178 studies found for:    Open Studies | "Anemia, Sickle Cell"
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1 Recruiting Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia
Conditions: Peripheral Blood Stem Cell Transplantation;   Anemia, Sickle Cell;   Graft-Versus-Host Disease;   Sirolimus (Rapamune );   Alemtuzumab (Campath )
Interventions: Procedure: PBMC Transplant;   Drug: Alemtuzumab (Campath );   Drug: Sirolimus (Rapamune );   Drug: Cyclophosphamide (Cytoxan );   Procedure: Low Dose Irradiation
2 Unknown  Clinical Importance of Treating Iron Overload in Sickle Cell Disease
Conditions: Anemia, Sickle Cell;   Transfusion Hemochromatosis
Intervention: Drug: deferasirox
3 Recruiting Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease
Condition: Anemia, Sickle Cell
Interventions: Drug: Rivipansel;   Other: Placebo
4 Unknown  A Randomized Trial of LOVAZA in Pediatric Sickle Cell Disease (SCD)
Conditions: Sickle Cell Disease;   HEMOGLOBIN SS;   Hemoglobin S Beta-0 Thalassemia;   Inflammation;   Quality of Life
Interventions: Dietary Supplement: Omega-3 Fatty Acids: Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA);   Other: Placebo Capsules
5 Recruiting Microvascular Blood Flow in Sickle Cell Anemia
Conditions: Sickle Cell Disease;   Sickle Cell Anemia
Interventions: Drug: regadenoson infusion with contrast-enhanced ultrasound;   Procedure: contrast-enhanced ultrasound
6 Recruiting Gene Transfer for Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Anemia
Intervention: Genetic: Gene transfer
7 Recruiting tDCS Associated With Peripheral Electrical Stimulation for Pain Control in Individuals With Sickle Cell Disease
Conditions: Anemia, Sickle Cell;   Chronic Pain
Intervention: Device: tDCS plus PES
8 Recruiting Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Conditions: Pulmonary Hypertension;   Sickle Cell Anemia;   Sickle Cell Disease
Intervention:
9 Recruiting Safety Of Rivipansel (GMI-1070) In The Treatment Of One or More Vaso-occlusive Crises In Hospitalized Subjects With Sickle Cell Disease
Conditions: Sickle Cell Anemia;   Sickle Cell Disease;   Sickle Cell Disorders;   Pain Crisis;   Vaso-occlusive Crisis
Intervention: Drug: Rivipansel
10 Not yet recruiting Desmopressin as a Therapy for Bedwetting in Children With Sickle Cell Disease
Conditions: Nocturnal Enuresis;   Anemia, Sickle Cell
Interventions: Drug: Desmopressin;   Drug: Placebo
11 Recruiting Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease
Condition: Anemia, Sickle Cell
Intervention: Behavioral: Cogmed RM
12 Not yet recruiting A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease Patients
Condition: Anemia, Sickle Cell
Interventions: Drug: SANGUINATE 320 mg/kg;   Drug: Normal Saline
13 Recruiting Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis
Condition: Anemia, Sickle Cell
Interventions: Drug: SANGUINATE;   Drug: Placebo
14 Not yet recruiting Low Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa
Conditions: Sickle Cell Disease;   Sickle Cell Anemia;   Stroke
Interventions: Drug: Moderate Dose Hydroxyurea;   Drug: Low Dose Hydroxyurea
15 Recruiting Improving Self-Management in Adolescents With Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Behavioral: SCThrive Intervention for Adolescents with SCD
16 Recruiting Preventing Sickle Cell Kidney Disease
Conditions: Anemia, Sickle Cell;   Sickle Cell Disease;   Kidney Disease;   Hypertension;   Proteinuria
Intervention: Drug: Losartan
17 Not yet recruiting Oxygen Therapy and Pregnancy in Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Device: oxygen therapy
18 Recruiting Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)
Condition: Sickle Cell Disease
Intervention: Other: SCD Group
19 Recruiting Cardiovascular Complications of Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Procedure: MRI, Transthoracic Echocardiography, tonometry, EKG
20 Recruiting Liver Fibrosis in Sickle Cell Disease
Condition: Sickle Cell Disease
Interventions: Other: Liver transient elastography (Fibroscan);   Other: Ferriscan;   Procedure: Liver biopsy in iron overloaded subjects.

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Indicates status has not been verified in more than two years