221 studies found for:    Open Studies | "Drug Interactions"
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Rank Status Study
1 Unknown  Study for Early Detection of Drug Interactions in Older Hospitalized Patients Using on Line Software
Condition: Drug Interactions
Intervention: Other: on line software to detect DI  early on
2 Recruiting A Drug-Drug Interaction Study of N91115 +/- Rifampin in Healthy Adult Subjects
Condition: Drug Interaction Potentiation
Interventions: Drug: N91115;   Drug: Rifampin
3 Unknown  Interaction Between Drug and Placebo Effect:Randomized Placebo Controlled Trials May Not be Accurate in Determining Drug Effect Size
Conditions: Placebo Effect;   Placebo Drug Interaction
Interventions: Drug: Hydroxizine;   Other: Placebo;   Drug: hydroxyzine/placebo
4 Not yet recruiting Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery
Conditions: Drug Interactions;   Anesthesia, Conduction
Interventions: Drug: Propofol and Remifentanil;   Drug: Sevoflurane and Remifentanil;   Drug: SPR 1;   Drug: SPR2
5 Recruiting Walking the Isobole of Drug Interaction
Conditions: Hemodynamic Instability;   Disorder of Oxygen Transport;   Interaction;   Anesthesia
Interventions: Drug: Group A propofol + remifentanil;   Drug: Group B propofol + remifentanil;   Drug: Group C propofol + remifentanil;   Drug: group D propofol + remifentanil
6 Recruiting A Drug-drug Interaction Study of AZD3293 in Healthy Volunteers
Condition: Drug-drug Interactions
Interventions: Drug: AZD3293;   Drug: Simvastatin;   Drug: Midazolam;   Drug: Donepezil
7 Recruiting YouScript IMPACT Registry
Conditions: Adverse Drug Events;   Adverse Drug Reactions;   Drug Interaction Potentiation;   Drug Metabolism, Poor, CYP2D6-RELATED;   Drug Metabolism, Poor, CYP2C19-RELATED;   Cytochrome P450 Enzyme Deficiency;   Cytochrome P450 CYP2D6 Enzyme Deficiency;   Cytochrome P450 CYP2C9 Enzyme Deficiency;   Cytochrome P450 CYP2C19 Enzyme Deficiency;   Cytochrome P450 CYP3A Enzyme Deficiency;   Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant;   Poor Metabolizer Due to Cytochrome P450 CYP2C19 Variant;   Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Intervention:
8 Unknown  Sorafenib Combined With Transarterial Chemoembolization in Treating HBV-infected Patients With Intermediate Hepatocellular Carcinoma
Conditions: PHENYTOIN/SORAFENIB [VA Drug Interaction];   Liver Neoplasms;   Carcinoma, Hepatocellular;   Digestive System Neoplasms;   Neoplasms by Site;   Liver Diseases;   Adenocarcinoma;   Carcinoma;   Neoplasms, Glandular and Epithelial;   Neoplasms by Histologic Type;   DOXORUBICIN/TRASTUZUMAB [VA Drug Interaction];   HBV
Interventions: Procedure: Transarterial Chemoembolization (TACE);   Other: Sorafenib in combination with TACE
9 Unknown  Effect of an Automated Paging System on Response to Critical Laboratory Values
Conditions: Critical Laboratory Values;   Drug Laboratory Interactions;   Drug Drug Interactions
Intervention: Procedure: Real Time Clinical Alerting
10 Recruiting Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Acute Myocardial Infarction
Conditions: ST-segment Elevation Myocardial Infarction;   Non-ST-segment Elevation Myocardial Infarction;   VA Drug Interactions [VA Drug Interaction]
Interventions: Drug: Morphine;   Drug: Placebo;   Drug: Ticagrelor
11 Not yet recruiting Pharmacokinetics and Pharmacodynamics of the Etonogestrel Contraceptive Implant When Co-administered With Efavirenz
Condition: Drug Interaction
Intervention: Drug: Efavirenz
12 Recruiting The Drug-drug Interaction of SHR3824 and SP2086
Condition: Type 2 Diabetes
Intervention: Drug: SHR3824, SP2086
13 Unknown  An Assessment of Milk Thistle Pharmacokinetics and Drug Interactions
Condition: Healthy
Intervention:
14 Recruiting Pharmacogenetic Testing Among Home Health Patients
Conditions: Adverse Drug Events;   Adverse Drug Reactions;   Drug Interaction Potentiation;   Drug Metabolism, Poor, CYP2D6-RELATED;   Drug Metabolism, Poor, CYP2C19-RELATED;   Cytochrome P450 Enzyme Deficiency;   Cytochrome P450 CYP2D6 Enzyme Deficiency;   Cytochrome P450 CYP2C9 Enzyme Deficiency;   Cytochrome P450 CYP2C19 Enzyme Deficiency;   Cytochrome P450 CYP3A Enzyme Deficiency;   Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant;   Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant;   Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Intervention: Genetic: Pharmacogenetic testing
15 Unknown  Impact of Omeprazole and Fluvoxamine on Platelet Response to Clopidogrel
Condition: Drug Interaction of Clopidogrel
Interventions: Drug: omeprazole;   Drug: fluvoxamine;   Drug: placebo
16 Recruiting First-in-human: Single Ascending Dose, Food Effect, Drug-drug Interaction, Multiple Ascending Dose, Proof of Pharmacology
Condition: Healthy Volunteers
Interventions: Drug: ASP6282;   Drug: Itraconazole;   Drug: Pilocarpine;   Drug: Placebo
17 Not yet recruiting TACE Combinated With Sorafenib in Treating Patients With Unresectable Hepatocellular Carcinoma
Conditions: PHENYTOIN/SORAFENIB [VA Drug Interaction];   Carcinoma, Hepatocellular
Interventions: Procedure: TACE;   Drug: sorafenib combined with TACE
18 Recruiting Counseling on the Interaction of Hormonal Contraceptives and Antiepileptics
Condition: Epilepsy
Intervention: Other: Educational handout
19 Recruiting Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM
Conditions: Cytochrome P450 CYP2D6 Enzyme Deficiency;   Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant;   Ultrarapid Metabolizer Due to Cytochrome P450 CYP2D6 Variant;   Extensive Metabolizer Due to Cytochrome P450 CYP2D6 Variant;   Cytochrome P450 CYP2C9 Enzyme Deficiency;   Cytochrome P450 CYP2C19 Enzyme Deficiency;   Drug Metabolism, Poor, CYP2D6-RELATED;   Drug Metabolism, Poor, CYP2C19-RELATED;   CYP2D6 Polymorphism
Interventions: Genetic: Pharmacogenetic testing;   Other: Software-based drug & gene interaction risk analysis;   Other: MTM
20 Unknown  Herb Drug Interaction of Traditional Chinese Herb and Commonly Used Drugs
Condition: Healthy
Interventions: Drug: Nalbuphine;   Drug: Morphine;   Drug: Morphine with Long dan xie gan tang;   Drug: Nalbuphine with Long dan xie gan tang;   Drug: Nubian with Long dan xie gan tang

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Indicates status has not been verified in more than two years