
Nanjing, Jiangsu, China
|
| 36 |
NCT03242733 |
Not yet recruiting |
Ultrasound Assessment of Gastric Contents in Fasted Elderly Patients With Hip Fracture |
|
- Other: Ultrasound assessment of gastric contents
|
Observational |
|
- SMG-SNU Boramae Medical Center
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Ultrasound assessment of the presence of gastric contents.
- Ultrasound assessment of the component of residual gastric contents
|
200 |
All |
65 Years and older (Adult, Senior) |
NCT03242733 |
20170804/10/2017/8 |
|
September 2017 |
September 2019 |
September 2019 |
August 8, 2017 |
August 22, 2017 |
|
- Seoul Metropolitan Government Seoul National University Boramae Medical Center
Seoul, Korea, Republic of
|
| 37 |
NCT02694081 |
Recruiting |
The Advantages and Disadvantages Between Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction After Laparoscopy-assisted Distal Gastrectomy for Gastric |
|
- Procedure: Uncut Roux-en-Y Reconstruction
- Procedure: Billroth II Reconstruction
|
Interventional |
Phase 2 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- The time of reconstruction during operations of Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction
- change of potential of hydrogen ( pH) in remnant stomach
- the amount of blood loss during operations of Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction
- (and 2 more...)
|
100 |
All |
up to 85 Years (Child, Adult, Senior) |
NCT02694081 |
130021
714488468 |
|
February 2016 |
February 2017 |
February 2017 |
February 29, 2016 |
January 2, 2017 |
|
- the first hospital of Jilin University
Changchun, Jilin, China
|
| 38 |
NCT03310528 |
Recruiting |
Gastric Ultrasound for Estimation of the Aspiration Risk Study |
- Respiratory Aspiration of Gastric Contents
|
- Behavioral: Interview questionnaire
- Procedure: Gastric ultrasound exam
|
Observational |
|
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- Changes in gastric content volume between the four groups assessed by ultrasound examination
|
200 |
All |
18 Years to 99 Years (Adult, Senior) |
NCT03310528 |
IRB201602234 |
|
March 27, 2018 |
October 2019 |
December 2019 |
October 16, 2017 |
April 11, 2018 |
|
- United States, Florida UF Health
Gainesville, Florida, United States
|
| 39 |
NCT03396796 |
Not yet recruiting |
Vagus Nerve-preserving Laparoscopic Splenectomy and Azygoportal Disconnection |
- Cirrhosis
- Hypertension
- Splenectomy
- Laparoscopy
|
- Procedure: Vagus nerve-preserving group
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Delayed gastric emptying
- Postoperative complications of the digestive system
- Body weight
- (and 4 more...)
|
60 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT03396796 |
YZUC-003 |
ESVLSD |
January 10, 2018 |
October 31, 2019 |
October 31, 2019 |
January 11, 2018 |
January 11, 2018 |
|
- Clinical Medical College of Yangzhou University
Yangzhou, Jiangsu, China
|
| 40 |
NCT01696734 |
Recruiting |
Treatment Protocol for the Compassionate Use of Domperidone |
- Gastrointestinal Diseases
|
- Drug: Domperidone
- Behavioral: Questionnaires
- Other: Phone Calls
|
Interventional |
Phase 3 |
- M.D. Anderson Cancer Center
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Symptom Control of Chronic Gastrointestinal Disorders
|
200 |
All |
16 Years and older (Child, Adult, Senior) |
NCT01696734 |
2012-0261
NCI-2012-02093 |
|
October 2012 |
October 2019 |
October 2019 |
October 1, 2012 |
October 31, 2017 |
|
- University of Texas MD Anderson Cancer Center
Houston, Texas, United States
|
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