55 studies found for:    Open Studies | "Down Syndrome"
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Rank Status Study
21 Unknown  Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:
22 Recruiting Comparison of Bispectral Index Values in Patients With and Without Down's Syndrome
Condition: Down Syndrome
Intervention: Device: monitoring BIS in both groups
23 Recruiting Investigation of the Safety of Intranasal Glulisine in Down Syndrome
Condition: Down Syndrome
Interventions: Drug: Insulin glulisine;   Drug: Saline
24 Not yet recruiting Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome
Conditions: Down Syndrome;   Polyendocrinopathies, Autoimmune;   Respiratory Tract Infections;   Autoimmunity
Intervention: Other: Phlebotomy
25 Recruiting A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)
Condition: Down Syndrome
Interventions: Drug: Placebo;   Drug: RG1662
26 Recruiting Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model
Condition: Down Syndrome
Intervention: Genetic: Skeletal Status Assessment of a Down Syndrome Population
27 Recruiting Feasibility and Dose Tolerability of HD-tDCS in Healthy Adults and Adults With Down Syndrome
Condition: Down Syndrome
Intervention: Device: High definition transcranial direct current stimulation
28 Not yet recruiting A Study of RG1662 in Down Syndrome Among Children 6 to 11 Years of Age
Condition: Down Syndrome
Interventions: Drug: Placebo;   Drug: RG1662
29 Recruiting A Pilot Study to Evaluate the Safety and Efficacy of the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea
Conditions: Sleep Apnea, Obstructive;   Down Syndrome
Intervention: Device: Inspire® Upper Airway Simulation System, Model 3024 IPG
30 Recruiting Non-drug Study to Assess the Suitability of Assessment Scales in Japanese Individuals With Down Syndrome Aged 6-30
Condition: Down Syndrome
Intervention:
31 Recruiting Non-drug Study to Evaluate the Suitability of Neurocognitive Tests and Functioning Scales for the Measurement of Cognitive and Functioning Changes in Children With Down Syndrome
Condition: Down Syndrome
Intervention: Other: No Intervention
32 Unknown  Frequency of Metabolic Syndrome in Down Syndrome Patients
Conditions: Metabolic Syndrome X;   Down Syndrome
Intervention:
33 Recruiting Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
Conditions: Down Syndrome;   Fetal Aneuploidy
Intervention:
34 Recruiting Non-Invasive Chromosomal Evaluation of Trisomy Study
Conditions: Aneuploidy;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Down Syndrome
Intervention:
35 Recruiting Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies
Conditions: Down Syndrome;   Aneuploidy
Intervention: Other: Maternal blood draw of 30 to 50ml
36 Not yet recruiting The Effect of Bifocals in Children With Down Syndrome
Conditions: Visual Acuity at Near;   Accuracy of Accommodation;   Prevention of Strabismus;   Task Readiness
Interventions: Device: bifocals;   Device: single vision glasses
37 Recruiting Non-Invasive Screening for Fetal Aneuploidy
Conditions: Down Syndrome;   Edwards Syndrome
Intervention: Other: Maternal Blood Draw
38 Recruiting Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation Pregnancies
Conditions: Down Syndrome;   Edwards Syndrome;   Patau Syndrome;   Turner Syndrome
Intervention:
39 Recruiting DIR/ Floortime™ Parent Training Intervention for the Children With Developmental Disabilities
Conditions: Cerebral Palsy;   Down's Syndrome;   Delayed Development
Interventions: Behavioral: Parent training;   Behavioral: Routine care
40 Unknown  Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool
Condition: Down Syndrome (DS)
Intervention: Dietary Supplement: Epigallocatechin-3-gallate (EGCG)

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Indicates status has not been verified in more than two years