46 studies found for:    Open Studies | "Down Syndrome"
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Rank Status Study
1 Recruiting Down Syndrome Metabolic Health Study
Conditions: Down Syndrome;   Trisomy 21
Intervention:
2 Recruiting Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome
Conditions: Childhood Acute Myeloid Leukemia;   Childhood Myelodysplastic Syndrome;   Cytopenia;   Down Syndrome;   Myeloid Leukemia Associated With Down Syndrome;   Myeloproliferative Neoplasm
Interventions: Drug: Asparaginase;   Drug: Asparaginase Erwinia chrysanthemi;   Drug: Cytarabine;   Drug: Daunorubicin Hydrochloride;   Drug: Etoposide;   Other: Laboratory Biomarker Analysis;   Drug: Mitoxantrone Hydrochloride;   Drug: Thioguanine
3 Recruiting Nicotine Treatment of Cognitive Decline in Down Syndrome
Conditions: Down Syndrome;   Mild Cognitive Impairment
Interventions: Drug: Low Dose Nicotine (7mg);   Drug: Moderate Dose Nicotine (14mg)
4 Unknown  Down Syndrome and Continuous Positive Pressure Therapy
Conditions: Down Syndrome;   Obstructive Sleep Apnea Syndrome
Intervention: Device: Continuous Positive Pressure
5 Unknown  Memantine and Down's Syndrome
Conditions: Down's Syndrome;   Dementia;   Learning Disabilities
Intervention: Drug: Memantine Hydrochloride
6 Unknown  Trends in Intellectual Development in Down Syndrome
Condition: Down Syndrome
Intervention:
7 Recruiting Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
Conditions: Down Syndrome;   Subclinical Hypothyroidism
Intervention: Drug: Levothyroxine
8 Recruiting Phenotypic Specific Communication Intervention for Children With Down Syndrome
Conditions: Language Impairment;   Down Syndrome
Intervention: Behavioral: Jasper-EMT with words and AAC
9 Recruiting Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite
Condition: Down Syndrome
Intervention: Procedure: custom orthotics
10 Recruiting Natural History of Amyloid Deposition in Adults With Down Syndrome
Condition: Down Syndrome
Intervention:
11 Recruiting Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children
Condition: Down Syndrome
Intervention: Drug: thyroid hormone and folinic acid
12 Recruiting Non Invasive Prenatal Testing of Down Syndrome
Condition: Down Syndrome
Interventions: Procedure: Non Invasive Prenatal Testing;   Procedure: Invasive Prenatal Testing
13 Recruiting Trisomy 21 in Adulthood
Condition: Down Syndrome
Intervention: Genetic: karyotype
14 Recruiting Down Syndrome Memantine Follow-up Study
Conditions: Down Syndrome;   Intellectual Disability
Interventions: Drug: Memantine;   Drug: Placebo
15 Unknown  Neuromuscular Characteristics of Individuals With Down Syndrome (DS)
Condition: Down Syndrome
Intervention: Other: muscle strength
16 Unknown  Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down Syndrome
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:
17 Unknown  Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:
18 Recruiting Comparison of Bispectral Index Values in Patients With and Without Down's Syndrome
Condition: Down Syndrome
Intervention: Device: monitoring BIS in both groups
19 Recruiting Investigation of the Safety of Intranasal Glulisine in Down Syndrome
Condition: Down Syndrome
Interventions: Drug: Insulin glulisine;   Drug: Saline
20 Not yet recruiting Relationship Between Down Syndrome (DS) and Alzheimer's Disease (AD)
Conditions: Down Syndrome;   Alzheimer's Dementia
Interventions: Procedure: biospecimen collection;   Other: cognitive assessments;   Other: caregiver questionnaire;   Procedure: Florbetapir F18 imaging;   Procedure: MRI;   Procedure: Fludeoxyglucose F18 (FDG);   Procedure: Tau Pet;   Procedure: Actigraphy

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Indicates status has not been verified in more than two years