48 studies found for:    Open Studies | "Down Syndrome"
Show Display Options
Rank Status Study
21 Not yet recruiting Relationship Between Down Syndrome (DS) and Alzheimer's Disease (AD)
Conditions: Down Syndrome;   Alzheimer's Dementia
Interventions: Procedure: biospecimen collection;   Other: cognitive assessments;   Other: caregiver questionnaire;   Procedure: Florbetapir F18 imaging;   Procedure: MRI;   Procedure: Fludeoxyglucose F18 (FDG);   Procedure: Tau Pet;   Procedure: Actigraphy
22 Not yet recruiting Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome
Conditions: Down Syndrome;   Polyendocrinopathies, Autoimmune;   Respiratory Tract Infections;   Autoimmunity
Intervention: Other: Phlebotomy
23 Recruiting A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)
Condition: Down Syndrome
Interventions: Drug: Placebo;   Drug: RG1662
24 Recruiting Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome
Condition: Down Syndrome
Interventions: Biological: ACI-24 low dose;   Biological: ACI-24 high dose;   Biological: Placebo
25 Recruiting A Study of RG1662 in Down Syndrome Among Children 6 to 11 Years of Age
Condition: Down Syndrome
Interventions: Drug: Placebo;   Drug: RG1662
26 Recruiting A Pilot Study to Evaluate the Safety and Efficacy of the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea
Conditions: Sleep Apnea, Obstructive;   Down Syndrome
Intervention: Device: Inspire® Upper Airway Simulation System, Model 3024 IPG, and any subsequent iteration thereof that are approved under P130008 for the treatment of obstructive sleep apnea
27 Unknown  Frequency of Metabolic Syndrome in Down Syndrome Patients
Conditions: Metabolic Syndrome X;   Down Syndrome
Intervention:
28 Recruiting Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
Conditions: Down Syndrome;   Fetal Aneuploidy
Intervention:
29 Recruiting Non-Invasive Chromosomal Evaluation of Trisomy Study
Conditions: Aneuploidy;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Down Syndrome
Intervention:
30 Recruiting Digital Dysmorphology Project
Condition: Down Syndrome
Intervention: Device: photographs
31 Recruiting Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies
Conditions: Down Syndrome;   Aneuploidy
Intervention: Other: Maternal blood draw of 30 to 50ml
32 Recruiting The Effect of Bifocals in Children With Down Syndrome
Conditions: Visual Acuity at Near;   Accuracy of Accommodation;   Prevention of Strabismus;   Task Readiness
Interventions: Device: bifocals;   Device: single vision glasses
33 Recruiting Rocky Mountain Alzheimer's Disease Center Longitudinal Biomarker and Clinical Phenotyping Study
Conditions: Alzheimer Disease;   Down Syndrome;   Mild Cognitive Impairment
Intervention:
34 Recruiting Weight Management for Adolescents With IDD
Conditions: Developmental Disabilities;   Weight Loss;   Body Weight;   Down Syndrome;   Body Weight Changes;   Intellectual Disability
Interventions: Dietary Supplement: Enhanced Stop Light Diet (eSLD);   Dietary Supplement: Conventional Diet (CD);   Behavioral: Face-to-face (FTF);   Behavioral: Technology (TECH);   Other: iPad with FaceTime
35 Recruiting Whole Blood Specimen Collection From Pregnant Subjects
Conditions: Down Syndrome;   Edwards Syndrome;   Patau Syndrome;   Klinefelter Syndrome;   Turner Syndrome;   DiGeorge Syndrome;   Perinatal Infections
Intervention: Other: Observational - no intervention
36 Recruiting Non-Invasive Screening for Fetal Aneuploidy
Conditions: Down Syndrome;   Edwards Syndrome
Intervention: Other: Maternal Blood Draw
37 Recruiting Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma
Conditions: Adult B Lymphoblastic Lymphoma;   Childhood B Acute Lymphoblastic Leukemia;   Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34;q11.2); BCR-ABL1;   Childhood B Lymphoblastic Lymphoma;   Down Syndrome;   Stage I B Lymphoblastic Lymphoma;   Stage II B Lymphoblastic Lymphoma;   Untreated Adult Acute Lymphoblastic Leukemia;   Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: Drug: Cyclophosphamide;   Drug: Cytarabine;   Drug: Dexamethasone;   Drug: Doxorubicin Hydrochloride;   Other: Laboratory Biomarker Analysis;   Drug: Leucovorin Calcium;   Drug: Mercaptopurine;   Drug: Methotrexate;   Drug: Pegaspargase;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Drug: Thioguanine;   Drug: Vincristine Sulfate
38 Recruiting DIR/ Floortime™ Parent Training Intervention for the Children With Developmental Disabilities
Conditions: Cerebral Palsy;   Down's Syndrome;   Delayed Development
Interventions: Behavioral: Parent training;   Behavioral: Routine care
39 Unknown  Non-Invasive Determination of Fetal Chromosome Abnormalities
Conditions: Down Syndrome (Trisomy 21);   Edward's Syndrome (Trisomy 18);   Patau Syndrome (Trisomy 13);   Klinefelter Syndrome (47, XXY);   and Other Chromosome;   Abnormalities.
Intervention:
40 Recruiting Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA
Conditions: Microdeletion Syndromes;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Sex Chromosome Abnormalities
Intervention:

First Page    Show previous page of results Previous Page (1-20) Studies Shown (21-40) Next Page (41-48) Show next page of results    Last Page
Indicates status has not been verified in more than two years