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50 studies found for:    Open Studies | "Anus Diseases"
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Rank Status Study
1 Not yet recruiting Efficacy Study of Chemoradiotherapy With or Without Paclitaxel in Squamous-cell Anal Carcinoma Patients
Conditions: Anus Neoplasms;   Carcinoma, Squamous Cell;   Anus Diseases;   Neoplasms;   Neoplasms, Squamous Cell;   Carcinoma
Interventions: Drug: Paclitaxel;   Drug: Capecitabine;   Drug: Mitomycins;   Radiation: Radiotherapy
2 Unknown  Comparison of Biofeedback vs. Botox Injection to Treat Levator Ani Syndrome
Condition: Levator Ani Syndrome With Pain and/or Constipation Symptoms.
Interventions: Behavioral: Biofeedback therapy;   Procedure: Botulinum Toxin Type A Injection
3 Not yet recruiting Pembrolizumab in Refractory Metastatic Anal Cancer
Condition: Anal Cancer
Intervention: Drug: Pembrolizumab
4 Not yet recruiting MED-C Registry: Advanced Malignancy or Myelodysplasia, Tested by Standard Sequencing and Treated by Physician Choice
Conditions: Neoplasms;   Lung Neoplasms;   Colon Neoplasms;   Breast Neoplasms;   Pancreatic Neoplasms;   Prostate Neoplasms;   Kidney Neoplasms;   Liver Neoplasms;   Rectal Neoplasms;   Hematologic Neoplasms;   Multiple Myeloma;   Myelodysplastic Syndromes;   Ovarian Neoplasms;   Bladder Neoplasms;   Testicular Neoplasms;   Endometrial Neoplasms;   Brain Neoplasms;   Biliary Tract Neoplasms;   Head and Neck Neoplasms;   Uterine Cervical Neoplasms;   Skin Neoplasms;   Melanoma;   Gastric Neoplasms;   Anal Neoplasms;   Sarcoma
Intervention: Other: Provider determined
5 Not yet recruiting Early Rectal Cancer: Endoscopic Submucosal Dissection or Transanal Endoscopic Microsurgery?
Condition: Anal Cancer
Intervention: Procedure: Local excision for early rectal cancer
6 Recruiting New Strategies to Assess Anal Cancer Risk In Women
Conditions: Human Immunodeficiency Virus (HIV);   Human Papillomavirus (HPV)
Interventions: Procedure: Perianal and Digital Anorectal Exam;   Procedure: Cervical Swabs;   Procedure: Anal Swabs;   Procedure: High Resolution Anoscopy (HRA)
7 Not yet recruiting Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal Cancer
Conditions: Cancer of Head and Neck;   Cancer of Cervix;   Cancer of Anus
Interventions: Drug: DPX-E7 vaccine;   Drug: Cyclophosphamide
8 Recruiting E7 TCR T Cells With or Without PD-1 Blockade for Human Papillomavirus-Associated Cancers
Conditions: Cervical Cancer;   Vaginal Cancer;   Anal Cancer;   Penile Cancer;   Oropharyngeal Cancer
Interventions: Biological: E7 TCR cells;   Drug: pembrolizumab;   Drug: aldesleukin;   Drug: fludarabine;   Drug: cyclophosphamide
9 Not yet recruiting A Prospective, Open-Label, Multi-center Comparison of Lymphoseek Identified Lymph Nodes and Clinically Identified Lymph Nodes of Subjects With Known Cancer of the Anus
Condition: Anal Cancer
Intervention: Drug: Lymphoseek
10 Recruiting Anal Cytology Collection Procedures in Predicting High-Grade Anal Dysplasia in Men Who Have Sex With Men
Conditions: Anal Carcinoma;   HIV Infection;   Human Papillomavirus Infection
Interventions: Procedure: Cytology Specimen Collection Procedure;   Other: Laboratory Biomarker Analysis
11 Recruiting Shared Decision Making With Anal Cancer Patients on Radiation Dose
Condition: Anal Cancer
Interventions: Radiation: 2.15 gray and 1.8 gray. Max. 6 weeks.;   Radiation: 2.15 gray and 1.8 gray. Max. 5 weeks.
12 Recruiting Study of SIB-IMRT in Combination With 5-FU and Mitomycin-C Among Patients With Locally Advanced Anal Canal Cancer: Efficacy, Safety and Quality of Life
Condition: Locally Advanced Anal Canal Cancer
Interventions: Drug: 5Fluorouracile and Mitomycin-C;   Radiation: Simultaneously integrated boost of intensity modulated radiation therapy (SIB-IMRT) by tomotherapy
13 Not yet recruiting A Phase I Study of Photodynamic Therapy (PDT) for High-grade Anal Dysplasia and Microinvasive Anal Cancer
Condition: Anal Cancer
Intervention: Drug: Gliolan
14 Recruiting Individual Following in Anal Cancer With PET/CT
Condition: Anal Cancer
Intervention: Other: anal cancer
15 Not yet recruiting PK, PD and Safety Comparative Trial of Isosorbide Mononitrate Gel in Healthy Participants and With Anal Fissure
Condition: Anal Fissure
Intervention: Drug: Isosorbide Mononitrate
16 Not yet recruiting Trial on Use of Coloshield in Transanal and Anal Surgery
Conditions: Fistula-in-ano;   Rectal Polyp;   Rectal Adenoma;   Hemorrhoids;   Anal Fissure
Interventions: Device: Coloshield;   Other: Control
17 Recruiting Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer
Conditions: Anal Basaloid Carcinoma;   Anal Canal Cloacogenic Carcinoma;   Anal Squamous Cell Carcinoma;   Metastatic Anal Canal Carcinoma;   Recurrent Anal Canal Carcinoma;   Stage IIIB Anal Canal Cancer;   Stage IV Anal Canal Cancer
Interventions: Drug: Capecitabine;   Drug: Carboplatin;   Drug: Cisplatin;   Drug: Fluorouracil;   Other: Laboratory Biomarker Analysis;   Drug: Paclitaxel;   Other: Quality-of-Life Assessment
18 Recruiting Quality of Life in Patients With Anal Cancer
Condition: Anal Cancer
19 Recruiting The Effect of Intra-anal Nifedipine, Used As Add-on to Conservative Therapy, on Pain in Patients With Anal Fissure
Condition: Chronic Anal Fissure
Intervention: Drug: Nifedipine
20 Recruiting Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection
Conditions: Anal Squamous Cell Carcinoma;   HIV Infection;   Stage 0 Anal Canal Cancer;   Stage I Anal Canal Cancer
Intervention: Procedure: Therapeutic Conventional Surgery

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