52 studies found for:    Open Studies | "Down Syndrome"
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Open Studies | "Down Syndrome"
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Rank Status Study
1 Recruiting Down Syndrome Metabolic Health Study
Conditions: Down Syndrome;   Trisomy 21
Intervention:
2 Recruiting Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome
Conditions: Childhood Acute Myeloid Leukemia;   Childhood Myelodysplastic Syndrome;   Cytopenia;   Down Syndrome;   Myeloid Leukemia Associated With Down Syndrome;   Myeloproliferative Neoplasm
Interventions: Drug: Asparaginase;   Drug: Asparaginase Erwinia chrysanthemi;   Drug: Cytarabine;   Drug: Daunorubicin Hydrochloride;   Drug: Etoposide;   Other: Laboratory Biomarker Analysis;   Drug: Mitoxantrone Hydrochloride;   Drug: Thioguanine
3 Recruiting Nicotine Treatment of Cognitive Decline in Down Syndrome
Conditions: Down Syndrome;   Mild Cognitive Impairment
Interventions: Drug: Low Dose Nicotine (7mg);   Drug: Moderate Dose Nicotine (14mg)
4 Unknown  Down Syndrome and Continuous Positive Pressure Therapy
Conditions: Down Syndrome;   Obstructive Sleep Apnea Syndrome
Intervention: Device: Continuous Positive Pressure
5 Recruiting DS-Connect {TM}: The Down Syndrome Registry
Condition: Down Syndrome
Intervention:
6 Unknown  Memantine and Down's Syndrome
Conditions: Down's Syndrome;   Dementia;   Learning Disabilities
Intervention: Drug: Memantine Hydrochloride
7 Unknown  Trends in Intellectual Development in Down Syndrome
Condition: Down Syndrome
Intervention:
8 Recruiting Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
Conditions: Down Syndrome;   Subclinical Hypothyroidism
Intervention: Drug: Levothyroxine
9 Recruiting Phenotypic Specific Communication Intervention for Children With Down Syndrome
Conditions: Language Impairment;   Down Syndrome
Intervention: Behavioral: Jasper-EMT with words and AAC
10 Recruiting Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite
Condition: Down Syndrome
Intervention: Procedure: custom orthotics
11 Recruiting Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome
Conditions: Down Syndrome;   Obstructive Sleep Apnea
Intervention:
12 Recruiting Natural History of Amyloid Deposition in Adults With Down Syndrome
Condition: Down Syndrome
Intervention:
13 Recruiting Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children
Condition: Down Syndrome
Intervention: Drug: thyroid hormone and folinic acid
14 Recruiting A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living.
Condition: Down Syndrome
Interventions: Drug: E2020-Donepezil hydrochloride;   Drug: Placebo
15 Recruiting Non Invasive Prenatal Testing of Down Syndrome
Condition: Down Syndrome
Interventions: Procedure: Non Invasive Prenatal Testing;   Procedure: Invasive Prenatal Testing
16 Unknown  Trisomy 21 in Adulthood
Condition: Down Syndrome
Intervention: Genetic: karyotype
17 Recruiting Down Syndrome Memantine Follow-up Study
Conditions: Down Syndrome;   Intellectual Disability
Interventions: Drug: Memantine;   Drug: Placebo
18 Unknown  Neuromuscular Characteristics of Individuals With Down Syndrome (DS)
Condition: Down Syndrome
Intervention: Other: muscle strength
19 Unknown  Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down Syndrome
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:
20 Unknown  Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:

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