45 studies found for:    Open Studies | "Ataxia"
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Open Studies | "Ataxia" (45 records)
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Rank Status Study
1 Recruiting Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias
Conditions: Spinocerebellar Ataxia Type 1;   Spinocerebellar Ataxia Type 2;   Spinocerebellar Ataxia Type 3;   Spinocerebellar Ataxia Type 6
Intervention: Genetic: All Participants
2 Unknown  Immunogenicity of Pneumococcal Vaccines in Ataxia-telangiectasia Patients
Condition: Ataxia Telangiectasia
Interventions: Biological: Prevenar® (7-valent pneumococcal conjugate vaccine);   Biological: Pneumovax® (pneumococcal polysaccharide vaccine)
3 Unknown  Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT)
Conditions: Ataxia Telangiectasia;   Growth Failure
Intervention: Drug: Somatropin, Clonidine, L-Arginin-Hydrochloride, Estradiol valerate
4 Not yet recruiting Cell-Based Approaches For Modeling and Treating Ataxia-Telangiectasia
Condition: Ataxia-Telangiectasia (A-T)
Interventions: Other: with gene correction;   Other: without gene correction
5 Not yet recruiting Functional and Structural Imaging and Motor Control in Spinocerebellar Ataxia
Condition: Spinocerebellar Ataxia
Interventions: Behavioral: Error-reduction;   Behavioral: International Cooperative Ataxia Rating Scale;   Behavioral: Scale for the Assessment and Rating of Ataxia
6 Recruiting An Open-label Trial of Intravenous Immune Globulin (IVIG)in Treating Spinocerebellar Ataxias
Condition: Spinocerebellar Ataxias
Intervention: Drug: Intravenous Immune Globulin (IVIG)
7 Recruiting Biomarkers in Friedreich's Ataxia
Condition: Friedreich's Ataxia
8 Recruiting Efficacy and Safety Study of Mesenchymal Stem Cells (Stemchymal®) in Polyglutamine Spinocerebellar Ataxia
Condition: Cerebellar Ataxia
Interventions: Biological: Stemchymal®;   Procedure: Excipients
9 Recruiting Methylprednisolone Treatment of Friedreich Ataxia
Condition: Friedreich Ataxia
Intervention: Drug: Methylprednisolone
10 Recruiting Characterization of the Cardiac Phenotype of Friedreich's Ataxia (FRDA)
Condition: Friedreich's Ataxia
Interventions: Procedure: Cardiac magnetic resonance imaging (CMR);   Procedure: Exercise-stress test;   Procedure: Echocardiogram (ECHO);   Procedure: Cardiac-related blood studies
11 Recruiting Patient Registry of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS)
Condition: Friedreich's Ataxia
12 Recruiting Clinical Study to Evaluate the Safety and Efficacy BMMNC in Cerebellar Ataxia
Condition: Cerebellar Ataxia
Intervention: Biological: Intravenous transfer of of Bone Marrow derived Mono Nuclear Stem Cell (BMMNCs)
13 Unknown  SPATAX: Clinical and Genetic Analysis of Cerebellar Ataxias and Spastic Paraplegias
Conditions: Cerebellar Ataxias;   Spastic Paraplegias
14 Recruiting Oxidative Stress, Low Grade Inflammation, Tissue Breakdown and Biomarkers in Cerebrospinal Fluid of A-T
Condition: Ataxia Telangiectasia
Intervention: Procedure: Lumbar puncture
15 Recruiting RTA 408 Capsules in Patients With Friedreich's Ataxia - MOXIe
Condition: Friedreich Ataxia
Interventions: Drug: Omaveloxolone Capsules, 2.5 mg;   Drug: Omaveloxolone Capsules, 5 mg;   Drug: Omaveloxolone Capsules, 10 mg;   Drug: Placebo;   Device: Omaveloxolone Capsules, 20 mg;   Drug: Omaveloxolone Capsules, TBD mg
16 Recruiting A First in Human Study of RT001 in Patients With Friedreich's Ataxia
Condition: Friedreich's Ataxia
Interventions: Drug: RT001;   Drug: RT001 comparator
17 Recruiting An Open-label Study of the Effects of Acetyl-L-Carnitine on Cardiovascular Outcomes in Friedreich's Ataxia
Condition: Friedreich's Ataxia
Intervention: Drug: Acetyl-L-Carnitine
18 Not yet recruiting Safety, Tolerability and Efficacy of ACTIMMUNE Dose Escalation in Friedreich's Ataxia Study
Condition: Friedreich's Ataxia
Intervention: Drug: Interferon γ-1b
19 Recruiting Safety, Tolerability and Efficacy of ACTIMMUNE Dose Escalation in Friedreich's Ataxia
Condition: Friedreich's Ataxia
Interventions: Drug: Interferon γ-1b;   Drug: Placebo
20 Unknown  Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Hereditary Ataxia
Condition: Hereditary Ataxia
Intervention: Biological: human umbilical cord mesenchymal stem cells

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Indicates status has not been verified in more than two years