Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
361 studies found for:    Open Studies | "Diabetes Mellitus, Type 1"
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Rank Status Study
1 Recruiting Accuracy of Two CGM Systems Tested Simultaneously in Ambulatory Patients With Type 1 Diabetes
Conditions: Diabetes Mellitus, Type 1;   Blood Glucose
Interventions: Device: Guardian Enlite sensor;   Device: Dexcom G4 platinum sensor
2 Recruiting Evaluation of Vildagliptin (Galvus®) as add-on to Insulin in New-onset Type 1 Diabetes Mellitus
Conditions: Type 1 Diabetes;   Insulin Dependent Diabetes;   Juvenile Onset Diabetes Mellitus;   Autoimmune Diabetes
Intervention: Drug: Vildagliptin
3 Recruiting Natural History Study of the Development of Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Intervention:
4 Recruiting Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus
Condition: Diabetes Mellitus, Type 1
Intervention: Drug: Oral Insulin
5 Unknown  Polyclonal Anti-T-Lymphocyte Globulin (ATG) in Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Intervention: Drug: Polyclonal anti-T-cell antibodies
6 Recruiting A Study of Effects of Canagliflozin as Add-on Therapy to Insulin in the Treatment of Participants With Type 1 Diabetes Mellitus (T1DM)
Condition: Diabetes Mellitus, Type 1
Interventions: Drug: Canagliflozin 100 mg;   Drug: Canagliflozin 300 mg;   Drug: Placebo
7 Not yet recruiting Unified Safety System (USS) Virginia Closed-Loop Versus Sensor Augmented Pump Therapy for Oversight Control in Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1 (T1DM)
Intervention: Device: Diabetes Assistant (DiAs)
8 Recruiting ATG-GCSF in New Onset Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Interventions: Drug: Anti-Thymocyte Globulin (ATG)/Placebo;   Drug: Granulocyte colony stimulating factor (GCSF)
9 Recruiting Optimizing Closed-Loop Control of Type 1 Diabetes Mellitus in Adolescents
Condition: Diabetes Mellitus, Type 1
Intervention: Device: Diabetes Assistant (DiAs)
10 Recruiting Effect of Methyldopa on MHC Class II Antigen Presentation in Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Intervention: Drug: Methyldopa
11 Unknown  Influence of Vitamin D on Vascular Function in Adolescents and Young Adults With Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Intervention: Dietary Supplement: Vitamin D
12 Unknown  Immune Intervention With Rituximab to Preserve Beta Cell Function in Early Onset Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Intervention: Drug: rituximab
13 Recruiting A Study To Assess The Safety Of PF-06342674 In Adults With Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Interventions: Drug: Placebo;   Biological: PF-06342674 Dose A;   Biological: PF-06342674 Dose B;   Biological: PF-06342674 Dose C;   Biological: PF-06342674 Dose D
14 Recruiting Albiglutide Versus Placebo in Insulin-treated Subjects With New-onset Type 1 Diabetes Mellitus
Condition: Diabetes Mellitus, Type 1
Interventions: Biological: Albiglutide weekly injection;   Biological: Placebo weekly injection;   Biological: Insulin
15 Recruiting Automated Closed-loop in Children and Adolescents With Type 1 Diabetes
Conditions: Diabetes Mellitus;   Diabetes Mellitus, Type 1;   Glucose Metabolism Disorders;   Endocrine System Diseases;   Autoimmune Diseases
Intervention: Device: Closed-loop (Android Closed-Loop platform)
16 Recruiting Postprandial Blood Glucose Control and Gastric Emptying in Type 1 Diabetes: Pathogenetic Factors and Therapeutic Options
Condition: Diabetes Mellitus, Type 1
Interventions: Other: gastric emptying test;   Other: gut hormones determination;   Other: Continuous Glucose Monitoring;   Drug: Insulin single bolus;   Drug: Insulin double-wave bolus
17 Recruiting Imatinib Treatment in Recent Onset Type 1 Diabetes Mellitus
Conditions: Diabetes Mellitus, Type I;   Diabetes Mellitus, Insulin-Dependent, 1;   Type 1 Diabetes Mellitus;   Insulin-Dependent Diabetes Mellitus 1;   IDDM
Interventions: Drug: Imatinib Mesylate;   Drug: Placebo (For imatinib mesylate)
18 Not yet recruiting Type 1 Diabetes and the Brain in Children
Condition: Diabetes Mellitus, Type 1
Intervention: Other: Observational
19 Recruiting Islet Transplantation in Patients With "Brittle" Type I Diabetes
Condition: Diabetes Mellitus, Type 1
Interventions: Biological: Allogenic islet cells (human, U. Chicago);   Procedure: Intraportal infusion of islet cells
20 Recruiting REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL)
Condition: Diabetes Mellitus, Type 1
Interventions: Drug: Metformin;   Drug: Placebo

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Indicates status has not been verified in more than two years