57 studies found for:    Open Studies | "Down Syndrome"
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Rank Status Study
21 Unknown  Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down Syndrome
Conditions: Down Syndrome;   Alzheimer's Disease
22 Unknown  Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia
Conditions: Down Syndrome;   Alzheimer's Disease
23 Recruiting Comparison of Bispectral Index Values in Patients With and Without Down's Syndrome
Condition: Down Syndrome
Intervention: Device: monitoring BIS in both groups
24 Recruiting Investigation of the Safety of Intranasal Glulisine in Down Syndrome
Condition: Down Syndrome
Interventions: Drug: Insulin glulisine;   Drug: Saline
25 Not yet recruiting Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome
Conditions: Down Syndrome;   Polyendocrinopathies, Autoimmune;   Respiratory Tract Infections;   Autoimmunity
Intervention: Other: Phlebotomy
26 Recruiting A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)
Condition: Down Syndrome
Interventions: Drug: Placebo;   Drug: RG1662
27 Recruiting Feasibility and Dose Tolerability of HD-tDCS in Healthy Adults and Adults With Down Syndrome
Condition: Down Syndrome
Intervention: Device: High definition transcranial direct current stimulation
28 Recruiting A Study of RG1662 in Down Syndrome Among Children 6 to 11 Years of Age
Condition: Down Syndrome
Interventions: Drug: Placebo;   Drug: RG1662
29 Recruiting A Pilot Study to Evaluate the Safety and Efficacy of the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea
Conditions: Sleep Apnea, Obstructive;   Down Syndrome
Intervention: Device: Inspire® Upper Airway Simulation System, Model 3024 IPG
30 Recruiting Non-drug Study to Assess the Suitability of Assessment Scales in Japanese Individuals With Down Syndrome Aged 6-30
Condition: Down Syndrome
31 Recruiting Non-drug Study to Evaluate the Suitability of Neurocognitive Tests and Functioning Scales for the Measurement of Cognitive and Functioning Changes in Children With Down Syndrome
Condition: Down Syndrome
Intervention: Other: No Intervention
32 Unknown  Frequency of Metabolic Syndrome in Down Syndrome Patients
Conditions: Metabolic Syndrome X;   Down Syndrome
33 Recruiting Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
Conditions: Down Syndrome;   Fetal Aneuploidy
34 Recruiting Non-Invasive Chromosomal Evaluation of Trisomy Study
Conditions: Aneuploidy;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Down Syndrome
35 Recruiting Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies
Conditions: Down Syndrome;   Aneuploidy
Intervention: Other: Maternal blood draw of 30 to 50ml
36 Not yet recruiting The Effect of Bifocals in Children With Down Syndrome
Conditions: Visual Acuity at Near;   Accuracy of Accommodation;   Prevention of Strabismus;   Task Readiness
Interventions: Device: bifocals;   Device: single vision glasses
37 Recruiting Weight Management for Adolescents With IDD
Conditions: Developmental Disabilities;   Weight Loss;   Body Weight;   Down Syndrome;   Body Weight Changes;   Intellectual Disability
Interventions: Dietary Supplement: Enhanced Stop Light Diet (eSLD);   Dietary Supplement: Conventional Diet (CD);   Behavioral: Face-to-face (FTF);   Behavioral: Technology (TECH);   Other: iPad with FaceTime
38 Recruiting Non-Invasive Screening for Fetal Aneuploidy
Conditions: Down Syndrome;   Edwards Syndrome
Intervention: Other: Maternal Blood Draw
39 Recruiting Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma
Conditions: Adult B Lymphoblastic Lymphoma;   Childhood B Acute Lymphoblastic Leukemia;   Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34;q11.2); BCR-ABL1;   Childhood B Lymphoblastic Lymphoma;   Down Syndrome;   Stage I B Lymphoblastic Lymphoma;   Stage II B Lymphoblastic Lymphoma;   Untreated Adult Acute Lymphoblastic Leukemia;   Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: Drug: Cyclophosphamide;   Drug: Cytarabine;   Drug: Dexamethasone;   Drug: Doxorubicin Hydrochloride;   Other: Laboratory Biomarker Analysis;   Drug: Leucovorin Calcium;   Drug: Mercaptopurine;   Drug: Methotrexate;   Drug: Pegaspargase;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Drug: Thioguanine;   Drug: Vincristine Sulfate
40 Recruiting DIR/ Floortime™ Parent Training Intervention for the Children With Developmental Disabilities
Conditions: Cerebral Palsy;   Down's Syndrome;   Delayed Development
Interventions: Behavioral: Parent training;   Behavioral: Routine care

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Indicates status has not been verified in more than two years