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43 studies found for:    Open Studies | "Down Syndrome"
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Rank Status Study
1 Recruiting Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite
Condition: Down Syndrome
Intervention: Procedure: custom orthotics
2 Not yet recruiting Physiological Abnormalities Associated With Down Syndrome
Condition: Down Syndrome
Intervention:
3 Recruiting Trisomy 21 in Adulthood
Condition: Down Syndrome
Intervention: Genetic: karyotype
4 Recruiting Non Invasive Prenatal Testing of Down Syndrome
Condition: Down Syndrome
Interventions: Procedure: Non Invasive Prenatal Testing;   Procedure: Invasive Prenatal Testing
5 Recruiting Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children
Condition: Down Syndrome
Intervention: Drug: thyroid hormone and folinic acid
6 Not yet recruiting Effects of Karate in Adolescents With Down Syndrome
Condition: Down Syndrome
Intervention: Other: PKSA karate class
7 Recruiting Comparison of Bispectral Index Values in Patients With and Without Down's Syndrome
Condition: Down Syndrome
Intervention: Device: monitoring BIS in both groups
8 Recruiting Investigation of the Safety of Intranasal Glulisine in Down Syndrome
Condition: Down Syndrome
Interventions: Drug: Insulin glulisine;   Drug: Saline
9 Recruiting Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome
Condition: Down Syndrome
Interventions: Biological: ACI-24 low dose;   Biological: ACI-24 high dose;   Biological: Placebo
10 Recruiting Down Syndrome Metabolic Health Study
Conditions: Down Syndrome;   Trisomy 21
Intervention:
11 Recruiting Treatment of Sleep Disturbances in School-age Children With Down Syndrome
Condition: Down Syndrome
Interventions: Behavioral: Behavioral Sleep Treatment;   Behavioral: Standard of care sleep treatment enhanced with psychoeducation
12 Recruiting Phenotypic Specific Communication Intervention for Children With Down Syndrome
Conditions: Language Impairment;   Down Syndrome
Intervention: Behavioral: Jasper-EMT with words and AAC
13 Recruiting Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
Conditions: Down Syndrome;   Subclinical Hypothyroidism
Intervention: Drug: Levothyroxine
14 Recruiting Down Syndrome Memantine Follow-up Study
Conditions: Down Syndrome;   Intellectual Disability
Interventions: Drug: Memantine;   Drug: Placebo
15 Recruiting Neurocognitive and Psychosocial Outcomes in Survivors of Childhood Leukemia With Down Syndrome
Conditions: Leukemia;   Down Syndrome
Intervention:
16 Recruiting The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients
Condition: Down Syndrome
Interventions: Drug: Sevoflurane;   Drug: Desflurane
17 Recruiting Nicotine Treatment of Cognitive Decline in Down Syndrome
Conditions: Down Syndrome;   Mild Cognitive Impairment
Interventions: Drug: Low Dose Nicotine (7mg);   Drug: Moderate Dose Nicotine (14mg)
18 Recruiting Digital Dysmorphology Project
Condition: Down Syndrome
Intervention: Device: photographs
19 Recruiting Relationship Between Down Syndrome (DS) and Alzheimer's Disease (AD)
Conditions: Down Syndrome;   Alzheimer's Dementia
Interventions: Procedure: biospecimen collection;   Other: cognitive assessments;   Other: caregiver questionnaire;   Procedure: Florbetapir F18 imaging;   Procedure: MRI;   Procedure: Fludeoxyglucose F18 (FDG);   Procedure: Tau Pet;   Procedure: Actigraphy
20 Recruiting A Pilot Study to Evaluate the Safety and Efficacy of the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea
Conditions: Sleep Apnea, Obstructive;   Down Syndrome
Intervention: Device: Inspire® Upper Airway Simulation System, Model 3024 IPG, and any subsequent iteration thereof that are approved under P130008 for the treatment of obstructive sleep apnea

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Study has passed its completion date and status has not been verified in more than two years.