Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
618 studies found for:    Open Studies | "Bone Marrow Diseases"
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Rank Status Study
21 Unknown  Anesthesia Induction in Patients Undergoing Surgery for Cervical Myelopathy
Condition: Spinal Cord Diseases
Intervention: Drug: anaesthetics: sevofluorane
22 Recruiting Baxter: Actifuse SHAPE vs DBX in ACC
Conditions: Cervical Spine Degenerative Disease Nos;   Cervical Spondylosis With Myelopathy
Interventions: Device: Actifuse SHAPE;   Device: Autograft with Demineralized Bone Matrix
23 Recruiting Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
Conditions: Metabolic Disorders;   Hematologic, Immune, or Bone Marrow Disorders;   Hemoglobinopathies;   Non-malignant Disorders
Interventions: Drug: Transplant conditioning regimen of alemtuzumab, fludarabine, and melphalan;   Drug: Transplant conditioning regimen of hydroxyurea, campath, fludarabine, thiotepa, & melphalan
24 Unknown  Safety and Efficacy Study of Umbilical Cord/Placenta-Derived Mesenchymal Stem Cells to Treat Severe Aplastic Anemia
Condition: Aplastic Anemia
Interventions: Other: Human umbilical cord-derived MSCs and cyclosporin A;   Other: cyclosporin A
25 Recruiting Oral Pacritinib Versus Best Available Therapy to Treat Myelofibrosis With Thrombocytopenia
Conditions: Primary Myelofibrosis;   Post-polycythemia Vera Myelofibrosis;   Post-essential Thrombocythemia Myelofibrosis
Interventions: Drug: Pacritinib;   Drug: Best Available Therapy
26 Unknown  Safety and Efficacy Study of Umbilical Cord/Placenta-Derived Mesenchymal Stem Cells to Treat Myelodysplastic Syndromes
Condition: Myelodysplastic Syndromes
Interventions: Other: Human umbilical cord-derived MSCs;   Other: cyclosporine A  (CsA)
27 Recruiting Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MF
Conditions: Primary Myelofibrosis;   Post-Polycythemic Vera Myelofibrosis;   Post-Essential Thrombocythemia Myelofibrosis
Intervention: Drug: NS-018
28 Unknown  Bortezomib and Low Dose Cytarabine in the Treatment of High-Risk Myelodysplastic Syndromes
Condition: Myelodysplastic Syndromes
Intervention: Drug: Bortezomib
29 Recruiting Prospective Observational Study Of Patients With Polycythemia Vera In US Clinical Practices (REVEAL)
Condition: Polycythemia Vera
Intervention:
30 Recruiting A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia
Condition: Leukemia, Myelogenous, Chronic, Breakpoint Cluster Region-Abelson Proto-oncogene (BCR-ABL) Positive
Interventions: Drug: Bosutinib;   Drug: Imatinib
31 Recruiting Ruxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Available Therapy.
Condition: Polycythemia Vera
Interventions: Drug: Best Available Therapy;   Drug: ruxolitinib
32 Recruiting AOP2014 in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study.
Condition: Polycythemia Vera
Intervention: Drug: Pegylated-Proline-interferon alpha-2b
33 Available Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant
Conditions: Acute Lymphoblastic Leukemia;   Acute Myeloid Leukemia;   Chronic Myeloid Leukemia;   Myelodysplastic Syndrome;   Lymphomas;   Bone Marrow Failure;   Hemoglobinopathy;   Immune Deficiency;   Osteopetrosis;   Cytopenias;   White Blood Cell Abnormalities;   Red Blood Cell Abnormalities
Intervention: Biological: CD34+ enriched, T Cell Depleted donor stem cell product
34 Recruiting Raltegravir for HAM/TSP
Conditions: HAM/TSP;   HTLV-1
Intervention: Drug: Raltegravir
35 Recruiting CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease
Conditions: Bone Marrow Failure Syndrome;   Severe Aplastic Anemia;   Severe Congenital Neutropenia;   Amegakaryocytic Thrombocytopenia;   Diamond-Blackfan Anemia;   Schwachman Diamond Syndrome;   Primary Immunodeficiency Syndromes;   Acquired Immunodeficiency Syndromes;   Histiocytic Syndrome;   Familial Hemophagocytic Lymphocytosis;   Lymphohistiocytosis;   Macrophage Activation Syndrome;   Langerhans Cell Histiocytosis (LCH);   Hemoglobinopathies;   Sickle Cell Disease;   Sickle Cell-beta-thalassemia
Intervention: Biological: CliniMacs (PLUS) Reagent System
36 Recruiting Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma
Conditions: Metastatic Ewing Sarcoma;   Metastatic Malignant Neoplasm to the Bone;   Metastatic Malignant Neoplasm to the Bone Marrow;   Metastatic Malignant Neoplasm to the Lung;   Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone;   Peripheral Primitive Neuroectodermal Tumor of Soft Tissues
Interventions: Drug: Vincristine Sulfate;   Drug: Doxorubicin Hydrochloride;   Drug: Cyclophosphamide;   Drug: Ifosfamide;   Drug: Etoposide;   Biological: Ganitumab;   Procedure: Therapeutic Surgical Procedure;   Radiation: Stereotactic Radiosurgery;   Radiation: External Beam Radiation Therapy;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study
37 Recruiting Bone Metastasis in Breast Cancer
Conditions: Metastatic Breast Carcinoma With Bone Metastasis Only;   Primary Surgery
Interventions: Procedure: Surgery;   Drug: Systemic therapy
38 Recruiting Prospective Evaluation of Interventional Studies on Bone Metastases - the PRESENT Cohort
Condition: Bone Metastases
Intervention:
39 Recruiting A Randomized Trial Evaluating Rapid Delivery of Dose Escalated Hypofractionated Radiotherapy for Patients Diagnosed With Bone Metastases for Effective Palliation of Symptoms
Condition: Bone Metastases
Interventions: Radiation: Hypofractionated Radiation Treatment;   Radiation: One Radiation Treatment;   Behavioral: Questionnaire
40 Recruiting Dual Energy Computed Tomography (CT) in Finding Bone Metastases in Patients With Cancer
Conditions: Malignant Neoplasm;   Metastatic Malignant Neoplasm to the Bone
Interventions: Radiation: virtual non-calcium dual-energy computed tomography;   Radiation: computed tomography

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