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57 studies found for:    Open Studies | "Gastrointestinal Stromal Tumors"

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Open Studies | "Gastrointestinal Stromal Tumors" (57 records)
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Rank Status Study
1 Recruiting Efficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)
Conditions: Gastrointestinal Stromal Tumors;   KIT +;   Resected Gastrointestinal Stromal Tumors;   Non-metastatic;   High Risk of Recurrence
Intervention: Drug: Imatinib maintenance
2 Recruiting Study of Tumor Samples in Patients Undergoing Treatment for Gastrointestinal Stromal Tumors on Clinical Trial ACOSOG-Z9001
Condition: Gastrointestinal Stromal Tumor
Interventions: Genetic: mutation analysis;   Genetic: polymorphism analysis;   Other: laboratory biomarker analysis
3 Unknown † A Phase 3 Study to Evaluate Efficacy and Safety of Masitinib in Comparison to Sunitinib in Patients With Gastrointestinal Stromal Tumour After Progression With Imatinib
Condition: Gastrointestinal Stromal Tumors
Interventions: Drug: Masitinib;   Drug: Sunitinib
4 Unknown † A Phase 3 Study to Evaluate Efficacy and Safety of Masitinib in Comparison to Imatinib in Patients With Gastro-Intestinal Stromal Tumour in First Line Medical Treatment
Condition: Gastrointestinal Stromal Tumors
Interventions: Drug: masitinib (AB1010);   Drug: imatinib
5 Recruiting Efficacy and Safety of PD-0332991 in Patients With Advanced Gastrointestinal Stromal Tumors Refractory to Imatinib and Sunitinib
Condition: Advanced Gastrointestinal Stromal Tumors
Intervention: Drug: PD-0332991 will be administrated orally, formulated as gelatin capsules of 100 mg and 25 mg respectively.
6 Recruiting A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal Tumor
Condition: Gastrointestinal Stromal Tumors
Interventions: Drug: sunitinib malate dose escalation;   Drug: sunitinib malate
7 Not yet recruiting A Study of BBI503 in Adult Patients With Advanced Gastrointestinal Stromal Tumors
Condition: Gastrointestinal Stromal Tumors
Intervention: Drug: BBI503
8 Unknown † Gleevec Administered Preoperatively to Reduce Gastrointestinal Stromal Tumor (GIST)
Condition: Gastrointestinal Stromal Tumors
Intervention: Drug: Imatinib mesylate
9 Not yet recruiting the Laparoscopic and Endoscopic Cooperative Surgery of Gastrointestinal Stromal Tumor
Condition: Gastrointestinal Stromal Tumor
Interventions: Procedure: Laparoscopic endoscopy combined surgery;   Procedure: laparoscopic and endoscopic cooperative surgery;   Procedure: Single-arch laparoscopic and endoscopic cooperative surgery
10 Unknown † A Retrospective Clinical Records Review of Patients Diagnosed With Gastrointestinal Stromal Tumour at Two Tertiary Institutes in Singapore
Condition: Gastrointestinal Stromal Tumors
Intervention:
11 Not yet recruiting Nivolumab With or Without Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumor That Is Metastatic or Cannot Be Removed by Surgery
Condition: Gastrointestinal Stromal Tumor
Interventions: Biological: Ipilimumab;   Other: Laboratory Biomarker Analysis;   Biological: Nivolumab
12 Not yet recruiting Efficacy of Imatinib in Patients With Intermediate-risk Gastrointestinal Stromal Tumor With a High-risk Genomic Grade Index
Condition: Gastrointestinal Stromal Tumor
Interventions: Drug: Imatinib;   Other: Surveillance
13 Recruiting MEK162 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)
Condition: Gastrointestinal Stromal Tumor (GIST)
Interventions: Drug: MEK162;   Drug: Imatinib Mesylate (Gleevec®; STI571; NSC #716051);   Other: Blood draws;   Procedure: biopsy
14 Recruiting Phase 1 Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors
Conditions: Gastrointestinal Stromal Tumors (GIST);   Other Relapsed or Refractory Solid Tumors
Intervention: Drug: BLU-285
15 Recruiting A Randomised Trial of Imatinib Alternating With Regorafenib Compared to Imatinib Alone for the First Line Treatment of Advanced Gastrointestinal Stromal Tumour (GIST)
Condition: Gastrointestinal Stromal Tumour
Interventions: Drug: Regorafenib;   Drug: imatinib
16 Not yet recruiting A Study to Evaluate the Safety of Intuvax Administered Intra-tumorally in Patients With Gastrointestinal Stromal Tumors
Condition: Gastrointestinal Stromal Tumor
Intervention: Biological: Intuvax (suspension for intratumoral injection)
17 Recruiting Circulating Cell-free Tumor DNA in the Plasma of Patients With Gastrointestinal Stromal Tumors (GIST)
Condition: Gastrointestinal Stromal Tumor (GIST)
Intervention: Other: Vena puncture for blood collection
18 Not yet recruiting SARC029: Trametinib and Pazopanib in Patients With GIST (Gastrointestinal Stromal Tumor)
Condition: Gastrointestinal Stromal Tumors
Interventions: Drug: Pazopanib;   Drug: Trametinib
19 Recruiting BGJ398 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)
Condition: Advanced Gastrointestinal Stromal Tumor (GIST)
Interventions: Drug: BGJ398;   Drug: Imatinib Mesylate
20 Recruiting A Study of AUY922 for GIST(Gastrointestinal Stromal Tumor) Patients
Condition: Gastrointestinal Stromal Tumor
Intervention: Drug: AUY922
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† Indicates status has not been verified in more than two years